The antitumor activity of umbelliferone in human renal cell carcinoma via regulation of the p110γ catalytic subunit of PI3Kγ by Wang Xue, Huang Shuaishuai, Xin Xia, Ren Yu, Weng Guobin, Wang Ping

“…Our results have revealed that treatment of human RCC cells (786-O, OS-RC-2, and ACHN) with umbelliferone reduced cell proliferation in a concentration-dependent manner and induced dose-dependent apoptotic events. …”
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Exosome Loaded in Microneedle Patch Ameliorates Renal Ischemia–Reperfusion Injury in a Mouse Model by Samin Taghavi, Somayeh Keshtkar, Mozhgan Abedanzadeh, Mehrdad Hashemi, Reza Heidari, Samira Sadat Abolmaali, Mahintaj Dara, Mahdokht Hossein Aghdaei, Alireza Sabegh, Negar Azarpira

“…Conclusion: The use of a microneedle patch containing exosomes is a noninvasive method that enables the release of exosomes in a slow manner. In comparison to exosome injection alone, microneedle patch-exosome treatment offers a longer and more targeted effect that improves renal IRI dysfunction and reduces tissue damage, potentially facilitating the clinical application of exosomes and improving graft survival.…”
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The space of Henstock integrable functions of two variables by Krzysztof Ostaszewski

“…We show by an example that the dual can't be described in a manner analogous to the one-dimensional case, since in two variables there exist functions whose distributional partials are measures and which are not multipliers for Henstock integrable functions.…”
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Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich Bases by B. Anil Reddy

“…The various positions on the benzimidazole ring are numbered in the manner indicated with the imino function as number one. …”
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‘For God’s Sake Look at This!’: Physiognomy in Bleak House by Michael Hollington

“…I survey the successful observers of physiognomy in the novel, such as Esther and Woodcourt, and what they observe—not just faces but ’manner’ or ’body language.’ I also explore the physiognomy of things, as this builds into a formidable indictment of the face of Victorian society.…”
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Assessing urban resilience and sustainability in the face of natural hazards with emphasis on reducing vulnerability in cities (Case study: Semnan city) by mozaffar mohamadkhani, zeynab karke abadi, abbas arghan

“…In the desired situation, a resilient city has a strong local society with a dynamic and sustainable economy that is governed institutionally and institutionally in a participatory manner. As a result of these super-physical factors, the city is formed in a cohesive manner and no withering is observed at any point. …”
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Cervical Spondylotic Myelopathy Secondary to Dropped Head Syndrome: Report of a Case and Review of the Literature by Abolfazl Rahimizadeh, Housain F. Soufiani, Saghayegh Rahimizadeh

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The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming by Bharathi Suresh, Junwon Lee, Kye-Seong Kim, Suresh Ramakrishna

“…Ubiquitination and deubiquitination must occur in a timely and well-coordinated manner to regulate the protein turnover of several stemness related proteins, resulting in optimal embryonic stem cell maintenance and differentiation. …”
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GEOPOLITICAL VARIATION IN THE REPORTAGE OF SECURITY BY THE NATION AND DAILY TRUST NEWSPAPERS (2010-2020): A PROGNOSIS by M. M. NURUDDEN, M. M. NURUDDEN

“…The two national dailies are expected to be nationalistic and report security issue in an objective manner instead of framing narratives that can exacerbate tension. …”
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Intelligent Early Warning System for Construction Safety of Excavations Adjacent to Existing Metro Tunnels by Wei Tian, Jiang Meng, Xing-Ju Zhong, Xiao Tan

“…However, these methods make it difficult to enact effective control measures in a timely manner owing to the lag of information processing. …”
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Fine-Tuned Spin-3/2 and the Hierarchy Problem by Ozan Sargın

“…In this work, a spin-3/2 particle has been used in the same manner to nullify the power-law divergences, and it is determined that the mass of the spin-3/2 particle resides in the ball park of the GUT scale.…”
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La Montagne dans l’œuvre de quelques écrivains libanais d’expression anglaise by Jacqueline Jondot

