Management of Irritable Bowel Syndrome: Novel Approaches to the Pharmacology of Gut Motility by Carmelo Scarpignato, Iva Pelosini

“…As a consequence, drugs affecting gastrointestinal (GI) motility have been widely employed with the aim of correcting the major IBS manifestations, ie, pain and altered bowel function. …”
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CO2 methanation over low-loaded Ni-M, Ru-M (M = Co, Mn) catalysts supported on CeO2 and SiC by Chopendra G. Wasnik, Maki Nakamura, Taiki Shimada, Hiroshi Machida, Koyo Norinaga

“…The concentration of the major greenhouse gas CO2 is rapidly increasing in the atmosphere, leading to global warming and a range of environmental issues. …”
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Temporospatial Variation, Chemical Composition, and Source Resolution of PM2.5 in the Southeastern Taiwan Island by Chung-Shin Yuan, Jun-Hao Ceng, Po-Hsuan Yen, Kuan-Chen Chiang, Yu-Lun Tseng, Kwok-Wai Wong, Ming-Shiou Jeng

“…Trajectory simulation indicated that high PM2.5 concentrations were mostly originated from North and Central China, Japan islands, and Korea Peninsula. Major sources of PM2.5 resolved by CMB receptor modeling were ordered as: sea salts (19.9%) > fugitive dust (19.8%) > industrial boilers (oil-fired) (10.8%) > secondary sulfate (9.8%) > mobile sources (8.0%).…”
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Factors affecting the prolongation of mechanical ventilation in patients after cardiac surgery by Mahdieh Sharifzadeh Kermani, Tania Dehesh, Shiva Pouradeli, Bahareh Soltani Esmaili

“…Abstract Background This study aimed to investigate the major predictive factors associated with prolonged mechanical ventilation(PMV) following cardiac surgery. …”
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Comparative effectiveness of manual therapy, pharmacological treatment, exercise therapy, and education for neck pain (COMPETE study): protocol of a systematic review with network... by Ana Izabela Sobral de Oliveira-Souza, Jordana Barbosa-Silva, Douglas P. Gross, Bruno R. da Costa, Nikolaus Ballenberger, Tiago V. Pereira, Liz Dennett, Susan Armijo-Olivo

“…NMAs will be conducted to rank interventions according to their effectiveness and safety (when possible), allowing a comprehensive analysis of all available evidence, with different nodes specified for all conservative interventions of interest, placebo, sham therapy, and non-intervention control. Major findings/summary of interpretations/conclusions This NMA will help clinicians and the scientific community choose the most effective strategy or combinations of strategies for treating neck pain. …”
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High-risk fertility behavior and associated factors among mothers attending antenatal care at public health facilities in Hossana Town, Central Ethiopia Region: facility based cros... by Yishak Sinebo, Tekle Ejajo, Awoke Girma, Tadele Yohannes

“…Having ANC follows- up, number of ANC visits, and knowledge on contraception were the major factors affecting HRFB. HRFB could seriously indicate the development of the country as well as maternal health issues. …”
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Antimicrobial and antioxidant study of combined essential oils of Anethum Sowa Kurz. and Trachyspermum ammi (L.) along with quality determination, comparative histo-anatomical feat... by S.A. Wasim Akram, Mary Shamya Arokiarajan, J. John Christopher, Mohammad Jameel, Mohd Saquib, Tirumala Santosh Kumar Saripally, Noman Anwar, Mohd Asif, Kabiruddin Ahmed K

“…GC-MS study of hydro-distillate exhibited presence of monoterpenic cyclic and aromatic hydrocarbons, alcoholic and ketonic groups along with phenolic derivative that covers majorly 90% of total metabolites. Combined essential oils (EOs 1 + 2) of both fruits showed excellent antimicrobial activity against various clinical pathogenic strains such as K. pneumoniae at 10 µL/mL, S. aureus at 2.5 µL/mL, E. coli and E. faecalis at 1.25 µL/mL, and MRSA and Bcereus at 0.625 µL/mL and (C) albicans at 0.312 µL/mL as the MIC. …”
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Socioeconomic inequality in hypertension and its determinants in people over 60 years in Fasa, southern Iran: a Blinder-Oaxaca decomposition by Reza Tabrizi, Reza Pakzad, Maryam Akbari, Azizallah Dehghan, Mozhan Abdollahi, Sina Bazmi, Sina Kardeh, Yaser Sarikhani

“…Abstract Background Hypertension (HTN) is well-known as a major risk factor for various noncommunicable diseases. …”
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Spatiotemporal Variations of Particulate Matter and their Association with Criteria Pollutants and Meteorology in Malaysia by Anis Asma Ahmad Mohtar, Mohd Talib Latif, Doreena Dominick, Maggie Chel Gee Ooi, Azliyana Azhari, Nor Hafizah Baharudin, Norfazrin Mohd Hanif, Jing Xiang Chung, Liew Juneng

“…The PCA analysis indicates that the major sources leading to the formation of particulate matter are from the contribution of secondary aerosols and combustion-related sources. …”
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Comparison of Accounting Profit Between Offshore and Deep-sea Commercial Fishing Industry in Pahang State, East Coast of Peninsular Malaysia by Moe Shwe Sin, Lavaniya Gopabala Krishnan, Shzee Yew Tai, Azlina Abd Aziz, Mahirah Kamaludin

