Structure-Function of Falcipains: Malarial Cysteine Proteases by Kailash C. Pandey, Rajnikant Dixit

“…Evidence indicates that cysteine proteases play essential role in malaria parasites; therefore an obvious area of investigation is the inhibition of these enzymes to treat malaria. …”
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Low Frequency of Asymptomatic and Submicroscopic Plasmodial Infections in Urabá Region in Colombia by Carolina Rodríguez Vásquez, Sebastián Barrera Escobar, Alberto Tobón-Castaño

“…Background. A screening for malaria parasites was conducted with asymptomatic residents in Colombia. …”
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Leveraging Global Fund’s investments to expand innovative public-private provider engagement in TB by M.A. Yassin, L. Kimbo, E. Wandwalo, A. Rashid, A. Dzokoto, U. Weber, G. Stallworthy

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Chemical Synthesis, Efficacy, and Safety of Antimalarial Hybrid Drug Comprising of Sarcosine and Aniline Pharmacophores as Scaffolds by Jean Baptiste Niyibizi, Peter G. Kirira, Francis T. Kimani, Fiona Oyatsi, Joseph K. Ng’ang’a

“…Malaria is a disease caused by protozoans transmitted to humans by infected female Anopheles mosquitoes. …”
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The impact of intermittent preventive treatment in school aged children with dihydroartemisinin piperaquine and artesunate amodiaquine on IgG response against six blood stage Plasm... by Eric Lyimo, Geofrey Makenga, Louise Turner, Thomas Lavstsen, John P A Lusingu, Jean-Pierre Van Geertruyden, Daniel T R Minja, Christian W Wang, Vito Baraka

“…Several interventional strategies have been implemented in malaria endemic areas where the burden is high, that include among others, intermittent preventive treatment (IPT), a tactic that blocks transmission and can reduce disease morbidity. …”
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Molecular Assessment of Domain I of Apical Membrane Antigen I Gene in Plasmodium falciparum: Implications in Plasmodium Invasion, Taxonomy, Vaccine Development, and Drug Discovery by Che Roland Achungu, Damian Nota Anong, Robert Adamu Shey, Cevie Jesenta Tabe

“…Given its global morbidity and mortality rates, malaria continues to be a major public health concern. …”
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Protective Effect of Aqueous Crude Extract of Neem (Azadirachta indica) Leaves on Plasmodium berghei-Induced Renal Damage in Mice by Voravuth Somsak, Sukanya Chachiyo, Ubonwan Jaihan, Somrudee Nakinchat

“…Malaria is a major public health problem in the world because it can cause of death in patients. …”
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Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome. by Lucy B Ochola, Bethsheba R Siddondo, Harold Ocholla, Siana Nkya, Eva N Kimani, Thomas N Williams, Johnstone O Makale, Anne Liljander, Britta C Urban, Pete C Bull, Tadge Szestak, Kevin Marsh, Alister G Craig

“…Our results show that increased binding to CD36 is associated with uncomplicated malaria while ICAM-1 adhesion is raised in parasites from cerebral malaria cases.…”
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Exploring the Infectious Drug Target Glutathione S-Transferase in Plasmodium falciparum with the Inhibitory Potential of Azadirachta indica Phytocompounds by Esam S. Al-Malki

“…Neem compounds are being studied for their potential as new and effective antimalarial drugs, and there is mounting evidence that they may help treat malaria. The PfGST enzyme is crucial to the malaria parasite’s survival, making it a desirable target for new antimalarial drugs, and the study aims to examine the bark region compounds as PfGST inhibitors. …”
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YAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates by Inés Bouzón-Arnáiz, Mukul Rawat, Rachael Coyle, Lionel Brice Feufack-Donfack, Malen Ea, Agnes Orban, Jean Popovici, Lucía Román-Álamo, Antonino Nicolò Fallica, Bárbara Domínguez-Asenjo, Javier Moreno, Elsa M. Arce, Ana Mallo-Abreu, Diego Muñoz-Torrero, Marcus C. S. Lee, Xavier Fernàndez-Busquets

“…Tests performed in clinical isolates indicated that YAT2150 had also strong activity against Plasmodium vivax (IC50 between 4 and 36 nM) and Leishmania infantum (1.27 and 1.11 µM), placing it as a unique compound with perspectives of becoming the first drug to be used against both malaria and leishmaniasis.…”
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Monitoring of Insecticide Resistance in Anopheles culicifacies in Twelve Districts of Madhya Pradesh, Central India (2017–2019) by Ashok K. Mishra, Praveen K Bharti, Gyan Chand, Aparup Das, Himanshu Jayswar, Manju Rahi, Kamaraju Raghavendra

