Proton pump inhibitors versus histamine-2 receptor antagonists for stress ulcer prophylaxis during extracorporeal membrane oxygenation: a propensity score-matched analysis by Hiroki Matsui, Hideo Yasunaga, Hiroshi Tanaka, Yutaka Kondo, Hiroyuki Ohbe, Kiyohide Fushimi

“…Purpose Patients receiving extracorporeal membrane oxygenation (ECMO) generally receive proton pump inhibitors (PPIs) or histamine-2 receptor antagonists (H2RAs) to avoid major gastrointestinal bleeding. Our aim was to compare outcomes between patients receiving PPIs and H2RAs for stress ulcer prophylaxis during ECMO.Materials and methods We performed a retrospective cohort study using the Japanese Diagnosis Procedure Combination Database, using data recorded from 1 July 2010 to 31 March 2017. …”
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Anxiety, Depression, and Their Related Factors Among Parents/Guardians of Students Affected by Nigerian University Staff Strikes by Patrick Ayi Ewah, Idoo Womboh, Peter Agba Awhen, Felicia Agbor-Obun Dan

“…Conclusion: The university staff strikes in Nigeria pose a major threat to the psychological health of students’ parents/guardians. …”
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Identification of individual-level clinical factors associated with increased risk of death during heatwaves: a time-stratified case-crossover study using national primary care rec... by Shakoor Hajat, Ross Thompson, Sari Kovats, Emer O’Connell, Helen Macintyre

“…Background Despite an increase in heat-related deaths occurring in England in recent years, one of the key recommended actions of identifying individuals at risk and deploying targeted interventions is not routinely undertaken. A major contributing factor to this is a lack of understanding of the individual-level risk factors that would support an evidence-based approach to targeted prevention.Objective To identify individual-level clinical risk factors for heat-related mortality in England by using primary care records and to estimate potential effect modification of a range of pre-existing conditions, clinical measurements and prescribed medications.Methods A time-stratified case-crossover analysis was undertaken of 37 individual-level clinical risk factors. …”
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Impact of Economic Agglomeration on Carbon Emission Intensity and Its Spatial Spillover Effect: A Case Study of Guangdong Province, China by Qian Xu, Junyi Li, Ziqing Lin, Shuhuang Wu, Ying Yang, Zhixin Lu, Yingjie Xu, Lisi Zha

“…Further, the economic agglomeration effects of Guangdong Province increased the carbon emission intensity of major cities and smaller neighboring cities. The stacking effect of economic agglomeration between cities also affected the carbon emission intensity of neighboring cities in the region. …”
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Barriers to nurse-led delirium management in intensive care units: an integrative systematic review using COM-B model by Mokhtar Abdu Almoliky, Sameer Alkubati, Khalil Saleh, Salman Alsaqri, Saddam A. Al-Ahdal, Galal Albani, Mujeeb A. Sultan

“…Motivation was represented by addressing delirium as a major problem, self-confidence, psychological support and considering nurse’s views. …”
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Genome-wide association studies identify two novel BMP15 mutations responsible for an atypical hyperprolificacy phenotype in sheep. by Julie Demars, Stéphane Fabre, Julien Sarry, Raffaella Rossetti, Hélène Gilbert, Luca Persani, Gwenola Tosser-Klopp, Philippe Mulsant, Zuzanna Nowak, Wioleta Drobik, Elzbieta Martyniuk, Loys Bodin

“…Some sheep breeds are naturally prolific, and they are very informative for the studies of reproductive genetics and physiology. Major genes increasing litter size (LS) and ovulation rate (OR) were suspected in the French Grivette and the Polish Olkuska sheep populations, respectively. …”
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Treatment and prescribing trends of antihypertensive drugs in 2.7 million UK primary care patients over 31 years: a population-based cohort study by Tibor Schuster, Laurent Azoulay, Julie Rouette, Emily G. McDonald, James M. Brophy

“…The prevalence of primary care patients with antihypertensive drug prescriptions increased from 7.8% (1988) to 21.9% (2018) and was observed for all major classes except thiazide diuretics. Patients with hypertension initiated thiazide diuretics (36.8%) and beta-blockers (23.6%) as first-line drugs before 2007, and ACE inhibitors (39.9%) and CCBs (31.8%) after 2007. …”
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A Study on Dust Storm Pollution and Source Identification in Northwestern China by Hongfei Meng, Feiteng Wang, Guangzu Bai, Huilin Li

“…In April 2023, a major dust storm event in Lanzhou attracted widespread attention. …”
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Comprehensive analysis of causal pathogens and determinants influencing black rot disease development in MD2 pineapples by Manori Kuruppu, Yasmeen Siddiqui, Hala Badr Khalil, Hala Badr Khalil

