Adipose Tissue-Derived Stromal Cells Induce a Highly Trophic Environment While Reducing Maturation of Monocyte-Derived Dendritic Cells by Morten Juhl, Bjarke Follin, Monika Gad, Jesper Larsen, Jens Kastrup, Annette Ekblond

“…Escalating ratios of ASC did not affect the concentration of IL-10 considerably, whereas the presence of IL-12 was reduced in a dose-dependent manner. Besides offsetting the IL-12/IL-10 balance, the concentrations of IDO and MIF were elevated in cocultures. …”
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Silent witnesses: unveiling the epidemic of femicides in North-west Tshwane, South Africa – a decade of analysis by Yaseen Bismilla, K. K. Hlaise, C. Van Wyk

“…The inclusion criteria comprised female cases at autopsy, with a suspected homicidal manner of death. Excluded were cases classified as suicides, accidents, or natural deaths after further examination. …”
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Butterfly Pea and Roselle Combination Extracts Reduce V-CAM, ICAM, and IL-6 Levels in High Fat Atherogenic Diet Rats by Karnirius Harefa, Ahmad Hafizullah Ritonga, Riri Safitri, Barita Aritonang, Rahmad Gurusinga, Irmayani Irmayani, Sri Wulan

“…CONCLUSION: Administration of BPRCE in atherosclerosis rats model reduces VCAM-1, ICAM-1, and IL-6 in a dose-dependent manner. This study showed that using BPRCE as a traditional remedy for preventing and treating CHD at an optimal dose of 500 mg/kgBW might be a potential future application in reducing atherosclerosis biomarkers. …”
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Understanding the use of the National Early Warning Score 2 in acute care settings: a realist review protocol by Nia Roberts, Geoff Wong, Michelle Treacy, Mandy Odell

“…Introduction Failure to recognise and respond to patient deterioration in an appropriate and timely manner has been highlighted as a global patient safety concern. …”
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Starvation Affects the Muscular Morphology, Antioxidant Enzyme Activity, Expression of Lipid Metabolism-Related Genes, and Transcriptomic Profile of Javelin Goby (Synechogobius has... by Xiangning Chen, Yili Xu, Xiangyu Cui, Siying Zhang, Xiangqi Zhong, Juntao Ke, Yuze Wu, Zhiyu Liu, Chaoqing Wei, Zhujin Ding, Jianhe Xu, Hanliang Cheng

“…However, inducing starvation in a controlled manner cannot only reduce feed consumption but also reduces aquatic eutrophication and even improves farmed fish quality. …”
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Frau im Rechtsalltag von Vilnius und Kaunas in der ersten Halfte des 16. Jhs: Zeichen des modem werdenden Lebens by Jolanta Karpavičienė

“…Die zahlreichen Beispiele zeugen davon, dass die Bewohnerinnen der Städte ziemlich oft ihre Angelegenheiten in den Selbstverwaltungsinstitutionen oder in den Ämtern der staatlichen territorialen Verwaltung, die auch in den Städten residierten, ohne Begleitung der Männer erledigten. Die Frauen konnten selbständig sich über Gewalt, materiellen Schaden, Beleidigung beklagen, Vermögensgeschäfte abschließen, manchmal sogar im Namen ihres Mannes prozessieren. …”
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Throughout Maximization for IRS-Assisted WPCN With Hybrid TDMA-NOMA Scheme by Yizheng Ma, Ruoyi Wu, Yi Zhang, Yupeng Shang, Linzhen Zhu

“…These devices firstly collect energy in a non-linear manner disseminated by a power station (PS) at downlink wireless energy transfer (WET) stage. …”
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Propofol Priming for Enhancing Induction Safety in Hypertensive Patients: A Prospective Double-blind Randomised Controlled Trial by Tarun Yadav, Mayuri Golhar, Chhavi Saini

“…Introduction: Propofol is popular for inducing general anaesthesia, but it has drawbacks such as hypotension and bradycardia in a dose-dependent manner, especially in hypertensive patients. Reducing the total dose of Propofol using the priming principle has proven to be effective; however, it has not been studied in high-risk hypertensive patients. …”
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Perilaku Caring Perawat dengan Kepuasan Pasien di Ruang Rawat Inap Private Care Centre RSUP Dr Wahidin Sudirohusodo Makassar by afa ilkafah

“…Therefore expected to nurses in order to provide optimal service to provide services in a professional manner to cultivate caring behavior in the daily service. …”
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“You’re telling us to go first?!” COVID-19 pandemic and vaccination experiences among Aboriginal adults in Western Australia by Samantha J. Carlson, Carla Puca, Paige Wood-Kenney, Justin Kickett, Valerie Swift, Katie Attwell, Christopher C. Blyth

“…Data was thematically analysed in an inductive manner on NVivo, followed by a data interpretation forum with study investigators and community members. …”
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Identifying facilitators and barriers to culturally responsive communication for racial, ethnic, sexual, and gender minoritized patients when screened for COVID-19 vaccinations: A... by Nikhil Kalita, Patrick G Corr, Maranda C Ward, Julia Xavier, Paige L McDonald

“…Correspondingly, improving the capacity of PCPs to communicate with patients in a culturally responsive manner may influence improved screening and treatment outcomes for minoritized groups related to COVID-19. …”
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The small GTPases FoRab5, FoRab7, and FoRab8 regulate vesicle transport to modulate vegetative development and pathogenicity in Fusarium oxysporum f. sp. conglutinans by Xiangyu Tan, Lin Chen, Ying Chen, Yuxin Li, Lihan Lu, Erfeng Li

