Fractional tackles: leveraging player tracking data for within-play tackling evaluation in American football by Quang Nguyen, Ruitong Jiang, Meg Ellingwood, Ronald Yurko

“…Using player tracking data, we present a novel framework for assessing tackling contribution in a continuous and objective manner. Our approach first identifies when a defender is in a “contact window” of the ball-carrier during a play, before assigning value to each window and the players involved. …”
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The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity by Tamara M Sirey, Kenny Roberts, Wilfried Haerty, Oscar Bedoya-Reina, Sebastian Rogatti-Granados, Jennifer Y Tan, Nick Li, Lisa C Heather, Roderick N Carter, Sarah Cooper, Andrew J Finch, Jimi Wills, Nicholas M Morton, Ana Claudia Marques, Chris P Ponting

“…Here we show that Cerox1, an unusually abundant cytoplasmic long noncoding RNA (lncRNA), modulates the levels of mitochondrial complex I subunit transcripts in a manner that requires binding to microRNA-488-3p. Increased abundance of Cerox1 cooperatively elevates complex I subunit protein abundance and enzymatic activity, decreases reactive oxygen species production, and protects against the complex I inhibitor rotenone. …”
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The stepwise decrease of 4+ year ice extent and its linked survivability since around 2007 by Qi Shan, Ke Fan, Jiping Liu

“…We demonstrate that the decrease of 4+ year ice is controlled by the decrease of its linked survivability in a non-linear manner, signifying small alterations in the survivability can result in relatively large changes in the extent of 4+ year ice. …”
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A multiobjective continuation method to compute the regularization path of deep neural networks by Augustina Chidinma Amakor, Konstantin Sonntag, Sebastian Peitz

“…To overcome this limitation, we present an algorithm that allows for the approximation of the entire Pareto front for the above-mentioned objectives in a very efficient manner for high-dimensional DNNs with millions of parameters. …”
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Identification and structure-guided development of triazole urea-based selective antagonists of Arabidopsis karrikin signaling by Jianwen Wang, Ikuo Takahashi, Ko Kikuzato, Toshihiko Sakai, Zhangliang Zhu, Kai Jiang, Hidemitsu Nakamura, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa, Tadao Asami

“…We further elucidate the antagonistic, KAI2 binding mechanism of KK181N1, showing that KK181N1 binds to the catalytic pockets of KAI2 in a non-covalent binding manner. Our experiments also demonstrate the binding affinity of triazole urea compounds are regulated by the structured water molecule networks. …”
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Spike frequency adaptation in primate lateral prefrontal cortex neurons results from interplay between intrinsic properties and circuit dynamics by Nils A. Koch, Benjamin W. Corrigan, Michael Feyerabend, Roberto A. Gulli, Michelle S. Jimenez-Sosa, Mohamad Abbass, Julia K. Sunstrum, Sara Matovic, Megan Roussy, Rogelio Luna, Samuel A. Mestern, Borna Mahmoudian, Susheel Vijayraghavan, Hiroyuki Igarashi, Kartik S. Pradeepan, William J. Assis, J. Andrew Pruszynski, Shreejoy Tripathy, Jochen F. Staiger, Guillermo Gonzalez-Burgos, Andreas Neef, Stefan Treue, Stefan Everling, Wataru Inoue, Anmar Khadra, Julio C. Martinez-Trujillo

“…Developing a data-driven hybrid circuit model comprising NS model neurons receiving BS input reveals that NS model neurons exhibit longer SFA than observed in vivo; however, adding feedforward inhibition corrects this in a manner dependent on I-SFA. Identification of this circuit motif shaping E-SFA in LPFC highlights the roles of both intrinsic and network mechanisms in neural activity underlying behavior.…”
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The Analysis of the Concept of Gender in the Drama “Drought and Lie” through the Discourse-Historical Approach of Ruth Wodak by Halimeh Enayat, Marzieh Askari

“…The purpose of this research is to study the concept of gender in the aforementioned text in order to identify the manner in which this concept is generated or perpetuated within the context of the social conditions of Iran in the 2000s. …”
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Easy and Complicated" Feature in the Tales of Sa’di'sGolestan; a Morphological Explanation by Sare Zirak, Hadis Azizian Gilan

“…The absence of problem-solving and its mechanisms makes simplified the structure of the tales. The manner of the distribution of the characters, functions, and initial situations, in the level beyond mere individual narratives, has provided a comprehensive coherence in the text, which explain how Saa’di create a new version of rhetoric in the way of "how to say". …”
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Effects of vitamin C on cardiovascular oxidative stress induced by hypothyroidism in neonatal and juvenile rats by Farimah Beheshti, Reza Mohebbati, Mahmoud Hosseini, Saeed Niazmand, Masomeh Mirzaei, Mahdiyeh Hedayati-Moghadam, Maryam Paseban

“…The experimental treatments continued for the first eight weeks of the offspring’s life, following the lactation period, and the offspring were treated in the same manner. At the end of the study, the rats were sacrificed, and serum, aortic, and cardiac tissues were collected for antioxidant evaluation. …”
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Power of communication as a factor of human resource management by Bajić Zoran, Karavidić Marija

“…Therefore, successful managers must be familiar with the communication skills - the advantages and disadvantages of all types of communication, communication barriers and the manner of their elimination. One of the key roles of managers in the modeling of business relationships and relations is the communication management.…”
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Discovery of new topological insulators and semimetals using deep generative models by Tao Hong, Taikang Chen, Dalong Jin, Yu Zhu, Heng Gao, Kun Zhao, Tongyi Zhang, Wei Ren, Guixin Cao

