Association between Alpha- Klotho Protein, Calcium, and Phosphate concentrations in Adult Iraqi Patients with Beta-Thalassemia Major by Ahmed J. Kadhim, Hedef D. El-Yaseen, Ali M. Jawad

“…Alpha-Klotho protein is a protein that has anti-aging properties and is involved in several functions, including reducing oxidative stress, regulating energy metabolism through several routes, and managing calcium and phosphate metabolism. Objective: This study aimed to assess changes in calcium and phosphate levels, Alpha-Klotho protein concentration, and their associations with cardiac dysfunction in patients with Beta-thalassemia major. …”
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Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity by Wen-lin Pang, Wen-lin Pang, Tian-gang Li, Tian-gang Li, Yin-ying Wang, Yin-ying Wang, Li-yun Song, Li-yun Song, Li Li, Li Li, Xiao-ya Li, Xiao-ya Li, Yong Qiu, Yong Qiu, Zhong-shan Yang, Zhong-shan Yang

“…In addition, analysis of 16S rRNA gene sequencing indicated that SC reduced harmful bacterial populations, such as Proteobacteria, while simultaneously enhancing the levels of beneficial bacteria like Lactobacillus, thereby contributing to the improvement of UC pathology.ConclusionThis study highlights the therapeutic potential of SC in managing UC through its ability to attenuate inflammatory responses, restore intestinal barrier functionality, and modulate gut microbiota composition, which findings offer insights into potential strategies for advancing UC treatment.…”
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Fuzzy Logic Recommender Model for Housing by Emanuel G. Munoz, Jaime Meza, Sebastian Ventura

“…The recommendation system relies on fuzzy control to manage user preferences and select appropriate input data with which to test the model. …”
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Transcatheter edge to edge compared with surgery in older patients with degenerative mitral valve regurgitation by Gaspard Suc, Rebecca Hadjedj, Jules Mesnier, Skerdi Haviari, Marylou Para, Gregory Ducrocq, Dominique Himbert, Eric Brochet, My Lien Nguyen, Sophie Provenchere, Marina Urena, Bernard Iung

“…Conclusion Patients with severe primary MR treated with TEER experienced a higher rate of adverse events within one year compared to surgically managed patients. However, these differences were mainly associated to clinical characteristics and were no longer significant after adjustment on residual MR > 2. …”
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Excessive Weight Gain During Pregnancy Increased Ponoxarase 1 Level in Neonatal Cord Blood by Serhat Ege, Hasan Akduman, Ayşegül Aşır, Tuğcan Korak

“…Maternal obesity may specifically affect PON1 activity, potentially serving as a compensatory response to oxidative stress in neonates, suggesting PON1 as a possible biomarker for oxidative stress-related metabolic disturbances in neonates of obese mothers, with implications for monitoring and managing pregnancy outcomes in obese populations.…”
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Mapping the Gaps: A Scoping Review of Virtual Care Solutions for Caregivers of Children with Chronic Illnesses by Nicole Pope, Kathyrn A. Birnie, Melanie Noel, Justine Dol, Danyu Li, Megan Macneil, Darrel Zientek, Victoria Surry, Jennifer N. Stinson

“…Significant gaps were noted in interventions for managing caregiver chronic pain, despite its high prevalence and impact on child outcomes. …”
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CtBP1 is essential for epigenetic silencing of μ-opioid receptor genes in the dorsal root ganglion in spinal nerve ligation-induced neuropathic pain by Cheng-Yuan Lai, Ming-Chun Hsieh, Chou-Ming Yeh, Tzer-Bin Lin, Dylan Chou, Hsueh-Hsiao Wang, Kuan-Hung Lin, Jen-Kun Cheng, Po-Sheng Yang, Hsien-Yu Peng

“…Targeting the Foxp1/CtBP1/HDAC2/μ-opioid receptor signaling pathway in the DRG holds promise as a potential therapeutic strategy for managing neuropathic pain.…”
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Structural performance of lightweight fibre-reinforced oil palm shell concrete subjected to impact loadings under varying boundary conditions by Idris Ahmed Ja'e, Zakaria Che Muda, Agusril Syamsir, Chiemela Victor Amaechi, Hamad Almujibah, Ali.E.A. Elshekh, Maaz Osman Bashir, Abdulrazak H. Almaliki

“…This innovative approach aims to mitigate environmental pollution and promote sustainable practices in managing industrial waste. Despite these benefits, there is a limited study on the structural behaviour of lightweight oil palm shells (OPS) concrete with varying boundary conditions. …”
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Optimized reinforcement of granite residual soil using a cement and alkaline solution: A coupling effect by Bingxiang Yuan, Jingkang Liang, Baifa Zhang, Weijie Chen, Xianlun Huang, Qingyu Huang, Yun Li, Peng Yuan

“…The study provides an analysis of strategies for mitigating and managing GRS slope failures, as well as enhancing roadbed performance.…”
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Impact of Treatment on Rate of Biphasic Reaction in Children with Anaphylaxis by William Bonadio, Connor Welsh, Brad Pradarelli, Yunfai Ng

