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18921
RETRACTED: The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model
Published 2022-04-01“…Vag8 further increased bradykinin levels by inhibiting the C1 esterase inhibitor, the major downregulator of the contact system, which generates bradykinin. …”
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18922
Platelet-Rich Plasma Improves the Wound Healing Potential of Mesenchymal Stem Cells through Paracrine and Metabolism Alterations
Published 2019-01-01“…Chronic and acute nonhealing wounds represent a major public health problem, and replacement of cutaneous lesions by the newly regenerated skin is challenging. …”
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18923
Characterisation of the effects of the chemotherapeutic agent paclitaxel on neuropathic pain-related behaviour, anxiodepressive behaviour, cognition, and the endocannabinoid system...
Published 2025-01-01“…Paclitaxel (PTX) is a commonly used chemotherapeutic drug, however, one of its major adverse effects is chronic neuropathic pain, with the incidence being higher in women than in men. …”
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18924
An algorithm for infectious screening of corneal donors in eye tissue bank of the Fyodorov Eye Microsurgery Federal State Institution
Published 2022-07-01“…Overall, the positive serology and hemolysis were the major contraindications and led to exclusion 33.4% (n=1162) of incoming corneas in the ETB. …”
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18925
Human Action Recognition Using Difference of Gaussian and Difference of Wavelet
Published 2023-09-01“…Human Action Recognition (HAR) attempts to recognize the human action from images and videos. The major challenge in HAR is the design of an action descriptor that makes the HAR system robust for different environments. …”
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18926
Evaluation of the Antioxidant and Cytotoxic Activities on Cancer Cell Line of Extracts of Parasitic Plants Harvested in Tunisia
Published 2020-06-01“…The highest total phenolic content was determined in O. crenata acetone extract (3.53±0.20 mmol GAE/g) and in O. lavandulacea methanol extract (2.29±0.02 mmol GAE/g). 1 H NMR spectroscopy revealed the presence of amino acids, organic acids and carbohydrates. The major fatty acids in the oils were 18:2 n -6, 16:0, 18:1 n -9, and 18:3 n -3. …”
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18927
Inflamed immune phenotype predicts favorable clinical outcomes of immune checkpoint inhibitor therapy across multiple cancer types
Published 2024-02-01“…On subgroup analysis, the IIP was generally prognostic of favorable PFS across major patient subgroups, with the exception of the microsatellite unstable/mismatch repair deficient subgroup.Conclusion The AI-based IIP may represent a practical, affordable, clinically actionable, and tumor-agnostic biomarker prognostic of ICI therapy response across diverse tumor types.…”
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18928
Impact of distress and anxiety due to COVID-19 on digital addictions in university students in the third wave period [version 2; peer review: 3 approved]
Published 2025-01-01“…Abstract Background Digital addictions are a major problem worldwide, which has increased considerably during the COVID-19 pandemic. …”
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18929
TGR5 receptors in SF1-expressing neurons of the ventromedial hypothalamus regulate glucose homeostasis
Published 2025-01-01“…Results: Our findings reveal that TGR5 in SF1 neurons does not play a major role in the regulation of food intake or body weight under standard chow, but it is involved in the adaptive feeding response to the acute exposure to cold or to a hypercaloric, high-fat diet, without changes in energy expenditure. …”
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18930
Did the resurgence of childhood lower respiratory infections offset the initial benefit of COVID-19-related non-pharmaceutical interventions in children? A time-series analysis
Published 2025-02-01“…Abstract Background Following non-pharmaceutical interventions (NPI) lifting in 2021, an important surge in childhood lower respiratory tract infections (LRTI) was reported in several countries, raising major concerns about the middle-term consequences of such interventions. …”
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18931
Detection of antimicrobial resistance in Glaesserella parasuis in South China using whole-genome sequencing
Published 2025-01-01“…IntroductionGlaesserella parasuis causes Glässer’s disease in pigs, a leading cause of death in swine herds and a major contributor to economic losses in the global swine industry. …”
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18932
The importance of stem cells in the treatment of type 1 diabetes, type 2 diabetes and diabetes complications
Published 2025-01-01“…For type 1 diabetes, MSCs reduced inflammation, preserved pancreatic islet function, and decreased insulin requirements without major adverse effects. Pluripotent stem cells showed promise in islet transplantation, achieving stable glycemic control in clinical trials. …”
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18933
Morphological, Physiological, and Molecular Responses to Heat Stress in Brassicaceae
Published 2025-01-01“…Given the rising global temperatures, heat stress has become a major abiotic challenge, affecting the growth and development of various crops and significantly reducing productivity. …”
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18934
Single-cell sequencing reveals cell heterogeneity and aberrantly activated pathways associated with microvascular invasion in hepatocellular carcinoma
Published 2025-01-01“…IntroductionHepatocellular carcinoma (HCC) is the most common primary liver cancer, with microvascular invasion (MVI) identified as a major predictor of early recurrence. However, the intratumor cellular heterogeneity of MVI, the identification of pertinent biomarkers, and the role of intercellular signalling interactions in MVI progression are unclear. …”
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18935
Radiofrequency ablation vs. cryoablation for pediatric atrioventricular nodal reentrant tachycardia in the era of three-dimensional electroanatomical mapping
Published 2025-01-01“…Recurrence rates were 2.9% in the RF group and 0% in the Cryo group (p > 0.99), with no difference in AVNRT-free survival. No major complications, such as permanent atrioventricular (AV) block, were observed. …”
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18936
Nutrient Formulation—A Sustainable Approach to Combat PRSV and Enhance Productivity in Papaya
Published 2025-01-01“…Papaya Ring Spot Virus (PRSV) is a major threat to papaya production, which causes severe yield loss and reduces fruit quality. …”
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18937
Functional Tests and Surveys Used to Assess Nervous System Dysfunction in Patients with Fabry Disease – A Review
Published 2025-01-01“…These results challenge the widely accepted notion that autonomic neuropathy is a major contributor to Fabry disease symptoms and emphasize the need for further research into the specific mechanisms underlying the disease's clinical manifestations. …”
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18938
3D modeling to predict vascular involvement in resectable pancreatic adenocarcinoma
Published 2025-01-01“…Background: Current management of patients with borderline resectable pancreatic adenocarcinoma (BR-PDAC) depends on the degree of involvement of the major arterial and venous structures. The aim of this study was to evaluate 3D segmentation and printing to predict tumor size and vascular involvement of BR-PDAC to improve pre-operative planning of vascular resection and better select patients for neoadjuvant therapy. …”
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18939
Creation of new anastomosis for management of obstructive symptoms related to gastrojejunal anastomosis in patients who undergo gastric bypass: a case series
Published 2025-01-01“…EUS-guided anastomosis between the gastric pouch and Roux limb was created successfully in all patients, with no major adverse events. One patient experienced LAMS migration after 54 days. …”
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18940
Prognostic value of remnant-like particle cholesterol in ischemic heart failure patients following percutaneous coronary intervention
Published 2025-12-01“…The primary outcome was major adverse cardiovascular events (MACE). Kaplan-Meier survival analysis was used to assess the incidence of MACE and other outcomes. …”
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