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2261
Role of Mas Receptor Antagonist A799 in Renal Blood Flow Response to Ang 1-7 after Bradykinin Administration in Ovariectomized Estradiol-Treated Rats
Published 2015-01-01“…Percentage change of RBF (%RBF) in response to Ang1-7 infusion increased in a dose-dependent manner. In the presence of BK, when MasR was not blocked, %RBF response to Ang 1-7 in OVE group was greater than OV group significantly (P<0.05). …”
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2262
Disparities in the Diagnosis of Hypertrophic Obstructive Cardiomyopathy: A Narrative Review of Current Literature
Published 2018-01-01“…HOCM is a frequently implicated cause of sudden cardiac death (SCD) in young athletes. In this manner, this condition has the capacity for tremendous emotional, social, financial, and medical burdens for families and communities across the country. …”
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2263
Gene Editing in Pluripotent Stem Cells and Their Derived Organoids
Published 2021-01-01“…The applications, characteristics, and existing challenges are summarized in combination with our lab experiences in this field in an effort to help gene-editing technology better serve humans in a regulated manner. Current preclinical and clinical trials have demonstrated initial safety and efficacy of PSC gene editing; however, for better application in clinical settings, additional investigation is warranted.…”
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2264
Scutellarin combined with lidocaine exerts antineoplastic effect in human glioma associated with repression of epidermal growth factor receptor signaling.
Published 2025-01-01“…<h4>Results</h4>In present study, we found that SCU and lidocaine suppressed the proliferation and migration, and induced the apoptosis of human glioma cell lines, including U251 and LN229 cells, in a dose-dependent manner in vitro. Moreover, the combination of SCU and lidocaine further restrained the proliferation and migration ability of U251 and LN229 cells, while induced their apoptosis in vitro. …”
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2265
Low-Frequency Admittance of Capacitor with Working Substance “Insulator–Partially Disordered Semiconductor– Insulator”
Published 2021-10-01“…The partially disordered semiconductor of the working substance of the capacitor can be, for example, a highly defective crystalline silicon containing point t-defects randomly (Poissonian) distributed over the crystal in charge states (−1), (0), and (+1), between which single electrons migrate in a hopping manner. It is assumed that the electron hops occur only from t-defects in the charge state (−1) to t-defects in the charge state (0) and from t-defects in the charge state (0) to t-defects in the charge state (+1).In this work, for the first time, the averaging of the hopping diffusion coefficients over all probable electron hopping lengths via t-defects in the charge states (−1), (0) and (0), (+1) in the covalent crystal matrix was carried out. …”
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2266
Educational Interventions for Haemodialysis Patients in the Transplant Process: A Systematic Review
Published 2024-12-01“…Implications for Nursing Health Education Nursing educational interventions are necessary throughout the transplantation process for the patient dialysis and the family in a comprehensive and continuous manner. In the future, clinical trial studies are needed at the pretransplantation stage.…”
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2267
SUSTAINABILITY PERFORMANCE OF INFRASTRUCTURE PROJECTS: THE CASE FOR LIFE CYCLE SUSTAINABILITY ASSESSMENT METHODOLOGY
Published 2018-06-01“…Furthermore, other postulations concerning the inability of the extant systems to cater adequately for the three sustainability dimensions in an integrated manner as well as the overt concentration on certain phases of the infrastructure asset lifecycle were affirmed. …”
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2268
Laboratory biomarkers for multiple sclerosis and their role in clinical practice
Published 2023-11-01“…However, this has also raised new challenges in predicting the course and activity of the disease before the development of new neurological deficits that aggravate the disability and in prescribing the most appropriate disease-modifying therapy for the individual patient in a timely manner. One of the possible solutions that could help answer these questions is the use of laboratory biomarkers in MS. …”
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2269
Potential of Wood Harvesting Residues and Residual Stand Damage due to Timber Harvesting: A Case Study at PT Austral Byna in Central Kalimantan, Indonesia
