Gum Arabic (Acacia Senegal) Augmented Total Antioxidant Capacity and Reduced C-Reactive Protein among Haemodialysis Patients in Phase II Trial by Nour Elkhair Ali, Lamis AbdelGadir Kaddam, Suad Yousif Alkarib, Babikir Gabir Kaballo, Sami Ahmed Khalid, Abdalazim Higawee, Alaa AbdElhabib, Alaa AlaaAldeen, Aled O. Phillips, Amal Mahmoud Saeed

“…Oxidative stress (OS) is a risk factor of atherosclerosis and cardiovascular complications, which are major causes of mortality among ESRD patients. Haemodialysis (HD) is life-saving procedure, nevertheless it is an active chronic inflammatory status that could augment cardiovascular disease and increase mortality. …”
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Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO by Vidya Narayanaswami PhD, Kenneth Dahl PhD, Vadim Bernard-Gauthier PhD, Lee Josephson PhD, Paul Cumming PhD, Neil Vasdev PhD

“…On the other hand, chronic neuroglial activation is a major pathological mechanism in neurodegenerative diseases, likely contributing to neuronal dysfunction, injury, and disease progression. …”
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Probabilistic estimation of rheological properties in subduction zones using sequences of earthquakes and aseismic slip by Tobias Köhne, Rishav Mallick, Mark Simons

“…Abstract  Constraining the effective rheology of major faults contributes to improving our understanding of the physics of plate boundary deformation. …”
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Project ChemicalBlooms: Collaborating with citizen scientists to survey the chemical diversity and phylogenetic distribution of plant epicuticular wax blooms by Le Thanh Dien Nguyen, Nicole Groth, Kylie Mondloch, Edgar B. Cahoon, Keith Jones, Lucas Busta

“…Using gas chromatography–mass spectrometry, we found that the major wax classes reported from bulk wax mixtures can be present in wax bloom crystals, with fatty acids, fatty alcohols, and alkanes being present in many species' bloom crystals. …”
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Antibody response to Plasmodium vivax in the context of Epstein-Barr virus (EBV) co-infection: A 14-year follow-up study in the Amazon rainforest. by Luiz F F Guimarães, Bárbara A Rodrigues, Michelle H F Dias, Matheus G Barcelos, Maria F A Nascimento, Sâmick L Moreira-Nascimento, Sofia L Afonso, Barbara G S Abreu, Jaap M Middeldorp, Francis B Ntumngia, John H Adams, Camila Fabbri, Stefanie Lopes, Cor J F Fernandes, Flora S Kano, Luzia H Carvalho

“…The experimental approach focused on monitoring antibodies to the major blood-stage P. vivax vaccine candidate, the Duffy binding protein region II (DBPII-Sal1), including a novel engineered DBPII-based vaccine targeting conserved epitopes (DEKnull-2). …”
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The burden of non-specific chronic low back pain among adults in KwaZulu-Natal, South Africa: a protocol for a mixed-methods study by Morris Kahere, Themba Ginindza

“…Introduction Low back pain (LBP) is a major public health concern, affecting individuals of all age groups across the world. …”
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Exploring the Use of Activity Trackers to Support Physical Activity and Reduce Sedentary Behavior in Adults Diagnosed With Type 2 Diabetes: Qualitative Interview Study Using the RE... by William Hodgson, Alison Kirk, Marilyn Lennon, Xanne Janssen

“…Low levels of physical activity and sedentary behavior are major risk factors for developing the disease. Physical activity interventions incorporating activity trackers can reduce blood glucose levels in adults diagnosed with type 2 diabetes. …”
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Composition Characteristics and Potential Regions of PM2.5 during Winter Haze Pollution in Typical Industrial Areas, NW-China by Liyao Guo, Chao Gu, Kaiyuan Dong, Shengju Ou, Xueyan Zhao, Xinhua Wang, Zhensen Zheng, Wen Yang

“…The Positive Matrix Factorization (PMF) analysis shows that secondary particulate matter (47%), coal combustion (19%), fugitive dust (14%), industrial sources (10%) and vehicular emissions (10%) are identified as the major emission sources during winter in the K-D-W region. …”
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Effectiveness of implementation of sickle cell disease referral guidelines and other measures in paediatric department at a tertiary hospital in Saudi Arabia by Muhammad Matloob Alam, Abdulrhman Alathaibi, Hamdan Alghamdi, Jean Barrientos De Asis, Reynan Bautista, Mansour Aladwani, Mustafa Mohamed Selim

“…Finally, the number of wrong outpatient haematology visits decreased from 2 to 4 visits/week to 0 visits.Conclusions Staff education and adherence to guidelines are major priorities for the implementation of SCD referral guidelines in the paediatric department. …”
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Road Traffic Injuries and Related Safety Measures: A Multicentre Analysis at Military Hospitals in Tabuk, Saudi Arabia by Umar Yagoub, Nasrin S. Saiyed, Bahaa-eldin E. A. Rahim, Nizar Musawa, Attiya Mohammed Al Zahrani

