A Small Increase in Serum Creatinine within 48 h of Hospital Admission Is an Independent Predictor of In-Hospital Adverse Outcomes in Patients with ST-Segment Elevation Myocardial... by Jiajia Zhu, Wenxian Liu, Jiang Li, Changsheng Ma, Dong Zhao

“…The primary outcome was the incidence of major adverse cardiovascular events (MACE). Secondary outcomes included the incidence of massive hemorrhage, in-hospital death, atrial fibrillation, heart failure, cardiogenic shock, cardiac arrest, and stroke. …”
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COVID-19's impact on hospital stays, mortality, and readmissions for poverty-related diseases, noncommunicable diseases, and injury groups in Thailand. by Satiti Palupi, Kyaw Ko Ko Htet, Vorthunju Nakhonsri, Chumpol Ngamphiw, Peerapat Khunkham, Sanya Vasoppakarn, Narumol Atthakul, Sissades Tongsima, Chantisa Keeratipusana, Watcharapot Janpoung, Virasakdi Chongsuvivatwong

“…We categorized WHO's three disease groups: poverty-related, noncommunicable, and injury groups using the International Classification of Diseases (ICD)-10 of initial admission of patients, and we analyzed three major outcomes: prolonged (≥ 90th percentile) length of stay (LOS), hospital mortality, and readmission pre-, during, and post-COVID-19 pandemic peak. …”
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Prevalence of Intestinal Parasites and Gastrointestinal Carriage of Pathogenic Gram Negative Enteric Bacteria among Apparently Healthy Food Handlers of Public Hospitals, Addis Abab... by Tegegn Belhu, Kinfe Fissehatsion, Abraham Tesfaye, Dr Yohannes Woldekidan, Kassu Desta

“…Foodborne diseases are major public health problems in developing countries like Ethiopia. …”
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Home Healthcare Medication Safety risks among older adults with chronic diseases: a qualitative study by Tahereh Najafi Ghezeljeh, Zahra Amrollah Majdabadi Kohne, Mansoureh Ashghali Farahani, Forough Rafii, Sahar Keyvanloo Shahrestanaki

“…Findings Factors associated with medication safety risks were found to rely on its major components Patients’ attribution, Families’ characteristics, Home care centers’ condition, Health caregivers’ characteristics, and the Homes’ situations, where these factors all account for various medication safety risks. …”
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Smoking as a risk factor for lung cancer in women and men: a systematic review and meta-analysis by Sanne A E Peters, Mark Woodward, Paul Mitchell, Rachel R Huxley, Gemma Taylor, Linda M O’Keeffe

“…The pooled ratio of the RRs was 0.92 (95% CI 0.72 to 1.16; I2=89%; p<0.001), with no evidence of publication bias or differences across major pre-defined participant and study subtypes. …”
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Prevalence, Antimicrobial Resistance, and Associated Factors of Streptococcus pneumoniae Colonization Rate among Old-Age Patients with Respiratory Tract Infection Attending Sheik H... by Surafel Mekuria, Ayichew Seyoum, Zerihun Ataro, Tigist Abebe, Kedir Urgessa

“…Colonization of the upper respiratory tract (carriage of pneumococcus) by S. pneumoniae is considered a prerequisite for pneumococcal infection. It is the major cause of respiratory tract infection and frequent cause of physician visits, hospitalization, and death among old-aged patients because of their low immunity status. …”
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Assessing feasibility and acceptability of increasing access to sexual and reproductive health and rights through pharmacy outlets and community health volunteers: lessons from pil... by Wilson Liambila, Francis Obare, Saumya RamaRao, Monica Oguttu, Carol Nyandat, Benedict Denga, Zeka Wekesa

“…Abstract Background Both unintended pregnancy and unsafe abortion are major public health problems in Kenya. The World Health Organization recommends the use of medication abortion to stop unwanted pregnancies. …”
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Interaction of the Wolbachia surface protein with a novel pro-viral protein from Aedes aegypti by Mazhar Hussain, Zhi Qi, Sassan Asgari

“…For this, we embarked on identifying the interacting proteins with a major Wolbachia protein, WSP, which is both structural and also secreted into the host cells. …”
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Ten-year trends in clinical characteristics and outcome of children hospitalized with severe wasting or nutritional edema in Malawi (2011-2021): Declining admissions but worsened c... by Mphatso Nancy Chisala, Celine Bourdon, Emmanuel Chimwezi, Allison I Daniel, Chikondi Makwinja, Dominic Wang, Linnea Weise, Isabel Potani, Emmie Mbale, Robert J H Bandsma, Wieger P Voskuijl

“…Longitudinal data from major NRUs can identify shifts in clinical profiles or outcomes, and this information can be leveraged to promote earlier care-seeking, improved risk stratification, and implementation of more patient-centered treatments.…”
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Does the transition from face-to-face to face-to-screen improve oral health literacy? A non-inferiority randomized controlled trial by Negar Ebrahimi, Katayoun Sargeran, Reza Yazdani, Ahmad Reza Shamshiri

