Anti-cancer activity of synthetic gefitinib-1,2,3-triazole derivatives against Hela cells via induction of apoptosis by Zhihong Hu, Xixi Hou, Yongjing Ren, Ziyuan Wu, Dong Yan, Hong Chen, Lan Wang

“…Moreover, compound c13 significantly inhibited the colony formation ability of Hela cells in a dose-dependent manner, accompanied by morphological changes in HeLa cells. …”
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Domperidone inhibits dengue virus infection by targeting the viral envelope protein and nonstructural protein 1 by Nuttapong Kaewjiw, Thanawat Thaingtamtanha, Damini Mehra, Wanida Chawnawa, Tanapan Prommool, Chunya Puttikhunt, Adisak Songjaeng, Kessiri Kongmanas, Panisadee Avirutnan, Prasit Luangaram, Chatchawan Srisawat, Sittiruk Roytrakul, Stephan A. Bäurle, Sansanee Noisakran

“…Treatment of immortalized human hepatocyte-like cells (imHC) with domperidone could inhibit DENV production and NS1 secretion in a dose-dependent manner following infection with DENV serotype 2. These inhibitory effects were mediated by reduction in viral RNA replication and viral E and NS1 protein expression, but not by interference with virus entry into cells or NS1 oligomerization. …”
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Characteristics and treatment modes of industrial wastewater in new energy vehicles industrial park by LI Dian, WANG Xun, LIU Yingming

“…Each region needed to conduct water quality and quantity analysis in advance based on the current situation and development plans of the park, and dispose key pollutants in a targeted manner. At the same time, more consideration should be given to investment promotion, enterprise wastewater supervision, and wastewater treatment fees in the park.…”
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Key Intelligent Pesticide Prescription Spraying Technologies for the Control of Pests, Diseases, and Weeds: A Review by Kaiqiang Ye, Gang Hu, Zijie Tong, Youlin Xu, Jiaqiang Zheng

“…The advancement of these technologies will enhance agricultural productivity in a more efficient, environmentally sustainable manner.…”
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Comparison of the Pharmacological Effects of Paricalcitol and Doxercalciferol on the Factors Involved in Mineral Homeostasis by J. Ruth Wu-Wong, Masaki Nakane, Gerard D. Gagne, Kristin A. Brooks, William T. Noonan

“…In pig parathyroid cells, paricalcitol and the active form of doxercalciferol induced VDR translocation from the cytoplasm into the nucleus, suppressed PTH mRNA expression and inhibited cell proliferation in a similar manner, although paricalcitol induced the expression of CaSR mRNA more effectively. …”
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Traditional Chinese Medicine Improves Activities of Daily Living in Parkinson's Disease by Weidong Pan, Shin Kwak, Yun Liu, Yan Sun, Zhenglong Fang, Baofeng Qin, Yoshiharu Yamamoto

“…Patients took either ZAZ2 (𝑛=59) or placebo granule (𝑛=56) in a blind manner for 13 weeks while maintaining other anti-Parkinson medications unchanged. …”
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Syringaldehyde Alleviates Cardiac Hypertrophy Induced by Hyperglycemia in H9c2 Cells Through GLP-1 Receptor Signals by Yingxiao Li, Chao-Tien Hsu, Ting-Ting Yang, Kai-Chun Cheng

“…<b>Results:</b> SA reduced cell size and hypertrophic biomarkers in a dose-dependent manner while increasing GLP-1 receptor expression and cAMP levels. …”
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Explanation of Water Indices and Criteria in the Urban Landscape in Order to Improve the Quality of Urban Environments by Zeynab khaleghi, Farah Habib, Hossein Zabihi

“…The use of water criteria and indicators in the urban landscape in a coherent and integrated manner requires a compiled pattern that is presented in the end in a tabular form.…”
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Transcriptome-Based Modeling Reveals that Oxidative Stress Induces Modulation of the AtfA-Dependent Signaling Networks in Aspergillus nidulans by Erzsébet Orosz, Károly Antal, Zoltán Gazdag, Zsuzsa Szabó, Kap-Hoon Han, Jae-Hyuk Yu, István Pócsi, Tamás Emri

“…AtfA acts in a stress-specific manner, which may increase further the number and diversity of AtfA-dependent genes. …”
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Effect of TIPA on Chloride Immobilization in Cement-Fly Ash Paste by Baoguo Ma, Ting Zhang, Hongbo Tan, Xiaohai Liu, Junpeng Mei, Wenbin Jiang, Huahui Qi, Benqing Gu

“…The formation of Friedel’s salt in hydration process is widely accepted as an effective manner for this hindrance. In this study, an attempt to hasten the formation of Friedel’s salt by adding triisopropanolamine (TIPA) was done in the cement-fly ash system, with intention to chemical bind chloride, and the chloride-binding capacity at 60 d age was examined. …”
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A novel knowledge distillation framework for enhancing small object detection in blurry environments with unmanned aerial vehicle-assisted images by Sayed Jobaer, Xue-song Tang, Yihong Zhang, Gaojian Li, Foysal Ahmed