“…Road traffic injuries are one of the major public safety issues around the world, as they put a great burden on countries’ economies. …”
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Evaluation of high-value bioproducts production by marine endophytic fungus Arthrinium sp. FAKSA 10 under solid state fermentation using agro-industrial wastes by Mohammad J. Alsarraf, Fuad Ameen, Abdullah Alfalih, Zirak Sajjad

“…This strain produced 46 metabolites with anticancer, antioxidant, antiviral, and cytotoxic properties, including major compounds like hexadecanoic acid methyl ester; hexadecanoic acid ethyl ester; 9, 12-octadecadienoic acid (Z, Z), methyl ester; 9-octadecenoic acid (Z)-, methyl ester, and 11, 14-eicosadienoic acid, methyl ester. …”
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ADAMTS1, CRABP1, and NR3C1 Identified as Epigenetically Deregulated Genes in Colorectal Tumorigenesis by Guro E. Lind, Kristine Kleivi, Gunn I. Meling, Manuel R. Teixeira, Espen Thiis-Evensen, Torleiv O. Rognum, Ragnhild A. Lothe

“…Background: Gene silencing through CpG island hypermethylation is a major mechanism in cancer development. In the present study, we aimed to identify and validate novel target genes inactivated through promoter hypermethylation in colorectal tumor development. …”
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Influence of food availability on the diet and activity budget of two western lowland gorilla (Gorilla gorilla gorilla) groups of differing size in the Dzanga-Ndoki National Park,... by Terence Fuh Neba, Giuseppe Donati, Angelique Todd, Shelly Masi

“…First, we compared food availability between home-ranges by monitoring leafing/fruiting patterns of major gorilla food trees. Second, we compared the groups’ activity budgets and diet composition/diversity, testing for differences between high (HF) and low fruit seasons (LF). …”
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Relationship between White Blood Count to Mean Platelet Volume Ratio and Clinical Outcomes and Severity of Coronary Artery Disease in Patients Undergoing Primary Percutaneous Coron... by Altekin Refik Emre, Kilinc Ali Yasar, Yanikoglu Atakan, Cicekcibasi Orhan, Kucuk Murathan

“…The endpoint of our study is major adverse cardiac events (MACEs) seen in the in-hospital and follow-up periods. …”
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Left ventricular hypertrophy in young hypertensives: the possible crosstalk of mTOR and angiotensin-II -a case-control study by Busayo Onafowoke Oguntola, Stephen Olawale Oguntola, Opeyemi Ezekiel Ojo, Pauleen Ayomide Ukpabio, Adams Olalekan Omoaghe, Kehinde Samuel Olaniyi

“…Abstract Background Hypertension is a major cause of cardiac dysfunction. The earliest manifestation is left ventricular remodeling/hypertrophy. …”
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Assessing type-2 diabetes risk based on the Indian diabetes risk score among adults aged 45 and above in India by Karthika Maniyara, Prakash Babu Kodali

“…About 41.2% had a high risk of diabetes. Among major Indian states, Kerala leads with 64.4% of its adults 45 years and above at high risk of diabetes. …”
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Unveiling the epidemiology and community perspectives on bovine brucellosis in North Shewa, Central Highlands of Ethiopia by Aweke Engdawork, Abdela Bulbula, Awoke Melak, Haileleul Negussie

“…Abstract Brucellosis is a bacterial disease of many domestic and wild animals with great economic and public health importance. Although it has a major constraint in dairy production, comprehensive information regarding the epidemiology of brucellosis in dairy herds is limited. …”
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Management of volume load for patients undergoing hemodialysis via WeChat and home monitoring in China: a protocol for a cluster-randomized trial by Xiaocui Wang, Bonan Yan, Shipeng Zhang, Yuanke Zhou, Qinxiu Zhang, Xueying Li

“…Abstract Background Volume overload is a major mortality risk in hemodialysis (HD) patients. …”
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Sex Disparity in Characteristics, Management, and In-Hospital Outcomes of Patients with ST-Segment Elevated Myocardial Infarction: Insights from Henan STEMI Registry by Shan Wang, You Zhang, Qianqian Cheng, Datun Qi, Xianpei Wang, Zhongyu Zhu, Muwei Li, Junhui Zhang, Dayi Hu, Chuanyu Gao, On behalf of Henan STEMI registry study group

“…Women experienced worse in-hospital outcomes, and age and cardiovascular risk factors were major factors influencing sex-related differences. …”
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Food purchase patterns, food policy recognition, and food environment satisfaction among adults in Jeju, Korea, according to food security: a cross-sectional study by Sumin Kim, Youjeong Jang, Hyunji Ham, Hanbin Ko, Insuk Chai, Kyungho Ha

“…Objectives Recently, food insecurity has been a major public health issue along with the food crisis caused by COVID-19, climate change, and the polarization of food supply due to socioeconomic disparities. …”
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