Chemical composition by PTP 1B inhibitory activity guided analysis of a plant- based antidiabetic polyherbal drug used in ethnomedical systems by Pardon Mugari, Pamhidzai Dzomba, Stephen Nyoni

“…Conclusion Presence of alkaloids and anthocyanins that have PTP 1B inhibitory activity showed that the polyherbal drug is a potential medicine for managing diabetes.…”
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Real world study on combining local interventions with systemic therapy in unresectable hepatocellular carcinoma by Zhaosong Xue, Ming Yao, Kang Chen, Taiyun Huang, Jianjun Li, Jian Chen, Fei Huang, Yubin Huang, Xiaoyong Cai, Yihe Yan

“…The triple therapy demonstrated favorable prognostic outcomes and manageable safety profiles in patients with initially unresectable HCC.…”
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Social and Travel Lockdown Impact Considering Coronavirus Disease (COVID-19) on Air Quality in Megacities of India: Present Benefits, Future Challenges and Way Forward by Suresh Jain, Tanya Sharma

“…All the experts said that reviving the economy will be a big challenge for the government, and it may result in some tradeoff while managing the air quality in the near future due to scarcity of funds, etc.…”
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Building Academic Integrity: Evaluating the Effectiveness of a New Framework to Address and Prevent Contract Cheating by Deepani B. Guruge, Rajan Kadel, Samar Shailendra, Aakanksha Sharma

“…Current approaches to managing contract cheating often lack the comprehensive structure needed to address the complexities of modern cheating methods. …”
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Obstacles and opportunities for care collaboration through the utilisation of a preventive care process for frail older adults: a study protocol for a mixed methods study design by Åsa Larsson Ranada, Elisabet Rothenberg, Helle Wijk, Martina Karin Boström, Pia Skott, Anette Erichsen

“…Additionally, 30 semi-structured individual interviews with residential care managers and other relevant stakeholders will explore obstacles and opportunities for effective care collaboration.Discussion We foresee that the results will contribute to the development of a model for effective PcP and care collaboration that can be used to improve patient safety and quality of care for frail older adults. …”
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“I surely don’t call for fun”: experiences of being a “frequent caller” to the Danish emergency helpline by Camilla Braendstrup Laursen, Tine Bennedsen Gehrt, Linda Huibers, Claus Bossen, Ulla Vaeggemose

“…Furthermore, we found that the sense of disorientation and the fragmentation of experience that is characteristic of “struggling along” made it difficult for our study participants to communicate with the Emergency Medical Coordination Center (EMCC) that manages all health-related calls to 1-1-2. Finally, our analysis pointed to differences in how the goal of providing “the right help at the right time” was understood by citizens and by health professionals working within the EMCC of the Prehospital Emergency Medical Services. …”
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Risk of stroke associated with proton pump inhibitor use among individuals with and without pre-existing cardiovascular diseases: a systematic review and meta-analysis by Muhammed Shabil, Bijaya K. Padhi, Mahalaqua Nazli Khatib, Soumya V. Menon, Mandeep Kaur, Mukesh Kumari, Puneet Sudan, K. Satyam Naidu, Quazi Syed Zahiruddin, Sarvesh Rustagi, Divya Sharma, Mithhil Arora, Rakesh Kumar Sharma, Edward Mawejje, Prakasini Satapathy, Sanjit Sah

“…Abstract Background Proton pump inhibitors (PPIs) are commonly used for managing gastroesophageal disorders but concerns about their potential association with increased stroke risk have emerged, especially among patients with pre-existing cardiovascular conditions such as acute coronary syndrome (ACS). …”
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Infectious outcomes of a standardized subcutaneous immunoglobulin dose reduction strategy in primary immune deficiencies amid global shortage by Pedro Moral Moral, Pedro Moral Moral, Marta Dafne Cabanero-Navalon, Marta Dafne Cabanero-Navalon, Paula Teresa López-León, Paula Teresa López-León, Héctor Balastegui-Martín, Héctor Balastegui-Martín, Sandra Martínez Mercader, Sandra Martínez Mercader, Amparo Mir, Victor Garcia-Bustos, Victor Garcia-Bustos, Victor Garcia-Bustos

“…IntroductionImmunoglobulin replacement therapy (IgRT), either intravenous (IVIg) or subcutaneous (SCIg), is crucial for managing primary immune deficiencies (PIDs) with hypogammaglobulinemia by reducing infection rates and mortality. …”
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Surgical Outcomes of a Second Ahmed Glaucoma Valve Implantation in Asian Eyes with Refractory Glaucoma by Sze Chuan Ong, Maria Cecilia Aquino, Paul Chew, Victor Koh

“…An additional AGV implant had good short and modest long-term effectiveness in reducing IOP following a failed glaucoma tube shunt in Asian eyes, with the mentioned common postoperative complications to be actively monitored and managed.…”
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Feasibility of home-based transcranial direct current stimulation combined with personalized word retrieval for improving naming in primary progressive aphasia by Allan George, Eric McConathey, Amy Vogel-Eyny, Elizabeth Galletta, Giuseppina Pilloni, Leigh Charvet

