lncRNAs: the unexpected link between protein synthesis and cancer adaptation by Mila Gugnoni, Manoj Kumar Kashyap, Kishore K. Wary, Alessia Ciarrocchi

“…They outnumber mRNAs by an order of magnitude and their expression is regulated in an extremely specific manner depending on context, space and time. This heterogeneity is functional and allows lncRNAs to act as context-specific, fine-tuning controllers of gene expression. …”
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Identification of dequalinium as a potent inhibitor of human organic cation transporter 2 by machine learning based QSAR model by Fumihiro Yamane, Kenji Ikemura, Masayoshi Kondo, Manami Ueno, Masahiro Okuda

“…Moreover, dequalinium inhibited hOCT2-mediated transport of platinum anti-cancer agents (cisplatin and oxaliplatin) in a concentration-dependent manner. Our study is the first to demonstrate the construction of a novel machine learning-based QSAR model for hOCT2 inhibitors and identify a novel hOCT2 inhibitor among FDA-approved drugs using this model.…”
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Virtual Force-Based Swarm Trajectory Design for Unmanned Aerial Vehicle-Assisted Data Collection Internet of Things Networks by Xuanlin Liu, Sihua Wang, Changchuan Yin

“…The sense-collect-interchange-explore (SCIE) protocol is proposed to regulate UAV actions, ensuring synchronization and adaptability in a distributed manner. To maintain real-time monitoring while reducing data transmission, we introduce status freshness, which is an extension of age of information (AoI) and allows negative values to reflect the swarm’s predictive capabilities. …”
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Effects of macrolide antibiotics on blood inflammatory mediators and organ damage markers in lipopolysaccharide-induced pulmonary damage rats by Ayşe Er, Enver Yazar

“…Hovewer, investigation is need that especially dose-depended manner effects of macrolide antibiotics on immunosystem.…”
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Treatment of Priapism Secondary to Drugs for Erectile Dysfunction by José Pablo Saffon Cuartas, Carolina Sandoval-Salinas, Juan M. Martínez, Héctor A. Corredor

“…Priapism may present as a side effect in patients treated with medications for erectile dysfunction, in which it should be controlled in a timely manner to avoid complications. There is little information regarding the use of local measures for the treatment of this condition. …”
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Gut–brain axis and neuropsychiatric health: recent advances by Ceymi Doenyas, Gerard Clarke, Renáta Cserjési

“…The use of in vivo animal models has demonstrated that preformed α-synuclein fibrils (PFFs) can travel from the gut to the brain in a dosage-dependent manner, thereby supporting the “gut-first” theory in the context of PD, a theory that is explored in this Collection using in vitro approaches. …”
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Applying Educational Programming Language-Based Learning to Enhance the Programming Skills of Non-ICT Engineering College Students by Jorge Rodas-Silva, Jorge Parraga-Alava, Mariuxi Vinueza-Morales, Ana Eva Chacón Luna, Jesennia Cárdenas-Cobo

“…Educational programming languages (EPLs) such as App Lab have gained popularity as they offer an accessible platform for students to learn programming fundamentals in a visual and interactive manner. This paper examines the impact of the EPL called App Lab on the development of fundamental programming skills among non-ICT-related field engineering college students. …”
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Construction Time of Three Wall Types Made of Locally Sourced Materials: A Comparative Study by Wojciech Drozd, Agnieszka Leśniak, Sebastian Zaworski

“…The layers have been chosen in such a manner that heat transfer coefficient values for the studied variants are as equal as possible (0.2 W/m2 K), thus allowing a reliable comparative study.…”
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Fast Simulation and Chaos Investigation of a DC-DC Boost Inverter by Rachid Dhifaou, Houda Brahmi

“…First, we develop a like-discrete integration process that permits precise results in a very fast manner. For one switching period, we compute only two or a maximum of three breaking points depending on whether we treat a continuous conduction mode (CCM) or a discontinuous conduction mode (DCM) of the inductor current. …”
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Le site d’Azrou Iklane : un exemple d’usage de l’imagerie numérique pour l’étude et la préservation de l’art rupestre saharien by Gwenola Graff, Martin Loyer, Abdelhadi Ewague, Romain Simenel, Maxence Bailly

“…This model was then enriched with the survey of the engravings carried out in a vector format drawing (done with machine intelligence), a photographic coverage using Gigapixel, the virtual visits and 360° images in the manner of Google Street View. Using the data acquired, a geographical information system is now being elaborated, The Moroccan heritage services were keen supporters of this project which was an original one for the country and one that satisfied local demands for a better preservation and interpretation of the fragile engravings. …”
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The Prospects of Russia and India Jointly Leading a New Non-Aligned Movement by A. Korybko, V. M. Morozov

