Safety of interleukin inhibitors in patients with plaque psoriasis and history of neoplasms: a multicenter retrospective study – IL PSO (Italian landscape psoriasis) by Mario Valenti, Luciano Ibba, Sara Di Giulio, Luigi Gargiulo, Piergiorgio Malagoli, Anna Balato, Carlo G. Carrera, Paolo Dapavo, Eugenia V. Di Brizzi, Valentina Dini, Francesca Gaiani, Francesco Loconsole, Angelo V. Marzano, Matteo Megna, Alessandra Michelucci, Luca Potestio, Simone Ribero, Antonio Costanzo, Alessandra Narcisi

“…Background: Interleukin (IL) inhibitors are increasingly used in the management of moderate-to-severe plaque psoriasis. However, their use in patients with a history of cancer is debated.Objective: We conducted a multicenter retrospective study across nine Italian Dermatology Units to assess the real-world effectiveness and safety of IL inhibitors (IL-23, IL-17, IL-12/23) in 136 oncological patients with moderate-to-severe plaque psoriasis. …”
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Lake pulses driven by glacier melting and climate variability by Songtao Ai, Shoukat Ali Shah, Yi Cai, Jiajun Ling, Xinde Chu, Shijin Wang, Yuande Yang, Runchuan Ouyang, Jiachun An, Wolfgang Rack

“…This study has the potential to reveal broader implications for water resource management, ecosystem dynamics, and climate change adaptation in regions dependent on glacier-fed lakes.…”
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Implementing Bayesian inference on a stochastic CO2-based grey-box model by Shujie Yan, Jiwei Zou, Chang Shu, Justin Berquist, Vincent Brochu, Marc Veillette, Danlin Hou, Caroline Duchaine, Liang (Grace) Zhou, Zhiqiang (John) Zhai, Liangzhu (Leon) Wang

“…The approach proposed by this study improves the interpretation of CO2 monitoring data, thereby facilitating the future real-time IAQ management.…”
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Effects of urbanization on the ephemeral lake flood risks under subtropical humid monsoon climate by Biqing Tian, Chaojun Gu, Hao Jia, Peng Gao, Liping Guo, Xingmin Mu

“…Implementing proactive ecological management measures around lakes and riverbanks has mitigated flood risks across 22 administrative regions, reducing high-risk flood areas by 92.15 km². …”
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Decision-making under epistemic, strategic and institutional uncertainty during COVID-19: findings from a six-country empirical study by Clare Wenham, Alexandra L Phelan, Winifred Ukponu, Sumegha Asthana, Tahmina Shirin, Claire J Standley, Adachioma Chinonso Ihueze, Sanjana Mukherjee, Ibrahim B Gobir, Mohannad Al Nsour, JJ Woo, Mohammad Mushtuq Husain, Nevashan Govender, Roujia Lin, Sumit Asthana, Renee Vongai Mutare

“…The COVID-19 pandemic management was significantly impacted by uncertainty, as the gaps between existing information and the necessary knowledge hindered decision-making. …”
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Response of Natural Forests and Grasslands in Xinjiang to Climate Change Based on Sun-Induced Chlorophyll Fluorescence by Jinrun He, Jinglong Fan, Zhentao Lv, Shengyu Li

“…This study provides an important scientific basis for ecological management and climate adaptation in Xinjiang, emphasizing the need for differentiated strategies across ecological regions to support sustainable development.…”
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Interrelation between hypoxic liver injury and Killip classification in ST-segment elevation myocardial infarction patients by Seong Huan Choi, Ji-Hun Jang, Dae-Young Kim, Young Ju Suh, Yong-Soo Baek, Sung-Hee Shin, Seong-Ill Woo, Dae-Hyeok Kim, Jeonggeun Moon, Jon Suh, WoongChol Kang, Sang-Don Park, Sung Woo Kwon

“…Early recognition of HLI and accurate assessment of Killip classification is warranted for effective management of STEMI.…”
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The availability of drugs for stable COPD treatment in China: a cross-sectional survey by Dongru Du, Xueru Hu, Qiunan Zuo, Dan Xu, Tao Zhu, Tao Fan, Jiao Yang, Weiguo Xu, Hailong Wei, Kangzhuo Baima, Ying Zhang, Yanhui Gu, Lei Chen, Fengming Luo, Yongchun Shen, Fuqiang Wen

“…A well-constructed questionnaire was designed according to the Chinese Guidelines for the Diagnosis and Management of COPD (revised version 2021). Both inhaled drugs (monotherapy, double therapy and triple therapy) and oral drugs (expectorants, theophylline, antibiotics, and bacterial lysates) were included in this survey. …”
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An explainable Bi-LSTM model for winter wheat yield prediction by Abhasha Joshi, Biswajeet Pradhan, Subrata Chakraborty, Subrata Chakraborty, Renuganth Varatharajoo, Abdullah Alamri, Shilpa Gite, Chang-Wook Lee

“…Accurate, reliable and transparent crop yield prediction is crucial for informed decision-making by governments, farmers, and businesses regarding food security as well as agricultural business and management. Deep learning (DL) methods, particularly Long Short-Term Memory networks, have emerged as one of the most widely used architectures in yield prediction studies, providing promising results. …”
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Water conservation assessment and its influencing factors identification using the InVEST and random forest model in the northern piedmont of the Qinling Mountains by Song He, Hui Qian, Yuan Liu, Xiaoguang Zhao, Fengmei Su, Huan Ma, Zilong Guan, Tao Zhang

