Effects of vitamin D supplementation in patients with rheumatoid arthritis: A systematic review and meta-analysis by Mahsa Ranjbar, Mehran Rahimlou, Maryam Fallah, Kurosh Djafarian, Hamed Mohammadi

“…The results indicate a major influence of vitamin D supplementation on the Disease Activity Score 28 (DAS-28) (WMD: −0.83, 95 % CI: −1.38 to −0.28, p-value <0.001), C-reactive protein (CRP) level (WMD: −0.24, 95 % CI: −0.45 to −0.03, p-value = 0.03), erythrocyte sedimentation rate (ESR) level (WMD: −4.08, 95 % CI: −4.67 to −3.50, p-value <0.001), serum vitamin D level (WMD: 12.69, 95 % CI: 1.80 to 23.59, p-value = 0.02), and non-significant effect on the health assessment questionnaire (HAQ) and visual analog scale on pain (VAS-pain) scores. …”
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Developing and assessing the “MultiLife” intervention: a mobile health-based lifestyle toolkit for cardiometabolic multimorbidity in diabetes and hypertension management – a type 1... by Sanghamitra Pati, Jaideep Menon, Tanveer Rehman, Ritik Agrawal, Jayasingh Kshatri, Subrata Kumar Palo, Chandrashekar Janakiram, Srijeeta Mitra, Aswathy Sreedevi, Tanu Anand

“…Abstract Background Cardiometabolic multimorbidity (CMM), characterized by the coexistence of diabetes, hypertension, and cardiovascular disease, poses a major health challenge in India, particularly in rural areas with limited healthcare resources. …”
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In Silico Identification of New Anti-SARS-CoV-2 Main Protease (Mpro) Molecules with Pharmacokinetic Properties from Natural Sources Using Molecular Dynamics (MD) Simulations and Hi... by Harrison Onyango, Patrick Odhiambo, David Angwenyi, Patrick Okoth

“…However, these drugs majorly act to reduce the symptoms of the disease. …”
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Individual and community level maternal factors for zero-dose children in Ethiopia using mini-EDHS 2019: a mixed effects model by Anteneh Kassa Yalew, Werkneh Melkie Tilahun, Meron Asmamaw Alemayehu, Tigabu Kidie Tesfie, Muluken Chanie Agimas, Mekuriaw Nibret Aweke, Worku Necho Asferie, Moges Tadesse Abebe

“…Globally, zero-dose children are the major public health problem. In sub-Saharan African countries, one among five children do not have access to vaccines. …”
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Peranan Kadar Feritin Serum terhadap Kejadian Preeklampsia by Mega Ulfah, Masrul , Arni Amir

“…<br />Kata kunci: preeklampsia, hipertensi dalam kehamilan, serum feritin</p><p> </p><p>Abstract <br />Preeclampsia is a major cause of worldwide maternal and prenatal mortality. …”
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Medico-ethnobotanical survey of medicinal plants used in the treatment of skin diseases in Tiruppur District, Tamil Nadu, India by Prakasam Radha, Chinniaya Udhayavani, Raju Nagaraj, Kumarasamy Sivaranjani

“…Out of which, herbs constitute the major portion with 31 species used for skin ailments. …”
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Experimental study on strength degradation and meso-structural characteristics of saturated sandstone under freeze-thaw cycles by Haotian XIE, Ying XU, Qiangqiang ZHENG, Meilu YU, Shoudong XIE, Chengjie LI

“…Freeze-thaw damage to rock masses on slopes constitutes a major hazard in open-pit mining operations, particularly in the cold regions of the western area. …”
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Intracranial CT findings in traumatic brain injury: A retrospective, cross-sectional study among Igbo population in Nigeria by Angel-Mary Anakwue, Felicitas Ugochinyere Idigo, Uloma Benedicta Nwogu, Sylvester Osita Ogbu, Anthony Nnamani, Kennedy Joseph, Camillus Chukwuemeka Ugwoke

“…Introduction: Traumatic brain injury (TBI) is a major cause of death and disability and in recent years has been increasingly reported even in developing countries. …”
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Psychological detachment from work predicts mental wellbeing of working-age adults: Findings from the 'Wellbeing of the Workforce' (WoW) prospective longitudinal cohort study. by Holly Blake, Juliet Hassard, Louise Thomson, Wei Hoong Choo, Teixiera Dulal-Arthur, Maria Karanika-Murray, Lana Delic, Richard Pickford, Lou Rudkin

“…<h4>Results</h4>Risk for major depression (T1: 20.0% to T2: 29.0%, p = .002), poor general health (T1: 4.7% to T2: 0%, p = .002) and poor life satisfaction (T1: 15.4% to T2: 25.4%, p = .002) worsened over time, moderate-to-severe anxiety remained stable (T1: 26.1% to T2: 30.2%, p = .15). …”
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Impact of cooking on nutritional contents of kenger in terms of antioxidants by Indrani Kalkan, Ozan Emre Eyupoglu, Sukru Karatas, Zakia El Miri Aissaoui, Rusen Anık

