Inflammatory Bowel Diseases: When Natural Friends Turn into Enemies—The Importance of CpG Motifs of Bacterial DNA in Intestinal Homeostasis and Chronic Intestinal Inflammation by Florian Obermeier, Claudia Hofmann, Werner Falk

“…In contrast bacterial DNA essentially contributes to the perpetuation of an already established chronic intestinal inflammation in a Toll-like receptor (TLR)9-dependent manner. This dichotomic action may be explained by a different activation status of essential regulators of TLR signaling like Glycogen synthase kinase 3-𝛽 (GSK3-𝛽) depending on the pre-activation status of the intestinal immune system. …”
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'n Narratiewe teologiese verkenning van negatiewe koronêre vatomleidingsoperasieuitkomste: 'n chirurgiese hermeneutiek by M. J. Swart, G. J. van Zyl, J. A. van den Berg

“…Bearing physiological barriers and lifestyles in mind, as well as God’s involvement, the patient and surgeon can in a new manner reflect on possible negative outcomes following operative procedures. …”
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Intramuscular (Infiltrating) Lipoma of the Floor of the Mouth by Ben-Zion Joshua, Lipa Bodner, Ruthy Shaco-Levy

“…Histopathologically, the lesion was composed of mature adipose tissue that infiltrated the muscle in a diffuse manner. No lipoblasts, atypical cells, or high mitotic index were found. …”
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An Efficient and Self-Adapted Approach to the Sharpening of Color Images by Lih-Jen Kau, Tien-Lin Lee

“…The increment or decrement magnitude that is to be added to those edge pixels is determined in an adaptive manner based on global statistics of the image and local statistics of the pixel to be sharpened. …”
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Beneficial effects of the fructus Sophorae extract on experimentally induced osteoporosis in New Zealand white rabbits by CHAKULESKA LIDIJA, SHKONDROV ALEKSANDAR, POPOV GEORGI, ZLATEVA-PANAYOTOVA NADYA, PETROVA RENETA, ATANASOVA MARIYANA, KRASTEVA ILINA, DOYTCHINOVA IRINI, SIMEONOVA RUMYANA

“…FSE recovered most of the affected parameters in bones in a manner similar to zoledronic acid (ZA) used as a positive control. …”
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Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons by Se-In Lee, Heejin Lim, Na Yeon Kim, Jichang Yu, Joonho Cho, Hyein Lee, Dae Won Moon, Jinsoo Seo

“…In this study, we developed a protocol for imaging APP on lipid rafts using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and found that astrocyte ApoE4 contributes to an increase in APP localization on lipid rafts, subsequently elevating Aβ42 synthesis in a clathrin-independent manner in neurons.…”
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Indoxyl Sulfate-Induced Oxidative Stress, Mitochondrial Dysfunction, and Impaired Biogenesis Are Partly Protected by Vitamin C and N-Acetylcysteine by Wen-Chin Lee, Lung-Chih Li, Jin-Bor Chen, Hsueh-Wei Chang

“…In addition, we used flow cytometry to demonstrate that the level of reactive oxygen species increased in a dose-dependent manner after treatment with IS. High doses of IS also corresponded to increased mitochondrial depolarization and decreased mitochondrial DNA copy number and mitochondrial mass. …”
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Cognitive strategies for UAV trajectory optimization: Ensuring safety and energy efficiency in real-world scenarios by Mushtaq Muhammad Umer, Hein Venter, Owais Muhammad, Tamoor Shafique, Fuad A. Awwad, Emad A.A. Ismail

“…The data and performance metrics, show the system operated in a safe and energy efficient manner. This work provides a unified framework for UAV trajectory planning that guarantees a trade-off between safety and energy efficiency.…”
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Program of functional instruction in reading comprehension of poems in elementary school students by Néstor Miguel Velarde Corrales, Aldo Bazán-Ramírez

“…A prior evaluation of the group showed that 28 of the 30 students had a low level of reading comprehension, therefore, it was formed in a random manner, a group of eleven students who took a training course for reading comprehension, which consisted of six sessions. …”
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Odour generalisation and detection dog training by Lyn Caldicott, Thomas W. Pike, Helen E. Zulch, Daniel S. Mills, Fiona J. Williams, Kevin R. Elliker, Bethany Hutchings, Anna Wilkinson

