Clinical characteristics and treatment outcomes of patients with insulinoma–a single center's experience of 76 cases over a 10-year period by Wei Li, Yali Cheng, Qingyong Ma, Zheng Wu, Zheng Wang

“…The incidence of pancreatic fistula, bleeding and major complications after the operation of pancreatic head/neck insulinoma was higher than that of pancreatic body/tail insulinoma. …”
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Incidence and Factors Associated with Postoperative Delayed Hyponatremia after Transsphenoidal Pituitary Surgery: A Meta-Analysis and Systematic Review by Cheng-Chi Lee, Yu-Chi Wang, Yu-Tse Liu, Yin-Cheng Huang, Peng-Wei Hsu, Kuo-Chen Wei, Ko-Ting Chen, Ya-Jui Lin, Chi-Cheng Chuang

“…This meta-analysis and systematic review evaluated the incidence of postoperative delayed hyponatremia and found it as a major cause of unplanned readmissions after transsphenoidal pituitary surgery. …”
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Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1β,... by André L. F. Sampaio, Jesmond Dalli, Vincenzo Brancaleone, Fulvio D'Acquisto, Mauro Perretti, Carmen Wheatley

“…In resolution, 24 h after LPS, HOCbl completely abrogates a major late mediator of sepsis mortality, high mobility group box 1 (HMGB1) mRNA, inhibits iNOS mRNA, and attenuates LPS-induced hepatic inhibition of eNOS mRNA, whilst showing increased, but still moderate, NOS activity, relative to LPS only. experiments (LPS+D-Galactosamine) HOCbl afforded significant, dose-dependent protection in mice Conclusions. …”
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Multiomics profiling reveals the benefits of gamma-delta (γδ) T lymphocytes for improving the tumor microenvironment, immunotherapy efficacy and prognosis in cervical cancer by Xiaofeng Wang, Chen Li, Jie Chen, Zhiqiang Wu, Zhen Zhang, Junyi Li, Lu Yu, Yong Guan, Yuhan Zhang, Yuanjie Cao, Yancheng Liu, Hui Bai, Shaochuan Liu, Miaomiao Gao, Chenglu Lu, Zhen Tao, Zhiyong Yuan

“…Background As an unconventional subpopulation of T lymphocytes, γδ T cells can recognize antigens independently of major histocompatibility complex restrictions. Recent studies have indicated that γδ T cells play contrasting roles in tumor microenvironments—promoting tumor progression in some cancers (eg, gallbladder and leukemia) while suppressing it in others (eg, lung and gastric). γδ T cells are mainly enriched in peripheral mucosal tissues. …”
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Mineralogy and geochemistry of shale from Shanxi Formation, Southern North China Basin: Implication for organic matter accumulation by Qian Chen, Pei Li, Xiaoliang Wei, Changsheng Chen, Wei Dang, Haikuan Nie, Jinchuan Zhang

“…Based on lithologic observations, mineral and major elemental analyses of the Shanxi Sahle in the Southern North China Basin (SNCB), we conducted a preliminary investigation into the depositional environment, climate, and factors controlling the organic matter (OM) accumulation. …”
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Using stated-preferences methods to develop a summary metric to determine successful treatment of children with a surgical condition: a study protocol by Nigel Hall, Marian Knight, Nick Lansdale, Lisa Hinton, Charles Opondo, Simon Kenny, Stefano Giuliani, John Buckell, Oliver Rivero-Arias, Kokila Lakhoo, Alexander Macdonald, Crispin Jenkinson, Benjamin Allin, Rema Ramakrishnan, Gregor Walker, Timothy Bradnock, Karolina Kuberska, Benjamin M Craig, Goher Ayman, Anna May Long, Joanne Shepherd

“…Consequently, it is important to reduce unwarranted variation. However, major barriers to this are the inability to detect differences between observed and expected hospital outcomes based on the casemix of the children they have treated, and the inability to detect variation in significant outcomes between hospitals. …”
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Use of Pre- and Intensified Postprocedural Physiotherapy in Patients with Symptomatic Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement Study (the 4P-TAVR Study) by M. Weber, U. Klein, A. Weigert, W. Schiller, V. Bayley-Ezziddin, D. C. Wirtz, A. Welz, N. Werner, E. Grube, G. Nickenig, J.-M. Sinning, A. Ghanem

“…Physiotherapy prior to open-heart surgery lowers the rate of pneumonia and length of the hospital stay. Pneumonia is a major contributor to short-term mortality following transcatheter aortic valve replacement (TAVR). …”
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The Rise of SARS-CoV-2 Variants and the Role of Convalescent Plasma Therapy for Management of Infections by Mohamed, Moubarak, Keneth Iceland, Kasozi, Helal F., Hetta, Hazem M., Shaheen, Abdur, Rauf, Hayder M., Al-kuraishy, Safaa, Qusti, Eida M., Alshammari, Emmanuel Tiyo, Ayikobua, Fred, Ssempijja, Adam Moyosore, Afodun, Ritah, Kenganzi, Ibe Michael, Usman, Juma John, Ochieng, Lawrence Obado, Osuwat, Kevin, Matama, Ali I., Al-Gareeb, Emmanuel, Kairania, Monica, Musenero, Susan, Christina Welburn, Gaber, El-Saber Batiha

“…The emergence of more virulent variants of SARS-Cov-2 remains challenging for effective disease control during this pandemic. Major variants identified to date include B.1.1.7, B.1.351; P.1; B.1.617.2; B.1.427; P.2; P.3; B.1.525; and C.37. …”
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Examining the impact of implementing routine rotavirus vaccination on the number of paediatric admissions due to diarrhoea and dehydration in Kenyan hospitals: A study using interr... by Samuel Akech, Lucas Malla, Daisy Chelangat, Reuben C. Langat

