In vitro triazophos suppresses innate and cell-mediated immune responses of lymphoid organs in snakehead fish, Channa punctatus by Rakesh Kumar Chandra, Ajay Kumar Bhardwaj, Neha Gupta, Devendra Kumar Patel, Manish Kumar Tripathi

“…Additionally, triazophos suppressed the phagocytosis by lymphoid organ cells in a dose-dependent manner. Residual pesticides present in aquatic bodies pose a critical problem and understanding their role in modulating the physiological responses of aquatic organisms is essential. …”
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Cytosolic DNA composition is determined by genomic instability mechanism and regulates dendritic cell-mediated anti-tumor immunity by Shayla R. Mosley, Angie Chen, David N.W. Doell, Siwon Choi, Courtney Mowat, Felix Meier-Stephenson, Vanessa Meier-Stephenson, Kristi Baker

“…Sequencing indicates that MSI cyDNA is enriched in microsatellites, which, upon DC uptake, induce anti-tumor immunity in a manner consistent with clinical MSI CRCs. DNA-damaging therapies also modulate cyDNA stimulation capacity, with radiation inducing larger cyDNA sizes and increased mitochondrial DNA content. …”
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Identification of nine mammal monosaccharides by solid-state nanopores by Yunze Sun, Zhuang Mi, Xiaoyu Chen, Jian-Jun Li, Jun Lu, Xinyan Shan, Xinghua Lu, Yuguang Du

“…Inspired by this, it is potential to sequence glycans in the similar manner. Herein, SiNx nanopores were used to identify nine common monosaccharides in mammals. …”
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Engineering a Biocompatible Scaffold with Either Micrometre or Nanometre Scale Surface Topography for Promoting Protein Adsorption and Cellular Response by Xuan Le, Gérrard Eddy Jai Poinern, Nurshahidah Ali, Cassandra M. Berry, Derek Fawcett

“…It is believed that by engineering a well-defined nanometre scale surface topography, it should be possible to induce appropriate surface signals that can be used to manipulate cell function in a similar manner to the extracellular matrix. Therefore, there is a need to investigate, understand, and ultimately have the ability to produce tailor-made nanometre scale surface topographies with suitable surface chemistry to promote favourable biological interactions similar to those of the extracellular matrix. …”
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Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders by I. De Toma, L. Manubens Gil, S. Ossowski, M. Dierssen

“…Epigenetic treatments act in a context specific manner, targeting different regions based on cell and state specific chromatin accessibility, facilitating the establishment of the lost balance. …”
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The survival of B cells is compromised in kidney disease by Doureradjou Peroumal, Chetan V. Jawale, Wonseok Choi, Hossein Rahimi, Danielle Antos, De-dong Li, Shuxia Wang, Godhev K. Manakkat Vijay, Isha Mehta, Raymond West, Muthusamy Thangaraju, Thomas D. Nolin, Jishnu Das, John F. Alcorn, Partha S. Biswas

“…Uremic toxin hippuric acid drives loss of mitochondrial membrane potential, leading to increased apoptosis of GC B cells in a G-protein–coupled receptor 109A dependent manner. Finally, GC B cells and antibody titer are diminished in mice with kidney disease following influenza virus infection, a major cause of mortality in individuals with renal disorders. …”
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Compressive Fracture of Brittle Geomaterial: Fractal Features of Compression-Induced Fracture Surfaces and Failure Mechanism by L. Ren, L. Z. Xie, C. B. Li, J. Wang

“…No remarkable differences between the fractal dimensions of the compression-induced and tension-induced fracture surfaces may indicate that compressive fracture may occur, at least on the investigative scale of this work, in a similar manner to tension fracture.…”
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PRELIMINARY STUDY ON DRIED GREEN BOTTLE FLY LUCILIA CAESAR “RESOURCE SAVING/DIVERSIFICATION” by Людмила Анатольевна Надточий, Кифлом Негаси Тсиге, Мохамед Саид Булькран, Алёна Владиславовна Проскура, Мариам Башировна Мурадова

“…Based on the proximate analyses, the crude protein content of ground green bottle fly larvae paste had significantly increased from 45.20 to 64.95 % after defatting. In similar manner, the ash and moisture content of the samples also increased to 7.10 and 4.95 % respectively. …”
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The Role of Protein Modifications of T-Bet in Cytokine Production and Differentiation of T Helper Cells by Sera Oh, Eun Sook Hwang

“…T-Bet simultaneously modulates IL-2 and Th2 cytokines in an IFN-γ-independent manner, resulting in an attenuation of Th2 cell development. …”
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Structure Characterization and Antioxidant Activity of a Novel Polysaccharide from <i>Bacillus natto</i> Fermented Millet Bran by Hanzhuo Zhang, Xia Fan, Wenjie Zhao, Fanqiang Meng, Fengxia Lu, Zhaoxin Lu, Haizhen Zhao