“…The results and conclusions of this study could provide scientific insights for water security and ecosystem management in the NPQM region.…”
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E-cigarettes on Instagram: Exploring vape content via an Australian vaping influencer by Jonine Jancey, Renee N. Carey, Becky Freeman, Tama Leaver, Katharina Wolf, Marilyn Bromberg, Kevin Chai, Stella Bialous, Phoebe Adams, Meghan Mcleod, Kahlia McCausland

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Metrics for Evaluating Telemedicine in Randomized Controlled Trials: Scoping Review by Yuka Sugawara, Yosuke Hirakawa, Masao Iwagami, Ryota Inokuchi, Rie Wakimizu, Masaomi Nangaku

“…Not only does telemedicine contribute to improved patient quality of life and satisfaction by reducing travel time and allowing patients to be seen in their usual environment, but it also has the potential to improve disease management by making it easier for patients to see a doctor. …”
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Neuropsychiatric adverse events associated with Glucagon-like peptide-1 receptor agonists: a pharmacovigilance analysis of the FDA Adverse Event Reporting System database by Wenchao Lu, Shihan Wang, Huilin Tang, Tao Yuan, Wei Zuo, Yuling Liu

“…Abstract Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used due to their profound efficacy in glycemic control and weight management. Real-world observations have revealed potential neuropsychiatric adverse events (AEs) associated with GLP-1RAs. …”
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Genetic profiling of multidrug-resistant Acinetobacter baumannii from a tertiary care center in Malaysia by Aisyah Syakirah Shahari, Navindra Kumari Palanisamy, Fadzilah Mohd Nor

“…The antibiotic susceptibility data with its resistance mechanisms would contribute to and facilitate the management and infection control caused by MDRAB.…”
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Humanizing processes after harm part 1: patient safety incident investigations, litigation and the experiences of those affected by Lauren Ramsey, Laura Sheard, Justin Waring, Siobhan McHugh, Ruth Simms-Ellis, Ruth Simms-Ellis, Gemma Louch, Katherine Ludwin, Jane K. O’Hara

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Therapeutic Efficacy of Intranasal <i>N</i>-Acetyl-L-Cysteine with Cell-Penetrating Peptide-Modified Polymer Micelles on Neuropathic Pain in Partial Sciatic Nerve Ligation Mice by Hiroshi Nango, Ai Takahashi, Naoto Suzuki, Takumi Kurano, Saia Sakamoto, Taiki Nagatomo, Toyofumi Suzuki, Takanori Kanazawa, Yasuhiro Kosuge, Hiroko Miyagishi

“…<b>Conclusions</b>: These results suggest that the post-onset intranasal administration of NAC/PPT ameliorates mechanical allodynia by suppressing microglia induction and that intranasal delivery with PEG-PCL-Tat might be a useful tool for the pharmacological management of neuropathic pain.…”
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Evaluation of spinal deformity and its progression in pyogenic spondylodiscitis: A retrospective MRI study of 59 cases by Andreas Kramer, Jonathan Neuhoff, Santhosh G. Thavarajasingam, Rebecca Sutherland, Hugh McCaughan, Benjamin Davies, Ehab Shiban, Florian Ringel, Andreas K. Demetriades

“…Introduction: Pyogenic spondylodiscitis management often remains conservative without surgical intervention, yet the risk of spinal deformity under such therapy is unclear. …”
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Transforming Non-Digital, Clinical Workflows to Detect and Track Vision-Threatening Diabetic Retinopathy via a Digital Platform Integrating Artificial Intelligence: Implementation... by Peranut Chotcomwongse, Paisan Ruamviboonsuk, Chaiwat Karavapitayakul, Koblarp Thongthong, Anyarak Amornpetchsathaporn, Methaphon Chainakul, Malee Triprachanath, Eckachai Lerdpanyawattananukul, Niracha Arjkongharn, Varis Ruamviboonsuk, Nattaporn Vongsa, Pawin Pakaymaskul, Turean Waiwaree, Hathaiphan Ruampunpong, Richa Tiwari, Viroj Tangcharoensathien

“…Abstract Introduction Screening diabetic retinopathy (DR) for timely management can reduce global blindness. Many existing DR screening programs worldwide are non-digital, standalone, and deployed with grading retinal photographs by trained personnel. …”
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Risk Index Model of Property and Cargo Insurance Claims Based on Precipitation in Hunan by Peng Weiying, Li Yueyong, Tan Shiqi, Li Hao, Guan Jianwen, Liao Chunhua, Zhou Wei, Xie Ruiheng

“…In conclusion, the study emphasizes the significance of integrating meteorological insights with insurance analytics to enhance risk management strategies. By leveraging advanced modeling techniques and data-driven approaches, Hunan Province is better equipped to anticipate, assess and mitigate the impact of precipitation-related risks on property and cargo insurance, ultimately bolstering resilience and preparedness in the face of natural disasters.…”
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Establishment of a prognostic signature and immune infiltration characteristics for uterine corpus endometrial carcinoma based on a disulfidptosis/ferroptosis-associated signature by Yong Huang, Huibin Li, Zhifu Wei, Wanshan He, Bin Chen, Shuang Cheng, Zhifang Zhao, Lv Deng, Lv Deng, Xiaohua Chen, Yu Lin, Yu Lin, Xiaoshan Hong, Xiaoshan Hong

“…The comprehensive assessment of disulfidptosis and ferroptosis provides new insights to further guide patient clinical management and personalized treatment.…”
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