Personalized Therapy in a Patient With EGFR-Mutated NSCLC Developing Sequential CCDC6-RET Fusion and BRAF V600E Mutation as Bypass Resistance Mechanisms by Arianna Marinello, MD, Claudia Parisi, MD, Damien Vasseur, PhD, David Combarel, PharmD, Juliette Bihoreau, NP, Pernelle Lavaud, MD, Rémy Ezzedine, MD, Lodovica Zullo, MD, Luc Friboulet, PhD, Gerard Zalcman, MD, PhD, Antoine Italiano, MD, PhD, Benjamin Besse, MD, PhD, Mihaela Aldea, MD, PhD

“…After the identification of CCDC6-RET fusion, the patient received a combination of selpercatinib and osimertinib with prolonged benefit and manageable toxicity. When a novel BRAF V600E mutation was detected at progression, the molecular tumor board suggested the administration of triple therapy, adding trametinib (anti-MEK). …”
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Consumer Labels can Convey Polyphenolic Content: Implications for Public Health by Andrew L. Waterhouse

“…A consumer label based on the major polyphenolic classes is both manageable and fairly informative as most foods do not contain all possible classes. …”
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Spiritual well-being in the 21st century: It is time to review the current WHO’s health definition by Francesco Chirico

“…Spirituality has received much interest in health care services; it can improve strategies for managing stress and can positively influence immune, cardiovascular (heart and blood vessels), hormonal, and nervous systems. …”
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Psychological Violence at Work: Problems in Applying the Law in Lithuania by Leščinskaitė Aistė

“…The recent amendments to the Labor Code also impose numerous obligations on employers to prevent psychological violence at work, which, together with the recommendations of the State Labor Inspectorate, have caused confusion not only in companies, institutions, and organizations, but also in the lives of their managers. The limited case law after the change in the legal framework shows that the legal framework is not working as it should and is not adequately interpreted to prevent psychological violence, and therefore deserves criticism.…”
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From the Guest Editors by Alberto d’Onofrio, Paola Cerrai, Alberto Gandolfi

“…At the same time, it is becoming quite evident thattraditional tools from biostatistics and bioinformatics cannot manage thesedata. Mathematics, theoretical biophysics and computer sciences are needed toqualitatively andquantitatively interpret experimental and clinical results, in order to makerealistic predictions.For more information please click the “Full Text” above.…”
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Modeling Passengers’ Boarding Behavior at the Platform of High Speed Railway Station by Tie-Qiao Tang, Yi-Xiao Shao, Liang Chen, Hua-Yan Shang

“…These results can help managers to understand the passengers’ boarding behavior and to improve the boarding efficiency.…”
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Application of Business Intelligence in the Brazilian Educational System by Carlos Grimm Moniz Junior, Tristão Sócrates Baptista Cavalcante, Adalena Kennedy Vieira, Raimundo Kennedy Vieira

“…From the construction of an integrated BI system, our study aimed to offer a helpful tool that was easy to handle and touched on visuals such as dashboards, tables, and graphs to help us understand and manage the educational scenery throughout Brazil. …”
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Massive Periacetabular Osteolysis Treated With Acetabular Cup Retention and Cemented Screw Fixation by Isabella T. Wu, MD, MPH, Cary S. Politzer, MD, Frank Chiarappa, MD, Scott T. Ball, MD

“…Management of periacetabular osteolysis is a challenging dilemma in revision total hip arthroplasty. …”
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academic libraries embrace Web access

“…Their efforts resulted in <a href="http://www.uce.ac.uk/tapin/">a mediation Model</a> for networked information. The project manager for <a href="http://www.uce.ac.uk/tapin/tapin2.htm">TAPin</a> reflects upon the importance of attitudes, infrastructure, staff skills, appearances and service practices in the process of change.…”
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Good Worker Health and Hygiene Practices: Training Manual for Produce Handlers by Amy Simonne, Jeffrey Brecht, Steve Sargent, Mark Ritenour, Keith Schneider