“…Generalisation, the tendency to respond in the same manner to stimuli which are different – but similar to – a conditioned stimulus, is therefore a crucial requirement for working detection dogs. …”
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A membrane-targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina by Gaia Ziraldo, Sara Cupini, Valentina Sesti, Emanuela Delfino, Guglielmo Lanzani, Chiara Bertarelli, Fabio Benfenati, Stefano Di Marco

“…Here, we show that Ziapin2, a membrane photoswitch that modulates neuronal capacitance and excitability in a light-dependent manner, is capable of reinstating, in mouse and rat genetic models of photoreceptor degeneration, brisk and sluggish ON, OFF, and ON-OFF responses in retinal ganglion cells evoked by full-field stimuli, with reactivation of their excitatory and inhibitory conductances. …”
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Preparation, Physicochemical Characterization, and Microrobotics Applications of Polyvinyl Chloride- (PVC-) Based PANI/PEDOT: PSS/ZrP Composite Cation-Exchange Membrane by Mohd Imran Ahamed, Inamuddin, Abdullah M. Asiri, Mohammad Luqman, Lutfullah

“…The outcomes demonstrated that the manufactured ionomeric membrane could produce generative strengths (tip powers), and consequently create good displacement. In this manner, the proposed ionomeric membrane was found proper for bending movement actuator that will give a successful and promising stage for smaller-scale mechanical applications.…”
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Intelligent Controllers for Multirobot Competitive and Dynamic Tracking by Mei Liu, Shuai Li, Xiaodi Li, Long Jin, Chenfu Yi, Zhiguan Huang

“…Finally, illustrative examples are provided and analyzed to substantiate the efficacy of the proposed models for tracking moving target in a competition manner with all-to-all communications and limited communications.…”
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The neoliberal roots of modern vaccine hesitancy by Chris Sanders, Kristin Burnett

“…Understanding the socio-political meanings that lay people assign to vaccines and the manner in which they communicate these concerns via media is essential for public health practitioners to consider when formulating immunization policy and education praxis. …”
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Numerical Simulation for a Three-Dimensional Air Pollution Measurement Model in a Heavy Traffic Area under the Bangkok Sky Train Platform by Kewalee Suebyat, Nopparat Pochai

“…The simulation is also considered in averaged and moving pollutant sources due to manner vehicle emission. The proposed approximated air pollutant concentration indicators can be replaced by user required gaseous pollutants indices such as NOx, SO2, CO, and PM2.5.…”
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Metformin Suppressed CXCL8 Expression and Cell Migration in HEK293/TLR4 Cell Line by Zhihui Xiao, Wenjun Wu, Vladimir Poltoratsky

“…Our data indicated that metformin suppressed LPS-induced CXCL8 expression in a dose-dependent manner through inhibiting NF-κB, but not AP-1 and C/EBP, activities under the conditions we used. …”
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Accidental Oral Injuries by Electric Toothbrush: A Report of Three Cases by Miki Yamada, Shunsuke Hino, Satoshi Nakamura, Yosuke Iijima, Takahiro Kaneko, Norio Horie

“…Electric toothbrushes can cause oral penetrating injuries and infections in the same manner as manual toothbrushes. Prevention of oral trauma requires familiarity with the form and function of electric toothbrushes. …”
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LPA Promotes T Cell Recruitment through Synthesis of CXCL13 by Weili Hui, Chenqi Zhao, Sylvain G. Bourgoin

“…Here we report in a murine air pouch model of inflammation that LPA induced CXCL13 secretion in a time-dependent manner and with exacerbation of the response when LPA was administered after a pretreatment with TNF-α, a key inflammatory cytokine. …”
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Partial Storage Optimization and Load Control Strategy of Cloud Data Centers by Klaithem Al Nuaimi, Nader Mohamed, Mariam Al Nuaimi, Jameela Al-Jaroodi

“…Moreover, performance is also increased since multiple cloud servers will collaborate to provide the data to the cloud clients in a faster manner.…”
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Immunomodulatory effects of inosine pranobex on cytokine production by human lymphocytes by Lasek Witold, Janyst Michał, Wolny Rafał, Zapała Łukasz, Bocian Katarzyna, Drela Nadzieja

“…Surprisingly, production of IL-10 by PHA-stimulated lymphocytes was suppressed by Inos in a dose-dependent manner in both 24-hour and 72-hour cultures. These results shed some light on immunomodulatory properties of Inos and suggest applicability of this agent in patients with a depressed function of the immune system.…”
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