“…Indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs) are malaria vector control measures used in India, but the development of insecticide resistance poses major impediments for effective vector control strategies. …”
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Review of Anopheles Mosquito Species, Abundance, and Distribution in Ethiopia by Fasil Adugna, Melaku Wale, Endalkachew Nibret

“…Plasmodium falciparum and P. vivax are the two malaria-causing parasitic species commonly known to cause human malaria in Ethiopia. …”
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Application of a targeted amplicon sequencing panel to screen for insecticide resistance mutations in Anopheles darlingi populations from Brazil by Holly Acford-Palmer, Alice O. Andrade, Jody E. Phelan, Rosa A. Santana, Stefanie C. P. Lopes, Jansen F. Medeiros, Taane G. Clark, Maisa S. Araujo, Susana Campino

“…Abstract Large-scale surveillance and informed vector control approaches are urgently needed to ensure that national malaria programs remain effective in reducing transmission and, ultimately, achieving malaria elimination targets. …”
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Relatively Low Prevalence of Peripheral and Placental Plasmodium Infection at Delivery in Bangui, Central African Republic by Alexandre Manirakiza, Eugène Serdouma, Djibrine Djalle, Georges Soula, Remi Laganier, Nestor Madji, Methode Moyen, Alain Le Faou, Jean Delmont

“…The aim of this study was to estimate the prevalence of malaria among women giving birth in Bangui. Association between sociodemographic characteristics of those women and malaria, as well as prevention compliance (use of intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTsp) and insecticide-treated bed nets (ITNs)), was analyzed. …”
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Antibody response to Plasmodium vivax in the context of Epstein-Barr virus (EBV) co-infection: A 14-year follow-up study in the Amazon rainforest. by Luiz F F Guimarães, Bárbara A Rodrigues, Michelle H F Dias, Matheus G Barcelos, Maria F A Nascimento, Sâmick L Moreira-Nascimento, Sofia L Afonso, Barbara G S Abreu, Jaap M Middeldorp, Francis B Ntumngia, John H Adams, Camila Fabbri, Stefanie Lopes, Cor J F Fernandes, Flora S Kano, Luzia H Carvalho

“…<h4>Background</h4>To develop an effective vaccine against Plasmodium vivax, the most widely dispersed human malaria parasite, it is critical to understand how coinfections with other pathogens could impact malaria-specific immune response. …”
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High School Students Are a Target Group for Fight against Self-Medication with Antimalarial Drugs: A Pilot Study in University of Kinshasa, Democratic Republic of Congo by Ramsès Kabongo Kamitalu, Michel Ntetani Aloni

“…To assess the self-medication against malaria infection in population of Congolese students in Kinshasa, Democratic Republic of Congo (DRC). …”
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Asymptomatic Plasmodium Parasites among Adults in Eastern Uganda: A Case of Donor Blood Screening at Mbale Regional Blood Bank by Simon Peter Inyimai, Mosses Ocan, Benjamin Wabwire, Peter Olupot-Olupot

“…The 1.3% prevalence of Plasmodium malaria parasites in screened donor blood units represents risk of malaria blood transfusion transmitted infection and a pool of community transmittable malaria infections, respectively.…”
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Experimental Immunization Based on Plasmodium Antigens Isolated by Antibody Affinity by Ali N. Kamali, Patricia Marín-García, Isabel G. Azcárate, Antonio Puyet, Amalia Diez, José M. Bautista

“…Vaccines blocking malaria parasites in the blood-stage diminish mortality and morbidity caused by the disease. …”
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Presence of the Anopheles culicifacies complex species A in southeast Iran by Seyed Massoud Madjdzadeh, Nahid Behi, Mohammad Amin Gorouhi, Arsalan Amirkafi, Mohammad Ali Oshaghi

“…Abstract Background The Anopheles culicifacies complex is one of the most important malaria vectors in Southeast Asia and Southeastern Iran. …”
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Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya by Victor Osoti, Kevin Wamae, Leonard Ndwiga, Paul M. Gichuki, Collins Okoyo, Stella Kepha, Kibor Keitany, Regina Kandie, Stephen Aricha, Rosebella Kiplagat, Charles Mwandawiro, Philip Bejon, Robert W. Snow, Lynette Isabella Ochola-Oyier

“…Abstract Background To understand the emergence and spread of drug-resistant parasites in malaria-endemic areas, accurate assessment and monitoring of antimalarial drug resistance markers is critical. …”
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