Characterization and Outcome of Two Pediatric Intensive Care Units with Different Resources by Rania G. Abdelatif, Montaser M. Mohammed, Ramadan A. Mahmoud, Mohamed A. M. Bakheet, Masafumi Gima, Satoshi Nakagawa

“…Both actual and PIM-2 predicted mortalities were markedly higher for patients admitted to the Egyptian unit, and the mortality was significantly associated with age, severe sepsis, and PIM-2. …”
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Landscape composition and orchard management effects on bat assemblages and bat foraging activity in apple crops by Marcos Miñarro, Daniel García

“…We found that bat assemblages markedly varied across orchards, according mostly to landscape composition gradients but with contrasting landscape effects on different assemblage characteristics. …”
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The collaborative cross mouse for studying the effect of host genetic background on memory impairments due to obesity and diabetes by Avia Paz, Kareem Midlej, Osayd Zohud, Iqbal M. Lone, Fuad A. Iraqi

“…Glucose tolerance tests revealed significant variations, with some lines like CC005 showing a marked increase in area under the curve (AUC) values on HFD. …”
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Foliar image-based characterization of airborne particulate matter in an urban area and its implications for remediation by Ankesh Tiwari, Triratnesh Gajbhiye, Mohineeta Pandey, Kajal Agrawal, Shuvadarshini Naik, Shubhrasmita Meher, Dinesh Patel, Rashmi Dubey, Tanzil Gaffar Malik, Mohammed Zari, Ali Zari, Khalid M Alghamdi, Khalid Rehman Hakeem, Sudhir Kumar Pandey

“…Senna Siamea and Dalbergia Sissoo are identified as top choices for effective PM removal, marking a significant step towards sustainable urban environments. …”
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Pioglitazone Attenuates Drug-Eluting Stent-Induced Proinflammatory State in Patients by Blocking Ubiquitination of PPAR by Zhongxia Wang, Tao Zhang, Lizhe Sun, Ruifeng Li, Yuanyuan Wei, Xiaojuan Fan, Zuyi Yuan, Junhui Liu, Tao Chen

“…DES-induced mRNA expressions of IL-6, TNF-α, and MMP-9 in circulating MNC were significantly blocked by PIO (P=0.031, 0.012, and 0.007, resp.). In addition, PIO markedly inhibited DES-enhanced NF-κB function and DES-blocked PPAR-γ activity. …”
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A Study of Hypothyroidism in Chronic Kidney Disease (CKD) Patients by Sudharsanan V, Prabhu Shankar S, Viknesh V

“…Hypothyroidism, a condition marked by deficient thyroid hormone levels, is known to affect patients with CKD through impacts on thyroid metabolism. …”
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Portable devices for periodic monitoring of bioelectrical impedance along meridian pathways in healthy individuals by Yu-Chen Xu, Xiu-Yan Cao, Shuai Liu, Bo Liu, Hao Chen, Min Cheng, Wei-Hua Ye

“…The second group, comprising the spleen, stomach, bladder, kidney, gallbladder, and liver meridians, exhibited marked differences primarily between March and April (P < 0.05), with a peak in April and relatively stable values thereafter. …”
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CK2α-mediated phosphorylation of DUB3 promotes YAP1 stability and oncogenic functions by Lei Huang, Yalei Wen, Qin Guo, Caishi Zhang, Xiao Yang, Mei Li, YiXia Liu, Xinying Li, Jiaxin Tang, Xiaofeng Zhou, Qi Qi, Haoxing Zhang, Tongzheng Liu

“…Pharmacological inhibition of Casein kinase II by Silmitasertib or genetic depletion of the catalytic subunit of Casein kinase II (CK2α) markedly destabilizes YAP1 and consequently suppresses its oncogenic functions in vitro and in vivo. …”
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Electroacupuncture Alleviates Neuropathic Pain through Regulating miR-206-3p Targeting BDNF after CCI by Wenzhan Tu, Jingjing Yue, Xuqing Li, Qiaoyun Wu, Guanhu Yang, Shengcun Li, Qiangsan Sun, Songhe Jiang

“…Hyperalgesia was reduced markedly by EA in the CCI model. The expression level of miR-206-3p was elevated, whereas the expression levels of BDNF, BAX/Bcl-2, TNF-α, and IL-6 were decreased in EA-treated CCI rats. …”
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Effects of GABA Supplementation on Intestinal SIgA Secretion and Gut Microbiota in the Healthy and ETEC-Infected Weanling Piglets by Yuanyuan Zhao, Jing Wang, Hao Wang, Yonggang Huang, Ming Qi, Simeng Liao, Peng Bin, Yulong Yin

“…Meanwhile, we observed that some low-abundance microbes, like Enterococcus and Bacteroidetes, were markedly increased in GABA-supplemented groups. KEGG enrichment analysis revealed that the nitrogen metabolism, sphingolipid signaling pathway, sphingolipid metabolism, and microbial metabolism in diverse environments were enriched in the GABA1 group. …”
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Do dogs preferentially encode the identity of the target object or the location of others’ actions? by Lucrezia Lonardo, Christoph J. Völter, Robert Hepach, Claus Lamm, Ludwig Huber