Published 2022-01-01“…The sample plots were arranged in a systematic and purposive manner, and the data were processed with tabulation and average analysis. …”
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2270
Pattern of the impact of social capital on crisis management performance
Published 2024-12-01“…Crisis management means purposefully shifting the flow of affairs in a controllable manner with the intention of returning things to pre-crisis conditions as soon as possible. …”
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2271
Baricitinib represses the myocardial fibrosis via blocking JAK/STAT and TGF-β1 pathways in vivo and in vitro
Published 2025-01-01“…Interestingly, in TGF-β1-stimulated cardiac fibroblasts, baricitinib decreased the expressions of Col1, Col3, α-SMA, Fn, MMP9, and TIMP1 in a dose-dependent manner (From 10 to 2000 nM), also exhibited a dose-dependent impact on the expressions of p-STAT3 and TGF-βRII. …”
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2272
SIRENA, une plateforme participative au service de la gouvernance du delta transfrontalier du fleuve Sénégal
Published 2016-07-01“…The design and data collection feeding the system are managed by mixed thematic working groups. In this manner SIRENA has established a network of partners and created a platform for multi-stakeholder dialogue, rather than only collecting data or producing new knowledge. …”
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2273
Robust Automated Harmonization of Heterogeneous Data Through Ensemble Machine Learning: Algorithm Development and Validation Study
Published 2025-01-01“…We also used gold standard labels to further refine the embeddings in a supervised manner. ResultsThe method was evaluated using manually curated gold standard labels from the 3 National Institutes of Health cohorts. …”
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2274
Cinéma et lien : une enquête intime auprès d'une famille italienne en Lorraine
Published 2012-04-01“…Moreover, cinema can be seen as an ideal and useful source of information for migrants since it often portrays the new manners and social habits of the host country. But it can also give migrants the opportunity to ponder on moral issues of a universal kind. …”
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2275
Robust dual-tone multi-frequency tone detection using k-nearest neighbour classifier for a noisy environment
Published 2025-01-01“…The proposed KNN classifier model is configured in four different manners which differ in being trained with or without augmented data, as well as, with or without the inclusion of second harmonic frequency DFT coefficient values as features. …”
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2276
Clinical Chemistry and Autoverification: A Path Less Traversed
Published 2024-05-01“…Autoverification implementation was done in stepwise manner. (i) Test selection and developing algorithms, (ii) Setting-up rules in middleware to prevent release of erroneous results, (iii) User acceptance testing (UAT), (iv) Going-live. …”
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2277
Antioxidative and anticancer effects of Tacca chantrieri extract enhancing cisplatin sensitivity in cholangiocarcinoma cells.
Published 2025-01-01“…TC treatments reduce CCA cell viability, inhibiting growth and inducing apoptosis in a dose-dependent manner. The Bax/Bcl-2 ratio increases, signifying a pro-apoptotic shift. …”
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2278
The Experience of Embodiment Scale: An examination of its psychometric properties in women from the Republic of Cyprus.
Published 2024-01-01“…Our work highlights important psychometric issues relating to the manner in which the EES should (or could) be conceptualised and modelled, which should be considered more fully in future work.…”
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2279
Building a Framework for Visual Question Answering Systems
Published 2025-01-01“…The significance of these systems lies in their ability to interpret and analyze images in a manner similar to human comprehension, making them applicable to a wide range of critical fields. …”
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2280
Network Pharmacology Analysis and Experimental Validation to Explore the Anti-inflammatory Mechanism of Asiatic Acid on Alcoholic Steatohepatitis
Published 2022-01-01“…The inflammatory factor tumor necrosis factor alpha (TNF-α), interleukin 1 beta (IL-1β), and interleukin 6 (IL-6) in a dose-dependent manner were decreased. In addition, hematoxylin-eosin staining showed that liver tissue damage and inflammatory cell infiltration in mice were significantly reduced with increasing doses. …”
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