“…Vitamin C was quantified using HPLC and antioxidant activities were assessed by DPPH inhibition, ABTS and FRAP methods. Major phenolic compounds in raw samples were vanillic (18.755 ± 0.606 µg/g) and fumaric (16.211 ± 0.524 µg/g) acids. …”
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An Analysis of the Gear Meshing Characteristics of the Main Planetary Gear Trains of Helicopters Undergoing Shafting Position Changes by Li Xuejun, Jiang Lingli, Hua Dengrong, Yin Daoxuan, Yang Dalian

“…This study’s research findings will provide a theoretical basis for future operational status monitoring of the main transmission systems of helicopters and are of major significance for improvements in the operational stability of helicopter transmission systems, which will potentially ensure safe and efficient operations.…”
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Selective and persistent toxicity of seven insecticides to five egg parasitoids of Spodoptera frugiperda by Hao-Ran Li, Cheng-Yang Li, Peng Dai, Lian-Sheng Zang, Nicolas Desneux, Wei Xu

“…Abstract Background Spodoptera frugiperda, a major migratory and invasive pest, inflicts significant yield loss on rice and maize in China. …”
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Secukinumab in the treatment of psoriatic arthritis: efficacy and safety results through 3 years from the year 1 extension of the randomised phase III FUTURE 1 trial by Philip J Mease, Arthur Kavanaugh, Andreas Reimold, Hasan Tahir, Jürgen Rech, Stephen Hall, Piet Geusens, Pascale Pellet, Evie Maria Delicha, Shephard Mpofu, Luminita Pricop

“…Exposure-adjusted incidence rates for selected adverse events per 100 patient-years (secukinumab 150/75 mg) were serious infections (1.7/1.6), Candida infections (1.4/0.7), Crohn’s disease (0/0.3), ulcerative colitis (0/0.3) and major adverse cardiac events (0.3/0.8).Conclusion Subcutaneous secukinumab provided sustained improvements in the signs and symptoms, quality of life and physical function of patients with active PsA with low rate of radiographic disease progression through 3 years. …”
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Correlation between the Serum Platelet-Derived Growth Factor, Angiopoietin-1, and Severity of Coronary Heart Disease by Sisi Pang, Zhengxian Tao, Xiaoyan Min, Chuanwei Zhou, Dijia Pan, Zhen Cao, Xiangming Wang

“…Patients with ACS were followed up, and the major adverse cardiovascular and cerebrovascular adverse events were recorded. …”
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Missed opportunity for nasal continuous positive airway pressure in preterm neonates admitted at a tertiary-level hospital newborn unit in Kenya: a mixed method study by Florence Murila, Peace Kakibibi, Diana Marangu-Boore

“…It remains one of the major public health concerns that contribute to neonatal mortality and morbidity, especially in Africa, where 80% of neonatal mortality is estimated to be caused by preterm complications. …”
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Royal Jelly and 10-Hydroxy-2-Decenoic acid activate autophagy through mTOR/ULK1 pathway to improve cognitive function in diabetic mice by Lu Xiu, Rongguang Ge, Siyu Lu, Linwei Li, Wenqi Huang, Guojun Du, Zengli Zhang, Jie Zhang, Zhongxiao Wan, Jie Chang

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Incremental Lifetime Cancer Risk of PAHs in PM2.5 via Local Emissions and Long-Range Transport during Winter by Shahzada Amani Room, Chia En Lin, Shih Yu Pan, Ta Chih Hsiao, Charles C.-K. Chou, Kai Hsien Chi

“…Our results indicated that vehicle emissions (gasoline engines: 20.8%, diesel engines: 23.3%) and coal combustion (55.9%) were the major sources of PAHs in the urban site, with higher levels in LP than in LRT. …”
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Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets by Huahua Li, Lingling Zou, Zhaowei Long, Junkun Zhan, Junkun Zhan

“…BackgroundType 2 Diabetes Mellitus (T2DM) represents a major global health challenge, marked by chronic hyperglycemia, insulin resistance, and immune system dysfunction. …”
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Effects of exercise dose based on the ACSM recommendations on depression in hemodialysis patients: a systematic review and meta-analysis of randomized controlled trials by Yang Fang, Yang Fang, Bai Xiaoling, Li Huan, Li Huan, Guan Yaping, Zhang Binying, Wang Man, Wu Juan, Liu Xinyu

“…ObjectiveTo explore the impact of various exercise doses on depressive symptoms among hemodialysis patients and offer valuable guidance for the selection of optimal exercise doses in clinical practice settings.MethodsA comprehensive systematic review was conducted across four major databases, namely, PubMed, Embase, Web of Science, and Cochrane Library, covering the period from their inception until August 2024. …”
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Tuberculosis and Sudden Death in Lithuania by Gintarė Zarembaitė, Gabrielė Žiūkaitė, Sigitas Chmieliauskas, Diana Vasiljevaitė, Sigitas Laima, Jurgita Stasiūnienė

“…Conclusions: Tuberculosis remains a major problem in Lithuania and the combination of socioeconomic indicators determines the prevalence of tuberculosis in the country. …”
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