Neoadjuvant apatinib addition to sintilimab and carboplatin-taxane based chemotherapy in patients with early triple-negative breast cancer: the phase 2 NeoSAC trial by Guoshuang Shen, Zhilin Liu, Miaozhou Wang, Yi Zhao, Xinlan Liu, Yujin Hou, Wenbiao Ma, Jingqi Han, Xiaofeng Zhou, Dengfeng Ren, Fuxing Zhao, Zitao Li, Shifen Huang, Yongzhi Chen, Yingjian He, Yan Liu, Zijun Zhu, Yongxin Li, Jinming Li, Mengting Da, Hongnan Mo, Feng Du, Liang Cui, Jing Bai, Zhen Liu, Fei Ma, Jiuda Zhao

“…Our study suggests that apatinib, sintilimab combined with carboplatin and nab-paclitaxel chemotherapy showed a promising clinical activity and manageable safety profile in early TNBC and merits further study. …”
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A Study to Determine the Mediating Effect of Novelty Seeking in the Effect of Consumers’ Personal Values on Attitudes Towards Functional Foods by Selçuk Efe Küçükkambak

“…In the light of the data obtained within the scope of the research, some inferences were made to the marketing managers and suggestions were presented to the researchers for future studies. …”
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Impact of Exercise on Tramadol-Conditioned Place Preference by Haneen Amawi, Alaa M. Hammad, Aseel Abdullah Ibrahim, Nosyba Alsbih, Frank Scott Hall, Fawaz Alasmari, Bahaa Al-Trad

“…Background: Tramadol (TRA) is an opioid that is used to manage moderate to severe pain. Long-term use of TRA can lead to the development of opioid use disorder. …”
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An Improved Solar Cooling System for Date Safety and Storage under Climate of the Maghreb by Benameur Afif, Boualem Merabet, Mustafa Inc, Younes Menni, Sameer Alsharif, Ahmed Althobaiti, Ayman A. Aly

“…As a freely available energy source for managing long-term issues in energy crisis, solar energy (SE) will have to grow more to meet world’s energy demands. …”
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Relationship between muscle activation and sagittal knee joint biomechanics in patients with patellofemoral pain syndrome: a cross-sectional study by Byung Sun Choi, Soon Bin Kwon, Sehyeon Jeon, Myeongjun Kim, Yunseo Ku, Du Hyun Ro, Hyuk-Soo Han

“…Conclusions Patients with PFPS exhibit elevated muscle activation, particularly in response to changes in the knee extension moment, which is likely a compensatory mechanism to manage knee joint loading during gait. These results highlight altered neuromuscular adaptations in PFPS, suggesting targeted therapies may help improve functional outcomes. …”
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PREDISPOSITION FACTORS ANALYSIS FOR FOURNIER'S GANGRENE DEFECTS CLOSURE COMPLICATION by Bayu Fasi Bermani, Sitti Rizaliyana, Ira Handriani

“…The study aims to share our policy in managing Fournier's gangrene and identifying risk factors that can affect the outcome of defect closure. …”
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The safety and effectiveness of tDCS for epileptic patients: A systematic review and meta-analysis by Xiao-Tong Ding, Ming-Yu Hu, Chi Wang, Wei-Ye Kang, Jin-Zhao Huang, Rui-Yu Wang, Qiu-Song Shen, Hou-Ming Kan

“…The meta-analysis was conducted using Review Manager 5.4 software. Results: 12 trials were included, 356 participants (219 in the tDCS group and 137 in the sham group). …”
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Impacts of survey design on a Gulf of Mexico bottom longline survey and the transition to a unified, stratified - random design by Jill M. Hendon, Eric R. Hoffmayer, Adam G. Pollack, John Mareska, Fernando Martinez-Andrade, Jeff Rester, Theodore S. Switzer, Zachary C. Zuckerman

