Rosiglitazone Alleviates Mechanical Allodynia of Rats with Bone Cancer Pain through the Activation of PPAR-γ to Inhibit the NF-κB/NLRP3 Inflammatory Axis in Spinal Cord Neurons by Jie Fu, Baoxia Zhao, Chaobo Ni, Huadong Ni, Longsheng Xu, Qiuli He, Miao Xu, Chengfei Xu, Ge Luo, Jianjun Zhu, Jiachun Tao, Ming Yao

“…We found that rosiglitazone treatment relieved bone cancer-induced mechanical hyperalgesia in a dose-dependent manner, promoted the expression of peroxisome proliferator-activated receptor-γ (PPAR-γ) in spinal cord neurons, and inhibited the activation of the nuclear factor-kappa B (NF-κB)/nod-like receptor protein 3 (NLRP3) inflammatory axis induced by BCP. …”
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Bulk Viscous Bianchi Type VI0 Cosmological Model in the Self-creation Theory of Gravitation and in the General Theory of Relativity by E. A. Hegazy

“…Effect of the viscosity on the entropy of the universe is given by a composition of the second law of thermodynamics with the the energy momentum tensor Tji with bulk viscous term in a conservative manner. We obtained a formula for calculation the entropy of the universe in term of the viscosity and used it to study and compare the Entropy, Enthalpy, Gibbs energy and Helmholtz energy of the universe in the presence of viscosity term in the self-creation theory of gravitation and in the general theory of relativity. …”
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Cross-scale covariance for material property prediction by Benjamin A. Jasperson, Ilia Nikiforov, Amit Samanta, Fei Zhou, Ellad B. Tadmor, Vincenzo Lordi, Vasily V. Bulatov

“…All simulations use the same 178 IPs. In a manner similar to statistical studies in public health, we analyze correlations of strength with indicators, identify the best predictor properties, and build a cross-scale “strength-on-predictors” regression model. …”
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Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies by Laura Mandolesi, Francesca Gelfo, Laura Serra, Simone Montuori, Arianna Polverino, Giuseppe Curcio, Giuseppe Sorrentino

“…We are made in a certain manner and what we do acts on our brain. In fact, our genetic basis can be modulated, modified, and changed by our experiences such as education and life events; daily, by sleep schedules and habits; or also by dietary elements. …”
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A Multitask Multiview Neural Network for End-to-End Aspect-Based Sentiment Analysis by Yong Bie, Yan Yang

“…Existing methods deal with both subtasks one by one in a pipeline manner, in which there lies some problems in performance and real application. …”
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Levetiracetam Ameliorates L-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats Inducing Critical Molecular Changes in the Striatum by Huan Du, Shuke Nie, Guiqin Chen, Kai Ma, Yan Xu, Zhentao Zhang, Stella M. Papa, Xuebing Cao

“…Following chronic administration of L-DOPA (12 mg/kg, twice daily for 14 days), rats developed abnormal involuntary movements (AIMs), but co-administration of levetiracetam (15, 30, and 60 mg/kg) with equivalent L-DOPA dosing significantly reduced AIMs scores in a dose dependent manner. The effects of levetiracetam were associated with changes in striatal expression of ΔFosB, phosphorylated extracellular signal-regulated kinases 1 and 2 (p-ERK1/2), and phosphorylated cAMP-regulated phosphoprotein of 32 kDa (p-DARPP-32). …”
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Clinical Feature of Men Who Benefit from Dose Escalation of Naftopidil for Lower Urinary Tract Symptoms: A Prospective Study by Takaki Mizusawa, Noboru Hara, Kenji Obara, Etsuko Isahaya, Yuki Nakagawa, Kota Takahashi

“…The 75 mg group showed improvement in the total IPSS and QOL score in a dose-dependent manner (at 4 weeks: 𝑃<.001, at 4 weeks versus 8 weeks: 𝑃<.05). …”
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Collisions of Animals With Road Vehicles in Traffic in the Czech Republic in Connection with Tourism – Analyses of Causes and Prevention by Petr Šmíd, Emílie Pecharová, Dagmar Škodová Parmová

“…The development of the number of accidents in individual periods and the scope of damage in relation to the collisions are analysed in such a manner as to allow for comparison of any financial resources spent on prevention with damage that has already occurred. …”
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β-Glucan-modified nanoparticles with different particle sizes exhibit different lymphatic targeting efficiencies and adjuvant effects by Wen Guo, Xinyue Zhang, Long Wan, Zhiqi Wang, Meiqi Han, Ziwei Yan, Jia Li, Ruizhu Deng, Shenglong Li, Yuling Mao, Siling Wang

“…Particle size and surface properties are crucial for lymphatic drainage (LN), dendritic cell (DC) uptake, DC maturation, and antigen cross-presentation induced by nanovaccine injection, which lead to an effective cell-mediated immune response. However, the manner in which the particle size and surface properties of vaccine carriers such as mesoporous silica nanoparticles (MSNs) affect this immune response is unknown. …”
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Effects of Ozone Treatments on the Physicochemical Changes of Myofibrillar Proteins from Silver Carp (Hypophthalmichthys molitrix) during Frozen Storage by Rongrong Zhang, Shanbai Xiong, Juan You, Yang Hu, Ru Liu, Tao Yin

