Deoxycholic Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Exacerbates DSS-Induced Colitis through Promoting Cathepsin B Release by Shengnan Zhao, Zizhen Gong, Xixi Du, Chunyan Tian, Lingyu Wang, Jiefei Zhou, Congfeng Xu, Yingwei Chen, Wei Cai, Jin Wu

“…Therefore, our findings suggest that S1PR2/ERK1/2/cathepsin B signaling plays a critical role in triggering inflammasome activation by DCA and S1PR2 may represent a new potential therapeutic target for the management of intestinal inflammation in individuals on a high-fat diet.…”
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Diagnostic performance of the DISQVER metagenomic sequencing tool for the identification of pathogens in febrile neutropenic patients: the ADNEMIA trial by Geneviève Héry-Arnaud, Christophe Burucoa, Marie Kempf, David Boutoille, Yohann Foucher, Philippe Lanotte, Maxime Pichon, Stéphane Corvec, Cécile Le Brun, Helene Pailhories

“…Secondary outcomes will evaluate patient management depending on the arm. The second secondary outcome will be determined by the duration of conventional assessment, frequency of microorganisms detected during routine care and percentage distribution of theoretical adjustments made to anti-infective treatment based on microorganisms diagnosed using the mNGS-DISQVER tool as compared with conventional practices. …”
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Soluble Markers of Antibody Secreting Cell Function as Predictors of Infection Risk in Rheumatoid Arthritis by Maria J. Gutierrez, Stephen V. Desiderio, Nae-Yuh Wang, Erika Darrah, Laura Cappelli, Gustavo Nino, Michelle Jones, Clifton O. Bingham

“…Further delineating the link between ASC and infection susceptibility in RA may optimize disease management and provide novel insights into disease pathogenesis that are susceptible to intervention.…”
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Combined impacts of climate change and human activities on blue and green water resources in a high-intensity development watershed by X. Tan, B. Liu, X. Tan, X. Tan, Z. Huang, J. Fu

“…<p>Sustainable management of blue and green water resources is vital for the stability and sustainability of watershed ecosystems. …”
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Quality of Life as Medicine III. A Qualitative Analysis of the Effect of a Five-Day Intervention with Existential Holistic Group Therapy or a Quality of Life Course as a Modern Rit... by Søren Ventegodt, Birgitte Clausen, Maja Langhorn, Maximilian Kromann, Niels Jørgen Andersen, Joav Merrick

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A maChine and deep Learning Approach to predict pulmoNary hyperteNsIon in newbornS with congenital diaphragmatic Hernia (CLANNISH): Protocol for a retrospective study. by Ilaria Amodeo, Giorgio De Nunzio, Genny Raffaeli, Irene Borzani, Alice Griggio, Luana Conte, Francesco Macchini, Valentina Condò, Nicola Persico, Isabella Fabietti, Stefano Ghirardello, Maria Pierro, Benedetta Tafuri, Giuseppe Como, Donato Cascio, Mariarosa Colnaghi, Fabio Mosca, Giacomo Cavallaro

“…The development of predictive models in CDH outcomes will provide a key contribution in disease prediction, early targeted interventions, and personalized management, with an overall improvement in care quality, resource allocation, healthcare, and family savings. …”
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Attention-Driven Hybrid Ensemble Approach With Bayesian Optimization for Accurate Energy Forecasting in Jeju Island&#x2019;s Renewable Energy System by Muhammad Ali Iqbal, Joon-Min Gil, Soo Kyun Kim

“…The rapid integration of renewable energy sources into power grids has created an urgent need for accurate energy demand and supply forecasting models capable of managing the inherent variability of renewable energy generation. …”
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Peripheral corneal ulcers in association with rheumatic diseases by E.A. Drozdova

“…Tear production, as measured by Schirmer's test, was 6±2 mm, while tear film stability was 2±1 mm. Conservative management was found to be effective in 59.4% (outpatient treatment in 40.6% and inpatient treatment in 18.7%). …”
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Big Data Governance Challenges Arising From Data Generated by Intelligent Systems Technologies: A Systematic Literature Review by Yunusa Adamu Bena, Roliana Ibrahim, Jamilah Mahmood, Arafat Al-Dhaqm, Ahmad Alshammari, Maged Nasser, Muhammed Nura Yusuf, Matthew O. Ayemowa

“…Organizations adopting these technologies face challenges in managing the volume, variety, and velocity of data while ensuring quality, security, compliance, and ethical integrity. …”
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Effects of Nitrogen Fertilization on Soil CH₄, CO₂, and N₂O Emissions and Their Global Warming Potential in Agricultural Peatlands by Yao Shi, Xiaowei Wei, Lianxi Sheng, Xuechen Yang

