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2221
Integration of ordered porous materials for targeted three-component gas separation
Published 2025-01-01“…Abstract Separation of multi-component mixtures in an energy-efficient manner has important practical impact in chemical industry but is highly challenging. …”
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2222
Malathion-Induced Hematoxicity and Its Recovery Pattern in Barbonymus gonionotus
Published 2021-01-01“…Except in the case of the control group (0% of malathion), the obtained results revealed that malathion exposure resulted in significantly (p<0.05) higher prevalence and severity of micronucleus and lower values of Hb, PCV, and RBC and significantly higher values of WBC in a concentration- and time-dependent manner. The values of blood glucose, MCV, MCH, and MCHC showed mixed trends during the experiment. …”
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2223
Modulation of Preactivation of PPAR-β on Memory and Learning Dysfunction and Inflammatory Response in the Hippocampus in Rats Exposed to Global Cerebral Ischemia/Reperfusion
Published 2012-01-01“…These effects were significantly improved by pretreatment with GW0742 in the dose-dependent manner. The expressions of IL-1β, IL-6, and TNF-α were increased after GCIRI, while the increases in these proinflammatory cytokines by GCIRI were inhibited by GW0742 pretreatment. …”
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2224
PARP inhibition-associated heterochromatin confers increased DNA replication stress and vulnerability to ATR inhibition in SMARCA4-deficient cells
Published 2025-01-01“…Interestingly, SMARCA4 deficient cells, intrinsically vulnerable to replication stress, exhibited exacerbated DNA damage upon combined ATRi and PARPi treatment in a Mre11- and Mus81-mediated manner. In vivo, combined treatment with intermittent ATRi and continuous PARPi showed greater inhibition of tumor growth than ATRi alone in SMARCA4-deficient lung adenocarcinoma xenograft models. …”
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2225
Low-Resolution Target Detection with High-Frequency Information Preservation
Published 2024-12-01“…It is composed of two key components: (1) the decoupled high-frequency learning component, which extracts the high-frequency information along the vertical and horizontal directions separately, and (2) the dilated frequency-aware channel correlation component, which decomposes the input feature map into multiple smaller ones in a dilated manner, concatenates them by channel, and then correlates the combined channels in the frequency space. …”
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2226
Aroma profile of two commercial truffle species from Yunnan and Sichuan, China: inter- and intraspecific variability and shared key compounds
Published 2021-03-01“…Furthermore, truffles of different provenance had distinct proportions of volatile constituents, suggesting that, besides genetic factors, edaphic and microclimatic conditions influence the synthesis of VOCs in a complex manner.…”
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2227
Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
Published 2025-01-01“…The enzyme exhibits promiscuity, processing various cyclic dipeptides as substrates in a distributive manner. The reaction is optimal at high pH and involves the formation of a radical intermediate. …”
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2228
Physicochemical Characterization of Star Anise Silver Nanoparticles Incorporated Chitosan Biomaterial for Absorb Water and Cure Wounds
Published 2022-01-01“…The anti-inflammatory assay suggests that nanoparticles prevent the aggregation of proteins in a dose-dependent manner. IC50 was found to be 20 μg/ml. The synthesized nanoparticle was incorporated into the chitosan biomaterial and characterized by various physicochemical parameters such as differential scanning calorimetry, scanning electron microscopy, FTIR, and thermogravimetric analysis. …”
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2229
Early Differentiation of Human CD11c+NK Cells with γδ T Cell Activation Properties Is Promoted by Dialyzable Leukocyte Extracts
Published 2016-01-01“…Thus, by direct effect on progenitor cells and through activation and remodeling of the supporting hematopoietic microenvironment, DLE may contribute a robust innate immune response by promoting the emerging lymphopoiesis of functional CD11c+ NK cells in a partially TLR-related manner. Unraveling the identity and mechanisms of the involved DLE components may be fundamental to advance the NK cell-based therapy field.…”
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2230
Network Diffusion Framework to Simulate Spreading Processes in Complex Networks
Published 2024-09-01“…For instance, by utilising these advancements, one can model structures such as social networks in a much more refined manner, which is particularly relevant in simulations of the spreading processes. …”