“… The goal of this first Edition of Good Worker Health and Hygiene Practices: Training Manual for Produce Handlers is to provide owners, managers, and/or supervisors in Florida's produce industry a training tool for their workers. …”
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Ecological movement in Baltic republics in the years of perestroika by A. K. Potapov

“…As a result, the Baltic intelligentsia who initiated discussion of these problems and managed to organize various protest actions gained some experience in mobilizing the population of the republics, which was then used in the creation of Popular Fronts and movements. …”
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Ecosystem Services Provided by Grass-legume Pastures by Jose C. B. Dubeux, Lynn E. Sollenberger, Mark Mauldin, Liza Garcia

“…., hunting, bird watching) and aesthetical ES. Grassland managers are providing these benefits to the entire society and they should receive compensation. …”
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Autonomie, responsabilité et coopération : ce qu’en disent les élèves utilisant un plan de travail by Sylvain Connac

“…If the teacher is constantly being sollicited by different problems, he or she feels quickly overwhelmed and is tempted to return to a traditional pedagogy, which is easier to manage. This research was interested in the opinions of Cycle III primary school students who practise daily work plans. …”
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The Airport Gate Assignment Problem: A Survey by Abdelghani Bouras, Mageed A. Ghaleb, Umar S. Suryahatmaja, Ahmed M. Salem

“…The airport gate assignment problem (AGAP) is one of the most important problems operations managers face daily. Many researches have been done to solve this problem and tackle its complexity. …”
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Prevention of Healthcare-associated Infections of Oncologic Patients by Lourdes Elizabeth Menéndez Oña, Gabriela Alejandra Valbuena Salazar, Gerardo José Sánchez Velásquez

“…Nursing is a profession that stands out as responsible for the control of hospital infection because, in addition to being able to manage the hospital environment, it is in greater contact with the patient. …”
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Predictive Value of Cardiovascular Global Risk Calculation by Cynthia Morales Pérez, Milagros Lisset León Regal, Rosmari Álvarez Hernández, Yudith Brito Pérez de Corcho, José Omar de Armas García, Alejandro Muñoz Morales

“…Among these 26 international impact articles from journals and a thesis, among other sources were reviewed, to which it was accessed through the main information managers. Risk mobility prediction has been an essential element in preventive clinical guidelines for these diseases and has become a useful tool for the family doctor, to set priorities in primary health care, which will allow making progress in studying complex associations that may impact cardiovascular risk.…”
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Kidney Disease and Youth Onset Type 2 Diabetes: Considerations for the General Practitioner by Allison B. Dart, Elizabeth A. Sellers, Heather J. Dean

“…A general understanding of this complex disease by primary care providers is critical, so that at-risk individuals are identified and managed early in the course of their disease, such that progression can be modified in this high-risk group of children and adolescents. …”
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Adaptive optimal control of prosumer energy storage system with renewable energy sources by D. V. Antonenkov, V. Z. Manusov, P. V. Matrenin, V. R. Kiushkina

“…The computer simulation has shown that the use of swarm algorithms makes it possible to increase the economic efficiency of managing the prosumer’s energy storage system by 2–4 times compared to the control rules manually constructed by an expert. …”
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The Economic Aspects of a Small Equine Boarding Operation in North Florida by Julie Gatlin, Johann Krebs, Peter J. van Blokland, John J. Haydu

“… Small property holders with lots of experience with horses might consider owning and managing a small equine boarding operation to supplement their income from permanent full-time jobs (Note: this type of operation will not sustain you by itself, nor is it recommended for someone unfamilar with caring for horses). …”
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« Think of your house as a watershed ! » La récupération des eaux de pluie à Tucson, en Arizona : vers la diversification de l’approvisionnement en eau dans le Sud-Ouest étasunien ... by Anne-Lise Boyer, Yves-François Le Lay

“…Our research questions the implementation of rainwater harvesting in Tucson (Arizona) and how it can modify the southwestern United States hydrosocial cycle based on large infrastructures and managed by powerful federal and state agencies. In the context of climate change, the hydrosocial cycle in Tucson is threatened by a water shortage on the Colorado River and has become therefore a controversial issue in the public debate. …”
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