“…Methods: We reviewed consecutive children diagnosed with acute anaphylaxis managed in three EDs during a six-year period. All received IM EPI and CS, followed by monitoring for 4–6 hours post-treatment. …”
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Diurnal and daily fluctuations in levels of the urinary oxidative stress marker 8-hydroxyguanosine in spot urine samples by Yun-Shan Li, Koichi Fujisawa, Kazuaki Kawai

“…Urinary 8-OHGuo could serve as a valuable biomarker for managing and preventing oxidative stress–related diseases, provided that the specific range of daily variations is established. …”
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Optimal sizing and performance assessment of stand-alone PV systems using optimum hybrid sizing strategy by Mohamad Abed, Amarendra Reddy B, T.R. Jyothsna, Nabil Mohammed

“…Since individual optimization methods for SAPVS sizing aim to address multipurpose challenges, the hybrid approach effectively manages such complexities. This strategy is developed by integrating three stages. …”
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The Effort to Rationalize Antibiotic Use in Indonesian Hospitals: Practice and Its Implication by Selma Siahaan, Rukmini Rukmini, Betty Roosihermiatie, Pramita Andarwati, Rini S. Handayani, Ingan U. Tarigan, Tita Rosita, Rustika Rustika, Yuslely Usman, Lusi Kristiana

“…Informants at the hospitals were hospital directors, chairmen of the AMR-CP team, chairmen of the medical committee, persons in charge of the microbiology laboratory, clinicians, nurses, clinical pharmacists, and those program managers at the provincial health offices who are responsible for administering antibiotics. …”
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Conventional endotracheal tubes versus polymer-coated tubes in ventilator-associated pneumonia development: A systematic review and meta-analysis by Oscar Inácio de Mendonça Bisneto, Luanna Paula Garcez de Carvalho Feitoza, Larissa Calixto Hespanhol, Sávio Benvindo Ferreira, Caroline Serafim Dagostin, Roberto Augusto Mazetto Silva Vieira, Lucas Alencar Queiroz, Lucas Chen, Taniela Marli Bes, Ho Yeh Li

“…Statistical analysis was performed using Review Manager Software, and a The Mantel-Haenszel test was performed using a random effects model, and risk ratios (RR) were calculated for binary outcomes. …”
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Comparative safety and effectiveness of cryoballoon versus radiofrequency ablation for atrial fibrillation: a systematic review and meta-analysis by Muhammad Furqan, Ifrah Inbisat Raza, Shaheera Younus, Hareer Fatima, Hiba Azhar, Sania Kaneez Fatima, Laiba Ali, Sara Khan, Aayat Ellahi

“…However, another technique known as cryoballoon ablation (CBA) has been developed as another option for managing this heart rhythm disorder. This study evaluated the efficacy and safety of CBA and RFCA for the treatment of AF. …”
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Risk factors for renal insufficiency and survival implications after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: a systematic review by Zhigao Huang, Zhuo Liu, Lin Zhuo, Xin Ma, Zhenbin Jiang, Kewei Chen, Jiyuan Chen, Yuxuan Li, Guoliang Wang, Xiaojun Tian, Hongxian Zhang, Lei Liu, Lulin Ma, Kai Hong, Shudong Zhang

“…A clear association between survival and renal function could not be established because of the oncological risk on survival. Necessary managements like supplying blood volume, diuretic therapy and renal replacement therapy should be applied. …”
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Comparison of Hybrid Rye and Wheat for Grain Yield and Other Agronomic Traits Under Less Favourable Environmental Conditions and Two Input Levels by Thomas Miedaner, Sophie Lauenstein, Bärbel Lieberherr

“…The trial was grown for three years (2021, 2022, 2023) on three conventionally managed farms with 40–64 soil points (on a scale of 1–100) in south-west Germany. …”
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Clinical evaluation of 3D PEEK implants for skull bone defects repair: a single center case serious by Mohamed Ahmed Elnaggar, Hossam Abdelhakim Elnoamany, Mohamed K. Eissa

“…Conclusion 3D-printed PEEK implants provide a feasible and effective solution for skull bone defect repair, with favorable outcomes and manageable complication rates. These custom implants offer a personalized approach to cranioplasty, but larger studies with longer follow-up are needed to validate these findings.…”
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Socioeconomic position and breast cancer screening use in Chile: A population-based study by Camilo Guerrero-Nancuante, Pamela Eguiguren, Isabel Abarca-Baeza, Isabel Guzmán, María Luisa Garmendia

“…Ref: quintile V) and being unemployed (Prevalence ratio = 1.34; 95 % CI 1.18–1.51) or working in service and commerce (Prevalence ratio = 1.21; 95 % CI 1.06–1.39) (Ref: Managers and professionals). Conclusions: Low SEP was significantly associated with the non-use of mammography. …”
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Perception of undergraduate emergency medical services students about mental health by Abdullah Alruwaili, Ahmed Alanazy, Fatimah Alyousif, Kawthar Alnajjad, Asrar Alali

“…With a total of 83 participants, averaging 21.33 years old, from three regions in Saudi Arabia, we found significant differences in the following questions before and after the mental health block: participants became more comfortable managing mental health issues (strongly agreeing increased from 10.8% to 36.1%). …”
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