The Mitigating Effect of Citrullus colocynthis (L.) Fruit Extract against Genotoxicity Induced by Cyclophosphamide in Mice Bone Marrow Cells by Mohammad Shokrzadeh, Aroona Chabra, Farshad Naghshvar, Amirhossein Ahmadi

“…At 200 mg/kg, CCT had a maximum chemoprotective effect and reduced the number of MnPCEs by 6.37-fold and completely normalized the mitotic activity. CCT also led to marked proliferation and hypercellularity of immature myeloid elements after mice were treated with CP and mitigated the bone marrow suppression. …”
Get full text

Antipleuritic and Vascular Permeability Inhibition of the Ethyl Acetate-Petroleum Ether Stem Bark Extract of Maerua angolensis DC (Capparaceae) in Murine by Felix Agyei Ampadu, Eric Boakye-Gyasi, Newman Osafo, Charles Kwaku Benneh, Edmund Ekuadzi, Eric Woode

“…Vascular permeability was also attenuated by the extract with marked reduction of Evans blue dye leakage in acetic acid induced permeability assay. …”
Get full text

Value of the New Spline QTc Formula in Adjusting for Pacing-Induced Changes in Heart Rate by Hirmand Nouraei, Matthew Bennett, Simon Rabkin

“…In contrast, the Bazett formula (QTcBZT) showed a steep and marked increase in QTc with shorter RR intervals. …”
Get full text

Hepatitis in Disseminated Bacillus Calmette-Guérin Infection by Markus U Göttke, Philip Wong, Channy Muhn, Mansour Jabbari, Suzanne Morin

“…Clinical improvement was marked and sustained so that the patient could be discharged home for the full six-month course of his treatment. …”
Get full text

Research on LoRa network security schemes based on RF fingerprint by Yu JIANG, Siqing CHEN, Wen SUN

“…Long range radio (LoRa) is widely used in the IoT due to its advantages of long distance and low power consumption.However, LoRa network has no reliable security scheme currently, making it unable to guarantee the communication security.Therefore, based on the uniqueness and tamper-resistance of radio frequency fingerprint, it was proposed to receive radio frequency signals of the LoRa end nodes which requested access, extract the fingerprints from them, mark it and match with the customized multi-scale security rules according to demands to decide whether the identities of the LoRa end nodes were safe, taking security measures accordingly.Based on this, original LoRa gateway and LoRa network architecture were improved, new workflows were designed, and two LoRa network security schemes were proposed.The two LoRa network security schemes were proposed which implement identity authentication and access control of the LoRa end nodes from the physical layer.It is only needed to improve the original LoRa gateway in the LoRa network architecture and its workflow, which adds new security measures and guarantees for LoRa applications on the basis of not affecting the original LoRaWAN security mechanism, with no need to modify a huge number of LoRa end nodes.The security schemes proposed have high practical value.…”
Get full text

Lipoic acid-boronophenylalanine-derived multifunctional vesicles for cancer chemoradiotherapy by Liqun Dai, Jie Liu, Tingyu Yang, Xiaorui Yu, Yi Lu, Lili Pan, Siming Zhou, Diyun Shu, Yuanhao Liu, Wuyu Mao, Zhiyong Qian

“…Our findings highlight the potential of LA-BPA derivatives in developing more precise, effective, and less detrimental chemoradiotherapy approaches, marking an advancement in nanomedicine for cancer treatment.…”
Get full text

Analysis of the sexual dimorphism of metric variables of the cranial base: Archaeo-anthropological and forensic implications by Alexandra Boucherie

“…The study shows how the expression of this sexual dimorphism becomes more marked on the temporal bone as from the pubertal growth peak. …”
Get full text

Trypsin-instructed bioactive peptide nanodrugs with cascading transformations to improve chemotherapy against colon cancer by Can Wu, Xiao Wei Zhang, Manman Wang, Jinpan Sun, Jianfei Chen, Yanbin Guan, Xin Pang

“…Abstract Chemotherapy remains an effective treatment for colon cancer but is hampered by its limited response rate. Bioactive peptides, marked with intracellular transformations, have been reported as an effective approach to boosting chemotherapeutic activity. …”
Get full text

Induced protein expression in Leptospira spp. and its application to CRISPR/Cas9 mutant generation by L. G. V. Fernandes, A. L. T. O. Nascimento, J. E. Nally

“…The advent of the CRISPR/Cas9 system has marked a turning point in genetic manipulation, with applications across multiple Leptospira species. …”
Get full text

Association of Taiwan’s Rainfall Patterns with Large-Scale Oceanic and Atmospheric Phenomena by Yi-Chun Kuo, Ming-An Lee, Mong-Ming Lu

