Drp1–associated genes implicated in sepsis survival by Marissa D. Pokharel, Marissa D. Pokharel, Anlin Feng, Anlin Feng, Ying Liang, Ying Liang, Wenli Ma, Wenli Ma, Saurabh Aggarwal, Hoshang Unwalla, Stephen M. Black, Stephen M. Black, Stephen M. Black, Ting Wang, Ting Wang, Ting Wang

“…Therefore, there is a critical need for reliable prognostic markers to be used in clinical settings to improve the management and outcomes of patients with sepsis. Recent studies have suggested that mitochondrial dynamics, including the processes of mitochondrial fission and fusion, are closely related to the severity of sepsis and the status of inflammation. …”
Get full text

A cost-effectiveness analysis of sotorasib as second-line treatment for patients with KRAS-G12C-mutated metastatic non-small cell lung cancer (mNSCLC) in Switzerland by Tämer El Saadany, Judith Lupatsch, Michael Mark, Michaela Barbier, Tarun Mehra, Matthias Schwenkglenks, Roger von Moos

“…The costs of drugs, drug administration, diagnostics, disease management, and adverse events were considered. Because the price of sotorasib has not been established in Switzerland, two scenarios were analysed: the first used the published expected monthly United Kingdom (UK) price in Swiss francs (CHF 7870); the second used one-quarter of that price (CHF 1968), according to the lower dose used in the most recent trial, under the condition that one-quarter of the original sotorasib dose is equally effective. …”
Get full text

100 essential questions for the future of agriculture by Yuming Hu, Taolan Zhao, Yafang Guo, Meng Wang, Kerstin Brachhold, Chengcai Chu, Andrew Hanson, Sachin Kumar, Rongcheng Lin, Wenjin Long, Ming Luo, Jian Feng Ma, Yansong Miao, Shaoping Nie, Yu Sheng, Weiming Shi, James Whelan, Qingyu Wu, Ziping Wu, Wei Xie, Yinong Yang, Chao Zhao, Lei Lei, Yong‐Guan Zhu, Qifa Zhang

Get full text

Clinical practice of one-lung ventilation in mainland China: a nationwide questionnaire survey by Hong-jin Liu, Yong Lin, Wang Li, Hai Yang, Wen-yue Kang, Pei-lei Guo, Xiao-hui Guo, Ning-ning Cheng, Jie-chao Tan, Yi-na He, Si-si Chen, Yan Mu, Xian-wen Liu, Hui Zhang, Mei-fang Chen

“…Implementing volume control ventilation mode and early management of oxygen desaturation might prevent hypoxemia during OLV.…”
Get full text

Evidence to practice – lessons learnt in developing an implementation strategy for an online digital health intervention (Eczema Care Online) by Laura Howells, Kim S. Thomas, Miriam Santer, Ingrid Muller, Kate Greenwell, Amanda Roberts, Hywel C. Williams, Jane Harvey, Stephanie J. Lax, Natasha K. Rogers, Tracey H. Sach, Sandra Lawton, Mary Steele, Katy Sivyer, Julie Hooper, Amina Ahmed, Sylvia Wilczynska, Sinead Langan, Paul Leighton

“…Abstract Background Eczema Care Online ( www.EczemaCareOnline.org.uk/ ) is an online self-management toolkit which includes tailored content for young people (13–25 years) and for parents of children that have eczema (0–12 years). …”
Get full text

Assembly mechanisms, not species pool, shape β-diversity of soil methanotrophic communities in steppes of China by Yongping Kou, Zhe Feng, Huan Li, Yanjiao Liu, Yanjiao Liu, Lin Xu, Lin Xu, Xiangzhen Li

“…Notably, the differential environmental conditions (such as soil pH, yearly average temperature, and precipitation) across scales and steppe habitats primarily modulate the intensity of these assembly processes, thereby influencing β-diversity.ConclusionIn summary, our study emphasizes the crucial role of local community assembly in changing soil methanotrophic β-diversity’s geographical patterns, highlighting the significance of a nuanced understanding of these processes for effective conservation and management strategies.…”
Get full text

Erectile Function and Sexual Activity Are Declining in the Younger Generation: Results from a National Survey in Japan by Akira Tsujimura, Shinichiro Fukuhara, Koji Chiba, Tsuyoshi Yoshizawa, Hikaru Tomoe, Masato Shirai, Kazunori Kimura, Eiji Kikuchi, Eri Maeda, Yoshikazu Sato, Atsushi Nagai, Koichi Nagao, Haruaki Sasaki

Feasibility of trancutaneous auricular vagus nerve stimulation in Black and Hispanic/Latino people with peripheral neuropathy by Marlon L. Wong, Eva Widerström-Noga, Jessica L. Bolanos, Gabriel Gonzalez, Frank J. Penedo, Peter J. Hosein, Melissa M. Tovin, Juan P. Gonzalez, Lisa M. McTeague

“…The survey assessed symptom burden, management strategies, and interest in taVNS among CIPN patients. …”
Get full text

Elevations in D-dimer levels in patients with Plasmodium infections: a systematic review and meta-analysis by Suriyan Sukati, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay, Ching-Ping Tseng, Aongart Mahittikorn, Nsoh Godwin Anabire, Polrat Wilairatana, Kinley Wangdi, Hideyuki J Majima, Apiporn Thinkhamrop Suwannatrai, Wiyada Kwanhian Klangbud, Wanida Mala, Rujikorn Rattanatham, Manas Kotepui

“…Additionally, large, multicentric cohorts are needed to establish robust guidelines for incorporating D-dimer into malaria management practices. Further research should also explore the role of D-dimer in the pathogenesis of Plasmodium infections to deepen our understanding of their clinical significance.…”
Get full text

