Isolation, Identification, and Pathogenicity of Potential Probiotics Isolated from Intestinal Coconut Crab (Birgus latro Linnaeus, 1767) by Muhammad Aris, Tamrin Tamrin, Waode Munaeni, Sudirto Malan, Juharni Juharni, Rusmawati Labenua

“…The isolated used were marked with BL1, BL2, BL3, BL4, and BL5. Molecular identification was performed with sequencing and then analyzed using the Basic Local Alignment Search Tool (BLAST). …”
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Amelioration of Coagulation Disorders and Inflammation by Hydrogen-Rich Solution Reduces Intestinal Ischemia/Reperfusion Injury in Rats through NF-κB/NLRP3 Pathway by Ling Yang, Yan Guo, Xin Fan, Ye Chen, Bo Yang, Ke-Xuan Liu, Jun Zhou

“…The results showed that HRS improved the survival rate and alleviated serum diamine oxidase activities, intestinal injury, edema, and apoptosis. Interestingly, HRS markedly improved intestinal I/R-mediated coagulation disorders as evidenced by abnormal conventional indicators of coagulation and thromboelastography. …”
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Role of Ultrasonography in Monitoring Chemotherapeutic Effects on Primary Thyroid Lymphoma: A Single-Center Retrospective Study by Shirong Liu, Ying Fu, Ligang Cui, Shumin Wang, Shi Tan

“…<i>Results:</i> The sonographic findings for all the patients indicated diffuse or nodular infiltration with markedly hypoechoic masses, and “stripe-shaped” high echoes and posterior acoustic enhancement were observed. …”
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Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization by Bahareh Bahmani, Zahra Amini-bayat, Mohammad Mehdi Ranjbar, Masoud Hassanzadeh Makoui, Amir-Hassan Zarnani

“…Immunization of TC-1 tumor-bearing mice with HPV16-E7, markedly delayed tumor growth and propagation. Conclusion The poly-epitope vaccine for HPV16-E7, as expressed and purified in this research, is highly immunogenic and capable of triggering E7-specific antibodies, making it a potential therapeutic HPV vaccine. …”
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Effects of in-ovo injection of Yu ping feng polysaccharides on growth performance, intestinal development, and immunity in broiler chickens by Li-Gang Xue, Tian-Kui Guo, Juan Wang, Yu-Quan Shan, Li Guo, Dong-Xing Zhang, Zhong Wei, Dan Wang

“…Additionally, the expression of intestinal mucosal immune cytokines, including interleukin (IL)-2, IL-4, IL-6, and interferon-γ, were markedly increased in the duodenum and ileum of the YPF group. …”
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Peripheral blood age-sensitive immune markers in multiple sclerosis: relation to sex, cytomegalovirus status, and treatmentResearch in context by Haritha Desu, Renaud Balthazard, Audrey Daigneault, Sandra Da Cal, Wendy Klément, Jennifer Yu, Marie-Laure Clénet, Clara Margarido, Annie Levert, Canisius Fantodji, Olivier Tastet, Jean-Marc Girard, Pierre Duquette, Alexandre Prat, Gabrielle Macaron, Marie-Claude Rousseau, Nathalie Arbour, Catherine Larochelle

“…IL-4 and β-NGF levels were lower in untreated PwMS compared to controls, while EGF and bFGF levels were influenced by age and markedly elevated in PwMS in multivariable analysis. …”
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Design of low-carbon planning model for vehicle path based on adaptive multi-strategy ant colony optimization algorithm by Qi Guo, Rui Li, Changjiang Zheng, Gwanggil Jeon

“…Moreover, comparative analyses of various optimization methods on the custom-built dataset reveal that the ant colony optimization algorithm markedly outperforms the simulated annealing algorithm (SA) and particle swarm optimization algorithm (PSO). …”
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Four cardiomyopathy patients with a heterozygous DSG2 p.Arg119Ter variant by Takuya Sumida, Shou Ogawa, Shuichiro Higo, Yuki Kuramoto, Ryo Eto, Yoshihiko Ikeda, Congcong Sun, Junjun Li, Li Liu, Tomoka Tabata, Yoshihiro Asano, Mikio Shiba, Yasuhiro Akazawa, Daisuke Nakamura, Takafumi Oka, Tomohito Ohtani, Yasushi Sakata

“…Immunohistochemical analysis of endomyocardial biopsy samples revealed that the expression of not only desmoglein-2 but also desmoplakin was markedly reduced. Transmission electron microscopy revealed pale and fragmented desmosomes and widened gaps between intercalated discs in the myocardium. …”
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Circulating Clusterin and Osteopontin Levels in Asthma and Asthmatic Pregnancy by Brigitta Dombai, István Ivancsó, András Bikov, Dóra Oroszi, Anikó Bohács, Veronika Müller, János Rigó, Barna Vásárhelyi, György Losonczy, Lilla Tamási

“…Osteopontin levels of ANP and HNP were similar (2.142 [1.483–2.701] versus 2.075 [1.680–2.331] ng/mL, p=0.7331). Pregnancy caused a marked elevation in both healthy (HP: 3.037 [2.439–4.015] ng/ml, p=0.003 versus HNP) and asthmatic (AP: 2.693 [1.581–3.620] ng/ml) patients; thus the pregnant groups did not differ (p=0.3541). …”
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Changes in Dickkopf-1 (DKK1) and Sclerostin following a Loading Dose of Vitamin D2 (300,000 IU) by A. Sankaralingam, R. Roplekar, C. Turner, R. N. Dalton, G. Hampson

