Tirzepatide in Sport: A Comprehensive Review of its Metabolic Impacts and Potential Applications for Athletes by Wiktor Biesiada, Ewelina Kopczyńska, Piotr Kulej, Justyna Woźniak, Justyna Weronika Kmieć, Anna-Mariia Chernysh, Aleksandra Dusińska, Jakub Waszczyński, Kamila Fuczyło, Karolina Stankevič

“… Introduction Tirzepatide, a dual agonist of glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, has emerged as a transformative metabolic therapy with exceptional efficacy in weight management and glycemic control. Its relevance in sports science is growing, with potential benefits in weight optimization, energy balance, and recovery. …”
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Comparison of specialist ataxia centres with non-specialist services in terms of care access and organisation, health services resource utilisation and costs in Germany using patie... by Julie Vallortigara, Julie Greenfield, Barry Hunt, Holm Graessner, Carola Reinhard, Andreas Nadke, Bart-Jan Schuman, Deborah Hoffman, Steve Morris, Paola Giunti

“…Background: The ataxias are rare complex neurological disorders challenging to diagnose and manage. We explored the patient pathways, health care use and costs of individuals attending a specialist ataxia centre (SAC) compared with non–specialist settings in Germany. …”
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Private, public, and bottled drinking water: Shared contaminant-mixture exposures and effects challenge by Paul M. Bradley, Kristin M. Romanok, Kelly L. Smalling, Stephanie E. Gordon, Bradley J. Huffman, Katie Paul Friedman, Daniel L. Villeneuve, Brett R. Blackwell, Suzanne C. Fitzpatrick, Michael J. Focazio, Elizabeth Medlock-Kakaley, Shannon M. Meppelink, Ana Navas–Acien, Anne E. Nigra, Molly L. Schreiner

“…In the United States, point-of-use DW (POU–DW) is supplied via private tapwater (TW), public-supply TW, and bottled water (BW). Differences in management, monitoring, and messaging and lack of directly–intercomparable exposure data influence the actual and perceived quality and safety of different DW supplies and directly impact consumer decision–making. …”
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NOX4 modulates breast cancer progression through cancer cell metabolic reprogramming and CD8+ T cell antitumor activity by Yingying Xiong, Yiming Weng, Shan Zhu, Jian Qin, Jia Feng, Xiaopeng Jing, Chao Luo, Wei Gong, Rui Sun, Min Peng

“…Therapeutically targeting the NOX4–MYC axis and leveraging NOX4’s immunomodulatory capacity could offer promising strategies for breast cancer management.…”
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The state of combined thoracoabdominal triple-organ transplantation in the United States by Emily G. Dunbar, BS, Ye In Christopher Kwon, BA, Matthew Ambrosio, MS, Inna F. Tchoukina, MD, Keyur B. Shah, MD, David A. Bruno, MD, Walker A. Julliard, MD, Josue Chery, MD, Vigneshwar Kasirajan, MD, Zubair A. Hashmi, MD

“…A careful, multidisciplinary approach to patient selection and management remains paramount in optimizing outcomes for high-risk patients undergoing TOTs.…”
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Medicarpin induces G1 arrest and mitochondria-mediated intrinsic apoptotic pathway in bladder cancer cells by Chen Yuan, Yin Liqi, Hao Mingxuan, Xu Wenkai, Gao Jixian, Sun Yuxin, Wang Qiao, Chen Shi, Liang Youfeng, Guo Rui, Zhang Jinku, Li Jinmei, Zhai Qiongli, Cheng Runfen, Wang Jiansong, Wang Haifeng, Yang Zhao

“…Hence, a novel therapeutic strategy in the clinical management of BC is urgently needed. Medicarpin (MED), an isoflavone from Dalbergia odorifera, can promote bone mass gain and kill tumor cells, but its anti-BC effect remains obscure. …”
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Association between the composite dietary antioxidant index and non-alcoholic fatty liver disease: evidence from National Health and Nutrition Examination Survey 2005–2016 by Yidian Fu, Yidian Fu, Chao Jiang, Zonglin Li, Xiangyun Shi, Peiyuan Lv, Peiyuan Lv, Jingbo Zhang

“…This association highlights the potential for dietary interventions to reduce NAFLD incidence and underscores the need for future research, including clinical trials and mechanistic studies, to further explore the role of dietary antioxidants in NAFLD prevention and management.…”
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Comparison of TAP block and epidural analgesia for postoperative analgesia after robotic-assisted radical prostatectomy by O.O. Volkov, Lutsenko V.V., M.O. Plis, M.V. Pavlenko, Krishtafor D.A.

“…Both epidural analgesia and TAP block have shown sufficient safety profile and efficacy in postoperative pain management. After radical prostatectomy, the TAP-block is an effective method of analgesia, while not interfering with the timely full mobilization of the patient. …”
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Experimental study on the strengthening mechanism of carbon fiber-reinforced sand powder 3D-printed rock-like materials by Lishuai Jiang, Xin He, Ye Zhao, Pimao Li, Yang Zhao, Zongke Wang, Dingrui Guo, Qi Gu

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Association between clinical-biological characteristics of Klebsiella pneumoniae and 28-day mortality in patients with bloodstream infection by Xiaofeng Yu, Yi Zhao, Xiao Sun, Jiahui Luan, Haiyan Wang, Tianyu Sun, Tongtong Lin, Xia Zhou, Wei Yang, Ziguang Deng, Bo Liu, Hongyun Cao

“…It may facilitate the clinical management of patients with bloodstream infection (BSI) caused by hypervirulent KP strains, especially those with rfbA/B/D genes. …”
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Predictive role of modifiable factors in stroke: an umbrella review by Yue Wang, Lu Wen, Xiaotong Wang, Man Liang, Fanxin Zeng, Yuetian Yang, Fangfang Nie, Mengke Shang, Na Ta, Lanxin Ou, Zhibin Yang, Wanyang Liu

