Novel Mechanisms Modulating Palmitate-Induced Inflammatory Factors in Hypertrophied 3T3-L1 Adipocytes by AMPK by Naru Morita, Toshio Hosaka, Atsuko Kitahara, Toshitaka Murashima, Hirohisa Onuma, Yoshikazu Sumitani, Kazuto Takahashi, Toshiaki Tanaka, Takuma Kondo, Hitoshi Ishida

“…In addition, the AMPK activator not only markedly diminished MCP-1 secretion but also augmented phosphorylation of nuclear factor-κB (NF-κB) and extracellular signal-regulated kinase (ERK) 1/2. …”
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Influence of Angiotensin II Subtype 2 Receptor (AT2R) Antagonist, PD123319, on Cardiovascular Remodelling of Aged Spontaneously Hypertensive Rats during Chronic Angiotensin II Subt... by Emma S. Jones, M. Jane Black, Robert E. Widdop

“…Mean arterial pressure (MAP) and left ventricular volume were markedly decreased by candesartan cilexetil, however, simultaneous treatment with PD123319 had no additional effect on either parameter. …”
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Educational frontiers with ChatGPT: a social network analysis of influential tweets by Mehmet Firat, Saniye Kuleli

“… The unprecedented adoption of OpenAI's ChatGPT, marked by reaching 100 million daily users in early 2023, highlights the growing interest in AI for educational improvement. …”
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Experimental Analysis of Fuzzy Gain-Scheduled PID Controller With a Feedforward Compensator for an Ultra-Precise Piezoactuated Micropositioning Stage by Hussain Kahil, Irfan Ahmad, Yasser Bin Salamah

“…The peak-to-peak tracking error is 0.5% of the <inline-formula> <tex-math notation="LaTeX">$12\mu $ </tex-math></inline-formula>m, 10Hz reference trajectory, marking a 54% and 88% performance improvement over the intelligent fuzzy controller, and classical PID controller, respectively.…”
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Maternal exposure to tris (2-butoxyethyl) phosphate induces F0 female reproductive toxicity and offspring developmental toxicity in zebrafish by Anqi Dong, Wenqian Lei, Weiqi Zhou, Wenwen Li, Jianghua Wang

“…The observed impacts on the F0 generation were linked to a marked decrease in 17β-estradiol concentrations and disruptions in the gene expression patterns along the hypothalamic-pituitary-gonadal-liver (HPGL) axis. …”
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Severe Hypotension, Hypoxia, and Subcutaneous Erythema Induced by Indigo Carmine Administration during Open Prostatectomy by Koichiro Nandate, Bryan B. Voelzke

“…Within 1 minute after injection of indigo carmine for evaluation of the ureters, the patient developed hypotension to 40 mmHg, severe hypoxia (the value of SpO2 (peripheral capillary oxygen saturation) was 75% on 40% inspired oxygen concentration), poor air movement and bilateral diffuse wheezing on auscultation, and marked subcutaneous erythema at the upper extremities. …”
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Biodegradable Oxygen‐Generating Microneedle Patches for Regenerative Medicine Applications by Lindsay Barnum, Mohamadmahdi Samandari, Yasir Suhail, Steven Toro, Ashkan Novin, Pejman Ghelich, Jacob Quint, Farnooosh Saeedinejad, Manu Komma, Kshitiz, Ali Tamayol

“…Additionally, transcriptomic analysis reveals upregulation of key pathways related to fibroblast motility, lipid metabolism, and a marked reduction in inflammatory signaling, all of which contribute to improved wound healing. …”
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X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women by Tao Zhang, Yanting Liu, Fang Liu, Kaiyu Guo, Runhua Tang, Jingwei Ye, Li Xue, Zhipeng Su, Zhe Bao Wu

“…Further investigation revealed that USP11 expression is markedly elevated in female functioning ACTH PitNETs, with levels significantly higher than those observed in male PitNETs and normal pituitary tissue. …”
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Fluid-structure interaction analysis for abdominal aortic aneurysms: the role of multi-layered tissue architecture and intraluminal thrombus by Xinhai Yue, Jiayi Huang, Ju Liu

“…IntroductionAbdominal aortic aneurysm (AAA) is a life-threatening disease marked by localized dilatations of the infrarenal aortic wall. …”
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LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis by Yasuka Matsunaga, Yusuke Nakatsu, Toshiaki Fukushima, Hirofumi Okubo, Misaki Iwashita, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Akifumi Kushiyama, Shin-ichiro Takahashi, Yoshihiro Tsuchiya, Hideaki Kamata, Fuminori Tokunaga, Kazuhiro Iwai, Tomoichiro Asano