“…Serum 1,25 (OH)2 vitamin D increased markedly at 3 months (mean (SD) baseline 116 (63), 3 months : 229 (142) pmol/L, P<0.001). …”
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Prediction of Soil Organic Carbon Content in <italic>Spartina alterniflora</italic> by Using UAV Multispectral and LiDAR Data by Jiannan He, Yongbin Zhang, Mingyue Liu, Lin Chen, Weidong Man, Hua Fang, Xiang Li, Xuan Yin, Jianping Liang, Wenke Bai, Fuping Li

“…Slope aspect (AS) was identified as the most influential topographic feature. 4) The spatial distribution of SOC exhibited marked heterogeneity, with higher SOC content in ULSA and lower in mudflats, demonstrating a gradient of decreasing SOC content from land to sea. …”
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Socioeconomic position and breast cancer screening use in Chile: A population-based study by Camilo Guerrero-Nancuante, Pamela Eguiguren, Isabel Abarca-Baeza, Isabel Guzmán, María Luisa Garmendia

“…Although several studies have examined the relationship between socioeconomic factors and mammography use, the impact of socioeconomic position (SEP) in countries undergoing demographic and epidemiological transitions—marked by a rising cancer incidence—and passive breast cancer screening programs in the search of the target population remains understudied. …”
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Association among financial toxicity, depression and fear of cancer recurrence in young breast cancer patient-family caregiver dyads: an actor-partner interdependence mediation mod... by Tianye Yang, Zhu Zhu, Jianjun Shi, Lingling Tong, Jia Yang, Songli Mei, Hui Ren

“…Furthermore, financial toxicity in both young BC patients and family caregivers markedly affected both the actor and partner effects on dyadic depression, primarily through the patients’ FCR. …”
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miR-182 promoter hypermethylation predicts the better outcome of AML patients treated with AZA + VEN in a real-world setting by Yilan Xu, Danyang Li, Na Wang, Bei Ge, Chen Meng, Min Zhao, Zihan Lin, Min Li, Yigang Yuan, Yue Cai, Liuzhi Shi, Shenmeng Gao, Haige Ye

“…Results The average methylation frequency was markedly higher in 94 AZA + VEN-treated elderly or unfit AML patients than that in 20 NCs. …”
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Regional disparities and dynamic adaptation in the forest health-based industry and ecological environment: A case study of Fujian Province, China by Wenyu Chen, Shuhan Yu, Xuwang Jiang, Liyu Zhan

“…In contrast, Zhangzhou and Nanping face more significant challenges that require attention and improvement. Lower levels mark the adaptability pattern in peripheral areas. …”
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Genomic data suggest parallel dental vestigialization within the xenarthran radiation by Emerling, Christopher A, Gibb, Gillian C, Tilak, Marie-Ka, Hughes, Jonathan J, Kuch, Melanie, Duggan, Ana T, Poinar, Hendrik N, Nachman, Michael W, Delsuc, Frédéric

“…Echoes of this event are recorded in the genomes of all living anteaters, being marked by a 2-bp deletion in a gene critical for dentinogenesis (DSPP) and a putative shared 1-bp insertion in a gene linked to tooth retention (ODAPH). …”
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EU-TIRADS-Based Omission of Fine-Needle Aspiration and Cytology from Thyroid Nodules Overlooks a Substantial Number of Follicular Thyroid Cancers by Tamas Solymosi, Laszlo Hegedüs, Miklos Bodor, Endre V. Nagy

“…In such nodules (n = 118), the number of suspicious features (marked hypoechogenicity, microcalcifications, irregular shape, and irregular border) per lesion was lower in FTC (0.7 ± 0.6) than in PTC (1.7 ± 1.0) or MTC (1.8 ± 0.7; p<0.02), resulting in EU-TIRADS scores of 4.1 ± 0.6, 4.8 ± 0.3, and 4.9 ± 0.2, respectively (p<0.01). …”
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Therapeutic Effects of the Combination of Alpha-Lipoic Acid (ALA) and Coenzyme Q10 (CoQ10) on Cisplatin-Induced Nephrotoxicity by Eman Aly Khalifa, Ahmed Nabil Ahmed, Khalid Shaaban Hashem, Ahmad Gad Allah

“…MDA level was significantly lower when combination therapy was used. Marked renal damage was histologically detected in the cisplatin group, whereas the least renal damage was noticed in the combination group. …”
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Collecting duct NCOR1 controls blood pressure by regulating mineralocorticoid receptor by Ke Sun, Yong-Li Wang, Chen-Chen Hou, Da Shang, Lin-Juan Du, Lan Bai, Xing-Yu Zhang, Chuan-Ming Hao, Sheng-Zhong Duan

“…Among the sodium transporter in the collecting duct, the expression of the three epithelial sodium channel (ENaC) subunits was markedly increased in the renal medulla of KO mice. …”
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Cobalt oxide nanoparticles induce cytotoxicity and excessive ROS mediated mitochondrial dysfunction and p53-independent apoptosis in melanoma cells by Hanan R. H. Mohamed, Basma A. Mohamed, George M. Hakeem, Shahd H. Elnawasani, Maria Nagy, Rawan Essam, Ayman Diab, Gehan Safwat

“…Results of qRT-PCR analysis demonstrated remarkable dysregulation of apoptotic and mitochondrial genes, including a significant downregulation of apoptotic p53 and mitochondrial ND3 genes and marked upregulation of the anti-apoptotic gene Bcl2. …”
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