“…This study helps to provide theoretical support for the development of effective peatland management strategies.…”
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Hydroxyurea mitigates diabetic kidney disease through mTOR-S6K signaling pathway in STZ-induced diabetic mice by Wanying Cheng, Cenzhu Wang, Meican Ma, Yu Zhou

“…Such a combination approach could simultaneously address hyperglycemia and renal dysfunction, offering a more comprehensive management strategy for DKD.…”
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‘Communication, that is the key’: a qualitative investigation of how essential workers with COVID-19 responded to public health information by Yanbing Chen, Claire Buckley, Elizabeth Alvarez, Conor Buggy, Mark Roe, Mary Codd, Anne Drummond, Carolyn Ingram, Penpatra Sripaiboonkij, Carla Perrotta, Mary Archibald, Vicky Downey, Natalia Rachwal

“…Objectives To understand how essential workers with confirmed infections responded to information on COVID-19.Design Qualitative analysis of semistructured interviews conducted in collaboration with the national contact tracing management programme in Ireland.Setting Semistructured interviews conducted via telephone and Zoom Meetings.Participants 18 people in Ireland with laboratory confirmed SARS-CoV-2 infections using real-time PCR testing of oropharyngeal and nasopharyngeal swabs. …”
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Vertical flow immunoassay for multiplex mycotoxins based on photonic nitrocellulose and SERS nanotags by Ruipeng Chen, Jingfang Hu, Hui Wang, Cheng Li, Haiqi Kang, Yuxuan Chen, Liang Yang, Xiangfang Tang, Benhai Xiong, Xiangwei Zhao

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PreciPalm: An Intelligent System for Calculating Macronutrient Status and Fertilizer Recommendations for Oil Palm on Mineral Soils Based on a Precision Agriculture Approach by Kudang Boro Seminar, Harry Imantho, null Sudradjat, Sudirman Yahya, Sirojul Munir, Indra Kaliana, Fajar Mei Haryadi, Awalia Noor Baroroh, null Supriyanto, Gani Cahyo Handoyo, Arif Kurnia Wijayanto, Cecep Ijang Wahyudin, null Liyantono, Rhavif Budiman, Achmad Bakir Pasaman, Dwi Rusiawan, null Sulastri

“…The novelty of PreciPalm is that it provides an ecosystem to transparently measure and observe the macronutrient status of oil palm in a timely, visual, spatial, and location-specific manner, thereby improving oil palm nutritional management with more certainty and precision.…”
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Occurrence and assessment of chronic pain fatigue and sleep disturbance in axial spondyloarthritis patients by Eman Abdel Ghani Sayed, Samer Samy, Faruk Ali Abdi, Anna Abou-Raya

“…Additionally, more support and appropriate management of axSpA would be necessary to prevent sleep disorders and their associated complications.…”
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The psychological experience of female caregivers of stroke patients in the rehabilitation period: A qualitative research (脑卒中康复期患者的女性照顾者心理体验的质性研究)... by ZHANG Yingjie (张颖杰), LIU Xingling (刘兴玲), ZENG Wen (曾文), WANG Yilian (汪伊恋), LIU Qun (刘群), LI Yueer (黎月娥)

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Internal Control Systems and Performance of Small and Medium Enterprises in Uganda: A Case Study of Katuna Town Council. by Mubangizi, Martin

“…The target employees included the ones from the following departments, whole sellers, financial managers, money changers, and accountants. A population of 387 employees for the hundred SMEs in Katuna Town Council. …”
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Safety of Drinking Water from Primary Water Sources and Implications for the General Public in Uganda by Keneth Iceland, Kasozi, Sarah, Namubiru, Roland, Kamugisha, Ejike, Daniel Eze, Fred, Ssempijja, Alfred, Omachonu Okpanachi, Hellen, Wambui Kinyi, Jovile Kasande, Atusiimirwe, Dickson Stuart, Tayebwa, Joy, Suubo, Edgar Mario, Fernandez, Nathan, Nshakira, Andrew, Tamale

“…Without such vital information, sustainable development goal number 6 which promotes availability and sustainable management of water and sanitation remains elusive especially in developing countries. …”
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The Impact of Teacher Training on The Academic Performance of Student's Among Secondary Schools in Mbarara District: A Case Study of Kashari County Uganda. by Amumpaire, Catherine

“…This study would be very important to educational institutions all over the country, county, governments, the Ministry of Education (MoE), educational policymakers, school boards of management, and school head teachers and also form a baseline for further research…”
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The Impact of Teacher Training on The Academic Performance of Student's Among Secondary Schools in Mbarara District: A Case Study of Kashari County Uganda. by Amumpaire, Catherine

“…This study would be very important to educational institutions all over the country, county, governments, the ministry of Education (MoE), educational policymakers, school boards of management, and school head teachers and also form a baseline for further research…”
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