“…Oral health literacy (OHL) plays a major role in reducing oral health inequalities. …”
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Elevated Plasma Soluble Triggering Receptor Expressed on Myeloid Cells-1 Level in Patients with Acute Coronary Syndrome (ACS): A Biomarker of Disease Severity and Outcome by Shachaf Shiber, Vitaly Kliminski, Katia Orvin, Iftach Sagy, Mordehay Vaturi, Ran Kornowski, Michael Drescher, Yair Molad

“…Secondary endpoints were the association of plasma levels of sTREM-1 with day 30 and month 6 major adverse cardiovascular events (MACE) defined as death, ACS, stroke, and need for coronary revascularization, as well as with CAD severity. …”
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Differential effects of clary sage (Salvia sclarea L.) oil and linalyl acetate on depression levels in diabetic foot ulcer patients with T2DM: a randomized blinded controlled trial by Ji Won Son, Purum Kang, Sun Seek Min, Geun Hee Seol, Geun Hee Seol

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Application of 3D Printing Technology in the Mechanical Testing of Complex Structural Rock Masses by Yingjie Xia, Qingkun Meng, Chuanqing Zhang, Ning Liu, Zhenxing Zhao, Jun Chen, Gao Yang

“…In this study, through a comprehensive review of the technical progress, equipment situation, application fields, and challenges of the use of 3DP technology, the following conclusions were obtained: (1) 3DP technology has advantages over traditional rock mass specimen preparation techniques, and the verification of test results using 3D printed samples shows that the 3DP has broad application prospects in geotechnical engineering. (2) The combination of 3DP and other advanced techniques can be used to achieve the accurate reconstruction of complex structural rock masses and to obtain the mechanical and failure characteristics of the same rock mass structure under different mechanical boundary conditions. (3) The development of 3DP materials with high strength, high brittleness, and low ductility has become the major bottleneck in the application of 3DP in geotechnical engineering. (4) 3D printers need to meet the high precision and large size requirements while also having high strength and long-term printing ability. …”
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Empowering access: unveiling an overall composite spatial accessibility index to healthcare services in Southeastern Iran by Ahmad Raeesi, Soheil Hashtarkhani, Mahmood Tara, Narjes Sargolzaei, Behzad Kiani

“…Furthermore, this study provides evidence of major shortfalls in healthcare access across Sistan and Baluchestan Province. …”
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Ezetimibe Improves Rosuvastatin Effects on Inflammation and Vascular Endothelial Function in Acute Coronary Syndrome Patients Undergoing PCI by Changqing Sun, Wuyang Zheng, Ling Liang, Zuheng Liu, Wenchao Sun, Rong Tang

“…Patients in the combination versus rosuvastatin group appeared to suffer from less major adverse events. Periprocedural therapy of ezetimibe improves rosuvastatin effects on proinflammatory responses and endothelial function associated with ACS patients undergoing PCI. …”
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Understanding Individual Differences in Happiness Sources and Implications for Health Technology Design: Exploratory Analysis of an Open Dataset by Edel Ennis, Raymond Bond, Maurice Mulvenna, Colm Sweeney

“…However, as with many constructs, the unique ways in which individuals experience happiness present major challenges for designing personalized DMHIs. …”
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TIESA IR TIKRUMAS WITTGENSTEINO FILOSOFIJOJE by Albinas Plėšnys

“…The conception of truth here turns into a basis of distinguishing between what can be talked about and what should be passed over in silence. Truth is one of the major problems in Tractatus. The later Wittgenstein abandoned his ontological scheme and a related conception of exact truth. …”
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Les changements hydromorphologiques de l’estuaire de la Loire et l’évolution du port de Rezé/Ratiatum (Loire-Atlantique) by Rémy Arthuis

“…In 2005, when a major research programme was initiated with the aim of investigating the ancient district of Saint-Lupien and its supposed port, little was known about the Loire river landscapes and the dynamics of the river during Antiquity was in its infancy. …”
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F-box protein Fbx23 acts as a transcriptional coactivator to recognize and activate transcription factor Ace1. by Zhongjiao Liu, Kexuan Ma, Panpan Zhang, Siqi Zhang, Xin Song, Yuqi Qin

“…The limited number of identified ubiquitin ligase-substrate pairs is a major bottleneck in the ubiquitination field. Penicillium oxalicum contains many transcription factors, such as BrlA, CreA, XlnR, and Ace1, conserved in filamentous fungi that regulate the fungal development and transcription of (hemi)cellulase genes. …”
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Effectiveness of the voluntary disclosure of corporate information and its commitment to climate change by F.G. Arredondo Trapero, E.M. Guerra Leal, J. Kim

“…This study investigated the effectiveness of companies in Climate Action and tested its impact on greenhouse gas emissions at the country and per capita levels.METHODS: This study focuses on companies of the countries from the main Latin American economies (Mexico, Chile, Brazil, Colombia, and Argentina) and their major trading partners (the United States of America, Canada, China, Korea, Germany, and Japan). …”
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