“…Size composition was compared for three managed species. The size composition of Atlantic Sharpnose Sharks and Blacktip Sharks differed significantly between the modified SEAMAP BLL survey and the NMFS BLL survey, indicating that the modified survey is indeed providing complementary data. …”
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Diagnosis of naturally‐occurring Cushing's syndrome by primary care veterinarians in selected European countries by Miguel F. Carvalho, Rodolfo O. Leal, Stefania Golinelli, Federico Fracassi, Carolina Arenas, Maria Pérez‐Alenza, Sara Galac, Carmel T. Mooney, Michael Bennaim

“…Cases are rarely referred to a specialist, reflecting that Cushing's syndrome is mainly managed in primary care practices. These results suggest that there is room for further education of PCVs.…”
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Understanding regular exercise behavior in frail older adults: a structural equation model based on social-cognitive variables by Shiqi Yu, Jie Lin, Siping Song, Shuqi Huang, Fan Liu, Mingzhao Xiao

“…Abstract Background Regularly engaging in exercise has been recognized as the only therapy found to consistently manage frailty. This study applies structural equation modeling (SEM) to integrate the theoretical perspective of Social cognitive theory (SCT) to better understand and promote regular exercise behavior among frail older adults, providing a foundation for enhancing exercise engagement in this vulnerable population. …”
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Co-occurrence of entomopathogenic nematodes and earthworms enhances enduring biocontrol activity and microbial diversity in a naturalized plant-soil system by Maryam Chelkha, Rubén Blanco-Pérez, David Labarga, María de Toro, Jorge Dueñas-Hernani, Kyle Wickings, Raquel Campos-Herrera

“…EWs enhance soil health by improving aeration, porosity, and nutrient cycling, while EPNs, such as Steinernema and Heterorhabditis, manage pests by killing insects. This study aimed to assess the impact of EWs and their derivatives (cutaneous excreta, CEx), alone or combined with EPNs, on soil–plant dynamics, hypothesizing that their co-occurrence would alter soil properties, bacterial communities, EPN virulence, and plant performance. …”
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Heat transportation of 3D chemically reactive flow of Jeffrey nanofluid over a porous frame with variable thermal conductivity by Nahid Fatima, Aaqib Majeed, Taoufik Saidani, Nouman Ijaz, Kamal Barghout, Nidal Abu-Libdeh

“…These PDEs are subsequently simplified into more manageable ordinary differential equations (ODEs) using the similarity variables. …”
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An enigma of Malaysia's low-income young adults: Mediation of financial behaviour on financial well-being and locus of control cohesion. by Mohamad Fazli Sabri, Rozita Wahab, Nurul Shahnaz Mahdzan, Amirah Shazana Magli, Husniyah Abd Rahim, Siti Shazwani Ahmad Suhaimi, Nur Shuhamin Nazuri

“…The rising cost of living and unstable economies have impacted how they consume, manage, and save monthly income to maintain their standard of living. …”
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Central Diabetes Insipidus in Children and Adolescents: Twenty-Six Year Experience from a Single Centre by Hüseyin Anil Korkmaz, Ritika R Kapoor, Jennifer Kalitsi, Simon JB Aylwin, Charles R Buchanan, Ved Bhushan Arya

“…The clinic database was searched to identify patients with CDI managed between 1993 and 2019. Relevant clinical information was collected from patient records. …”
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Unveiling the psychosocial and academic implications of living with sickle cell disease among undergraduates in a private university in Nigeria by Olumide T. Adeleke, Olufemi Folaranmi, Yetunde Olasinde, Larry Ayuba, Oludamola V. Adeleke, Modupe M. Ojo-Rufai, Efeturi Agelebe, Oyelola E. Adeoye, Aderemi T. Olabode, Dolapo E. Ajala, Titilola S. Akingbola

