The dipeptide carnosine alleviates acute pancreatitis in an experimental model by Heresh Rezaei, Saeed Heidari, Mohammad Mehdi Ommati, Babak Taheri, Forouzan Khodaei, Mohammad Ali Dehghani, Ayeh Rowhanirad, Azadeh Veisi-Goshtasb, Zahra Honarpishefard, Negar Azarpira, Hossein Niknahad, Reza Heidari

“…A significant increase in the pancreatic level of pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) was also evident in the l-arginine-treated mice (P<0.001). The major pancreatic tissue histopathological changes in the current AP model were the infiltration of inflammatory cells to the pancreas tissue, fluid accumulation, and acinar cell vacuolization/necrosis (P<0.05). …”
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Ventricular assist device implantation in children with a mechanical valve: An ACTION registry analysis by Sabena F. Hussain, MD, MSc, Elyse Miller, MD, Othman Aljohani, MBBS, MPH, Scott Auerbach, MD, David Bearl, MD, Victor Benvenuto, MD, Erica Bonura, MD, Richard L. Crawford, Anna Joong, MD, Jameson Dyal, MD, Christina Hartje-Dunn, MD, Sujit Jana, MD, Sonia Kaushal, MD, Melanie Lynn, MD, Joseph Spinner, MD, Laura Radel, MD, Alexander Raskin, MD, Diana Torpoco-Rivera, MD, Sarah J. Wilkens, MD, MPH, Chet R. Villa, MD

“…Patients with mechV had higher frequency of hemorrhagic stroke (18% vs 4.7%, p = 0.01) and major bleeding (44% vs 26%, p = 0.04). Conclusions: Patients with CHD with a mechV have similar survival to patients with non-mechV; however, there is higher risk of bleeding including hemorrhagic stroke.…”
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Genome-wide analysis of sugar transporter gene family in Erianthus rufipilus and Saccharum officinarum, expression profiling and identification of transcription factors by Sehrish Akbar, Xuiting Hua, Yingying Zhang, Gang Liu, Tianyou Wang, Huihong Shi, Zhen Li, Yiying Qi, Habiba Habiba, Wei Yao, Mu-Qing Zhang, Jisen Zhang

“…These STs belong to the Major Facilitator Superfamily (MFS), the largest family of STs in plants. …”
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Emerging Trends and New Developments in Transient Elastography: A Bibliometric and Cocitation Analysis from 1999 to 2017 by Jingjing Gu, Weimian Wang, Ziyuan Zou, Fangze Huang, Chihua Fang, Xun Li, Xiaolong Qi

“…The most productive journal was Journal of Hepatology (n=20). The major article type was original research article. …”
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The symbiont Wolbachia increases resistance to bifenthrin in Ectropis grisescens by regulating the host detoxification function by Tian Gao, Yong Zhang, Wanpeng Sun, Qiangkun Li, Xueyu Huang, Dian Zhi, Huabin Zi, Ruijie Ji, Yanhua Long, Chunmei Gong, Yunqiu Yang

“…The global issue of insecticide resistance among pests is a major concern. Ectropis grisescens Warren (Lepidoptera: Geometridae), is a highly destructive leaf-eating pest distributed in tea plantations throughout China and Japan, and has exhibited resistance to various insecticides. …”
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The Aryl Hydrocarbon Receptor (AhR) Is a Novel Gene Involved in Proper Physiological Functions of Pancreatic β-Cells by Shuhd Bin Eshaq, Jalal Taneera, Shabana Anjum, Abdul Khader Mohammed, Mohammad H. Semreen, Karem H. Alzoubi, Mohamed Eladl, Yasser Bustanji, Eman Abu-Gharbieh, Waseem El-Huneidi

“…Moreover, Ahr silencing led to the downregulation of major β-cell regulator genes, Ins1, Ins2, Pdx-1, and Glut2, at both the mRNA and protein levels. …”
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Rhegmatogenous retinal detachment: current treatment approaches by A.V. Doga, D.O. Shkvorchenko, L.A. Kryl, M.R. Taevere, D.A. Buryakov

