An analysis of the Policy of Increasing the Salaries of Government Employees Based on the Framework of Kingdon's Multiple Streams (Case Study of Budget Law 1401) by Seyyed Mojtaba Shahraeini, Heidar Najafi, Seyyedamir Abbaszade, Mahdi Khosravi, Iman Akbari

“…Consequently, the mechanism and amount of salary increases for government employees, in a fair and proportionate manner, remain a challenging aspect of the interactions between the government, parliament, and other stakeholders. …”
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Rekomendasi Pengembangan Fasilitas Wisata Tugu Pahlawan Surabaya Melalui Visualisasi Dashboard Hasil Klasifikasi Analisis Sentimen Ulasan Pengunjung by Fawwaz Roja Mahardika, Ahmad Afif Supianto, Nanang Yudi Setiawan, Raden Sandra Yuwana, Endang Suryawati

“…However, the managers do not have technology capable of collecting, processing and analyzing all review datas that can produce information in a concise manner. One solution can be done through sentiment analysis at the aspect level of education, facilities, cleanliness, service, and general aspects by presenting information in the form of a dashboard. …”
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Sodium Butyrate: A Multifaceted Modulator in Colorectal Cancer Therapy by Alexandra Laura Mederle, Alexandra Semenescu, George Andrei Drăghici, Cristina Adriana Dehelean, Nicolae-Valentin Vlăduț, Dragoş Vasile Nica

“…All treatments reduced cell viability, confluence, and number in a dose-dependent manner (<i>p</i> < 0.0001). Gene expression revealed dose-related increases in most pro-apoptotic markers (<i>BAX</i>, <i>CASP3</i>, <i>PUMA</i>; <i>p</i> < 0.001), and decreases for the other genes (<i>p</i> < 0.001). …”
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KATALIKYBĖ IR VISUOMENĖ TARPUKARIO LIETUVOJE by Valdas Pruskus

“…Such formal membership, which entitled an individual to call him (herself) a believer, as well as the aesthetical-demonstrative manner of being a member of the Church, expressing itself by almost obligatory participation in all mass religious actions (various arrangements), aiming to manifest the Catholic "acting" and solidarity, did not stimulate a conscious and authentic confession of the faith. …”
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Predicting Iran Cooperative Development Bank's Profit/Loss: Two-stage Collective Learning by Seyed Bagher Fattahi, Seyed Mozafar Mirbargkar, Ebrahim Chirani, Mohammadreza Vatanparast

“…The results of data analysis reveal that the average ratio of the net profit or loss of the bank to its total assets has been computed in a manner that reflects the average profitability of the bank branches over the research period.…”
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Formulating a Blue Ocean Strategy in the Banking Services Industry: Enhancing Customer Satisfaction through Improved Demand Fulfillment and Presenting an Optimal Pattern by Manuchehr Ghanbari, Ali Sabzali Yameqani, Yousef Rabbani, Kobra Sabzali Yamaqani

“…Conducted in an exploratory manner, the research is characterized by a practical orientation and a comparative approach. …”
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Regulation of human papillomavirus E6 oncoprotein function via a novel ubiquitin ligase FBXO4 by Arushi Vats, Luca Braga, Nezka Kavcic, Paola Massimi, Edoardo Schneider, Mauro Giacca, Laimonis A. Laimins, Lawrence Banks

“…Furthermore, our data demonstrate that the combined knockdown of FBXO4 and E6AP not only rescues the protein levels of E6 but also induces high levels of cell death in a p53-dependent manner in the HPV-positive cervical cancer cell line, HeLa. …”
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Mass Casualty Incident Training in Immersive Virtual Reality: Quasi-Experimental Evaluation of Multimethod Performance Indicators by Anke Sabine Baetzner, Yannick Hill, Benjamin Roszipal, Solène Gerwann, Matthias Beutel, Tanja Birrenbach, Markus Karlseder, Stefan Mohr, Gabriel Alexander Salg, Helmut Schrom-Feiertag, Marie Ottilie Frenkel, Cornelia Wrzus

“… BackgroundImmersive virtual reality (iVR) has emerged as a training method to prepare medical first responders (MFRs) for mass casualty incidents (MCIs) and disasters in a resource-efficient, flexible, and safe manner. However, systematic evaluations and validations of potential performance indicators for virtual MCI training are still lacking. …”
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Analisis Strategi Pemasaran Politik Kampanye Kukuh Haryanto Sebagai Calon Legislatif DPRD Kabupaten Wonogiri Dalam Kontestasi Pemilihan Umum Tahun 2024 by Shildamullah Danendra Mukti Ardana, Titin Purwaningsih

“…Data analysis was carried out using the Internet of Things approach and Adman Nursal’s political marketing theory in a descriptive manner. The results reveal that Kukuh Haryanto has had a longstanding interest in politics. …”
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Differential impact of TIM-3 ligands on NK cell function by Xin Zhang, Lazar Vujanovic, Riyue Bao, Robert L Ferris, Tullia C Bruno, Aditi Kulkarni, Hridesh Banerjee, Housaiyin Li, Juncheng Wang, Lawrence P Kane, Pragati Upadhyay, Jennifer L Anderson, Onyedikachi Victor Onyekachi, Lidia M R B Arantes