“…No publication bias existed, except only one study which could be explained by reporting bias.Discussion Diet with rich macronutrients and micronutrients, healthy dietary patterns and favourable physical, emotional health and environmental management should be promoted to decrease the burden of stroke.PROSPERO registration number CRD42021249921.…”
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Development of delayed pulmonary toxicities and transcriptional changes in pre-existing interstitial lung disease mice after partial thoracic irradiation by Jiamei Fu, Xinglong Liu, Yuchuan Zhou, Shengnan Zhao, Liang Zeng, Yan Pan, Jianghong Zhang, Kevin M. Prise, Chunlin Shao, Yaping Xu

“…No approved biomarker or medicine is available to prevent pulmonary toxicities in LC-ILD patients. Appropriate management for them remains a challenge for clinicians due to treatment-related complications. …”
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Cerebrospinal fluid dynamics and subarachnoid space occlusion following traumatic spinal cord injury in the pig: an investigation using magnetic resonance imaging by Madeleine Amy Bessen, Christine Diana Gayen, Ryan L. O’Hare Doig, Ryan Michael Dorrian, Ryan David Quarrington, Adnan Mulaibrahimovic, Vartan Kurtcuoglu, Angela Catherine Walls, Anna Victoria Leonard, Claire Frances Jones

“…SAS occlusion can change pulsatile cerebrospinal fluid (CSF) dynamics, which could have acute clinical management implications. This study aimed to characterise SAS occlusion and investigate CSF dynamics over 14 days post-SCI in the pig. …”
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Warming-driven migration of enterotypes mediates host health and disease statuses in ectotherm Litopenaeus vannamei by Shenzheng Zeng, Zhijian Huang, Satapornvanit Kriengkrai, Renjun Zhou, Derun Yuan, Nguyễn Văn Tuấn, Zhiming Zhu, Luwei Zheng, Qilu Hou, Xuanting Li, Qi Chen, Lingyu Zhang, Dongwei Hou, Zhixuan Deng, Shicheng Bao, Wenjun Wang, Sukontorn Khoruamkid, Soo Loon Goh, Shaoping Weng, Jianguo He

“…These findings enlarged the cognition of shrimp health culture management from a microecological perspective, and alerted the inevitable challenge of global warming to ectothermic animals.…”
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HUBUNGAN KADAR KOLESTEROL DENGAN TEKANAN DARAH PENDERITA HIPERTENSI DI DUSUN SIDOMULYO DESA REJOAGUNG KECAMATAN PLOSO KABUPATEN JOMBANG The Correlation of Cholesterol levels with... by HENI MARYATI

“…Provide information to patients in order to monitor the levels of total cholesterol are advised to remain in the normal range (<200 mg / dl) as well as lifestyle management. Key terms : cholesterol levels. Blood Pressure, Hypertension Patients …”
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Catheter ablation versus antiarrhythmic drugs with risk factor modification for treatment of atrial fibrillation: a protocol of a randomised controlled trial (PRAGUE-25 trial) by Stepan Havranek, Jiri Jarkovsky, Otakar Jiravský, Pavel Osmancik, Veronika Bulková, Jan Chovančík, Tomáš Roubíček, Dalibor Heřman, Zuzana Čarná, Vladimír Tuka, Martin Matoulek, Martin Fiala, Sylvie Stregl-Hruskova, Adam Latiňák, Jiřina Kotryová

“…The aim of the trial is to compare the efficacy of modern invasive (CA) and non-invasive (AADs with risk factor management) treatment of AF.Methods and analysis The trial will be a prospective, multicentre, randomised non-inferiority trial. …”
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Effect of Meridian Massage combined with Swallowing Rehabilitation Training on Elderly Patients with Dysphagia after Stroke by Hui FAN, Zhongqin XU, Chunxia MA, Lei DONG, Yao ZHOU

“…The control group was given routine swallowing rehabilitation training on the basis of routine treatment and early rehabilitation exercise, mainly including swallowing organ training, ice stimulation, cough and breathing training and feeding management, once a day, six days a week, continous training for four weeks, followed up for 12 weeks after discharge. …”
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Testing a multi-behavioral intervention to improve oral health behaviors in the pediatric dental surgery population: protocol for the PROTECT trial by Joanna Buscemi, Teresa G. Borowski, David Avenetti, Lisa Tussing-Humphreys, Lisa Tussing-Humphreys, Lisa Tussing-Humphreys, Molly Martin, Molly Martin, Marc S. Atkins, Teresa Marshall, Michael Berbaum, Helen H. Lee, Helen H. Lee

“…., goal setting, problem solving, self-monitoring), positive parenting and stress management and maintenance. Our two primary outcomes are parental assisted toothbrushing (twice/day, 2 min each time) and reduced added sugar consumption (less than 10% of overall daily caloric intake). …”
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Optimization of stocking density in intensification of mud crab Scylla serrata cultivation in the resirculation system by Yuni Puji Hastuti, Kukuh Nirmala, Iman Rusmana, Ridwan Affandi, Wahyu Budi Kuntari

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UTE MRI technical developments and applications in osteoporosis: a review by Soo Hyun Shin, Hee Dong Chae, Hee Dong Chae, Arya Suprana, Arya Suprana, Saeed Jerban, Eric Y. Chang, Eric Y. Chang, Lingyan Shi, Robert L. Sah, Jeremy H. Pettus, Gina N. Woods, Jiang Du, Jiang Du, Jiang Du

“…These UTE-MRI advancements hold great potential for improving the diagnosis and management of osteoporosis and other metabolic bone diseases by providing a more comprehensive assessment of bone quantity and quality.…”
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