“…&nbsp;Fedorov NMRC “MNTK “Eye Microsurgery”, Moscow, Russian Federation</b> </p> <p> <i>Rhegmatogenous retinal detachment (RRD) is a severe eye disease that may result in low vision or blindness in the lack of surgery. Three major surgical techniques for RRD are currently available, i.e., scleral buckling, pars plana vitrectomy, and pneumatic retinopexy. …”
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Duvelisib is a novel NFAT inhibitor that mitigates adalimumab-induced immunogenicity by Aboli Bhingarkar, Yuyin Wang, Keito Hoshitsuki, Katherine Marie Eichinger, Katherine Marie Eichinger, Sanjay Rathod, Yin Zhu, He Lyu, Andrew T. McNutt, Larry W. Moreland, Lee McDermott, David R. Koes, Christian A. Fernandez

“…IntroductionTNFα inhibitor (TNFi) immunogenicity in rheumatoid arthritis (RA) is a major obstacle to its therapeutic effectiveness. …”
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Suicidal Behaviors Among United States Adolescents: Increasing Clinical and Public Health Challenges by Jhon Ostanin, Helena Miranda, Simon Shugar, Dina Abdo, Maria Carmenza Mejia, Charles H. Hennekens, Panagiota Kitsantas

“…Background/Objectives: Suicide in the United States (US) adolescents is a major clinical and public health problem. In this original investigation, we explored trends in suicidal behaviors (ideation, planning, and attempts) among US adolescents from 2011 to 2021. …”
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Initial Diagnostic Strategies for Helicobacter Pylori in Patients With Bleeding Peptic Ulcers Undergoing Endoscopy: A Cost-Effectiveness Analysis by Michael G. Artin, Josephine Soddano, Sheila D. Rustgi, Zainab Aziz, Francesca Lim, Jeong Yun Yang, Myles A. Ingram, John T. Nathanson, John Y. Kao, Chin Hur

“…Background and Aims: Helicobacter pylori (H. pylori) is a major cause of peptic ulcer disease (PUD) and upper gastrointestinal bleeding. …”
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Breeding for Heat Tolerant Aromatic Rice Varieties and Identification of Novel QTL Regions Associated with Heat Tolerance During Reproductive Phase by QTL-Seq by Surangkana Chimthai, Sulaiman Cheabu, Wanchana Aesomnuk, Siriphat Ruengphayak, Siwaret Arikit, Apichart Vanavichit, Chanate Malumpong

“…Extremely high temperatures resulting from climate change have become a major challenge for increasing rice production. Therefore, our objective was to develop heat-tolerant aromatic rice varieties using the pedigree method, focusing on selecting for seed-setting ability under extremely high temperatures along with the use of single nucleotide polymorphism/insertion and deletion (SNP/InDel) markers to improve aromatic properties and grain quality. …”
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The Effect of Zinc Supplementation on Glycemic, Weight, and Blood Pressure Control in Patients With Type 2 Diabetes Mellitus: A Double‐Blind Randomized Controlled Trial by Mehrab Sayadi, Sara Javadpour Nowbandegani, Fatemeh Balaghi Inalou, Bahman Nazemzadegan, Shirzad Javidi Alsaadi, Mohammadreza Eskandari, Matin Sepehrinia

“…ABSTRACT Backgrounds and Aims Type 2 diabetes and its complications are assumed to be major public health problems globally. Zinc is one of the elements that play a part in insulin secretion and signaling. …”
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Coronary Angiography Safety between Transradial and Transfemoral Access by Santosh Kumar Sinha, Vikas Mishra, Nasar Afdaali, Mukesh Jitendra Jha, Ashutosh Kumar, Mohammad Asif, Ramesh Thakur, Chandra Mohan Varma

“…The aim of study was to evaluate safety, feasibility, and procedural variables of transradial approach compared with transfemoral approach in a standard population of patients undergoing coronary catheterization as one of the major criticisms of the transradial approach is that it takes longer overall procedure and fluoroscopy time, thereby causing more radiation exposure. …”
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Research Review and Prospect of Litchi Fruit Cracking by Xiwen LI, Haoshuang SUN, Xuequn PANG, Zhaoqi ZHANG

