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Improving Individualized Salbutamol Treatment: A Population Pharmacokinetic Model for Oral Salbutamol in Virtual Patients
Published 2024-12-01“…Each formulation exhibits distinct pharmacokinetic (PK) and pharmacodynamic (PD) profiles, influencing therapeutic outcomes and adverse effects. Although asthma management predominantly relies on inhaled salbutamol, understanding how these formulations interact with patient-specific characteristics could improve personalized medicine approaches, potentially uncovering the therapeutic benefits of alternative formulations for an individual patient. …”
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41124
Cannabis in cosmetics: regulatory and scientific insights into hemp seed extracts for skincare
Published 2024-12-01“…Both imported and domestically produced hemp oils were evaluated, emphasizing the importance of analytical technology and management at the good agricultural practices and good manufacturing practices levels in cosmetic applications. …”
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41125
Effectiveness and Safety of Dupilumab and Tralokinumab for Treating Atopic Dermatitis and Pruritic Skin Disorders in Oncological Patients: A Narrative Review
Published 2025-01-01“…Real-world data is emerging, facilitated by collaboration between dermatologists and oncologists, supporting the effectiveness and safety of dupilumab and tralokinumab for managing AD in cancer patients. Nonetheless, larger studies with longer follow-up periods and dedicated pharmacovigilance programs are needed to substantiate these findings.Keywords: atopic dermatitis, dupilumab, tralokinumab, oncological patients…”
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41126
Defining the high-risk category of patients with cutaneous melanoma: a practical tool based on prognostic modeling
Published 2025-02-01“…The sensitivity and specificity of the model were 86.1% and 72.7%, respectively.ConclusionThe developed model, which relies on routine histological features, allows the identification of individuals at high risk of CM recurrence to tailor their further management.…”
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41127
Iranian Pediatric COVID-19 Epidemiology and Clinical Characteristics
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41128
Types of Complications and Associated Factors in Patients Undergoing Permanent Cardiac Pacemaker Implantation: A Systematic Review
Published 2025-01-01“…Healthcare providers should emphasize patients with risk factors to provide targeted monitoring and management. Integrating a multidisciplinary approach involving cardiologists, nephrologists, surgeons, and the nursing team is essential to optimizing patient care and improving clinical outcomes.Keywords: complication, heart failure, permanent pacemaker, predictors…”
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Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency
Published 2018-08-01“…Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages…”
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41131
Modern trends and conceptual approaches to understanding the essence of the concept of “national security”
Published 2022-12-01“…Therefore, the reform of national security appears in the unity of three components: normative and legal (regulatory), management (subject) and object (change in the sphere of social relations in the field of national security).…”
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41132
Evaluation of Hematocrit in Adults with Dengue by a Laboratory Information System
Published 2021-01-01“…Hematocrit (Hct), which is often derived from hemoglobin (Hgb), is important in the diagnosis and management of dengue. This study aimed to evaluate the Hct value obtained from the LIS automated analyzer. …”
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Impact of psychostimulants on microbiota and short-chain fatty acids alterations in children with attention-deficit/hyperactivity disorder
Published 2025-01-01“…Evidence suggests that psychostimulant medications, widely used to manage ADHD symptoms, may also impact gut microbiota composition and SCFA levels. …”
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On-Farm Experimentation with Improved Maize Seed and Soil Amendments in Southern Ghana: Productivity Effects in Small Holder Farms
Published 2023-01-01“…Maize production in Ghana is limited by several factors including inadequate use of improved varieties and poor soil fertility management. To contribute to addressing these challenges in maize production, two on-farm experiments were conducted each in the semi deciduous forest and coastal savannah agroecological zones (AEZs) of Ghana during the major and minor cropping seasons of 2017. …”
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Severe Diabetic Ketoacidosis in Children with Type 1 Diabetes: Ongoing Challenges in Care
Published 2025-01-01“…Several prevention strategies, including awareness campaigns, early diagnosis of diabetes, regular monitoring and management, effective insulin therapy, education, access to healthcare and technological assistance, may contribute to reduce the risk of severe diabetic ketoacidosis episodes in children and adolescents.…”
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Prevalence of Chronic Complications, Their Risk Factors, and the Cardiovascular Risk Factors among Patients with Type 2 Diabetes Attending the Diabetic Clinic at a Tertiary Care Ho...
Published 2018-01-01“…Assessment of disease burden is important in taking necessary precautions and management decisions. We aimed to determine the prevalence of macro- and microvascular complications, their risk factors, and coronary artery disease (CAD) risk factors among patients with type 2 diabetes mellitus (T2DM). …”
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The Dose Makes the Poison: Sugar and Obesity in the United States – a Review
Published 2019-08-01“…Low-fat diets have been suggested as the key to weight management. However, over the past 30 years, the calories from fat in people’s diets have gone down, but obesity rates keep climbing. …”
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Application of Real-Coded Genetic Algorithm–PID Cascade Speed Controller to Marine Gas Turbine Engine Based on Sensitivity Function Analysis
Published 2025-01-01“…This research underscores the importance of tailored controller design for effective gas turbine engine management in marine applications.…”
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41140
A QoE and Availability-Aware Framework for Network Slice Placement and Resource Allocation
Published 2025-01-01“…However, this introduces challenges in network management, particularly in efficiently allocating resources to ensure that each network slice meets its specific Quality of Service (QoS) and availability requirements. …”
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