“…Lebanese writers in the English language represent their mountains in an ambivalent manner: they use western aesthetic concepts (sublime, picturesque) while setting their representation in an Eastern context of ideological reappropriation of their land, focusing on its cultural and human occupation with a strong opposition between mountain and city dwellers. …”
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Scalp-Ear-Nipple Syndrome: A Case Report by Estela Morales-Peralta, Vivian Andrés, Dainé Campillo Betancourt

“…It is concluded that SEN syndrome should be recognized as an entity with genetic heterogeneity once there is evidence of different genetic manner of inheritance described in this disease.…”
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Α Byzantine icon of the Theotokos Hodegetria (Temple Gallery, London) by Triviza Eleni

“…The depiction of the Virgin Mary in half-length, turning to the right, with her gaze fixed on the viewer, the manner of the depiction and attitude of Jesus Christ, the rendering of their facial features, the imposingness of the two figures and their movements, the pleats of the clothes and the configuration of the two halos indicate the work of a highly skilled painter. …”
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Recent advances in electrochemical copper catalysis for modern organic synthesis by Yemin Kim, Won Jun Jang

“…Combining electrochemistry with transition-metal catalysis is a promising and rapidly growing methodology for effectively forming challenging C–C and C–heteroatom bonds in complex molecules in a sustainable manner. In this review, we summarize the recent advances in the combination of electrochemistry and copper catalysis for various organic transformations.…”
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The Wedgworth Leadership Institute for Agriculture and Natural Resources by Hannah Carter, Rochelle Strickland

“…These leaders are prepared to become increasingly involved in forming policies that affect the future of Florida agriculture and natural resources in a direct or indirect manner. This 2-page fact sheet was written by Hannah Carter and Rochelle Strickland, and published by the UF Department of Agricultural Education and Communication, October 2012. …”
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Asymptotic modeling of viscoelastic thin plates and slender beams, a unifying approach by Terapabkajornded, Yotsawat, Orankitjaroen, Somsak, Licht, Christian, Weller, Thibaut

“…We show that this framework makes it possible to perform the asymptotic analysis for both viscoelastic thin plates and slender beams in a unifying manner. Several models are provided for the dynamic behavior of such structures in bilateral contact with a rigid body on a part of their boundaries with Norton or Tresca friction.…”
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The Wedgworth Leadership Institute for Agriculture and Natural Resources by Hannah Carter, Rochelle Strickland

“…These leaders are prepared to become increasingly involved in forming policies that affect the future of Florida agriculture and natural resources in a direct or indirect manner. This 2-page fact sheet was written by Hannah Carter and Rochelle Strickland, and published by the UF Department of Agricultural Education and Communication, October 2012. …”
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A Real-Time and Closed-Loop Control Algorithm for Cascaded Multilevel Inverter Based on Artificial Neural Network by Libing Wang, Chengxiong Mao, Dan Wang, Jiming Lu, Junfeng Zhang, Xun Chen

“…In order to control the cascaded H-bridges (CHB) converter with staircase modulation strategy in a real-time manner, a real-time and closed-loop control algorithm based on artificial neural network (ANN) for three-phase CHB converter is proposed in this paper. …”
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Evaluation of anticancer potency of Cu-isatin-1-(2-pyridyl) piperazine thiosemicarbazone (Cu-Istpypz) against epidermoid carcinoma cell line (A431) by Indranil Banerjee, Piyush Kumar, Narendra K. Singh, Paras N. Yadav, Yuba Raj Pokharel

“…The compound Cu-Istpypz also suppressed the colony formation of A431 cells in a concentration-dependent manner, as demonstrated by the clonogenic assay. Additionally, at higher concentrations, Cu-Istpypz slowed down the migration and wound-healing capabilities of A431 cells. …”
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