Sex differences in the associations of water, coffee and tea consumption with cardiovascular diseases: a prospective cohort study by Dandan Ke, Dandan Ke, Yueqing Wang, Yabing Hou, Weihao Shao, Jiawen Ke, Xiaoxuan Zhang, Hongxi Yang, Zhong He, Zuolin Lu

Get full text

Toward Enteral Nutrition in the Treatment of Pediatric Crohn Disease in Canada: A Workshop to Identify Barriers and Enablers by Johan Van Limbergen, Jennifer Haskett, Anne M Griffiths, Jeff Critch, Hien Huynh, Najma Ahmed, Jennifer C deBruyn, Robert Issenman, Wael El-Matary, Thomas D Walters, Cheryl Kluthe, Marie-Eve Roy, Elizabeth Sheppard, Wallace V Crandall, Stan Cohen, Frank M Ruemmele, Arie Levine, Anthony R Otley

“…To chart and address enablers and barriers of use of EEN in Canada, a workshop was held in September 2014 in Toronto (Ontario), inviting pediatric gastroenterologists, nurses and dietitians from most Canadian pediatric IBD centres as well as international faculty from the United States and Europe with particular research and clinical expertise in the dietary management of pediatric CD. Workshop participants ranked the exclusivity of enteral nutrition; the health care resources; and cost implications as the top three barriers to its use. …”
Get full text

Beyond identification of familial hypercholesterolemia: Improving downstream visits and treatments in a large health care system by Harin Lee, Tarun Kadaru, Ruth Schneider, Taylor Triana, Carol Tujardon, Colby Ayers, Mujeeb Basit, Zahid Ahmad, Amit Khera

“…Conclusions: Approximately 1 in 5 individuals in a large healthcare system who were contacted for a recorded LDL-C ≥ 190 mg/dL had a meaningful improvement in the management of severe hypercholesterolemia and diagnosis of FH. …”
Get full text

Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential implica... by Daniel Leduc, Ashley A. Rowden, Ashley A. Rowden, Sarah Seabrook, David A. Bowden, Andrew R. Thurber, Andrew R. Thurber, Jane Halliday, Cliff S. Law, Cliff S. Law, Olivia S. Pereira, Bethany G. Whitten, Andrew Marriner

“…Impact on seep communities from gas hydrate extraction processes may occur via reduction or potentially cessation of free-gas methane supply to the seafloor, ‘sand’ production at the seafloor due to the physical degradation of the substrate structure, or alteration of the structural integrity of the seafloor substrate. Any spatial management options considered for managing these impacts should reflect the differences in benthic community structure between depths and locations on the Hikurangi Margin.…”
Get full text

Security and religion in democratizing Tunisia: re-enacting surveillance through religious narratives and gendered dynamics by Fabrizio Leonardo Cuccu, Alessandra Bonci

“…Finally, we present the case of the wa’ydhat in the post-revolutionary setting as a critical example of securitization of Islam, and cooperation between security and religious management.…”
Get full text

مطالعه اثر ارتفاع، سطح و تراکم پوشش گیاهی ماشک مراغه و ماشک گلشن بر کاهش رواناب و رسوب by ایمان صالح, مجید خزایی, حمیدرضا پیروان, بهروز واعظی

Get full text

Enhancing interprofessional ward rounds by identifying factors associated with low satisfaction and efficiency: a quantitative and qualitative national survey of Swiss healthcare p... by Armon Arpagaus, Aron Strub, Rahel Kuster, Christoph Becker, Sebastian Gross, Flavio Gössi, Eliska Potlukova, Stefano Bassetti, Drahomir Aujesky, Philipp Schuetz, Sabina Hunziker

“… AIMS OF THE STUDY: Interprofessional ward rounds are a cornerstone of patient-centred care for medical inpatients and offer opportunities to discuss and coordinate patient treatment and further management. We aimed to identify factors associated with lower satisfaction and efficiency of interprofessional ward rounds, as reported by physicians and nurses. …”
Get full text

Metabolic resistance to pyrethroids with possible involvement of non-coding ribonucleic acids in Anopheles funestus, the major malaria vector in western Kenya by Isaiah Debrah, Daibin Zhong, Maxwell G. Machani, Godfrey Nattoh, Kevin O. Ochwedo, Collins M. Morang’a, Ming-Chieh Lee, Linda E. Amoah, Andrew K. Githeko, Yaw A. Afrane, Guiyun Yan

“…Targeting non-coding RNAs for intervention development could help in insecticide resistance management.…”
Get full text

Le mouvement étudiant et la question des langues en Algérie (1962-1965) : à propos d’un épisode méconnu de l’histoire de l’UGEMA-UNEA by Yassine Temlali

“…This organisation would adhere to the programme of the FLN, established in 1962 as a single party, and mobilised students in support of the initiatives of the government (joint worker-management control, nationalisation, etc.), notably through voluntary service campaigns. …”
Get full text

Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China by Mary Bachman DeSilva, Allen L. Gifford, Xu Keyi, Zhong Li, Cheng Feng, Mohamad Brooks, Mark Harrold, Hu Yueying, Christopher J. Gill, Xie Wubin, Taryn Vian, Jessica Haberer, David Bangsberg, Lora Sabin

Get full text

Dietary supplementation of organic selenium to improve growth performance and protein utilization in African catfish fed with different protein level diets by Giri Maruto Darmawangsa, Muhammad Agus Suprayudi, Nurbambang Priyo Utomo, Julie Ekasari

Get full text