FOSL1 transcriptionally dictates the Warburg effect and enhances chemoresistance in triple-negative breast cancer by Gang Zhao, Yutong Liu, Shiqi Yin, Runxiang Cao, Qian Zhao, Yifan Fu, Ye Du

“…Notably, FOSL1 promotes tumor growth in TNBC in a glycolysis-dependent manner, as inhibiting glycolysis with 2-Deoxy-D-glucose markedly diminishes the oncogenic effects of FOSL1 in TNBC. …”
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THE DEVELOPMENT OF SCIENCE AND THE FATE OF A SCIENTIST (FOLLOWING GENETICS) by Jonas Rubikas

“…After obtaining a particular degree, a declination of the world line appears with the age and absence of renovation of methodology, if the scientist remains in the laboratory as a working person; this is the natural manner of the delta increase. If a scientist begins an administrative career, honorary titles, degrees, posts, and salaries make the declination marked. …”
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Maternal nutrition and offspring lung health: sex-specific pathway modulation in fibrosis, metabolism, and immunity by Shuangyi Zhao, Zhimin Chen, Huina Liu, Xinyan Wang, Xiuru Zhang, Huirong Shi

“…Results: Maternal HSD significantly altered lung transcriptomes in a sex-specific manner. Male offsprings showed increased susceptibility to fibrosis, as confirmed by histological and molecular analyses, including elevated expression of α-SMA, collagen I, Fn1, and TGF-β. …”
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Relevance of tumor boards for the inclusion of patients in oncological clinical trials by Hendrik Dapper, Maurice Dantes, Peter Herschbach, Hana Algül, Volker Heinemann

“…In the first phase, various MDTs’ case discussions about oncological situations and their decisions regarding possible therapy trials were recorded in a structured manner. In the second phase, the actual inclusion rates of patients in therapy trials and reasons for non-inclusion were examined. …”
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Potential of Regional Ionosphere Prediction Using a Long Short‐Term Memory Deep‐Learning Algorithm Specialized for Geomagnetic Storm Period by Jeong‐Heon Kim, Young‐Sil Kwak, YongHa Kim, Su‐In Moon, Se‐Heon Jeong, JongYeon Yun

“…To test and verify the predictive performance and the usability of the LSTM model for geomagnetic storms developed in this manner, we created and diagnosed the 0.5, 1, 2, 3, 6, 12, and 24‐h predictive LSTM models. …”
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Gemelos digitales pulmonares by Ana Fernández-Tena, Carlos Arnedo, Guillaume Houzeaux, Beatriz Eguzkitza

“…Abstract: The development of lung digital twins (DTs) represents a significant advance in personalized medicine, providing a virtual framework that replicates the structure, function, and pathology of the respiratory system in an individualized manner. DTs integrate clinical data, high-resolution images, and mathematical models to simulate respiratory mechanics, gas diffusion, and fluid dynamics in real time. …”
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N6-methyladenosine regulates metabolic remodeling in kidney aging through transcriptional regulator GLIS1 by Li Xu, Shuo Chen, Qiuling Fan, Yonghong Zhu, Hang Mei, Jiao Wang, Hongyuan Yu, Ying Chen, Fan Liu

“…Conclusions Our findings suggest that the m6A modification of GLIS1, activated by METTL3 and reduced in a YTHDF1-dependent manner, leads to kidney aging by regulating the metabolic shift from FAO to glycolysis. …”
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Collagen-1 and elastin expression in cervical tissue: A comparison across cervical elongation, pelvic organ prolapse, and combined conditions by Anis Widyasari, Gatut Hardianto, Etty Hari Kusumastuti, Eighty Mardiyan Kurniawati

“…Two experienced pathologists conducted the analyses in a blinded manner to ensure objective evaluation. Results: Statistical analysis using the Kruskal-Wallis test revealed significant differences in the expression of Collagen-1 across the four groups (CE, POP, CE with POP, and control). …”
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Mobile base station site as a virtual power plant for grid stability by Jussi Laimio, Mika Keski-Heikkilä, Matti Pärssinen, Roope Lahti, Olli Salmela, Topi Volkov, Jari Collin, Petri Rannikko, Henri Koskela, Jukka Manner

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Immunomodulatory effects of thymol and cinnamaldehyde in chicken cell lines by C. Shen, L.G. Christensen, S.Y. Bak, N. Christensen, K. Kragh

“…Epithelial integrity of LMH cells (as assessed by TEER) was increased by TCB (10 ng/ml) after 4 h incubation, versus untreated controls, and phagocytic capacity of HD-11 cells was increased, in a dose-dependent manner (P<0.05). In HD-11 cells, TCB (10 ng/ml) downregulated the relative expression of pro-inflammatory cytokines interleukin (IL)-1β, IL-6, IL-8 and the transcription factor cyclooxygenase-2 and upregulated expression of anti-inflammatory IL-10, versus untreated controls (P<0.05). …”
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MATHEMATICAL RATIONALE FOR CREATING AN APPLICATION FOR CONDUCTING RANDOM MEETINGS «COFFEE BREAK» by Vadym Ziuziun, Daniil Osoka