“…In this study, we propose an efficient inverse design method CTMT (CTMT: CDVAE, Topogivity, interatomic potentials (IAPs) as realized in M3GNet, and TQC) utilizing deep generative machine learning models to discover novel topological insulators and semimetals in a much-fast and low-cost manner. This method covers the entire process of new crystal structure generation, heuristic rule screening, fast stability estimation, and topology type diagnosis, resulting in 4 topological insulators and 16 topological semimetals. …”
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Tumor Necrosis Factor Alpha Mediates GABAA Receptor Trafficking to the Plasma Membrane of Spinal Cord Neurons In Vivo by Ellen D. Stück, Randolph N. Christensen, J. Russell Huie, C. Amy Tovar, Brandon A. Miller, Yvette S. Nout, Jacqueline C. Bresnahan, Michael S. Beattie, Adam R. Ferguson

“…GABAAR protein levels in membrane fractions of TNFα and vehicle-treated subjects were not significantly different by Western Blot, yet high-resolution quantitative confocal imaging revealed that TNFα induces GABAAR trafficking to synapses in a dose-dependent manner by 60 min. TNFα-mediated GABAAR trafficking represents a novel target for CNS excitotoxicity.…”
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Investigation of the dose and structure effects of lipid oxidation products aldehydes on the generation of heterocyclic amines: A case study of 2-amino-1-methyl-6-phenylimidazo [4,... by Mantong Zhao, Zhongyuan Liu, Mengyin Zha, Ying Sun, Haohao Shi, Xueying Zhang, Chuan Li, Guanghua Xia

“…During pan-frying, massive aldehydes were generated in a time-dependent manner with acrolein, propanal, hexanal, 4-hydroxy-nonenal (HNE), and 2,4-decadienal (DDE) as the abundant species. …”
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Experimental demonstration of complete quantum information masking and generalization of quantum secret sharing by Zhi-Feng Liu, Wei-Min Shang, Jia-Min Xu, Zi-Mo Cheng, Wen-Zheng Zhu, Hao Li, Pei Wan, Shu-Tian Xue, Yan-Chao Lou, Chao Chen, Zhi-Cheng Ren, He Lu, Fu-Lin Zhang, Jing-Ling Chen, Xi-Lin Wang, Hui-Tian Wang

“…Furthermore, we implement QSS between six players by expanding the 4-qubit state to a 6-qubit state entangled in hybrid manner, in which we observe an average fidelity 0.85 ± 0.03 of the recovered states. …”
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GPX modulation promotes regenerative axonal fusion and functional recovery after injury through PSR-1 condensation by Su-Hyuk Ko, Kyung-Ah Cho, Xin Li, Qitao Ran, Zhijie Liu, Lizhen Chen

“…We discover that ferroptosis signaling can promote axonal fusion and functional recovery in C. elegans in a dose-sensitive manner. Ferroptosis-induced lipid peroxidation enhances injury-triggered phosphatidylserine exposure (PS) to promote axonal fusion through PS receptor (PSR-1) and EFF-1 fusogen. …”
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Battery Energy Forecasting in Electric Vehicle Using Deep Residual Neural Network by Mohamad Reda A. Refaai, Jyothilal Nayak Bharothu, T. V. V. Pavan Kumar, Chodagam Srinivas, M. Sudhakar, Anirudh Bhowmick

“…In the recent decade, it is possible to use electric vehicles in a safe, cost-effective, and environmentally friendly manner, but only if accurate and trustworthy state parameter predictions are produced prior to their disposal. …”
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Obstructive Sleep Apnea Monocytes Exhibit High Levels of Vascular Endothelial Growth Factor Secretion, Augmenting Tumor Progression by Carolina Cubillos-Zapata, Enrique Hernández-Jiménez, José Avendaño-Ortiz, Victor Toledano, Anibal Varela-Serrano, Isabel Fernández-Navarro, Raquel Casitas, Carlos Carpio, Luis A. Aguirre, Francisco García-Río, Eduardo López-Collazo

“…Moreover, these cells under IH polarize toward a tumor-promoting phenotype in a HIF1α-dependent manner and influence tumor growth via vascular endothelial growth factor (VEGF). …”
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Integration of National Chemical Hazards Monitoring, Total Diet Study, and Human Biomonitoring Programmes for Food Safety Exposure Assessment in Singapore by Angela Li, Jun Cheng Er, Wei Ching Khor, Mei Hui Liu, Valerie Sin, Sheot Harn Chan, Kyaw Thu Aung

“…Food and food system innovation is a key strategy towards feeding the world in a more sustainable and climate-resilient manner. This paper highlights the use of a science-based risk assessment and management in Singapore’s food safety system, specifically in the integration of exposure assessment approaches to support evidence-based food safety risk analysis and decision-making. …”
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Small-Molecule Hormones: Molecular Mechanisms of Action by Monika Puzianowska-Kuznicka, Eliza Pawlik-Pachucka, Magdalena Owczarz, Monika Budzińska, Jacek Polosak

“…Nuclear hormone receptors interact with coactivators, corepressors, basal transcription factors, and other transcription factors in order to modulate the activity of target genes in a manner that is dependent on tissue, age and developmental and pathophysiological states. …”
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Effect of infill pattern on the microstructure and properties of copper processed through metal fused filament fabrication technique by Salethkumar Jasper, Manickam Ravichandran, Chander Prakash, N. Radhika

“…Metal fused filament fabrication (MFFF) is one of the promising AM method for creating metallic components in an accessible and affordable manner. This work reports the how infill patterns affect the densification, microstructural integrity, and functional performance of copper parts fabricated using MFFF. …”
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