“…The neorealist school of International Relations Theory preaches the need to pursue national interests, which sometimes align with others', and it is argued in the article that it is with this idea in mind that both countries have a motivation to jointly improve their strategic positions relative to the People's Republic, albeit in a non-hostile manner that avoids the risk of inadvertently triggering a security dilemma and reversing the recent gains made in Eurasian integration.Two articles published by Russia's Valdai Club in 2019 indicated the possibility of creating a new Non-Aligned Movement, with the most recent one proposing that it be jointly led by Russia and India in order to advance the aforementioned neo-realist objective of balancing China. …”
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Dose and time dependent cytotoxicity of Blepharis maderaspatensis (L) against various human cancer cell lines by Bhutkar Pratima Milind, V. Suganthi, Bhutkar Milind Vishnu

“…Results: Ethanolic extract of B. maderaspatensis was effective cytotoxic agent against all the tested cancer cell lines in dose and time-dependent manner. Cytotoxicity was maximum against A375 (melanoma) (IC50: 21.46μg/ml), followed by HT29 (colon cancer) cell lines (IC50: 32.66μg/ml). …”
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Comparison of the commodity certification systems in the European Union and in the Eurasian Economic Union by Valerii Kardanov, Denis Stoikov

“…This is confirmed by the fact, that the creation and application of harmonized standards allows one to get closer to the benchmarks of sustainable development and to remove many of the modern challenges from the agenda in a timely manner.…”
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Three-Dimensional Finite Difference Analysis on the Ground-Sequential Tunneling-Superstructure Interaction by Ali Lakirouhani, Reyhaneh Jafari, Hadi Hasanzadehshooiili

“…To simulate the practical sequential tunneling procedure, tunnel excavation is conducted in a step-by-step framework; tunnel excavation starts from the beginning of the model and is updated in a continuous manner, and the installation of the tunnel support system is done with a delay step compared to tunnel excavation. …”
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Tissue-specific resistance and susceptibility to the tomato brown rugose fruit virus (ToBRFV) conferred by Solanum pennellii loci by Edan Rochsar, Shai Torgeman, Kfir Bandel, Amnon Koren, Chen Klap, Aviv Dombrovsky, Dani Zamir

“…Conclusion Taken together, S. pennellii loci conferring resistance and susceptibility act in a tissue-specific manner and are modified by genetic background.…”
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Determination of Optimal Drop Height in Free-Fall Shock Test Using Regression Analysis and Back-Propagation Neural Network by Chao-Rong Chen, Chia-Hung Wu, Hsin-Tsrong Lee

“…The primary purpose of this study is to provide methods that can be used to determine the most suitable drop height for shock testing military equipment, in an efficient and cost ineffective manner. Shock testing is widely employed to assess the performance of electronic systems, including military devices and civilian systems. …”
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Improving employee performance through compensation in savings and loans cooperatives by Sonny Hersona, Yamarthin Partogi Tarihoran, Sari Sekarini, Vicky Alvin Nugraha, Hilmy Muhammad Iqbal

“…Therefore, further recommendations for future research could involve additional variables to understand other factors that influence employee performance in a more holistic manner.…”
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Severe Acute Respiratory Syndrome Coronavirus 2 Infection Symptoms in Pregnancy and Maternal and Neonatal Complications Due to COVID-19: A Systematic Review by Sepideh Miraj, Azadeh Asgarian, Abolfazl Mohammadbeigi, Maryam Derakhshani

“…Materials and Methods: International scientific databases including PubMed, Web of Science, Scopus and Google Scholar were searched in a systematic review manner. Two independent researchers were checked and identified articles from September 2019 to September 2022 based on eligibility criteria and quality appraisal. …”
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The Effects of Nebulized Inhaled Triptolide on Airway Inflammation in a Mouse Model of Asthma by Yafang Miao, Li Wei, Hao Chen, Zeming Zhang, Li Han

“…Inhalation of nebulized triptolide can play a role in suppressing airway inflammation with inflammatory cytokines and transcriptional factors reduced and CD4+Th17+ T cells dampened, also in a manner less than injected dexamethasone.…”
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Effect of geometric characteristics of helical piles on the lateral displacement in sandy slopes by loading surcharge by Mir abas Bahri, Mahyar Arabani

“…Laboratory results also reveal that the vertical load increases by 34, 20, and 12 %, respectively by increasing the helix depth, decreasing the helix pitch, and installing the piles in a slanted manner. Furthermore, considering the results of verification through numerical analysis, the vertical load on the slope crest when reinforced with helical piles was up to 47 % higher than when reinforced with cylindrical piles with the same shaft diameter. …”
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