In Vivo Antimalarial Activity of 80% Methanol and Aqueous Bark Extracts of Terminalia brownii Fresen. (Combretaceae) against Plasmodium berghei in Mice by Hana Biruk, Biruk Sentayehu, Yonatan Alebachew, Wondmagegn Tamiru, Abebe Ejigu, Solomon Assefa

“…Moreover, the 80% methanol extract showed a significant p<0.001 attenuation of anemia associated with infection in a dose-dependent manner. The aqueous extract, on the other hand, exhibited a percent inhibition of 51.1% at the highest dose (400 mg/kg/day). …”
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Uncovering the whole genome silencers of human cells via Ss-STARR-seq by Xiusheng Zhu, Lei Huang, Chao Wang, Guoli Li, Biao Deng, Dashuai Kong, Xiaoxiao Wang, Rongrong Chang, Yi Gu, Qiuhan Wen, Siyuan Kong, Yuwen Liu, Yubo Zhang

“…In this study, we applied Ss-STARR-seq to human cell lines K562, LNCaP, and 293 T, and identified 134,171, 137,753, and 125,307 silencers on a genome-wide scale, respectively, these silencers function in various cells in a cell-specific manner. Silencers exhibited a substantial enrichment of transcriptional-inhibitory motifs, including REST, and demonstrated overlap with the binding sites of repressor transcription factors within the endogenous environment. …”
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Pseudomonas cold shock proteins suppress bacterial effector translocation in Nicotiana benthamiana by Shen Cong, Jun-Zhou Li, Mei-Ran Zhang, Mei-Ran Zhang, Hai-Lei Wei, Wei Zhang

“…Genetic analysis revealed that these CSPs did not contribute to the ROS burst or HR inhibition in vivo but were functionally redundant in suppressing effector translocation in a flagellin (FliC)-independent manner. Furthermore, we demonstrated that the suppression of effector translocation mediated by CSPs was less pronounced compared to that triggered by FliC. …”
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An analysis of referral patterns of traumatic brain injury at Groote Schuur Hospital Trauma Centre by N Parker, T Navsaria, M Lopez, L Marineau, R Maine, K Chu, T Govender, D McPherson, P Navsaria

“…Traumatic brain injury (TBI) can result in significant morbidity and mortality if not diagnosed in a timely manner. Brain computed tomography (CT) is the diagnostic gold standard but is of limited availability in most South African public hospitals, resulting in transfer of TBI patients to tertiary hospitals. …”
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Comparative Analysis of Immunoactivation by Nanosecond Pulsed Electric Fields and PD-1 Blockade in Murine Hepatocellular Carcinoma by Maiweilidan Yimingjiang, Talaiti Tuergan, Xinhua Chen, Hao Wen, Yingmei Shao, RuiQing Zhang, Kasimu Aihaiti, Jing Xue, Tuerganaili Aji, Wei Zhang

“…Based on these findings, both nsPEF ablation and PD-1 antibody administration can trigger a local and systemic immune response in a partially complementary manner, and nsPEF ablation should be considered along with PD-1 blockade for the treatment of HCC.…”
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Pochonia chlamydosporia synergistically supports systemic plant defense response in Phacelia tanacetifolia against Meloidogyne hapla by Jana Könker, Jana Könker, Sanja Zenker, Sanja Zenker, Anja Meierhenrich, Anja Meierhenrich, Anant Patel, Karl-Josef Dietz, Karl-Josef Dietz

“…The results support the conclusion that P. chlamydosporia induces plant defense in a distinct and beneficial manner if combined with M. hapla although plant defense is partly suppressed by the endophytic growth. …”
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A Brief Review of Hydrogels for Drug Delivery for Different Organs of the Body: Synthesis, Categorization, and Organ-Specific Applications by Azadeh Asefnejad, Nesa Rastgoo, Shirin Ardeshiriansharifabadi, Samira Basir Shabestari, Tohid Khodadadi, Foad Iranmanesh

“…Hydrogels have emerged as a promising class of biomaterials for drug delivery applications due to their unique physicochemical properties, including high water content, soft and rubbery texture, and ability to encapsulate and release therapeutic agents in a controlled manner. This review article provides a comprehensive overview of the synthesis, types, and applications of hydrogels in various organs of the body for drug delivery. …”
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Exercise during pregnancy modulates infant cellular and whole‐body adiposity by Alex Claiborne, Filip Jevtovic, Donghai Zheng, Cody Strom, Breanna Wisseman, Samantha McDonald, Edward Newton, Steven Mouro, James DeVente, Joseph A. Houmard, Nicholas T. Broskey, Linda E. May

“…In utero exposure to exercise reduced cellular and whole‐body infant adiposity in a dose‐dependent manner.…”
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Nootkatone Derivative Nootkatone-(E)-2-iodobenzoyl hydrazone Promotes Megakaryocytic Differentiation in Erythroleukemia by Targeting JAK2 and Enhancing JAK2/STAT3 and PKCδ/MAPK Cro... by Yang Pan, Feng Xiao, Chaolan Pan, Hui Song, Peng Zhao, Meijun Chen, Liejun Huang, Jue Yang, Xiaojiang Hao

