British Policy and Strategy in the Middle East in 1941: Three Wars ‘East of Suez’ by A. M. Fomin

“…After the defeat of France in the summer of 1940, Great Britain was left face to face with the Nazi Germany. It managed to endure the first act of the ‘Battle of Britain’, but could not wage a full-scale war on the continent. …”
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HISS: Snakemake-based workflows for performing SMRT-RenSeq assembly, AgRenSeq and dRenSeq for the discovery of novel plant disease resistance genes by Thomas M. Adams, Moray Smith, Yuhan Wang, Lynn H. Brown, Micha M. Bayer, Ingo Hein

“…These workflows are implemented via Snakemake, a python-based workflow manager. Software dependencies are either shipped with the release or handled with conda. …”
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Participant experiences in HIV cure-directed trial with an extended analytical treatment interruption in Philadelphia, United States by Andrea Bilger, Eion Plenn, Frances K. Barg, Katharine A. Rendle, William B. Carter, Andrea Lamour-Harrington, Nora Jones, Beth Peterson, John A. Sauceda, Pablo Tebas, Karam Mounzer, David Metzger, Luis J. Montaner, Karine Dubé

“…Based on these results, we provide considerations for the conduct of future HIV cure-directed clinical trials involving ATIs. Conclusions Managing expectations, focusing on participants’ contributions, and providing support to reduce feelings of having failed the research team and/or the HIV community following viral rebound should be part of HIV cure trial design. …”
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Systematic review of educational interventions to improve the menstrual health of young adolescent girls by Frances Griffiths, Bronwyn Harris, Chinwe Onuegbu, Rebecca Lane Evans

“…The meta-analysis indicates that larger effect sizes were attained by those that encouraged discussion than those that distributed pamphlets.Conclusions Education interventions are effective in increasing the menstrual knowledge of young adolescent girls and skills training improves competency to manage menstruation more hygienically and comfortably. …”
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Systematic Review and Network Meta-Analysis on Treating Hormone Receptor-Positive Metastatic Breast Cancer After CDK4/6 Inhibitors by Neha Pathak, Abhenil Mittal, Sudhir Kumar, Chitrakshi Nagpal, Eitan Amir, Partha Haldar, Bharath B. Gangadharaiah, Akash Kumar, Ashutosh Mishra, Atul Batra

“…We calculated the hazard ratio (HR) for progression-free survival (PFS) and overall survival (OS) using generic inverse variance and odds ratios (ORs) using the Mantel–Haenszel method for adverse events (AEs) with Review-Manager version-5.4. NMA was executed using WINBUGS (Microsoft Excel). …”
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‘Everyone should know what they’re on’: a qualitative study of attitudes towards and use of patient held lists of medicines among patients, carers and healthcare professionals in p... by Caitriona Cahir, Kathleen E Bennett, Sheena M Mc Hugh, Ciara Kirke, Muriel Pate, Bernadine O'Donovan

“…Objectives Managing multiple medicines can be challenging for patients with multimorbidity, who are at high risk of adverse outcomes, for example, hospitalisation. …”
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Mental health and substance use among rehabilitation sciences students during the COVID-19 pandemic by Itumeleng Ntatamala, Saajida Khan, Zenzo Chakara

“…A mental health diagnosis in the past 12 months was significantly associated with alcohol use (AOR [adjusted odds ratio] = 4.02, 1.06–15.23), prescription medication used to manage academic/social stress (AOR = 5.74, 1.68–19.69), COVID-19 diagnosis (AOR = 5.51, 1.60–18.92) and physiotherapy programme (AOR = 12.35, 1.21–126.44). …”
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THE CONCEPT OF SELF-DETERMINATION IN THE PHILOSOPHY OF THE ENLIGHTENMENT by V. V. Khmil, O. M. Korkh

“…The philosophy of the Enlightenment has made a significant step toward further development of self-determination concept and its rationalization – separation of freedom and tyranny, new perception of necessary conditions for free self-determination of an individual as the ability to manage own passions and build own life on some rational principles, to refuse from excessive egoism, combining personal interests with the interests of others and public in generally these ideas were performed in the system of philosophical and legal liberalism, which emerged as a result of the synthesis of individualism and rationality concepts, and became an ideological basis for the modernization of Western civilization.…”
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Comparison of Effectiveness between Cobalt Chromium Rods versus Titanium Rods for Treatment of Patients with Spinal Deformity: A Systematic Review and Meta-Analysis by Frank D. Shega, HongQi Zhang, Daudi R. Manini, MingXing Tang, ShaoHua Liu

“…The demographic data and mean values of outcomes of interest were extracted from each group and compared by their mean difference as an overall outcome measure. The Review Manager software (RevMan 5.3) was utilized at a 95% significance level. …”
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Comparative efficacy of sleep positional therapy, oral appliance therapy, and CPAP in obstructive sleep apnea: a meta-analysis of mean changes in key outcomes by Yunjun Gao, Sixiang Zhu, Wenjun Li, Youqing Lai

“…However, SPT did not lead to significant improvements in TST or oxygen saturation parameters across comparisons.ConclusionSleep positional therapy (SPT) is a safe alternative for managing positional OSA, particularly for patients intolerant to CPAP, though it remains less effective than CPAP in reducing overall AHI and improving oxygenation.…”
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Web-based interventions for pregnant women with gestational diabetes mellitus: a systematic review and meta-analysis protocol by Ping Xu, Wei Zhang, Xiaojuan Wang, Dan Dan Chen, Pingping Guo, Yin Jin, Zhenzhen Xiang, Minna Mao, Qiong Zheng, Suwen Feng