“…The findings underscored the need for increased awareness, support, and understanding to better assist undergraduates with SCD in managing their health and academic responsibilities effectively. …”
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Anti-Biofilm Effect of Ampicillin-Loaded Poly (Lactic-co-glycolic Acid) Nanoparticles Conjugated with Lysostaphin on Methicillin-Resistant Staphylococcus aureus by Elahe Norouzi, Seyed Mostafa Hosseini, Babak Asghari, Reza Mahjoub, Ehsan Nazarzadeh Zare, Mohammad-Ali Shahbazi, Fereshte Kalhori, Mohammad Reza Arabestani

“…Given the excellent efficacy of the nanomedicine carrier established in the present study, applying this technology to combat hospital-acquired infections caused by Staphylococcus bacteria could yield significant benefits in managing staphylococcal infections.…”
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Improving the Utility, Safety, and Ethical Use of a Passive Mood-Tracking App for People With Bipolar Disorder Using Coproduction: Qualitative Focus Group Study by Laurence Astill Wright, Matthew Moore, Stuart Reeves, Elvira Perez Vallejos, Richard Morriss

“…Principally, people with BD wished to use this novel technology to aid them in self-managing their BD with greater insight and a better understanding of potential triggers. …”
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Unusual presentation of a patient with partial anomalous pulmonary venous connections without a septal defect: a case report and literature review by Pouya Ebrahimi, Mohammad Hossein Mandegar, Mehrdad Jafari Fesharaki, Negar Ghasemloo, Pedram Ramezani, Tooba Akbari, Fatemeh Naderi

“…Post-surgical cardiac overload caused pleural effusion and dyspnea, which were managed with diuretics. Four- and six-month follow-ups showed no abnormal findings on examination and imaging, and the patient reported no new complaints. …”
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What strategies are used to select patients for direct admission under acute medicine services? A protocol paper for a systematic review of the literature by Elizabeth Sapey, Catherine Atkin, Samuel Evans, Austin Hunt, Georgina Ball, Charlotte Cassidy, Alexander Costley-White, Louise Toy, Rebecca Wilding

“…It is suspected that there is a significant variation in how these patients are selected, triaged and managed in the UK. This systematic review will assess the methods and evidence base used for direct patient admissions to acute medicine services compared with traditional admission pathways through the emergency department.Methods and analysis A systematic review of the literature will be conducted and a total of six databases will be searched: MEDLINE (Ovid), The Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE in process, Web of Science, CINAHL and Embase. …”
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How can cervical screening meet the needs of vulnerable women? A qualitative comparative study with stakeholder perspectives from seven European countries by Partha Basu, Martin McKee, Adriana Băban, Marc Bardou, Ana Fernandes, Margarida Teixeira, Rebecca Moore, Nuno Lunet, David Ritchie, Romeu Mendes, Eric Lucas, Paolo Giorgi Rossi, Rosa Legood, Berit Andersen, Diana Taut, Keitly Mensah, João Firmino-Machado, Mariana Amorim, Mette Tranberg, Laura Bonvicini, Anneli Uusküla, Pia Kirkegaard, Paola Mantellini, Ines Baia, Liu Sun, Lise Rochaix, Camilla Fiorina, Luca Ghirotto, Anna Tisler, Firmino Machado, Rikke Buus Bøje, Raquel Rico Berrocal, Noemi Auzzi, Kerli Reintamm, Yulia Panayotova, Tatyana Kotzeva, Anna Foss, Rachel Greenley, Letizia Bartolini, Giusy Iorio, Cláudia Gouvinhas, Florian Nicula, Alexandra Tolnai, Vanessa Moore, Isabel Mosquera Metcalfe, Violette Delisle, Irina Todorova, Helena Ros Comesana, Meritxel Mallafré-Larrosa, Ginevra Papi, Nicoleta-Monica Pașca, Christiane Dascher-Nadel, Olivra Djuric

“…Data collection took place in Bulgaria, Denmark, Estonia, France, Italy, Portugal and Romania.Participants Represented stakeholders at various levels, including user representatives (vulnerable women), healthcare professionals, social workers, programme managers and decision makers.Methods 14 meetings lasting 2 hours each were held in these seven countries between October 2021 and June 2022. …”
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