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2941
Essential oils from Amorpha fruticosa against hepatocellular carcinoma based on network pharmacology
Published 2025-01-01“…Both AFLEO and AFFEO inhibited the proliferation of HCC cells in a time and dose-dependent manner. 10 compounds of AFLEO and 9 compounds of AFFEO were screened out for further analysis. 28 hub targets of AFLEO and 40 hub targets of AFFEO were detected by PPI network. …”
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2942
High-Intensity Focused Ultrasound (HIFU) Focal Therapy for Localized Prostate Cancer with MRI-US Fusion Platform
Published 2021-01-01“…HIFU focal therapy was performed in the conventional manner in the beginning 50% of the series, whereas the subsequent cases were performed with MRI-US fusion platform. …”
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2943
Solving Nonlinear Energy Supply and Demand System Using Physics-Informed Neural Networks
Published 2025-01-01“…The key factors influencing this include the manner in which the neural network architecture is designed, such as the selection of hyperparameters and appropriate optimization functions. …”
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2944
The Role of Leadership, Religiousness and Work Environment in Supporting Employee Performance and How Motivation Affects The Relationship
Published 2025-01-01“…Originality/Value (State of The Art): This study highlights the importance of religiosity as a factor that has a positive impact on employee performance, especially if religious values are applied in a balanced and constructive manner. Leadership values driven by religiosity can improve employee performance and create a harmonious work environment. …”
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2945
A Research on the Effect of Heterogeneities on Sandstone Matrix Acidizing Performance
Published 2019-01-01“…However, sandstone formations inevitably have small-scale heterogeneities of minerals and flow properties that may give rise to acid propagation in a manner much different from what is predicted based on homogeneous assumptions. …”
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2946
Fuzzy Logic Recommender Model for Housing
Published 2025-01-01“…The model predicts a percentage of membership in each cluster, which makes it possible to handle uncertainty by offering properties from different groups in a proportional manner. Euclidean distance is employed in order to measure the similarity between user preferences and housing characteristics, after which the search time is optimized by utilizing metaheuristic methods, of which the bat algorithm provides the best performance in terms of time. …”
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2947
Injury mortality in South Africa: a 2009 and 2017 comparison to track progress to meeting sustainable development goal targets
Published 2024-12-01“…Age-standardised rates, 95% confidence intervals (CIs), and incidence rate ratios (IRRs) were calculated for manner of death rate comparisons and for age groups. …”
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2948
Dynamic Expression of HDAC3 in db/db Mouse RGCs and Its Relationship with Apoptosis and Autophagy
Published 2020-01-01“…In this study, we examined the morphological and immunohistochemical changes of HDAC3, Caspase3, and LC3B in a sequential manner by characterizing the process of retinal ganglion cell variation. …”
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2949
miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway
Published 2021-01-01“…The miR-149 level in HUVECs was reduced by ox-LDL (100 μg/mL) incubation in a time-dependent manner. miR-149-mimic transfection markedly protected HUVECs from ox-LDL-induced injury, with increased cell viability and reduced caspase-3 activity. miR-149 mimics enhanced HUVEC autophagy, which was induced initially by ox-LDL. miR-149 mimics also markedly downregulated the expression of Akt, p-Akt, mTOR, and p-mTOR in ox-LDL-treated HUVECs. …”
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2950
NK-92 cells activated by IL-2 inhibit the progression of endometriosis in vitro
Published 2024-12-01“…Each experiment was repeated three times.Results IL-2 activation enhanced NK-92 cytotoxicity in a concentration-dependent manner. Co-culturing EESCs with IL-2-activated NK-92 cells at E:T ratios of 1:1, 1:3, and 1:9 reduced EESC viability by 20%, 45%, and 70%, respectively, compared to the control group. …”
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2951
Identification of a Novel lincRNA-p21-miR-181b-PTEN Signaling Cascade in Liver Fibrosis
Published 2016-01-01“…In LX-2 cells, the reduction of lincRNA-p21 induced by TGF-β1 was in a dose- and time-dependent manner. lincRNA-p21 expression was reduced in liver tissues from patients with liver cirrhosis when compared with that of healthy controls. …”
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2952
Evaluation of Leea rubra Leaf Extract for Oxidative Damage Protection and Antitumor and Antimicrobial Potential
Published 2021-01-01“…The oxidative hemolysis caused by AAPH in human erythrocytes was inhibited by EAF extract in a time-dependent manner, and the production of malondialdehyde (MDA) was significantly reduced, which indicates the prevention of lipid peroxidation. …”
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2953
Postcards from Inside the Practices
Published 2025-02-01“…Instead, their panel was designed to explore making-knowledge with others in a manner that is improvisatory, non-authoritative, and open to the silence of gestures and quiet exchange. …”
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2954
Opposing Effects of Omega-3 and Omega-6 Long Chain Polyunsaturated Fatty Acids on the Expression of Lipogenic Genes in Omental and Retroperitoneal Adipose Depots in the Rat
Published 2010-01-01“…Altering red blood cell concentrations of n-3 PUFA is thus associated with altered expression of lipogenic genes in a depot-specific manner and this effect is modulated by prevailing n-6 PUFA concentrations.…”
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2955
Critical analysis of doctrinal approaches to the definition of “biological terrorism”
Published 2023-09-01“…Terrorism has been defined as socially dangerous criminal acts provided for by international and national law, which consist of demonstrative public violence in a generally dangerous manner or with particular cruelty, as well as threats, organisation, preparation, logistical, financial and other support or incitement to commit such acts aimed at intimidating the population, inducing specific institutions or individuals to commit or refuse to commit certain acts, or with the aim of destabilising or destroying law and order. …”
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2956
Silver Nanoparticles Stabilized by Poly (Vinyl Pyrrolidone) with Potential Anticancer Activity towards Prostate Cancer
Published 2022-01-01“…In vitro cytotoxicity testing showed the AgNPs-PVP exhibited antiproliferation properties in PC3 in a dose-dependent manner. In addition, when compared to control cells, AgNPs-PVP has lower TNF-α with a significant value (∗p<0.05); the value reached 16.84 ± 0.71 pg/ml versus 20.81 ± 0.44 pg/ml, respectively. …”
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2957
Expert decision-making in clinicians: An auto-analytic ethnographic study of operational decision-making in urgent care.
Published 2025-01-01“…Expert solutions generated in this manner are pragmatic rather than optimal, context dependent, and seek to achieve goals which vary from moment-moment. …”
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2958
Migrated intra-uterine device to infra-umbilical skin: a rare case report
Published 2024-12-01“…Removal of misplaced IUD with completely non-invasive manner makes this case special in addition to the unique site of migration to the infra-umbilical skin. …”
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2959
Enhanced Disc Herniation Classification Using Grey Wolf Optimization Based on Hybrid Feature Extraction and Deep Learning Methods
Published 2024-12-01“…The aim of this study was to classify lumbar disc herniations in a computer-aided, fully automated manner using magnetic resonance images (MRIs). Methods: This study presents a hybrid method integrating residual network (ResNet50), grey wolf optimization (GWO), and machine learning classifiers such as multi-layer perceptron (MLP) and support vector machine (SVM) to improve classification performance. …”
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2960
Knowledge, Attitude and Practice of Medical Students of Sulaimani Regarding Modern Lifestyle and Its Effect on Health
Published 2020-12-01“…A cross sectional study was conducted among 420 students, in a convenient sampling way, Data collected from 18th to 22nd of September 2019 in a self-administrated manner from four different medical colleges (Medicine, Dentistry, Pharmacy and Veterinary.) in university of Sulaimani. …”
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