“…Dogs (Canis familiaris) constitute interesting comparative models for the study of action perception due to their marked sensitivity to human actions. We tested companion dogs (N = 21) in two screen-based eye-tracking experiments, adopting a task previously used with human infants and apes, to assess which aspects of an agent’s action dogs consider relevant to the agent’s underlying intentions. …”
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Improving diagnostics and surveillance of malaria among displaced people in Africa by Toufik Abdul-Rahman, Oyinbolaji Akinwande Ajetunmobi, Gafar Babatunde Bamigbade, Innocent Ayesiga, Muhammad Hamza Shah, Tolulope Sharon Rumide, Abdurahman Babatunde Adesina, Ganiyat Adekemi Adeshina, Oluwabusola Elizabeth Oni, Bet-ini Nsikak Christian, Abdullahi Tunde Aborode, Andrew Awuah Wireko, Hala Ibrahim Thaalibi, Iman Mustafa Abdalla, Sewar Basheer Banimusa, Justice Ndubuisi Jonathan, Isreal Ayobami Onifade, Md Ariful Haque

“…Furthermore, the psychological impact of malaria, which is marked by feelings of anxiety and uncertainty, is particularly severe in vulnerable populations such as displaced children and pregnant women, aggravating the overall burden. …”
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The Effect of the Glucosinolate Sinigrin on Alterations in Molecular Biomarkers of the Myocardium in Swiss Mice by Nikola Ferara, Vedran Balta, Domagoj Đikić, Dyana Odeh, Ana Mojsović-Ćuić, Lana Feher Turković, Dario Dilber, Anđelo Beletić, Irena Landeka Jurčević, Ivana Šola

“…Our findings revealed that subchronic exposure to sinigrin in the myocardia of female mice resulted in a significant increase (<i>p</i> ≤ 0.05) in the levels of the myokine irisin, matrix metalloproteinases (MMP-2, MMP-9), catalase (CAT), and total glutathione (tGSH), alongside a marked decrease (<i>p</i> ≤ 0.05) in the levels of atrial natriuretic peptide (ANP), compared to the control group consisting of both female and male mice. …”
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Hypertensive disorders of pregnancy affected thyroid hormone synthesis via endoplasmic reticulum stress in preterm infant rats by Maomao Sun, Congrong Wu, Jie Jiang, Yue He, Sha Zhu, Yonghui Yu

“…While electron microscopy revealed that the endoplasmic reticulum of thyroid follicular epithelial cells was marked swollen within L-NAME group. Additionally, the mRNA expression of Ttf1, Pax8 and Tshr was down-regulated in thyroid tissues of L-NAME group. …”
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Multi-generational adaptation to Solanum nigrum increases reproduction and decreases microbial diversity of Aphis gossypii by Peng Wang, Peng Wang, Yu-Xi Jing, Ya-Jie Ma, Ya-Jie Ma, Dan Wang, Yong-Pan Shan, Hongyan Hu, Changcai Wu, Xian-Peng Song, Xiangliang Ren, Xiangliang Ren, Xiangliang Ren, Yan Ma, Yan Ma, Yan Ma, Xiaoyan Ma, Xiaoyan Ma, Xiaoyan Ma

“…The relative abundance of Buchnera in T5 and T10 significantly increased compared to M and T, while the relative abundance of Arsenophonus decreased markedly. KEGG (Kyoto Encyclopedia of Genes and Genomes) function prediction analysis suggested that the roles of symbiotic bacteria in A. gossypii are primarily linked to metabolic processes. …”
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NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats by Zheng-De Du, Wei Wei, Shukui Yu, Qing-Ling Song, Ke Liu, Shu-Sheng Gong

“…The auditory brainstem response (ABR) of ZDF rats was found to be markedly elevated in low (8 kHz) and high (32 kHz) frequencies. …”
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Octreotide in Intestinal Lymphangiectasia: Lack of a Clinical Response and Failure to Alter Lymphatic Function in a Guinea Pig Model by S Makhija, P-Y vod der Weid, J Meddings, SJ Urbanski, PL Beck

“…In this model system, the mesenteric lymphatic vessels responded to 5-hydroxytryptamine with a decrease in constriction frequency, while histamine administration markedly increased lymphatic constriction frequency. …”
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LncRNA HOTAIR: A Novel Biomarker for the Diagnosis of Asymptomatic Carotid Artery Stenosis and Prediction of the Onset of Cerebral Ischemic Events by Pengcheng Feng, Chenguang Tong, Yuan Li, Li Liu

“…Results Serum HOTAIR was markedly lower in ACAS patients than in controls (P < 0.001). …”
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New Echocardiographic Findings Correlate with Intramyocardial Inflammation in Endomyocardial Biopsies of Patients with Acute Myocarditis and Inflammatory Cardiomyopathy by Felicitas Escher, Mario Kasner, Uwe Kühl, Johannes Heymer, Ursula Wilkenshoff, Carsten Tschöpe, Heinz-Peter Schultheiss

“…In the acute phase patients had markedly decreased left ventricular (LV) systolic function (mean LV ejection fraction (LVEF) 40.4±10.3%). …”
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Prevalence and risk factors of hyperuricaemia in non-obese Chinese: a single-centre cross-sectional study by Chengfu Xu, Jinghua Wang, Xinyu Wang, Yishu Chen, Shenghui Chen, Haoliang Zhai

“…The prevalence of hyperuricaemia markedly increased in women aged above 50 years. The prevalence of hyperuricaemia was significantly higher in metabolically unhealthy participants with normal weight than in metabolically healthy participants with normal weight. …”
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