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521
Genomic exploration of the journey of Plasmodium vivax in Latin America.
Published 2025-01-01“…Plasmodium vivax is the predominant malaria parasite in Latin America. Its colonization history in the region is rich and complex, and is still highly debated, especially about its origin(s). …”
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522
High Steroid Sensitivity among Children with Nephrotic Syndrome in Southwestern Nigeria
Published 2014-01-01“…The predominant histologic finding in resistant cases was focal segmental glomerulosclerosis (53.3%). No cases of quartan malaria nephropathy or hepatitis B virus nephropathy were diagnosed. …”
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523
Comparing the Trends of Vector-Borne Diseases (VBDs) before and after the COVID-19 Pandemic and Their Spatial Distribution in Southern Iran
Published 2023-01-01“…Pediculosis incidence trend was rising with a peak of 1,146 per 100,000 in 2018, followed by a dramatic decrease reached to the minimum amount of 157.8 per 100,000 in 2021. In contrast, malaria and scabies had a smooth decreasing trend ranging from 2.2 per 100,000 and 7.3 per 100,000 in 2016 to a minimum of 0.2 per 100,000 in 2021, respectively. …”
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524
Clustering Large-Scale Biomedical Data to Model Dynamic Accumulation Processes in Disease Progression and Anti-Microbial Resistance Evolution
Published 2025-01-01“…We demonstrate this ‘Cluster-based HyperHMM’ (CHyperHMM) pipeline for synthetic data, clinical data on disease progression in severe malaria, and genomic data for anti-microbial resistance evolution in Klebsiella pneumoniae, reflecting two global health threats.…”
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525
Study of Traditional Uses, Extraction Procedures, Phytochemical Constituents, and Pharmacological Properties of Tiliacora triandra
Published 2022-01-01“…The leaves and root extracts are used to treat gastrointestinal diseases, hypertension, diabetes, skin diseases, and malaria as an antipyretic, detoxification agent, anti-inflammatory, anticancer, and immunomodulator. …”
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526
Physiologically-based pharmacokinetic modeling of enantioselective hydroxychloroquine kinetics and impact of genetic polymorphisms
Published 2025-01-01“…Abstract Hydroxychloroquine (HCQ) is a chiral drug used to treat malaria and inflammatory diseases, available as a racemic mixture of R-and S-HCQ. …”
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527
Toxicity and Oviposition Deterrent Activities of Thyme Essential Oils against Anopheles arabiensis
Published 2021-01-01“…Background. Malaria is one of the deadliest mosquito-borne diseases in sub-Saharan Africa and Ethiopia. …”
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528
Visuals and text in pharmaceutical advertising: A multimodal analysis and ethical dilemmas
Published 2024-12-01“…Scholars also used a pragmatic approach to advertisements in Britain and Japan and conducted a multimodal discourse analysis of malaria drugs advertisement. However, the role of multimodality in the context of pharmaceutical advertising remains understudied. …”
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529
The Curative and Prophylactic Effects of Xylopic Acid on Plasmodium berghei Infection in Mice
Published 2013-01-01“…Efforts have been intensified to search for more effective antimalarial agents because of the observed failure of some artemisinin-based combination therapy (ACT) treatments of malaria in Ghana. Xylopic acid, a pure compound isolated from the fruits of the Xylopia aethiopica, was investigated to establish its attributable prophylactic, curative antimalarial, and antipyretic properties. …”
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530
Differential Gene Expression Profile of Human Neutrophils Cultured with Plasmodium falciparum-Parasitized Erythrocytes
Published 2018-01-01“…This response included a number of genes which are known to be involved in the pathogenesis of malaria and other inflammatory diseases. Gene enrichment analysis suggested that the biological pathways involved in the PMN responses to the iRBCs included insulin receptor, Jak-STAT signaling pathway, mitogen-activated protein kinase (MAPK), and interleukin and interferon-gamma (IFN-γ) signaling pathways. …”
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531
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532
Ethnopharmacology, Biological Evaluation, and Chemical Composition of Ziziphus spina-christi (L.) Desf.: A Review
Published 2022-01-01“…Biological reports and traditional applications including management of diabetes and treatment of malaria, digestive issues, typhoid, liver complaints, weakness, skin infections, urinary disorders, obesity, diarrhoea, and sleeplessness have all been treated with different parts of Z. spina all over the globe. …”
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533
Morbidity Cost and Willingness to Pay for Healthcare Insurance among Wheat Farmers in Jigawa State of Nigeria
Published 2024-03-01“…However, financial and, at worst, physical livelihood capitals posed challenges that affected farmers' livelihood assets in the study area. Furthermore, malaria emerged as the major health issue affecting livelihoods; consequently, slightly over half of the sampled population agreed to the notion of a social health insurance scheme for a healthy livelihood. …”
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534
A comparative analysis of the level of out-of-pocket healthcare expenditure in urban and rural communities in Edo state Nigeria
Published 2025-02-01“…Additionally, subsidizing the cost of medications, particularly for common illnesses like malaria, could significantly alleviate the burden of out-of-pocket healthcare expenditure. …”
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535
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536
A paradoxical population structure of var DBLα types in Africa.
Published 2025-02-01“…The implication of these local and pan-Africa population patterns is discussed in terms of advantage to the parasite with regards to within-host adaptation and resilience to malaria control.…”
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537
Amodiaquine and Ciprofloxacin Combination in Plasmodiasis Therapy
Published 2015-01-01“…Appropriate Amodiaquine and Ciprofloxacin combination will be effective for the treatment of malaria and better than either Amodiaquine or Ciprofloxacin singly at their recommended dosage levels.…”
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538
Evaluation of Halogenated Coumarins for Antimosquito Properties
Published 2014-01-01“…In the present study halogenated coumarins (3-mono/dibromo acetyl, 6-halogenated coumarin analogues) were screened for larvicidal, adulticidal, and repellent properties against Anopheles arabiensis, a zoophilic mosquito that is one of the dominant vectors of malaria in Africa. Five compounds exerted 100% larval mortality within 24 h of exposure. …”
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539
Mathematical Model Analysis and Simulation of Visceral Leishmaniasis, Kashgar, Xinjiang, 2004–2016
Published 2020-01-01“…Visceral leishmaniasis (VL), known as kala-azar, is a serious parasitic disease. After malaria, VL is the second largest parasitic killer. …”
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540
Reviewing the Past, Present, and Future Risks of Pathogens in Ghana and What This Means for Rethinking Infectious Disease Surveillance for Sub-Saharan Africa
Published 2022-01-01“…The topmost ID recorded in health facilities in Ghana transitioned from yaws in the 1890s to malaria in the 1950s through 2020. We then presented the hosts of a pathogen and the pathogens of a host, the administrative districts where a pathogen was found, and the pathogens found in each district of Ghana. …”
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