“…Physicochemical changes of myofibrillar proteins from silver carp surimi during frozen storage as affected by two manners of ozone treatments were investigated. For preparation of surimi treated with ozone, ozone water (8 mg/L) was used in either the first (To1) or the second (To2) cycle of rinsing. …”
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Enantioselective Heck/Tsuji−Trost reaction of flexible vinylic halides with 1,3-dienes by Li-Zhi Zhang, Pei-Chao Zhang, Qian Wang, Min Zhou, Junliang Zhang

“…Specifically, the Heck insertion as stereodetermining step to form ƞ3 allyl palladium complex and in situ trapping with nucleophiles enable efficient Heck/etherification in a formal (4 + 2) cycloaddition manner. Engineering the Sadphos bearing androgynous non-C2-symmetric chiral sulfinamide phosphine ligands are vital component in achieving excellent catalytic reactivity and enantioselectivity. …”
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Investigating the Organization of Zakat in Iran with Emphasis on Zakat Law and Regulations by Hosin Hasanzadeh Sarvestani, Alireza Etemadifar

“…In this study, using the meta-synthesis method, the challenges of the Zakat Organization were extracted through the analysis of the works of researchers and were examined in a comparative manner with the provisions of the Zakat Law and Regulations. …”
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Pilot Contamination Mitigation via a Novel Time-Shift Pilot Scheme in Large-Scale Multicell Multiuser MIMO Systems by Zhangkai Luo, Huali Wang, Wanghan Lv

“…Moreover, users within a cell transmit the same pilot sequence in a time-shift manner during the channel estimation stage and in this way all user terminals’ channel state information can be estimated without contamination. …”
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β-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced Hyperglycemia by Kristoffer L. Egerod, Chunyu Jin, Pia Steen Petersen, Nils Wierup, Frank Sundler, Birgitte Holst, Thue W. Schwartz

“…It is concluded that GPR39 functions in a β-cell protective manner and it is suggested that it is involved in some of the beneficial, β-cell protective effects observed for Zn++ and that GPR39 may be a target for antidiabetic drug intervention.…”
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A Critique on the Book Managerial Movements in Public Sector (Past, Present and Future) by Mehdi Golverdi

“…In this article, the attempt was to review the book in a descriptive-analytical manner, by mentioning the evidence and documents. …”
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Pathology of the Arabic Language Curriculum A Case Study: Farhangian University by Hedayatollah Taghizadeh

“…The research information was obtained through documentary studies and by using quantitative and descriptive methods and using the researcher-made questionnaire in a statistical population consisting of professors of Farhangian University of Tehran, in a purposeful and comprehensive manner. The results show that the most important quantitative changes have been the reduction of the share of specialized units from 93 units to 54 units and the increase of the share of educational courses. …”
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The effect of a hypocycloid irregularity on torsional surface waves in a multilayer system by Saha Anup, Das Sandip Kumar

“…It is assumed that the directional rigidities, density and initial stress vary in the upper and lower semi-infinite spaces in an exponential and hyperbolic manner, respectively. A closed form for the torsional wave dispersion equation is presented. …”
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Small-molecule-induced ERBB4 activation to treat heart failure by Julie M. T. Cools, Bo K. Goovaerts, Eline Feyen, Siel Van den Bogaert, Yile Fu, Céline Civati, Jens Van fraeyenhove, Michiel R. L. Tubeeckx, Jasper Ott, Long Nguyen, Eike M. Wülfers, Benji Van Berlo, Antoine A. F. De Vries, Nele Vandersickel, Daniël A. Pijnappels, Dominique Audenaert, H. Llewelyn Roderick, Hans De Winter, Gilles W. De Keulenaer, Vincent F. M. Segers

“…EF-1 reduces cell death and hypertrophy in cardiomyocytes and decreases collagen production in cardiac fibroblasts in an ERBB4-dependent manner. In wild-type mice, EF-1 inhibits angiotensin-II-induced fibrosis in males and females and reduces heart damage caused by doxorubicin and myocardial infarction in females, but not in Erbb4-null mice. …”
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A Computer Vision-Based Framework for Snow Removal Operation Routing by Mohamed Karaa, Hakim Ghazzai, Yehia Massoud, Lokman Sboui

“…For unmonitored roads, we use the Graph Convolutional Network architecture to predict parameters in a semi-supervised manner. Following that, we assign priority weights to all graph edges as a function of image-based attributes and road categories. …”
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Differential Dynamics of ATR-Mediated Checkpoint Regulators by Daniël O. Warmerdam, Roland Kanaar, Veronique A. J. Smits

“…Interestingly, ATRIP directly associated with locally induced UV damage, whereas Rad9 bound in a cooperative manner, which can be explained by the Rad17-dependent loading of Rad9 onto damaged chromatin. …”
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