“…Laccase and glucoamylase activities decreased in a significant manner. Moreover, there was a decrease in the pathogenicity of cabbage seedlings. …”
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MECHANISMS FOR ENSURING THE ECONOMIC DEVELOPMENT OF RURAL AREAS THROUGH THE FORMATION OF THEIR ENERGY DEPENDENCE BASED ON THE INTENSIFICATION OF BIOFUEL PRODUCTION by Yuliia Okhota, Denys Titov, Svitlana Dotsiuk

“…In order to implement energy independence in an effective manner, there is a necessity to improve the legislative framework, encourage investment in biomass storage and transportation infrastructure, and foster collaboration between local governments and state institutions. …”
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Distinct dynamic regulation of pectoralis muscle metabolomics by insulin and the promotion of glucose-lipid metabolism with extended duration by Xiangli Zhang, Pengfei Du, Ziyang Wang, Yao Zhu, Xuemeng Si, Wen Chen, Yanqun Huang

“…Metabolomic analysis revealed that insulin promotes the downregulation of 63 out of 71 metabolites at 15 min and the upregulation of 101 out of 134 metabolites at 120 min, mainly associated with lysine degradation and thyroid hormone signaling pathways, respectively. 7 metabolites were dynamically modulated in the same manner over time (2 up-up and 5 down-down). Early insulin inhibited glycolysis, evidenced by the reduction in phosphoenolpyruvate levels and hexokinase 2 (HK2) expression; however, insulin promoted glucose uptake through the activation of glucose transporter 4 (GLUT4) and enhanced glycolysis, accompanied by elevated fatty acid metabolism at the later phase.In conclusion, insulin dynamically regulates the metabolomics of the pectoralis muscle over time. …”
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Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling by Xian Jin, Liang Liu, Yaping Zhang, Yin Xiang, Guizhi Yin, Yi Lu, Ludong Shi, Jian Dong, Chengxing Shen

“…In vitro, when the monocytes were treated with different dosages of AGEs (50, 150, and 300 μg/mL), we found that proliferation (CCK8) but not apoptosis (FCM) of the monocytes was induced; the mRNA expressions of proinflammatory cytokines (IL-1β and TNF-α) and GM-CSF were upregulated in a dose-dependent manner while mRNA levels of IL-10 and M-CSF were changed much less in monocytes (real-time PCR). …”
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Effect of Qingjie Fuzheng Granules on Proliferation, Apoptosis and Migration of Colorectal Cancer SW620 Cells by Xiaoqin ZHU, Hong YANG, Bin HUANG, Lihui WEI, Jiumao LIN

“…The expressions of Ki-67, MMP-2 and Cleaved-Caspase-3 proteins were detected by Western blot assay after 24 h.Results:(1) In the concentration range of 0,0.5,1,2 mg/mL, QFG significantly reduced the cell proliferation in a time and dose-dependent manner. The differences were statistically significant when compared with the control group in the same time (<italic>P</italic>&lt;0.05). (2) After treatment with 0.5,1,2 mg/mL QFG for 24 hours, the morphology of the cells changed significantly. …”
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Tibial tubercle transfer SurgeRy and physiothErapy Versus physIotherapy only for chronic paTellofemorAL paIn: study protocol for a randomiSed controllEd trial (REVITALISE) by Myrthe P. F. van de Ven, Martin Ophey, Victor van de Graaf, Sebastiaan A. W. van de Groes, Marijn Sinkeldam, Charlotte H. W. Wijers, Sander Koëter

“…Methods A single-centre nonblinded RCT in 40 patients with chronic PFP (> 1 year) and tibial tubercle-trochlear groove (TT-TG) > 15 mm will be randomised to either TTT followed by PT or to PT alone in a 1:1 ratio in a concealed manner. The primary outcome is knee pain at 18 weeks for the TTT group (6 weeks splint phase + 12 weeks PT) and at 12 weeks for the PT group, measured by the visual analog scale (VAS). …”
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Ecological validity and inclusivity in heritage bilingualism research: Examining objective and subjective Spanish proficiency assessments and language experience factors by Alicia Luque, Alicia Luque, Alicia Luque, Bryan Koronkiewicz, Bernard Issa, Mandy Faretta-Stutenberg, Harriet Wood Bowden

“…By critically evaluating the reliability and validity of existing objective and subjective proficiency assessments alongside HL experience factors, our study aims to shed light on the best practices of assessing language proficiency among bilingual individuals, specifically HSs of Spanish in the US, in an ecologically valid and inclusive manner.…”
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Calcitonin Gene-Related Peptide (Cgrp), Adrenomedullin (Am), Amylin, And Calcitonin (Ct) Receptors And Overlapping Biological Actions by J.A. Fischer, W. Born, R. Muff

“…For the related bioactive peptides, receptor-binding sites linked to cAMP stimulation and to a lesser extent to the phospholipase C signaling pathway have been identified in tissue specific manner. The highest density of CGRP receptors has been recognized in the cerebellum and the spinal cord. …”
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The impact of chronic intermittent hypoxia on enzymatic activity in memory-associated brain regions of male and female rats by Steve Mabry, Jessica L. Bradshaw, Jennifer J. Gardner, E. Nicole Wilson, Janak Sunuwar, Hannah Yeung, Sharad Shrestha, J. Thomas Cunningham, Rebecca L. Cunningham

“…Conclusions Overall, these data indicate CIH dysregulates protease activity and impairs neuronal function in a brain region- and sex-dependent manner. This indicates that males and females exhibit sex-specific vulnerabilities to mild OSA. …”
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