A meta-analysis of MHC diversity in Pan troglodytes verus by Christelle Vangenot, Alicia Sanchez‑Mazas

“…We performed a meta-analysis of the Major Histocompatibility Complex (MHC) diversity for locus A, B, C, DQB1, DPB1 and DRB1 in Chimpanzees by selecting cohorts of animals for which MHC genotypes were available in publications and by extracting DNA sequences available on the IPD-MHC database. …”
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Profiles and natural drivers of antibiotic resistome in multiple environmental media in penguin-colonized area in Antarctica by Yongpeng Zhang, Bo Zhang, Imtiaz Ahmed, Hanshu Zhang, Yiliang He

“…These findings highlight the major roles of natural drivers (e.g., MGEs and penguins) in shaping environmental antibiotic resistome in polar areas, improving our understanding of the evolution of environmental microbiome.…”
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Relationship between physical activity during pregnancy and maternal health outcomes: evidence from the MAASTHI cohort study in Bengaluru, India by Yamuna Ana, Floor A. van den Brand, Onno C. P. van Schayck, Giridhara R. Babu

“…BackgroundSedentary behavior is one of the major modifiable behavioral risk factors for non-communicable diseases. …”
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Metabolic Performance of Mealworms and Black Soldier Fly Larvae Reared on Food and Agricultural Waste and By-Products by Frederik Kjær Nielsen, Rasmus Juhl Hansen, Asmus Toftkær Muurmann, Simon Bahrndorff, Niels Thomas Eriksen

“…We reared mealworms and BSF larvae on a diverse selection of by-products from agricultural and food industries, quantified major metabolic rates across their life spans, and compared their performances. …”
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Hubungan Pelaksanaan Strategi Directly Observed Treatment Short Course dengan Hasil Pengobatan Tuberkulosis Paru Puskesmas Padang Pasir Kota Padang 2011-2013 by Nurmadya ., Irvan Medison, Hafni Bachtiar

“…<br />Kata kunci: tuberkulosis paru, DOTS, hasil pengobatan</p><p>Abstract<br />Tuberculosis (TB) remains a major problem pulmonary global health in the world. …”
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Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors by null Chunyan-Zou, null Yanpeng-He, null Changshun-Xie, null Fulai-Gao, null Xiaoli-Xie, null Xiukun-Chai, null Chenxi-He, null Dongqiang-Zhao

“…GO analysis results revealed that DEGs were involved in negative management of myocardial contraction, regulation of myocardial cell contraction, ethanol oxidation, cellular potassium ion homeostasis, and relaxation of cardiac muscle, and KEGG analysis showed that major DEGs were with cGMP-PKG signaling pathway. …”
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Criminal justice in a small Nordic country: The case of Iceland by Helgi Gunnlaugsson

“…As it turns out, the Icelandic prison system has undergone major changes to meet this penal challenge. A new modern prison has recently been built close to Reykjavík to replace three smaller, older facilities that have been closed. …”
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Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program. by Allison E Ashley-Koch, Nathan A Kimbrel, Xue J Qin, Jennifer H Lindquist, Melanie E Garrett, Michelle F Dennis, Lauren P Hair, Jennifer E Huffman, Daniel A Jacobson, Ravi K Madduri, Hilary Coon, Anna R Docherty, Jooeun Kang, Niamh Mullins, Douglas M Ruderfer, VA Million Veteran Program (MVP), MVP Suicide Exemplar Workgroup, International Suicide Genetics Consortium, Philip D Harvey, Benjamin H McMahon, David W Oslin, Elizabeth R Hauser, Michael A Hauser, Jean C Beckham

“…The genetic correlation of SI and SA within MVP was high (rG = 0.87; p = 1.09e-50), as well as with post-traumatic stress disorder (PTSD; rG = 0.78; p = 1.98e-95) and major depressive disorder (MDD; rG = 0.78; p = 8.33e-83). …”
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Isotype diversity of antibodies specific for component allergens in the context of allergic diseases: eosinophilic esophagitis (EoE), asthma, and the alpha-gal syndrome (AGS) by Thomas A. E. Platts-Mills, Matthew H. MacCallum, Jeffrey M. Wilson, Lisa J. Workman, Elizabeth A. Erwin

“…Secondly, several different allergic diseases or phenomena have been identified in which isotype diversity of the antibodies has become a major issue. Prior to 1990 only occasional cases of eosinophilic esophagitis (EoE) had been identified, but since then they have become common. …”
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Characterising melanoma diagnostic pathways for patients in routine practice using administrative health data in Ontario, Canada: a population-based study by Frances C Wright, Timothy P Hanna, Patti A Groome, Nicole J Look Hong, Meaghan E Mavor, Yuka Asai, Hugh Langley