“…However, postharvest losses due to pathological diseases remain a challenge. Black rot, a major postharvest disease, causes significant economic losses in pineapples. …”
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Relationship between Tectonism and Composition and Pore Characteristics of Shale Reservoirs by Fuhua Shang, Yanming Zhu, Haitao Gao, Yang Wang, Ruiyin Liu

“…Tectonism is one of the major controlling factors of shale gas accumulation and enrichment in China. …”
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Corneal endothelial dysfunction: etiology, pathogenesis, and current treatment approaches by S.V. Trufanov, E.P. Salovarova

“…Bullous keratopathy is characterized by progressive corneal edema and occurs mainly in elderly population. The major goals of the treatment are to minimize persistent corneal edema and to improve associated discomfort and poor vision. …”
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Polypharmacy and anticholinergic burden scales in older adults: a cross-sectional study among psychiatric outpatients in a tertiary care hospital by Manjunath Bidarolli, Biswadeep Das, Vikram Singh Rawat, Sachin Manocha, Hannah Theresa Sony, Akash Agnihotri, Mahima Gupta, Franklin Agera

“…Polypharmacy, common in this population, is a major contributor to anticholinergic burden, which is linked to cognitive and physical decline. …”
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Predicting academic procrastination of students based on academic self-efficacy and emotional regulation difficulties by Hamidreza Farhadi Rad, Shima Bordbar, Jamshid Bahmaei, Marjan Vejdani, Ali Reza Yusefi

“…Abstract Academic procrastination is one of the major factors that can be a serious obstacle for students to achieve academic progress and success. …”
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Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial by Judith Bellapart, Vinesh Appadurai, Melissa Lassig-Smith, Janine Stuart, Christopher Zappala, Rob Boots

“…Melatonin has been proposed as a pharmacological strategy to improve sleep, but studies have shown that the increase in plasma levels of melatonin do not correlate to a beneficial clinical effect; in addition, melatonin’s short half-life may be a major limitation to achieving therapeutic levels. …”
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Effect of COVID-19 on Severity of Signs and Symptoms of Autoimmune Diseases by Ramand Mohammed Haji, Nabaz Ali Ahmed, Shakhawan Azad Ahmed

“…Rheumatoid arthritis was a major type 16 (48.5%) of the autoimmune disease compared to other types, Ankylosing Spondylitis 8(24.2%) cases, and Ulcerative Colitis 6(18.2%) cases respectively while Crohn's disease was the minimum 3(9.1%) cases and before the got COVID-19 most of the cases 25(75.8%) had moderate intensity signs and symptoms of their autoimmune diseases and 8(24.2%) cases had severe signs and symptoms but after they recovered from the COVID-19 disease the rate of their signs and symptoms changed to mild 19(57.6%) and moderate 14(42.4%) intensity while severe intensity signs and symptoms were zero with highly significant differences (P-value 0.0001). …”
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The association of BMI and subclinical myocardial dysfunction in breast cancer patients after single or dual anti-HER2 targeted therapy by Feng Zhang, Siyuan Wang, Chao Yu, Wenying Jin, Dan He, Xiaoxiao Hu, Shu Wang, Tiangang Zhu

“…Weight reduction should be the major measure to prevent subclinical myocardial dysfunction for these patients.…”
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Aspectos de la gramatización antigua de la lengua vasca by Aurélie Arcocha-Scarcia, Joseba Andoni Lakarra

“…In §4 we include the principal conclusions, among which that publications in the vernacular language needed the establishment of linguistic tools, the development of grammatization and a cultural context that permitted the “enlightening” of the language; for that reason, both the LVP and the NT and the RS were born within a continuum, not ex-nihilo or on an island, which makes it essential to reread these works in relation to the printing workshops, scrutinising their ideological surroundings in the context of the extension of new ideas, in an interconnected geopolitical space which experienced major jumps and evolutions in this period. The cited bibliography is included in §5.…”
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Assessment of Traffic-Related Ambient Air Particulate Matter (PM) Levels in Douala, Cameroon by Yannick Cédric Ngangmo, Cyrille Adiang Mezoue, Cyrille Meukaleuni, Brice B. S. Wandjie, David Monkam

“…In addition, it provides essential information on the pollution in Douala, which can be a major source of illness in the city and must be addressed.…”
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Fluid volume status detection model for patients with heart failure based on machine learning methods by Haozhe Huang, Jing Guan, Chao Feng, Jinping Feng, Ying Ao, Chen Lu

“…Backgroud: Fluid volume abnormalities are a major cause of exacerbations in heart failure patients. …”
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Prevalence of neonatal sepsis and associated factors among neonates admitted in the neonatal intensive care unit at Lira Regional Referral Hospital, Northern Uganda. by Brendah Katugume, JohnBaptist Muzungu, Nelson Okello, Eustes Kigongo, Deborah Andrinar Namutebi

“…Further research will be conducted on the major causative agents and outcomes of NS in the NICU of LRRH.…”
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