“…Background Dehydration secondary to diarrhoea is a major cause of hospitalization and mortality in children aged less than five years. …”
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Ethical issues in the development and implementation of nutrition-related public health policies and interventions: A scoping review. by Thierry Hurlimann, Juan Pablo Peña-Rosas, Abha Saxena, Gerardo Zamora, Béatrice Godard

“…<h4>Background</h4>The limited integration of ethics in nutrition-related public health policies and interventions is one major concern for those who have the task of implementing them. …”
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Ophiostomatoid fungi associated with pine bark beetles and infested pines in south-eastern Australia, including Graphilbum ipis-grandicollis sp. nov. by Conrad Trollip, Angus J. Carnegie, Quang Dinh, Jatinder Kaur, David Smith, Ross Mann, Brendan Rodoni, Jacqueline Edwards

“…To achieve this, we reviewed Australian plant pathogen reference collections, and analysed samples collected during forest health surveillance programs from the major pine growing regions in south-eastern Australia. …”
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Knowledge, Attitude, and Preventive Practices towards Sexually Transmitted Infections among Preparatory School Students in West Gojjam Zone, Ethiopia by Ayalnesh Asmamaw Kassie, Temesgen Worku Gudayu, Bilen Mekonnen Araya

“…Sexually transmitted infections are major public health concerns that mostly affect adolescents and young people. …”
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Robotic-assisted left thoracic small-incision minimally invasive coronary artery bypass grafting: a case series report by HE Peiling, SONG Yi, YUAN Ye

“…No mortality was observed during or within 30 d of hospitalization， and 1 patient was readmitted due to pericardial effusion within 30 d， and was discharged after symptomatic treatment including pericardiocentesis and drainage. No deaths， major adverse cardiovascular and cerebrovascular events （MACCE）， or re-revascularization occurred in all patients during outpatient and telephone follow-up. …”
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Translation and psychometric evaluation of the Danish version of the knee outcome survey - activities of daily living scale in patients with anterior cruciate ligament injuries by Kamilla Arp, Claus Varnum, Ulrik Dalgas, Bettina Mølri Knudsen, Signe Timm, Bjarke Viberg, Kim Gordon Ingwersen

“…Structural validity (factor analysis), Internal consistency (Cronbach`s alpha), construct validity (hypothesis testing), test-retest reliability (Intraclass Correlation Coefficient [ICC]), test-retest agreement (Bland-Altman plots with 95% Limits of Agreement), Standard Error of Measurement (SEM), Smallest Detectable Chance (SDC), responsiveness (construct approach with hypothesis testing) and floor/ceiling effects were assessed. Results No major problems were revealed in the cross-cultural adaptation process. …”
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Pharmacists' knowledge, attitudes, and perceived barriers to cancer pain management: a cross-sectional survey in Chongqing, China by Yu Liu, Tao Chen, Xinyu Li, Jie Song, Fujun Zhang

“…This study assessed pharmacists' attitudes and competencies in cancer pain management, identified major barriers in China, and provided evidence for the development of targeted interventions. …”
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A Longitudinal Study on Campylobacter spp. in an Integrated Broiler Complex in the Southeast Region of the United States: Prevalence and Phylogenetic Analysis by Yagya Adhikari, Matthew A. Bailey, Dianna V. Bourassa, Sabin Poudel, Richard J. Buhr, Kenneth S. Macklin

“…Poultry meat products are considered the major contributors to Campylobacteriosis in humans. …”
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Chromosomal analysis and short-term outcome of prenatally diagnosed congenital heart disease by Marcellino Verbeke, Laurens Hannes, Koen Devriendt, Kris Van den Bogaert, Bjorn Cools, Luc De Catte, Marc Gewillig, Jeroen Breckpot

“…In addition, postnatal mortality both before the age of 1 month or before the age of 1 year was significantly associated with lower postmenstrual age at birth, CHD severity score B and major ECA at birth. These results underscore the importance of genotyping and of accurate cardiac and extracardiac phenotyping for prognostication in fetuses with CHD.…”
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Relationship between multiple morbidities and performance on the Timed Up and Go test in elderly patients: a cross-sectional study by Arsalan Tariq, Sayed Alireza Mousavi Zadeh, Muhammad Ammar, Nafisehsadat Mousavizadeh, Arash Hajary, Somayeh Mohamadi

“…Objective To investigate how various morbidities affect older patients’ performance on the Timed Up and Go (TUG) test.Design Cross-sectional study.Setting The seven government hospitals of Lahore, Pakistan, included are major tertiary care centres, representing an older patient population of Punjab, Pakistan.Method 160 elderly participants completed the TUG test, frailty evaluations and Charlson Comorbidity Index (CCI) scoring to assess mobility, frailty and comorbidity burden. …”
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Retrospective evaluation of multiplex PCR panel results from CSF samples in a university hospital by Funda Şahin, Nida Özcan, Erdal Özbek, Selahattin Atmaca, Hakan Temiz

“… Aim: Given the significant mortality and sequelae due to meningitis, rapid diagnosis and initiation of treatment have a major impact on patient outcomes. In many cases of meningitis/meningoencephalitis, empirical treatment should be initiated immediately. …”
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Association of abstinence time with semen quality in men who undergoing fertility evaluation: a cross-sectional study from 3052 participants by Guanying Yao, Qinglin Qi, Xianchao Dou, Wen Zhou, Shun Bai, Xi Zhang, Xi Zhang

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