“…The commercial fishing industry in East Coast of Peninsular Malaysia are mainly operated by trawlers and purse seines which rises a major concern in managing and achieving the goal of sustainable fishery. …”
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Global, regional, and national burdens of type 1 and type 2 diabetes mellitus in adolescents from 1990 to 2021, with forecasts to 2030: a systematic analysis of the global burden o... by Xing Chen, Luying Zhang, Wen Chen

“…Abstract Background Adolescent diabetes is one of the major public health problems worldwide. This study aims to estimate the burden of type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in adolescents from 1990 to 2021, and to predict diabetes prevalence through 2030. …”
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Isolation of Extended-Spectrum β-lactamase- (ESBL-) Producing Escherichia coli and Klebsiella pneumoniae from Patients with Community-Onset Urinary Tract Infections in Jimma Univer... by Mengistu Abayneh, Getnet Tesfaw, Alemseged Abdissa

“…Klebsiella pneumoniae and Escherichia coli are the major extended-spectrum β-lactamase- (ESBL-) producing organisms increasingly isolated as causes of complicated urinary tract infections and remain an important cause of failure of therapy with cephalosporins and have serious infection control consequence. …”
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Cardiovascular health in breast cancer patients: insight on BRCA1/2 mutations impact by Panagiotis Mallios, Mehdi Dehghan Manshadi, Laila Hubbert, Tajeri Aydin, Claudia Maes, Johanna Rantala, Annelie Liljegren, Narsis A. Kiani, Elham Hedayati

“…Heart failure (HF) was the most common major adverse cardiovascular event (MACE), affecting 4.6% of BRCA-BC and 9.5% of Sporadic-BC patients. …”
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The study of miRNA-211 affects melanogenesis progress in Cashmere goats via suppressing <i>AP1S2</i> by B. Zhang, R. Liu, T. Ma, X. Li, Y. Zhao, H. Su, J. Li, Y. Li, H. Jiang, Q. Zhang

“…<p>Chromaticity is a key indicator of measuring economic worth of Cashmere goats, and gene regulation plays a major role in Cashmere goat color. By targeting the 3<span class="inline-formula">^′</span>UTR region of genes, such as miRNA-211, miRNA plays a significant regulatory role in melanogenesis. …”
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Chemical Composition Characteristics and Source Apportionment of PM2.5 in Ceramic Industrial Base during Winter by Xiang Tu, Xiaozhen Fang, Hansun Fang, Changlin Ye, Zugen Liu, Xuehui Jia, Dan He, Jinliang Wang, Hong Huang, Changwei Zou, Chenglong Yu

“…The study reported herein describes an effort to ascertain the degree and sources of the PM2.5 collected in a ceramic industrial base during winter. The major chemical components in PM2.5 were analyzed, including carbonaceous aerosols, water-soluble ions, and inorganic elements. …”
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The efficacy and safety of Vonoprazan and Tegoprazan in eradication: a comprehensive systematic review and meta-analysis of randomized controlled trials by Ting Jin, Wei Wu, Lei Zhang, Han Xuan, Haixiang Zhang, Li Zhong

“…Data sources and methods: Comprehensive searches were conducted in major databases, including PubMed, Embase, the Cochrane Library, and Web of Science, up to January 1, 2024. …”
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E-HEART score: A novel scoring system for undifferentiated chest pain in the emergency department by V. Yuvaraj, Sachin Sujir Nayak, S. Vimal Krishnan

“…The primary endpoint was the occurrence of major adverse cardiovascular events (MACE) within 4 weeks of initial presentation. …”
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Understanding Citizens’ Response to Social Activities on Twitter in US Metropolises During the COVID-19 Recovery Phase Using a Fine-Tuned Large Language Model: Application of AI by Ryuichi Saito, Sho Tsugawa

“…ObjectiveThis study aimed to explore the sentiments of residents of major US cities toward restrictions on social activities in 2022 during the transitional phase of the COVID-19 pandemic, from the peak of the pandemic to its gradual decline. …”
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A common mechanism of detoxification for lambda-cyhalothrin and abamectin in Cydia pomonella by Di Ju, Chao Hu, Peirong Li, Ping Gao, Yuting Li, Xueqing Yang

“…The activities of detoxification enzymes increased after insecticide exposures, indicating that the detoxification of LCT was primarily carried out by P450 and CarE enzymes, while P450 and GST enzymes played a major role in the detoxification of AM. A total of 72 P450 genes and 75 CarE genes were identified in the C. pomonella transcriptome, with 43 of these genes (including 11 P450, 3 GST, 10 CarE, 11 ABC transporters, and 8 UDP-glycosyl transferases) being over-expressed in response to both insecticides Interestingly, ABC transporters were predominantly induced by AM treatment, while GST showed higher induction levels with LCT treatment. …”
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Identification of Five m6A-Related lncRNA Genes as Prognostic Markers for Endometrial Cancer Based on TCGA Database by Li Shan, Ye Lu, Cheng-Cheng Xiang, Xiaoli Zhu, Er-Dong Zuo, Xu Cheng

“…GSEA showed that “MITOTIC SPINDLE and other pathways” were more enriched in cluster 1. Five major lncRNAs associated with m6A were screened out, and risk score modeling was used for UCEC prognosis prediction. …”
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