“…The reduction of LUBAC is likely to be attributable to markedly reduced expression of SHARPIN, one of its components. …”
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REVEALED COMPARATIVE ADVANTAGE IN TRADE BETWEEN THE REPUBLIC OF MACEDONIA AND CEFTA 2006 by Emilija Miteva-Kacarski

“…The RCA and RSCA indices mark down positive values in the category of crude materials inedible (except fuels) and in the category of chemical products whereas the CEP index calculated for the category of tobacco and beverages shows a significant comparative advantage of the Republic of Macedonia over other CEFTA 2006 member states. …”
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Inhibitory Effect of L-Methionine-Modified Microcrystalline Cellulose on Gram-Positive Bacteria by WU Simiao, YANG Haifan, LIANG Guannan, SUN Xinyang

“…M-MCC had a good scavenging effect on 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) cationic radicals, with a scavenging percentage of 97.47% at 20 mg/mL. M-MCC had a marked antibacterial activity against the Gram-positive bacteria Listeria monocytogenes and Staphylococcus aureus, with minimal inhibitory concentration and minimum bactericidal concentration of 15 and 30 mg/mL, respectively. …”
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Reaction kinetics and molecular characterization of the compounds formed by photosensitized degradation of the plastic additive bisphenol A in the atmospheric aqueous phase by Yiting Wang, Qingxin Deng, Yiqun Wang, Pan Li, Biao Jin, Jiangping Liu, Peng Cheng, Marcello Brigante, Dario D’Antuono, Luca Carena, Hui Chen, Davide Vione, Sasho Gligorovski

“…Ultra-high resolution mass spectrometry revealed that the presence of inorganic salts (NaCl and NaBr) markedly increased the complexity of the observed CHO product compounds formed upon photosensitized degradation of BPA. …”
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Electroacupuncture Improves Baroreflex and γ-Aminobutyric Acid Type B Receptor-Mediated Responses in the Nucleus Tractus Solitarii of Hypertensive Rats by Qi Zhang, Ying-Ying Tan, Xiao-hua Liu, Fan-Rong Yao, Dong-Yuan Cao

“…The results showed that long-term EA treatment improved blood pressure (BP) and markedly restored the baroreflex response in 2K1C hypertensive rats. …”
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Global, regional, and national burden of esophageal cancer using the 2019 global burden of disease study by Liangchao Sun, Kaikai Zhao, Xiaoli Liu, Xue Meng

“…Over the past three decades, esophageal cancer has exhibited a substantial global burden, marked by a significant increase in absolute numbers, contrasting with a decline in age-standardized metrics. …”
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Association between frailty and hospital-related adverse events in older hospitalised patients: a systematic literature review protocol by Jay Banerjee, Brad Manktelow, Abdullah Alshibani, Faris Alotaibi

“…Frailty is a syndrome marked by increased vulnerability, sudden and severe health changes and the risk of adverse outcomes. …”
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Effect of drought disturbance in a sclerophyll forest on the micromammal community in the Río Clarillo National Park, Metropolitan Region, Chile by Susan Fletcher, Carlos Sarmiento, Gisela C. Stotz, Verónica Quirici

“…To study the community of micromammals in these forests, the Capture-Mark-Recapture method was used with Sherman traps. …”
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Ethanolic Extract of Red Okra Pods Induces Aberrant Spindle Segregation and Apoptotic Cell Death by Disrupting the Wnt Signaling Pathway in Colon Cancer Cells by Firli Rahmah Primula Dewi, Sri Puji Astuti Wahyuningsih, Vuanghao Lim, Lionel Lian Aun In, Alfiah Hayati

“…Results: EEROP treatment induced apoptosis in SW480 cells, marked by elevated levels of active caspase-3 (P<0.001) and cleaved poly-(ADP-ribose) polymerase (PARP)-1. …”
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The Balance of Th1/Th2 and LAP+Tregs/Th17 Cells Is Crucial for Graft Survival in Allogeneic Corneal Transplantation by Shang Li, Jing Yu, Chungang Guo, Ying Jie, Zhiqiang Pan

“…The level of IFN-γ, TNF, IL-6, and IL-17A markedly increased in aqueous humor during corneal allograft rejection. …”
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Characterization of olive mill wastewater in three climatic zones in the North of Jordan by Mamoun Gharaibeh, A. Albalasmeh Ammar, Hanady Abu Abbas

“…Principal component analysis (PCA) showed that total phenols had high loadings in favour with Ca, and TSS in arid, total nitrogen in the semi-arid, and COD in the sub-humid climates.Conclusion OMW properties were markedly affected by the climate. PCA showed that climate mainly affected the organic loading of extracted components. …”
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