“…In addition, the antioxidant assays indicated that FMBP-1 possessed certain capacities for scavenging free radicals and reducing power, and this was in a concentration-dependent manner. This research will provide fundamental data regarding the structure–activity relationship of millet bran polysaccharides and provide a theoretical foundation for the high-value utilization of millet bran within the food and pharmaceutical industries.…”
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Expert advice from ResearchMatch volunteers: Recruitment Innovation Center use cases and innovation by Maeve Tischbein, Sarah K. Cook, Cathy Shyr, Katelyn Benhoff, Amna Baig, Kaysi Quarles, Leslie R. Boone, Loretta M. Byrne, Mariela Rodriguez, Terri Edwards, Consuelo H. Wilkins, Paul A. Harris

“…For this to occur, streamlined mechanisms are needed to connect the populations potentially impacted by a given study or health topic with research teams in order to inform trial design in a meaningful and timely manner. To address this need, we developed an innovative mechanism called the “ResearchMatch Expert Advice Tool” that quickly obtains volunteer perspectives from populations with specific health conditions or lived experiences using the national recruitment registry, ResearchMatch. …”
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Orthodontic retainers: are they all the same? by Telma Martins de ARAUJO, Paula Paes FERREIRA, Izabelle Alice Pinheiro Barros LISBOA, Carlos Jorge VOGEL, Carolina Ribeiro STARLING

“…The retention protocol must be performed in an individualized and planned manner, taking the initial dental positions as a reference. …”
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A Multi-granularity Decomposition Mechanism of Complex Tasks Based on Density Peaks by Ziling Pang, Guoyin Wang, Jie Yang

“…There are many algorithms for solving complex problems in supervised manner. However, unsupervised tasks are more common in real scenarios. …”
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Spatial-temporal initialization dilemma: towards realistic visual tracking by Chang Liu, Yongsheng Yuan, Xin Chen, Huchuan Lu, Dong Wang

“…We summarize the aforementioned phenomenon by comparing differences of the initialization manners in existing tracking benchmarks and in real-world applications. …”
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Adrenal Rest Tumor of the Liver Preoperatively Diagnosed as Hepatocellular Carcinoma by Megumu Enjoji, Katsuya Sanada, Ryota Seki, Takashi Ito, Masato Maeda

“…Microscopic findings showed that the tumor was composed of pale cells, and tumor cells were aligned in alveolar or fascicular arrangements in a similar manner to features of adrenocortical tissue. Immunohistochemically, the tumor expressed synaptophysin and CD56. …”
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AGE/RAGE-Induced EMP Release via the NOX-Derived ROS Pathway by Ying-Hua Chen, Zhang-Wei Chen, Hong-Mei Li, Xin-Feng Yan, Bo Feng

“…The number of EMPs was significantly increased in HUVECs stimulated by AGEs in a dose-dependent manner. In addition, receptors for AGEs (RAGE), NAD(P)H oxidase (NOX), and reactive oxygen species (ROS) were increased by AGEs as compared to the control group. …”
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Paeoniflorin inhibits the growth of bladder carcinoma via deactivation of STAT3 by Yang Jianhui, Ren Yu, Lou Zhong-Guan, Wan Xue, Weng Guo-Bin, Cen Dong

“…The results showed that Pae inhibited proliferation of human BCa cell lines in a concentration- and time-dependent manner. Pae and cisplatin (Cis) synergistically inhibited the growth of tumours in RT4-bearing mice. …”
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Multi-assay assessment of cytotoxicity reveals multiple mechanisms of action in 3D microtissues by Ahbid Zein-Sabatto, Katerina St. Angelo, Samantha J. Madnick, Diane Hoffman-Kim, Jeffrey R. Morgan, Jonghwan Lee

“…Overall, the proposed approach provides a unique opportunity to analyze data from multiple assays in a holistic manner to improve the predictive power of drug screening and toxicology studies.…”
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Examining inclusivity: the use of AI and diverse populations in health and social care: a systematic review by John Gabriel O. Marko, Ciprian Daniel Neagu, P. B. Anand

“…Conclusion AI development practices, legal frameworks, and policies must be reformulated to ensure that AI is applied in an equitable manner. A holistic approach must be used to address disparities, enforce effective regulations, safeguard privacy, promote inclusion and equity, and emphasize rigorous validation.…”
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Improved Clonal Selection Algorithm Based on Biological Forgetting Mechanism by Chao Yang, Bing-qiu Chen, Lin Jia, Hai-yang Wen

“…This part of inactive antibody forms a “black hole” of the antibody set, which is difficult to remove and update in a timely manner, thus affecting the speed at which the algorithm approximates the optimal solution. …”
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