Novel Implications in Molecular Diagnosis of Lynch Syndrome by Raffaella Liccardo, Marina De Rosa, Paola Izzo, Francesca Duraturo

“…Moreover, it could also be possible that the simultaneous presence of these genetic variants in several MMR genes that behave as low risk alleles might contribute in a cooperative manner to increase the risk of hereditary cancer. …”
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Transformer-Based Model for Monocular Visual Odometry: A Video Understanding Approach by Andre O. Francani, Marcos R. O. A. Maximo

“…We contribute by presenting the TSformer-VO model based on spatio-temporal self-attention mechanisms to extract features from clips and estimate the motions in an end-to-end manner. Our approach achieved competitive state-of-the-art performance compared with geometry-based and deep learning-based methods on the KITTI visual odometry dataset, outperforming the DeepVO implementation highly accepted in the visual odometry community. …”
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A deep learning‐based attack on text CAPTCHAs by using object detection techniques by Jiawei Nian, Ping Wang, Haichang Gao, Xiaoyan Guo

“…The attack was also evaluated on four click‐based CAPTCHAs that cannot be attacked in the end‐to‐end manner used by previous attacks, and the results demonstrated that within one step, the proposed approach achieves high success rates on both click‐based CAPTCHAs and schemes based on large‐scale character sets, such as Chinese character sets.…”
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A Gamified Active-Learning Proposal for Higher-Education Heterogeneous STEM Courses by Mario J. Duran, Juan J. Aciego, Ignacio Gonzalez-Prieto, Juan Carrillo-Rios, Angel Gonzalez-Prieto, Alicia Claros-Colome

“…A full subject design is presented in a comprehensive manner aiming for satisfying courses with a heterogeneous students’ profile. …”
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Blood glucose-lowering activity of protocatechuic acid is mediated by inhibiting α-glucosidase by Huafang Ding, Shouhe Huang, Chui Yiu Chook, Erika Kwek, Chi Yan, Kaying Ma, Jianhui Liu, Hanyue Zhu, Zhenyu Chen

“…Driven by hydrogen bonds and van der Waals interactions, PCA reversibly bound with α-glucosidase to form a stable α-glucosidase-PCA complex in a spontaneous manner. The computational simulation found that PCA could insert into the active cavity of α-glucosidase and establish hydrogen bonds with catalytic amino acid residues. …”
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Defense against Malicious Users in Cooperative Spectrum Sensing Using Genetic Algorithm by Noor Gul, Ijaz Mansoor Qureshi, Atif Elahi, Imtiaz Rasool

“…In cognitive radio network (CRN), secondary users (SUs) try to sense and utilize the vacant spectrum of the legitimate primary user (PU) in an efficient manner. The process of cooperation among SUs makes the sensing more authentic with minimum disturbance to the PU in achieving maximum utilization of the vacant spectrum. …”
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Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63 by Kathryn E. King, Linan Ha, Tura Camilli, Wendy C. Weinberg

“…These isoforms can mimic or interfere with one another, and their balance ultimately determines biological outcome in a context-dependent manner. While not frequently mutated, p63, and in particular the ΔNp63 subclass, is commonly overexpressed in human squamous cell cancers. …”
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Phenazine biosynthesis-like domain-containing protein (PBLD) and Cedrelone promote antiviral immune response by activating NF-ĸB by Peili Hou, Hongchao Zhu, Fengyun Chu, Yan Gao, Xiaonan Sun, Fuzhen Zhang, Xiaomeng Wang, Yueyue Feng, Xingyu Li, Yu Liu, Jun Wang, Xiaoyun Wang, Daniel Chang He, Hongmei Wang, Hongbin He

“…Furthermore, the therapeutic potential of Cedrelone lies in its ability to enhance antiviral immunity in primary macrophages and to promote survival and reduce lung tissue damage in HSV-1-infected mice in a PBLD-dependent manner. Consequently, our findings provide a potential combination model that targets PBLD for Cedrelone antiviral drug therapy, potentially paving the way for the development of broad-spectrum antiviral agents.…”
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Resilient routing in ad hoc wireless sensor networks by Tehmina Karamat Khan, Taimur Karamat, Asad Ullah Shah, Umair Aitimad

“…Ad hoc Wireless Sensor Networks (WSNs) are specialized networks comprising a collection of sensor nodes that communicate to perform a specific task or record data in a decentralized manner. A considerable amount of work has been done regarding security, power saving, and other issues related to ad hoc wireless sensor networks, but there have been fewer efforts to improve performance, optimal utilization, and minimize packet loss. …”
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A New Coupled CFD/Neutron Kinetics System for High Fidelity Simulations of LWR Core Phenomena: Proof of Concept by Jorge Pérez Mañes, Victor Hugo Sánchez Espinoza, Sergio Chiva, Robert Stieglitz

“…By applying codes like CFD (computational fluid dynamics) and SP3 (simplified transport) reactor dynamics it is possible to describe the underlying phenomena in a more accurate manner than by the nodal/coarse 1D thermal hydraulic coupled codes. …”
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Novel UHF RFID Near-Field Reader Antenna with Uniform Vertical Electric Field Distribution by Yanbin Chen, Xiaojuan Ren, Jimin Zhao, Xin Chen, Yuan Yao, Junsheng Yu, Xiaodong Chen