“…Among the four putative TIM-3 ligands, galectin-9 most consistently suppresses NK cell-mediated cytotoxicity and proliferation through TIM-3 and CD44 signaling, respectively, but promotes IFN-γ release in a TIM-3-dependent manner. Among patients with HNSCC, an elevated intratumoral TIM-3+ NK cell gene signature associates with worse outcomes, specifically in those with human papillomavirus (HPV)+ disease, potentially attributable to higher galectin-9 levels in HPV+ versus HPV− patients.Conclusions Our findings underscore the complex functional impact of TIM-3 ligand signaling, which is consistent with recent clinical trials suggesting that targeting TIM-3 alone is suboptimal as an immunotherapeutic approach for treating malignancies.…”
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KATALIKYBĖ IR VISUOMENĖ TARPUKARIO LIETUVOJE by Valdas Pruskus

“…Such formal membership, which entitled an individual to call him (herself) a believer, as well as the aesthetical-demonstrative manner of being a member of the Church, expressing itself by almost obligatory participation in all mass religious actions (various arrangements), aiming to manifest the Catholic "acting" and solidarity, did not stimulate a conscious and authentic confession of the faith. …”
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Factors influencing preformed metal crowns and prefabricated zirconia crowns by Shuman Deng, Weiwei Dou, Ying Chen, Zhixiao Chen, Ning Song, Qi Gao, Li Zhang, Jing Xie

“…The factors affecting PMC restoration are oral health awareness, manner of restoration, family income, number of children, consumption of desserts, and toothbrushing frequency.…”
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Carbohydrate ligand engagement with CD11b enhances differentiation of tumor-associated myeloid cells for immunotherapy of solid cancers by Mei Zhang, Veronique Roche, Victor Sandoval, Claire Wolford, Zachary Senders, Julian Anthony Kim, Susan Pereira Ribeiro, Alex Yicheng Huang, Rafick-Pierre Sekaly, Joshua Lyons

“…We have applied peptide microarrays, multiparameter FACS (fluorescence-activated cell analysis) analysis, cellular/molecular immunological technology, advanced microscopic imaging, and transgenic mouse models of solid cancers, to study the interaction between BG34-200 carbohydrate ligand and CD11b protein and the resulting immunological changes in the context of solid cancers, including osteosarcoma, advanced melanoma, and pancreatic ductal adenocarcinoma (PDAC).Results Our results show that BG34-200 can bind directly to the activated CD11b on its I (or A) domain, at previously unreported peptide residues, in a multisite and multivalent manner. This engagement significantly impacts the biological function of tumor-associated inflammatory monocytes (TAIMs) in osteosarcoma, advanced melanoma, and PDAC backgrounds. …”
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Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA by Paolo Peruzzo, Natascha Bergamin, Martina Bon, Sara Cappelli, Alessandra Longo, Elisa Goina, Cristiana Stuani, Emanuele Buratti, Andrea Dardis

“…Results Modified U1-3, U1+1 and U1+6 snRNAs were all able to increase, in a dose-dependent manner, the inclusion of exon 2 within the transcript derived from the GAA minigene harbouring the c.-32-13T>G variant. …”
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Perancangan dan Implementasi Sistem Informasi Deteksi Kesesuaian Pemanfaatan Ruang Berbasis Web dengan Fitur Geo-Intersection Pada POSTGIS by Issa Arwani, Widhy Hayuhardhika Nugraha Putra, Ghazian Hamdi, Tsania Dzulkarnain

“…In this case, an online application that can check and provide recommendations on the suitability of space utilization in a transparent and fast manner is very much needed by the community during applying for a space utilization permit. …”
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Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis by Jinwang Ye, Suyue Zhong, Huali Wan, Xing Guo, Xuanbao Yao, Qiong Liu, Liming Chen, Jian-Zhi Wang, Shifeng Xiao

“…HDAC7 could modulate astrocytic uptake and lysosomal degradation of tau proteins through a transcriptional factor EB (TFEB) acetylation-dependent manner. Specifically, deacetylation of TFEB at K310 site by HDAC7 prevented TFEB nuclear translocation with reduced lysosomal biogenesis and tau clearance in astrocytes, whereas inhibiting HDAC7 restored astrocytic TFEB acetylation level at K310 with improved tau pathology and cognitive functions in PS19 mice. …”
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A dual-band microwave sensor for glucose measurements utilizing an enclosed split ring metamaterial-based array by Abhishek Kandwal, Ziheng Ju, Louis W.Y. Liu, Rohit Jasrotia, Choon Kit Chan, Zedong Nie, Ali M. Almuhlafi, Hamsakutty Vettikalladi

“…At 9.2 GHz, there was no significant resonant frequency shift with varying glucose concentrations, but the magnitude of the reflection coefficient changed with the glucose concentration nonlinearly in an amount-dependent manner, with a sensitivity of 16.6 dB per unit glucose concentration within the clinical diabetic range. …”
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Research progress on characteristics of secondary aluminum dross and its detoxification and utilization by Kun LIN, Yuanbo ZHANG, Zijian SU, Jiamei XU, Tao JIANG

“…Hence, methods for regulating the generation of these gases in a targeted manner and efficiently recycling them are also a future direction of study.…”
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The effect of single and dual task training on the intracortical inhibition in young and old adults by Michael Wälchli, Craig Tokuno, Benedikt Lauber, Wolfgang Taube

“…Previous research has also indicated that short-interval intracortical inhibition (SICI) is modulated in a task-specific manner following explosive or balance training (Taube et al., 2020). …”
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The role of health literacy in intervention studies targeting children living with overweight or obesity and their parents—a systematic mixed methods review by Heidi Holmen, Heidi Holmen, Tone Nygaard Flølo, Tone Nygaard Flølo, Christine Tørris, Astrid Torbjørnsen, Kari Almendingen, Kirsti Riiser, Kirsti Riiser

“…Future research should focus on integrating health literacy into weight management interventions in a systematic and theory-driven manner, ensuring that these interventions are tailored to the specific needs of children and their families and can sustain behavior change over time.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?…”
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