“…This study’s findings lay the groundwork for a new tool that encourages in-person interactions, enabling individuals to expand their social networks in a balanced and purposeful manner.…”
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Comparison of Medical Students&rsquo; Peer Evaluation and Teaching Staff Evaluation of Community Health Projects: Perceptions and Experiences by Mahmoud MA, Almutairi ZS, Mahmoud AM, Alanazi HB, Abdulrahman SM, Bin Abdulrahman KA

“…Both groups evaluated the project’s level of innovation and the clarity of its target audience in a comparable manner. The analysis of the Full Project Level indicated no substantial disparity between medical students and Staff, as evidenced by the p-value of 0.920.Conclusion: This study validates that peer evaluation of student projects is equally practical as evaluation conducted by faculty members. …”
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Cobalt oxide nanoparticles induce cytotoxicity and excessive ROS mediated mitochondrial dysfunction and p53-independent apoptosis in melanoma cells by Hanan R. H. Mohamed, Basma A. Mohamed, George M. Hakeem, Shahd H. Elnawasani, Maria Nagy, Rawan Essam, Ayman Diab, Gehan Safwat

“…These findings highlight the novel potential of Co3O4NPs as potent inducers of melanoma A-375 cell death in a concentration-dependent manner through excessive ROS production, genomic instability, mitochondrial dysfunction and dysregulation of apoptotic and mitochondrial gene expression, ultimately promoting apoptosis in A-375 cells. …”
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PreciPalm: An Intelligent System for Calculating Macronutrient Status and Fertilizer Recommendations for Oil Palm on Mineral Soils Based on a Precision Agriculture Approach by Kudang Boro Seminar, Harry Imantho, null Sudradjat, Sudirman Yahya, Sirojul Munir, Indra Kaliana, Fajar Mei Haryadi, Awalia Noor Baroroh, null Supriyanto, Gani Cahyo Handoyo, Arif Kurnia Wijayanto, Cecep Ijang Wahyudin, null Liyantono, Rhavif Budiman, Achmad Bakir Pasaman, Dwi Rusiawan, null Sulastri

“…The novelty of PreciPalm is that it provides an ecosystem to transparently measure and observe the macronutrient status of oil palm in a timely, visual, spatial, and location-specific manner, thereby improving oil palm nutritional management with more certainty and precision.…”
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The Impact of Teacher Training on The Academic Performance of Student's Among Secondary Schools in Mbarara District: A Case Study of Kashari County Uganda. by Amumpaire, Catherine

“…Due to a lack of in-service training, the teachers continue to deliver content in a disorganized manner, and teacher-centered teaching and are not able to link class teaching to the immediate environment so that students can relate well. …”
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The Impact of Teacher Training on The Academic Performance of Student's Among Secondary Schools in Mbarara District: A Case Study of Kashari County Uganda. by Amumpaire, Catherine

“…Due to a lack of in-service training, the teachers continue to deliver content in a disorganized manner, and teacher-centered teaching and are not able to link class teaching to the immediate environment so that students can relate well. …”
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Effectiveness of the Local Natural Methods of Extending Fruit Shelf Life in Selected Cooler Parts of Uganda. by Mwesigye, Deus

“…NaCl and applying aloe vera gel on the surface of avocados in a safer and health-conscious manner is paramount. Avocados are prone to postharvest deterioration caused by mechanical damage, rodent insect attack, and microbial activity. …”
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Antiviral Activity of Plant‐Based Additives Against African Swine Fever Virus (ASFV) in Feed Ingredients by Thi Ngoc Ha Lai, Thi Bich Ngoc Trinh, Thi Tam Than, Nguyen Tuan Anh Mai, Niku Moussavi Biuki, Bernhard Eckel, Viktor P. L. Eckel, Thi Lan Nguyen, Van Phan Le

“…Conclusions All additives, OAB, Phyto.A04 and Phyto.B, were able to inactivate ASFV in a dose‐dependent manner, as confirmed by cell culture and PCR methods. …”
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Oleanolic Acid Induces Differentiation of Neural Stem Cells to Neurons: An Involvement of Transcription Factor Nkx-2.5 by You Ning, Jianhua Huang, Bill Kalionis, Qin Bian, Jingcheng Dong, Junzhen Wu, Xiantao Tai, Shijin Xia, Ziyin Shen

“…We found OA significantly inhibited neurosphere formation in a dose-dependent manner and achieved a maximum effect at 10 nM. OA also reduced 5-ethynyl-2′-deoxyuridine (EdU) incorporation into NSCs, which was indicative of inhibited NSC proliferation. …”
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Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS by Adam Eckardt, Charles Marble, Bradley Fern, Henry Moritz, Charles Kotula, Jiayi Ke, Clarisse Rebancos, Samantha Robertson, Hiroshi Nishimune, Masatoshi Suzuki, Masatoshi Suzuki

“…Although ALS has historically been characterized as a motor neuron disease, there is evidence that motor neurons degenerate in a retrograde manner, beginning in the periphery at the neuromuscular junctions (NMJs) and skeletal muscle. …”
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