“…Third, both antennas are fed in a coaxial manner at the center of the antenna. The simulation and measurement results can show that the proposed three-branch antenna and four-branch antenna achieve good impedance matching in the range of 883–960 MHz and 870–960 MHz, respectively, and achieve uniform distribution of the vertical electric field component in a certain area. …”
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Bayesian Approach for Sequential Probabilistic Back Analysis of Uncertain Geomechanical Parameters and Reliability Updating of Tunneling-Induced Ground Settlements by Cong Li, Shui-Hua Jiang, Jinhui Li, Jinsong Huang

“…The reliability of tunneling-induced ground settlements can be updated in a real-time manner by fully utilizing the time-series monitoring data. …”
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SPATIAL DISTRIBUTION OF SOME MICROELEMENTS IN SOIL IN THE AL-RIFAI DISTRICT OF THE DHI QAR GOVERNORATE by R. T. Al-Badiri, A. R. Jubier, M. S. Oleiwi

“…The horizons of the pedons were described in a basic morphological manner, and samples were collected from each site for laboratory analyses. …”
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Quercetin as a radiosensitizer for enhanced efficacy of radiotherapy in MCF-7 breast cancer cells by Mohammad Banparvar, Hamid Saeidi Saedi, Mona Haddad Zahmatkesh

“…Conclusions: The study's findings demonstrated that quercetin has the ability to increase the sensitivity of MCF-7 breast cancer cells to ionizing radiation in a manner that depends on the dosage.…”
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Extensive Growth of an Anaplastic Meningioma by Hajrullah Ahmeti, Homajoun Maslehaty, Athanasios K. Petridis, Alexandros Doukas, Mehran Mahvash, Harald Barth, H. M. Mehdorn

“…A surgical procedure with the aim of complete tumor resection in a curative manner was not possible. Six months after the first operation, due to a new tumor progression, most extensive tumor resection was performed. …”
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Rapid Sampling of Large Quantities of Interstitial Fluid from Human Skin Using Microneedles and a Vacuum-assisted Skin Patch by Elizabeth Wilkirson, Xue Jiang, Peter Lillehoj

“…The ability to collect ample volumes of ISF in a quick and minimally invasive manner will facilitate the analysis of ISF for biomarker discovery and its use for diagnostic testing.…”
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Akkermansia muciniphila Mediated the Preventive Effect of Disulfiram on Acute Liver Injury via PI3K/Akt Pathway by Ruonan Zhang, Xuewei Sun, Han Lu, Xinrui Zhang, Mingyan Zhang, Xuewen Ji, Xinyi Yu, Chengliang Tang, Zihan Wu, Yinghua Mao, Jin Zhu, Minjun Ji, Zhan Yang

“…Our findings indicate that DSF primarily restores intestinal microbiome balance by modulating the abundance of Akkermansia muciniphila (A. muciniphila), leading to significant alleviation of ALI symptoms in a gut microbiota dependent manner. We also found that A. muciniphila can promote the activation of PI3K/Akt pathway, correct the Bcl‐2/Bax ratio, and further inhibit hepatocyte apoptosis. …”
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Acute Psychological Stress Modulates the Expression of Enzymes Involved in the Kynurenine Pathway throughout Corticolimbic Circuits in Adult Male Rats by Haley A. Vecchiarelli, Chaitanya P. Gandhi, Matthew N. Hill

“…Glucocorticoid hormones and inflammatory mediators, both of which are increased by stress, have been shown to bias tryptophan along the kynurenine pathway and away from serotonin synthesis; however, to date, there is no published data regarding the effects of stress on enzymes regulating the kynurenine pathway in a regional manner throughout the brain. Herein, we examined the effects of an acute psychological stress (120 min restraint) on gene expression patterns of enzymes along the kynurenine pathway over a protracted time-course (1–24 h post-stress termination) within the amygdala, hippocampus, hypothalamus, and medial prefrontal cortex. …”
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Effects of Bamboo Shoot Dietary Fiber on Mechanical Properties, Moisture Distribution, and Microstructure of Frozen Dough by Hua Zhang, Yanyan Zhang, Xintian Wang, Qisen Xiang, Yanhong Bai, Suyun Li, Lixin Yang

“…The result showed that the BSDF could significantly improve the viscoelasticity and extensibility of frozen dough after thawing in a dose-dependent manner. It was significantly improved with the increase in the addition amount of BSDF (P<0.05). …”
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Bounded rational real‐time charging pricing strategy under the traffic‐grid coupling network by Chudi Wang, Shaohua Ma, Zhiyuan Cai, Ning Yan, Qiwei Wang

“…Abstract This study proposes a bounded rational charging guidance strategy based on mental account theory, which guides users to charge in an orderly manner by formulating real‐time charging prices. Firstly, an orderly guidance framework for fast‐charging EVs under the traffic‐grid coupling network is constructed, and the influencing factors of various dimensions when users make charging decisions are analysed. …”
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