“…Web-based interventions have been used to manage GDM because of the advantages of high accessibility and flexibility, but their effectiveness has remained inconclusive. …”
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Antimicrobial effect of silver diamine fluoride (SDF) in arresting dentine caries of permanent teeth: A Systematic review [version 1; peer review: 2 approved] by Mamata Hebbal, Albandri Mohammed Alowid, Praveen Jodalli, Shahad Saad Alkait, Ghadeer Ghalab Almutairi, Fatimah Salim Almufarji

“…Future research, including long-term clinical trials, is warranted to elucidate optimal dosage regimens and therapeutic approaches for the routine application of SDF in managing dental caries.…”
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Influence of No-Tillage on Soil Organic Carbon, Total Soil Nitrogen, and Winter Wheat (Triticum aestivum L.) Grain Yield by Peter Omara, Lawrence Aula, Elizabeth M. Eickhoff, Jagmandeep S. Dhillon, Tyler Lynch, Gwendolyn B. Wehmeyer, William Raun

“…Both experiments were managed under CT until 2010 and changed to NT in 2011. …”
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Association between Alpha- Klotho Protein, Calcium, and Phosphate concentrations in Adult Iraqi Patients with Beta-Thalassemia Major by Ahmed J. Kadhim, Hedef D. El-Yaseen, Ali M. Jawad

“…Alpha-Klotho protein is a protein that has anti-aging properties and is involved in several functions, including reducing oxidative stress, regulating energy metabolism through several routes, and managing calcium and phosphate metabolism. Objective: This study aimed to assess changes in calcium and phosphate levels, Alpha-Klotho protein concentration, and their associations with cardiac dysfunction in patients with Beta-thalassemia major. …”
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Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity by Wen-lin Pang, Wen-lin Pang, Tian-gang Li, Tian-gang Li, Yin-ying Wang, Yin-ying Wang, Li-yun Song, Li-yun Song, Li Li, Li Li, Xiao-ya Li, Xiao-ya Li, Yong Qiu, Yong Qiu, Zhong-shan Yang, Zhong-shan Yang

“…In addition, analysis of 16S rRNA gene sequencing indicated that SC reduced harmful bacterial populations, such as Proteobacteria, while simultaneously enhancing the levels of beneficial bacteria like Lactobacillus, thereby contributing to the improvement of UC pathology.ConclusionThis study highlights the therapeutic potential of SC in managing UC through its ability to attenuate inflammatory responses, restore intestinal barrier functionality, and modulate gut microbiota composition, which findings offer insights into potential strategies for advancing UC treatment.…”
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Fuzzy Logic Recommender Model for Housing by Emanuel G. Munoz, Jaime Meza, Sebastian Ventura

“…The recommendation system relies on fuzzy control to manage user preferences and select appropriate input data with which to test the model. …”
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Transcatheter edge to edge compared with surgery in older patients with degenerative mitral valve regurgitation by Gaspard Suc, Rebecca Hadjedj, Jules Mesnier, Skerdi Haviari, Marylou Para, Gregory Ducrocq, Dominique Himbert, Eric Brochet, My Lien Nguyen, Sophie Provenchere, Marina Urena, Bernard Iung

“…Conclusion Patients with severe primary MR treated with TEER experienced a higher rate of adverse events within one year compared to surgically managed patients. However, these differences were mainly associated to clinical characteristics and were no longer significant after adjustment on residual MR > 2. …”
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Excessive Weight Gain During Pregnancy Increased Ponoxarase 1 Level in Neonatal Cord Blood by Serhat Ege, Hasan Akduman, Ayşegül Aşır, Tuğcan Korak

“…Maternal obesity may specifically affect PON1 activity, potentially serving as a compensatory response to oxidative stress in neonates, suggesting PON1 as a possible biomarker for oxidative stress-related metabolic disturbances in neonates of obese mothers, with implications for monitoring and managing pregnancy outcomes in obese populations.…”
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Mapping the Gaps: A Scoping Review of Virtual Care Solutions for Caregivers of Children with Chronic Illnesses by Nicole Pope, Kathyrn A. Birnie, Melanie Noel, Justine Dol, Danyu Li, Megan Macneil, Darrel Zientek, Victoria Surry, Jennifer N. Stinson

“…Significant gaps were noted in interventions for managing caregiver chronic pain, despite its high prevalence and impact on child outcomes. …”
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CtBP1 is essential for epigenetic silencing of μ-opioid receptor genes in the dorsal root ganglion in spinal nerve ligation-induced neuropathic pain by Cheng-Yuan Lai, Ming-Chun Hsieh, Chou-Ming Yeh, Tzer-Bin Lin, Dylan Chou, Hsueh-Hsiao Wang, Kuan-Hung Lin, Jen-Kun Cheng, Po-Sheng Yang, Hsien-Yu Peng

“…Targeting the Foxp1/CtBP1/HDAC2/μ-opioid receptor signaling pathway in the DRG holds promise as a potential therapeutic strategy for managing neuropathic pain.…”
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