“…Because of Taiwan’s geographic location and the effect of local terrestrial structures, climate variability related to ENSO differed markedly from other regions in East Asia.…”
Get full text

Reflections on the ecclesiastical interpretations of 6th April 1652 as a South African symbolic date by R. M. Britz

“… This article verifies the theological interpretation of the 6th April 1652 as a South African symbolic date, which marked the beginning of the European and Christian contribution to the history of Southern Africa. …”
Get full text

A study on critical dislocation of gasket for segmental linings of shield tunnels by Xuan Guo, Zhitong Li, Senyang Yuan

“…A dislocation of 9 mm and an opening of 8 mm yield the lowest effective contact stress proportion and worst waterproof performance, marking a critical point for sealing water pressure changes. …”
Get full text

Serum Amyloid A as a Marker of Persistent Inflammation and an Indicator of Cardiovascular and Renal Involvement in Patients with Rheumatoid Arthritis by Bożena Targońska-Stępniak, Maria Majdan

“…The mean SAA concentration was significantly higher in patients treated with glucocorticoids, was inversely associated with QTc duration, and was markedly higher in patients with atherosclerotic plaques, emphasizing increased CV risk. …”
Get full text

Latitudinal Variation into the Macrofaunal Assemblages Associated to Zostera noltei Seagrass along the Atlantic Coast of Morocco by Oussama Bououarour, Soilam Boutoumit, Reda El Kamcha, Hocein Bazairi

“…However, such patterns could be related to other factors such as habitat heterogeneity and regional, biogeographic, and anthropogenic factors. The present study marked the first attempt on broad-scale ecological research of seagrass beds in Morocco and offers baseline data for planning the broad-scale conservation of biodiversity in seagrass beds that remain suffering from multiple human-induced threats such as coastal developments and climate change.…”
Get full text

The Relevance of Biblical Exegesis to the Study of the Dynamics of the Educational Relationship in Contemporary Pedagogy. An Example of the Biblical Story of the Calling of Levi by Leszek Waga

“…The interpretative possibilities of this story, or rather of the one sentence linking the calling with the description of the meal (Mark 2:15), will be presented in the light of contemporary possibilities of biblical exegesis. …”
Get full text

Dissipation Alters Modes of Information Encoding in Small Quantum Reservoirs near Criticality by Krai Cheamsawat, Thiparat Chotibut

“…Our key results show that, near a critical point marking a dynamical bifurcation, the system transitions from predominantly redundant to synergistic encoding. …”
Get full text

Hypervirulent Klebsiella pneumoniae (hvKp): Overview, Epidemiology, and Laboratory Detection by Dania Al Ismail, Edgar I. Campos-Madueno, Valentina Donà, Andrea Endimiani

“…The hypermucoviscous (hmv) phenotype, generally marked by overproduction of the capsule, is often associated with hvKp, although recent studies show that some cKp strains may also have this characteristic. …”
Get full text

PET Study in a Patient with Spinocerebellar Degeneration before and after Long-Term Administration of Thyrotropin Releasing Hormone by H. Tanji, H. Nagasawa, T. Hayashi, H. Onodera, T. Fujiwara, M. Itoh, T. Ido, Y. Itoyama

“…A 56-year-old female, who had suffered from progressive ataxia for 2 years, was treated by intravenous administration of 2 mg TRH for 3 weeks, and CMRG1c of the brain was measured before and after treatment. CMRG1c was markedly decreased in the cerebellum and there was no significant difference before and after the treatment, i.e. mean CMRG1c values were 4.92 and 4.90 mg/100 g/min, and the ratios of the cerebellum versus the frontal cortex were 0.50 and 0.51, respectively. …”
Get full text

Genetically Modified Lactococcus lactis for Delivery of Human Interleukin-10 to Dendritic Cells by Inge L. Huibregtse, Sebatian A. Zaat, Martien L. Kapsenberg, Maria A. Sartori da Silva, Maikel P. Peppelenbosch, Sander J. H. van Deventer, Henri Braat

“…lactisIL-10 induced effector Th-cells that markedly suppressed the proliferation of allogenic Th-cells as compared to L. lactis. …”
Get full text

Metastatic Extrapulmonary Small Cell Carcinoma to the Cerebellopontine Angle: A Case Report and Review of the Literature by Debebe Theodros, C. Rory Goodwin, Genevieve M. Crane, Jason Liauw, Lawrence Kleinberg, Michael Lim

“…Preoperative MRI eight weeks later demonstrated marked enlargement to 35 mm. The patient underwent a suboccipital craniectomy and the mass was grossly different visually and in consistency from a standard vestibular schwannoma. …”
Get full text