“…The review points out that although there are great differences in the susceptibility of fruit cracking among different litchi varieties, so far, we have not been able to identify the key enzymes or major genes related to fruit cracking; compared with other fruits, litchi fruit cracking has a certain degree of specificity, which is manifested in that litchi fruit cracking peaks at the stage from the green fruit stage to the color turning stage, and that the fruits always crack along the suture line with the pulp remaining intact. …”
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Risk factors affecting long-term efficacy of ultrasound-guided high-intensity focused ultrasound treatment for multiple uterine fibroids by Zhenjiang Lin, Feng Xu, Yuan Yuan, Jiaojiao Peng, Jin Luo, Chunmei Gong, Dayong Chen, Yangyang Wang, Donghong Wang, Bing Yang, Lian Zhang

“…Patients with hyperintense uterine fibroids and treated with lower treatment intensity were more likely to experience recurrence than other patients after USgHIFU. No major adverse effects occurred.Conclusions USgHIFU can be used to treat multiple uterine fibroids safely and effectively. …”
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Biomass allocation between reproductive and vegetative organs of Artemisia along a large environmental gradient by Tumenjargal Tsogtsaikhan, Xuejun Yang, Ruiru Gao, Jiangrui Liu, Wenqiang Tang, Guofang Liu, Xuehua Ye, Zhenying Huang

“…We then used standardized major axes regressions to quantify the relationships between reproductive and vegetative organs and linear mixed-effect models to examine the effect of environmental gradients (climate and soil) on biomass allocation patterns. …”
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Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) by Qingyang Zhu, Yuebin Lyu, Keyong Huang, Jinhui Zhou, Wenhao Wang, Kyle Steenland, Howard H. Chang, Stefanie Ebelt, Xiaoming Shi, Yang Liu

“…This study aimed to evaluate the association between three major air pollutants (i.e., PM2.5, O3, and NO2) and cognitive impairment among the Chinese elderly population. …”
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Crustacean Zooplankton Ingestion of Potentially Toxic <i>Microcystis</i>: In Situ Estimation Using <i>mcyE</i> Gene Gut Content Detection in a Large Temperate Eutrophic Lake by Helen Agasild, Margarita Esmeralda Gonzales Ferraz, Madli Saat, Priit Zingel, Kai Piirsoo, Kätlin Blank, Veljo Kisand, Tiina Nõges, Kristel Panksep

“…Crustacean ingestion of toxigenic <i>Microcystis</i> was not related to <i>Microcystis</i> biomass or <i>mcyE</i> gene copy numbers in the environment but was instead related to the abundance of major crustacean grazers. Our findings emphasize the close interaction between crustacean zooplankton and toxigenic <i>Microcystis</i>, indicating that some species may play a more significant role in linking toxic cells within the food web than others.…”
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Minor Antigen Disparities Impede Induction of Long Lasting Chimerism and Tolerance through Bone Marrow Transplantation with Costimulation Blockade by Sinda Bigenzahn, Ines Pree, Christoph Klaus, Nina Pilat, Benedikt Mahr, Elisabeth Schwaiger, Patrick Nierlich, Friedrich Wrba, Thomas Wekerle

“…Significantly superior donor skin graft survival was observed in successfully established long-term chimeras after mHAg matched BMT compared to mHAg mismatched BMT (p<0.05). Both minor and major antigen disparities pose a substantial barrier for the induction of chimerism while the maintenance of tolerance after nonmyeloablative BMT and costimulation blockade is negatively influenced by minor antigen disparities.…”
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Quantitative Characterization for the Micronanopore Structures of Terrestrial Shales with Different Lithofacies Types: A Case Study of the Jurassic Lianggaoshan Formation in the So... by Weiwei Liu, Kun Zhang, Qianwen Li, Zhanhai Yu, Sihong Cheng, Jiayi Liu, Pei Liu, Fengli Han, Liangyi Tang, Zhengwei Li, Xuejiao Yuan, Yiming Yang, Yao Zeng, Chen Zhang

“…Due to the specificity of the geological background, terrestrial strata are widely distributed in the major hydrocarbon-bearing basins in China. In addition, terrestrial shales are generally featured with high thickness, multiple layers, high TOC content, ideal organic matter types, and moderate thermal evolution, laying a solid material foundation for hydrocarbon generation. …”
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