“…Background/ObjectivesPrimary progressive aphasia (PPA) is managed with speech-language therapy (SLT) to slow language decline. …”
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Association between fasting blood glucose and psychotic symptoms in Chinese patients with first-episode drug-naïve major depressive disorder by Xingzhi Xia, Hanxu Deng, Wei Ren, Lin Yang, Yingzhao Zhu, Yaozhi Liu, Junjun Liu, Xueli Zhao, Fengnan Jia, Xiangdong Du, Xiangyang Zhang

“…Conclusions Our investigation revealed a nonlinear relationship between FBG and PD in patients with FEDN MDD, thereby informing more effective intervention strategies for managing psychotic symptoms in individuals with depression.…”
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Comparison of three- and six-component scoring models for predicting the futility in cancer resuscitation: a retrospective study by A. Pramono, N. Maryani

“… INTRODUCTION: Palliative care is an approach to managing patients with critical illnesses who require the support of organ function from failure, in addition to those with chronic and terminal diseases including cancer that cannot be cured until rehabilitation. …”
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Dynamic analysis and comparison of the performance of linear and nonlinear controllers applied to a nonlinear non-interactive and interactive process by José M. Campos-Salazar, Pablo Lecaros, Rodrigo Sandoval-García

“…The results indicate that while the PI compensator and LQR provide satisfactory performance under linearized assumptions, the SMC demonstrates superior robustness and precision in managing the nonlinearities inherent in the IS configuration. …”
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The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells by Ali Fallah, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi, Ayyoob Khosravi, Azadeh Mohammad-Hasani, Azadeh Mohammad-Hasani, Mohsen Saeidi, Mohsen Saeidi

“…This study focused on exosomes derived from stem cells of human exfoliated deciduous teeth (SHED-MSC-EXOs) and their role in managing the balance of immunoregulatory macromolecules that play a role in the underlying immunoregulatory mechanisms in THP-1-derived M0/M1 macrophage cells.MethodsFlow cytometry confirmed the expression of CD14, CD68, CD80, and CD86 markers in these macrophages. …”
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Soil warming increases the active antibiotic resistome in the gut of invasive giant African snails by Yiyue Zhang, Hong-Zhe Li, Martin Breed, Zhonghui Tang, Li Cui, Yong-Guan Zhu, Xin Sun

“…These findings emphasize the urgent need for integrated environmental and health strategies to manage the rising threat of antibiotic resistance in the context of global climate change. …”
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The importance of field research in efficient water use in Kashkadarya region by Matyakubov B., Yakhyoev O., Karabayev A., Altmishev A.

“…It has been proven that irrigation water planning should be managed based on water evaporation. The average monthly amount of evaporation in Kashkadarya region was 5.16 mm, and the highest evaporation was observed in June and July, and the average annual precipitation was 111.4 mm. …”
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Deep-Learning-Based Land Cover Mapping in Franciacorta Wine Growing Area by Girma Tariku, Isabella Ghiglieno, Andres Sanchez Morchio, Luca Facciano, Celine Birolleau, Anna Simonetto, Ivan Serina, Gianni Gilioli

“…However, significant challenges remain in managing large, complex satellite imagery datasets, acquiring specialized datasets due to high costs and labor intensity, including a lack of comparative studies for the selection of optimal deep learning models. …”
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A Peculiar Cause of Shock: Analysing Two Clinical Cases by João Oliveira, Alberto Costa-Silva, Luís Vale, Daniel Costa, Rui Almeida-Pinto, Carlos Martins-Silva, Tiago Antunes-Lopes, João Silva

“…Clinicians should be wary of the possibility of this diagnosis when managing adrenal masses.…”
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Screening of <em>FecLL</em> prolific allele of the <em>B4GALNT2</em> gene in Algerian sheep populations by Assia Hadjazi, Fatima Zahra Belharfi, Fatima Zohra Mahammi, Stéphane Fabre, Semir Bechir Suheil Gaouar, Nacera Tabet-Aoul

“…Conclusions: The FecLL allele, which is shared by the French Lacaune population and the North African D’man populations, could indicate the ancestral origin of the mutation in B4GALNT2 or the occurrence of an ancient introgression event to improve prolificacy. Managing this mutation in Algerian D’man flocks could help improve the numerical productivity of D’man sheep in Algeria. …”
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Humoral and Cellular Immune Regulation in Albino Rat Exposed to Glyphosate and Aluminum Phosphide by Ujuamala Ezeani, Onyemaechi Afonne, Michael Ezeani

“…Background: Glyphosate (GLP) and Aluminum phosphide (ALP) pesticides remain vital for managing pests and disease vectors in both agriculture and public health. …”
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