“…Following this, we employ a technique known as self-supervised knowledge distillation, where we introduce a deblurring subnet module with the help of two attention modules, where both networks are trained in a fully-supervised manner. Based on the experiment results, our proposed model achieves an improvement of 4.3% accuracy in the VisDrone synthetic motion blur dataset and 4.6% in detecting objects within synthetic blurry images in our developed small object detection dataset (SOD-Dataset), as well as competitive results compared with other state-of-the-art methods. …”
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Towards a sustainable set of European Core Health Indicators (ECHI) by Mariken J. Tijhuis, Eveline A. van der Wilk, Sarka Dankova, Angela Fehr, Silvia Ghirini, Mika Gissler, Romana Haneef, Heidi Lyshol, Emanuele Scafato, Stefanie Seeling, Hanna Tolonen, Thomas Ziese, Irisa Zīle-Velika, Peter W. Achterberg

“…This cannot be achieved in a non-systematic project-based manner; it requires sustainable funding, governance and formalised activities in a permanent structure. …”
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Th17: A New Participant in Gut Dysfunction in Mice Infected with Trichinella spiralis by Yu Fu, Wenfeng Wang, Jingjing Tong, Qi Pan, Yanqing Long, Wei Qian, Xiaohua Hou

“…When jejunual smooth muscle strips were cultured with IL-17, contractions elicited by Ach were enhanced in a concentration-dependent manner. Our data suggest that Th17 cells are increased during acute infection with Trichinella spiralis and IL-17 may contribute to jejunal muscle contractility in mice.…”
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Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes by Richard G. Peterson, Charles V. Jackson, Karen Zimmerman, Willem de Winter, Norman Huebert, Michael K. Hansen

“…The ZDSD rat develops prediabetic metabolic syndrome and T2D in a manner that mirrors the development of metabolic syndrome and T2D in humans. …”
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Calorie Labeling in a Rural Middle School Influences Food Selection: Findings from Community-Based Participatory Research by Monica Hunsberger, Paul McGinnis, Jamie Smith, Beth Ann Beamer, Jean O’Malley

“…Students in grades 6–8, dining at the school cafeteria January and February 2010, participated for 17 school days each month; in January a menu was offered in the usual manner without calorie labels; the same menu was prepared in February with the addition of calorie labels at point-of-purchase. …”
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Simplified Lawsuits in Dispute Resolution Within Sharia Economic Law in Indonesia by Dadin Solihin, Setiadi Setiadi, Bubun Bunyamin, Deni Kamaludin Yusup, Ahmad Hasan Ridwan

“…The Regulation of the Supreme Court of the Republic of Indonesia (PERMA RI) No. 4 of 2019 regulates the resolution of Sharia economic law disputes in a simplified manner. However, the socialization of this regulation to the public is still lacking, causing frequent obstacles in the implementation of this PERMA RI. …”
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Characterization of the Sodium Multi-Vitamin Transporter in the Mosquito <i>Anopheles stephensi</i> and Its Capacity to Mobilize Pantothenate and Biotin by Jun Isoe, Brendan F. Riske, Megan E. Dobson, Hannah L. Kaylor, Jessica C. Brady, Yared Debebe, Laura M. Saavedra, Shirley Luckhart, Michael A. Riehle

“…We demonstrated that this transporter is capable of mobilizing both Pan and biotin (vitamin B7) in a dose dependent manner. We also assessed the distribution of <i>A. stephensi</i> sodium multi-vitamin transporter in the mosquito and its capacity to transport vitamins. …”
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A high-valence bismuth(V) nanoplatform triggers cancer cell death and anti-tumor immune responses with exogenous excitation-free endogenous H2O2- and O2-independent ROS generation by Yizhang Tang, Xujiang Yu, Liangrui He, Meng Tang, Wenji Yue, Ruitong Chen, Jie Zhao, Qi Pan, Wanwan Li

“…Here we report a versatile oxidizing pentavalent bismuth(V) nanoplatform (NaBiVO3-PEG) can generate reactive oxygen species in an excitation-free and H2O2- and O2-independent manner. Upon exposure to the tumor microenvironment, NaBiVO3-PEG undergoes continuous H+-accelerated hydrolysis with •OH and 1O2 generation through electron transfer-mediated BiV-to-BiIII conversion and lattice oxygen transformation. …”
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Study on the mechanical behavior of corroded bridge steel based on the entire process of tensile failure by Yi Li, Dapeng Hu, Yangming Xu, Bo Wang, Yongjun Zhou, Zhonghong Dong

“…Assessing the health of corroded bridge steel structures under load conditions in a manner that avoids causing damage can effectively prevent these intensifying safety hazards. …”
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Effects of Transcranial Alternating Current Stimulation on Repetitive Finger Movements in Healthy Humans by Andrea Guerra, Matteo Bologna, Giulia Paparella, Antonio Suppa, Donato Colella, Vincenzo Di Lazzaro, Peter Brown, Alfredo Berardelli

“…These findings demonstrate that tACS modulates finger tapping in a frequency-dependent manner with no concurrent changes in corticospinal excitability. …”
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