“…A higher proportion in the ‘primary care only’ pathway lived in rural areas whereas a higher proportion in the ‘referred to specialist for immediate action’ and the ‘specialist care only’ pathways lived in major urban centres. Across pathways, the median DI varied from 1 to 67 days, the median primary care subinterval varied from 1 to 30 days and the median specialist care subinterval varied from 1 to 25 days. …”
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Chicken C4BPM facilitates replication of H5N1 and H9N2 Avian Influenza Viruses by inhibiting the production of type I interferons by Huizi Li, Shishi Wang, Ruihong Guo, Xijiao Chen, Yuanyuan Huang, Weixin Jia, Zhangyong Ning

“…Avian influenza viruses (AIVs) are potential pandemic of global concern, posing a major threat to both the poultry industry and human health. …”
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Sociodemographic and lifestyle predictors of incident hospital admissions with multimorbidity in a general population, 1999–2019: the EPIC-Norfolk cohort by Kay-Tee Khaw, Robert Luben, Shabina Hayat, Nicholas Wareham, Paul P Pharoah

“…Background The ageing population and prevalence of long-term disorders with multimorbidity are a major health challenge worldwide. The associations between comorbid conditions and mortality risk are well established; however, few prospective community-based studies have reported on prior risk factors for incident hospital admissions with multimorbidity. …”
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Trends in clinical encounters and management for infertility among women attending Australian general practice: a national longitudinal study using MedicineInsight, 2011 to 2021 by Alice R Rumbold, Michael Davies, Danielle Mazza, Jacqueline Boyle, Vivienne Moore, Renae C Fernandez, Luke E Grzeskowiak

“…Factors associated with increased likelihood of being provided infertility medications included younger age, holding a Commonwealth concession card (indicating low income), lower socioeconomic status and living outside a major city.Conclusions Clinical encounters related to infertility are increasing in primary care, with large variation evident in corresponding clinical management. …”
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Exploring the mediating role of blood metabolites in the relationship between gut microbiota and gastric cancer risk: a Mendelian randomization study by Xiaocheng Li, Xiaocheng Li, Huapeng Lin, Huapeng Lin, Huapeng Lin, Jing Peng, Jianping Gong

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Phenotypic Characterization and Antibiotic Resistance Patterns of Extended-Spectrum β-Lactamase- and AmpC β-Lactamase-Producing Gram-Negative Bacteria in a Referral Hospital, Saudi... by Mutasim E. Ibrahim, Mohammed Abbas, Abdullah M. Al-Shahrai, Bahaeldin K. Elamin

“…Emergence of pathogenic bacteria carrying β-lactamase-resistant determinants has become a major health problem in the hospital setting. The study aimed to determine antibiotic-resistant patterns and frequency of extended-spectrum β-lactamase- (ESBL-) producing Gram-negative bacteria (GNB) and AmpC β-lactamase-producing GNB. …”
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Hubungan antara Proteinuria dan Hipoalbuminemia pada Anak dengan Sindrom Nefrotik yang Dirawat di RSUP Dr. M. Djamil Padang periode 2009-2012 by Pratiwi Dian Pramana, Mayetti Mayetti, Husnil Kadri

“…<br />Kata kunci: Anak dengan sindrom nefrotik, Proteinuria, Hipoalbuminemia<br />Abstract<br />Nephrotic syndrome consist of massive proteinuria, hypoalbuminemia, edema, and may be accompanied by hypercholesterolemia. Proteinuria is a major symptom of nephrotic syndrome, while the other clinical symptoms considered secondary manifestations. …”
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The neighborhood walk: introducing first-year medical students to social determinants of health in underserved neighborhoods by Tien C. Nguyen, Lilly W. Tang, Emma Bryant, Awa S. Jobe, Amy J. Yu, Yui Sugiura, Thuy Bui

“…Similarly, 91.6% of students rated 4 or above when asked about knowledge of available resources in their neighborhood. The major learning outcomes from students were richness of community resources/history (35.7%), food insecurity (26.2%), and dissipation of previous stigma (23.8%). …”
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Blood Lead Levels among Blood Donors and High-Risk Occupational Groups in a Mining Area in Ghana: Implications for Blood Transfusion among Vulnerable Populations by Veronica Agyemang, Joseph K. Acquaye, Samuel B. E. Harrison, Felix B. Oppong, Stephany Gyaase, Kwaku P. Asante, Edeghonghon Olayemi

“…Lead poisoning has been a major global health problem for decades, and blood transfusion has been suspected as a neglected potential source of lead exposure. …”
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Factors associated with risk analysis for asymptomatic left ventricular diastolic dysfunction in nondialysis patients with chronic kidney disease by Yajuan Gao, Shengnan Chen, Jiani Fu, Cui Wang, Yali Tang, Yongbai Luo, Xiaozhen Zhuo, Xueying Chen, Yan Shen

“…Heart failure (HF) constitutes a major determinant of outcome in chronic kidney disease (CKD) patients. …”
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Mortality Predictors using Chest Computed Tomography Findings in COVID-19 Patients by Ali Yavuz Uzun, Yılmaz Üçüncü, Nur Hürsoy, Fatma Beyazal Çeliker, Zihni Yazıcı

“…Total lung volumes, diameters of major vascular structures, comorbidity status, and laboratory blood tests were measured or determined. …”
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