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2231
A Role of Fluoride on Free Radical Generation and Oxidative Stress in BV-2 Microglia Cells
Published 2012-01-01“…Activities of NOS in cells and medium significantly increased with fluoride concentrations in a dose-dependent manner. NT concentrations also increased significantly in 10 and 50 mg/L NaF-treated cells compared with the control cells. …”
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2232
Sparse Gene Coexpression Network Analysis Reveals EIF3J-AS1 as a Prognostic Marker for Breast Cancer
Published 2018-01-01“…EIF3J-AS1 may function in an estrogen-independent manner and could be inhibited by the compound FDI-6. …”
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2233
The protein circPETH-147aa regulates metabolic reprogramming in hepatocellular carcinoma cells to remodel immunosuppressive microenvironment
Published 2025-01-01“…Mechanistically, circPETH-147aa, encoded by circPETH in an m6A-driven manner, promotes PKM2-catalyzed ALDOA-S36 phosphorylation via the MEG pocket. …”
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2234
Landscape risk analysis of the 2003 Barkal-Rangamati (5.7 Mw) earthquake in Bangladesh using geospatial techniques and people’s perceptions
Published 2025-12-01“…Our detailed results will ultimately help the planners to assess better the changing state of 2003 Barkal-Rangamati earthquake-prone areas in a sustainable manner.…”
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2235
Effect of BMP-2 Delivery Mode on Osteogenic Differentiation of Stem Cells
Published 2017-01-01“…And also, we selected Arg-Gly-Asp- (RGD-) conjugated alginate hydrogel for BMP-2 delivery because alginate is able to release BMP-2 in a sustained manner and it is a biocompatible material. After 7 days of culture, the bottom-up release system in culture plate significantly stimulated alkaline phosphate activity of human bone marrow-mesenchymal stem cells. …”
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2236
Unveiling Tissue‐Specific RNA Landscapes in Mouse Organs During Fasting and Feeding Using Nanopore Direct RNA Sequencing
Published 2025-02-01“…Moreover, nanopore DRS revealed dynamic changes in poly(A) tail length and m6A modifications of transcripts, many regulated in a tissue‐specific manner. These changes likely contribute to functional differentiation and metabolic specialization of various organs. …”
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2237
Understanding pre-service teachers' intention to adopt and use artificial intelligence in Nigerian inclusive classrooms
Published 2025-02-01“…Technological self-efficacy did, however, have a significant positive and indirect contribution to the effect of performance expectancy and social influence on the pre-service teachers' behavioral intention to adopt and use AI for inclusive education teaching, based on their technological self-efficacy.DiscussionThe implication of findings of this study points to the exigency of a need to strengthen institutional policies and teacher preparation curricula in a manner that would advance the infusion of the use of artificial intelligence for teaching of learners with special needs.…”
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2238
Beneficial effects of AOS-iron supplementation on intestinal structure and microbiota in IDA rats
Published 2021-01-01“…After 4 weeks of AOS-iron supplementation, the fecal iron content of IDA rats markedly increased in a dose-dependent manner, only the damaged cecum and colon tissues in medium-dose (MD) and high-dose (HD) groups were repaired to the baseline, while the diversity of gut microbiota was improved even at low dose (LD). …”
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2239
Biological activity produced by ruthenium chloride on perfusion pressure, left ventricular pressure and heart failure using an isolated rat heart model
Published 2024-07-01“…Results: The results showed that ruthenium chloride increased the perfusion pressure from 1 to 100 nM; ruthenium chloride increased LVP in a dose-dependent manner, whose effect was inhibited by prazosin and WB-4101; and the ruthenium derivative significantly decreased the infarct area (p = 0.05) compared with the control conditions. …”
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2240
Performing Plurality: Meet the Alters Vlogs on YouTube as Breeding Grounds for Epistemic Justice
Published 2024-12-01“…The analysis highlights how plural YouTubers create their own hermeneutic resources to present their potentially unfamiliar or unruly experiences in an understandable manner to their viewers. In conversation with emerging and growing plural communities, these hermeneutic resources have been continually supplemented and refined. …”
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