“…Our results demonstrate that the nootkatone derivative nootkatone-(E)-2-iodobenzoyl hydrazone (N2) significantly inhibited erythroleukemia cell proliferation in a concentration- and time-dependent manner. More importantly, N2 induced megakaryocytic differentiation, as evidenced by significant morphological changes, and upregulation of megakaryocytic markers CD41 and CD61. …”
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Investigation of predictors of interest in a brief mindfulness-based intervention and its effects in patients with psoriasis at a rehabilitation clinic (SkinMind): an observational... by Laura Stadtmüller, Markus Eckardt, Christoph Zick, Joerg Kupfer, Christina Schut

“…In addition, mediation analyses will be used in an explorative manner to test whether there is a relationship between mindfulness/self-compassion and the severity of PS and whether it is mediated by itch catastrophising and fear of negative evaluation (first model) or perceived stress (second model).Ethics and dissemination The study protocol has been approved by the University of Giessen. …”
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விவேக சிந்தாமணி கூறும் மானுட விழுமியங்கள் / Human Values in Viveka Cintamani by முனைவர் சு. சுசா / Dr. S. Susa

“…Unlike other ethical works, it not only teaches principles but also presents them in an accessible manner through poems and stories featuring animals such as rabbits, lions, and foxes. …”
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Spatiotemporal Distribution Characteristics of Mesoscale Convective Systems Producing Short-Duration Heavy Rainfall over the Tianshan Mountain Area by Jiangang Li, Lianmei Yang, Wen Liu, Cailian Jiang

“…In terms of tracks, most MCSs moved eastward under the influence of the westerlies and the MαCSs moved faster but in a more scattered manner than the MβCSs. Additionally, some unusual tracks appeared because of the effects of the underlying surface topography and environmental wind.…”
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Implementation outcomes of HIV self-testing in low- and middle- income countries: A scoping review. by Adovich S Rivera, Ralph Hernandez, Regiel Mag-Usara, Karen Nicole Sy, Allan R Ulitin, Linda C O'Dwyer, Megan C McHugh, Neil Jordan, Lisa R Hirschhorn

“…Both quantitative and qualitative results were extracted and synthesized in a narrative manner.<h4>Results and discussion</h4>Most (75%) of the 206 included articles focused on implementation in Africa. …”
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Design of an integrated model with temporal graph attention and transformer-augmented RNNs for enhanced anomaly detection by Sai Babu Veesam, Aravapalli Rama Satish, Sreenivasulu Tupakula, Yuvaraju Chinnam, Krishna Prakash, Shonak Bansal, Mohammad Rashed Iqbal Faruque

“…We employ a Multimodal Variational Autoencoder-MVAE that fuses video, audio, and motion sensor information in a manner resistant to noise and missing samples. To address the challenge of having a few labeled anomalies, we apply the Prototypical Networks to perform few-shot learning and enable generalization based on a few examples. …”
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ANALYSIS OF RELATIONSHIP BETWEEN FLEXIBLE WORK ARRANGEMENTS, WORK LIFE BALANCE AND EMPLOYEES’ EFFICIENCY: EVIDENCE FROM BOSNIA AND HERZEGOVINA’S (BiH) IT SECTOR by Ognjen Riđić, Adnan Avdibegović, Senad Bušatlić

“…The study was conducted in a cross-sectional time manner in the period June-July 2016. A modified, 18 questions, primary quantitative survey instrument with a 5-point Likert scale was conducted on 503 Bosnian IT employees. …”
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Pneumothorax, Pneumomediastinum, and Cervical and Facial Massive Emphysema Secondary to Colonoscopy: A Rare Complication of Colonoscopy by Ruben Daniel Perez Lopez, Julian Vargas Flores, Lenin de Jesus Orbe Garibay, Hugo Fernando Narvaez Gonzalez

“…The purpose of presenting this case is for the doctor who performs these interventions to suspect this complication in a timely manner, not delaying the diagnosis and carrying out an urgent therapeutic approach as in this case with exploratory laparotomy, finding the perforation site and carrying out the corresponding surgical management. …”
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Challenges in Bootstrapping a Start-Up Venture: Keenga Research Turning the Tables on Venture Capitalists by Prescott C. Ensign, Anthony A. Woods

“…Can the concept be developed and brought to market in a timely manner? Will the product generate revenue? How? When? …”
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Ischemic Postconditioning Mitigates Retinopathy in Tree Shrews with Diabetic Cerebral Ischemia by Ling Zhao, Qiwei Liao, Yueting Zhang, Shufen Tan, Shuqing Li, Tingyu Ke

“…Diabetes and cerebral ischemia increased retinal VEGF expression in a step-wise manner, while additional ischemic PC reduced retinal VEGF expression. …”
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Psychiatric Symptoms in Acute Intermittent Porphyria - Case Report and Course of Treatment Using Placebo by Waldemar Kosiba, Dominika Prystacka-Szar, Jakub Siemko, Wojciech Kupczak

“… Introduction: Acute intermittent porphyria is a disease inherited in an autosomal dominant manner, occurring with a frequency of 1:75,000 people. …”
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The finding and researching algorithm for potentially oscillating enzymatic systems by T. N. Lakhova, F. V. Kazantsev, S. A. Lashin, Yu. G. Matushkin

“…Using the method described in the article, we present and analyze, in a step-by-step manner, first the structural models (graphs) of gene networks and then the reconstruction of the mathematical models and computational experiments with them. …”
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