Women’s hospital birth experiences in Harar, eastern Ethiopia: a qualitative study using Roy’s Adaptation Model by Roseanne C Schuster, Nega Assefa, Maleda Tefera, Kedir Teji Roba, Letta Gedefa, Alex Brewis

“…Data were analysed using the four components of Roy’s Adaptation Model (RAM) as a guiding framework of women’s experiences: physiological, self-concept, role and function, and interdependence.Results Various behaviours were identified: under physiological mode, common behaviours identified included labour pain, fatigue, surgical site pain and anaesthesia-related complication. The women’s major problems in self-concept mode were concern for future pregnancy, lack of privacy, newborn health status, relationship with healthcare providers and lack of family support. …”
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Mechanistic insights and atmospheric implications of the degradation reaction of 3-methoxy-1-propanol by reaction with hydroxyl radicals and identification of the end products in t... by Abolfazl Shiroudi, Theo Kurtén, Jacek Czub

“…Successive pathways involve the addition of molecular oxygen to the energized adducts [3M1P]•, forming [3M1P–O2]• peroxy radicals, which primarily react with nitric oxide to produce nitrogen dioxide and the [3M1P–O]• alkoxy radicals. The major degradation products include methyl formate, 3-hydroxypropyl formate, glycolaldehyde, and 3-methoxypropanal.…”
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High-quality DNA extraction for Desmodium gangeticum: A medicinal shrub of Shivalik Himalayas by Shiwani Singh, Maneesh S. Bhandari, Neeraj Dwivedi

“…It contains a vast range of secondary metabolites, majorly polyphenols, that interfere with high-quality deoxyribonucleic acid (DNA) extraction by binding their oxidised form to DNA covalently and rendering it unusable for molecular research. …”
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Integrative multi-omics analysis reveals the role of toll-like receptor signaling in pancreatic cancer by Jie Peng, Jiaao Sun, Youfeng Yu, Qihang Yuan, Yong Zhang

“…Abstract As one of the most destructive and invasive cancers, pancreatic cancer exhibits complex tumor heterogeneity, which has been a major challenge for clinicians in terms of patient treatment and prognosis. …”
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Exploring digital health interventions for pregnant women at high risk for pre-eclampsia and eclampsia in low-income and-middle-income countries: a scoping review by Emily Seto, Anam Shahil Feroz, Noreen Afzal

“…The review reported three major outcomes: maternal health outcomes including maternal and neonatal morbidity and mortality (n=4); usability and acceptability including ease-of-use, and perceived usefulness, (n=5); and intervention feasibility and fidelity including accuracy of device, and intervention implementation (n=7).Conclusion Although the current evidence base shows some potential for the use of digital health interventions for PE/E, more prospective experimental and longitudinal studies are needed prior to recommending the use of digital health interventions for PE/E.…”
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Investigation of 25-hydroxy vitamin D deficiency prevelance in healthy adults aged 18-65 years in Istanbul, Türkiye by Ülfer Gözde

“…Vitamin D deficiency in Istanbul presents a major problem that needs to be remedied.…”
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卒中防治科学传播发展现状与对策建议的研究进展 Research Progress on the Development Status and Countermeasures of Scientific Communication in Stroke Prevention and Treatment... by 张熙1，李杨1，张鹏骞2，3 (ZHANG Xi1, LI Yang1, ZHANG Pengqian2,3 )

“…Abstract: Stroke has become the first cause of death in our country, and it is one of the major diseases threatening our national health. It is necessary and urgent to carry out scientific communication in stroke prevention and treatment. …”
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EFFECT OF DIFFERENT WEED MANAGEMENT PRACTICES ON GROWTH AND YIELD OF INDIAN MUSTARD (BRASSICA JUNCEA) by Puspa Raj Bista, Krishna Bohara, Dhirendra Man Thapa, Keshav Bahadur Karki, Keshar Bahadur Shahi

“…However, weed infestation poses a major challenge to successful mustard cultivation, leading to reduced crop productivity and growth. …”
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Assessing the Impact of Land Use and Land Cover Change on Environmental Parameters in Khyber Pakhtunkhwa, Pakistan: A Comprehensive Study and Future Projections by Mehjabeen Khan, Ruishan Chen

“…The results revealed a 138.02% (4071.98 km²) increase in urban areas from 2000 to 2020, marking urbanization as a major driver of LULC change. Urban expansion strongly correlated with land surface temperature (LST) (R² = 0.89), amplifying the urban heat island effect. …”
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Biodegradable Polymer DES (Ultimaster) vs. Magnesium Bioresorbable Scaffold (BRS Magmaris) in Diabetic Population with NSTE-ACS: A One-Year Clinical Outcome of Two Sirolimus-Elutin... by Piotr Rola, Adrian Włodarczak, Mateusz Barycki, Marek Szudrowicz, Magdalena Łanocha, Jan Jakub Kulczycki, Karol Turkiewicz, Katarzyna Woźnica, Maciej Lesiak, Adrian Doroszko

“…Cardiovascular disease (CVD) with significant involvement of coronary artery disease (CAD) remains a major cause of death and disability among the diabetic population. …”
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Short Cantilever Rock Beam Structure and Mechanism of Gob-Side Entry Retaining Roof in Reuse Period by Jingke Wu, Yun Dong, Jiarui Chen, Chunlei Zhang, Wei Yin, JiHua Zhang, Yongzhen Cheng

“…A dynamic-equilibrium mechanical model of the main roof structure is presented and the formation mechanisms of different types of short cantilever rock beam structures are clarified. The following major conclusions are drawn: (1) Three types of short cantilever rock beam structures occur in the main roof of a gob-side entry retaining during the reuse period, namely, the “short cantilever-articulated rock beam” structure, “short cantilever step rock beam (type I)” structure, and “short cantilever step rock beam (type II)” structure. (2) The stability criterion for these three short cantilever rock beam structures was also determined; that is, when the sliding instability coefficient K ≥ 1, the short cantilever-articulated rock beam structure will form, and when the sliding instability coefficient K < 1, the short cantilever step rock beam (type I or II) will form. (3) The governing law for the thicknesses of the main roof, immediate roof, and coal seam of the short cantilever rock beam structure was clarified; namely, the K-value gradually increases with increases in the thickness of the coal seam, drops sharply and then decreases gradually with increases in the thickness of the main roof, and decreases slowly with increases in the thickness of the immediate roof. …”
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Pancreatic Cancer: Molecular, Biochemical, Chemopreventive, and Therapeutic Aspects by Juan Iovanna, José Luis Neira

“…For a clinically significant effect to be achieved, treatment strategies should either be in the form of (1) a horizontal approach, in which several oncogenic pathways (as those described in this series of reviews) are inhibited; or (2) a vertical approach, whereby multiple levels of a major pathway are targeted. Combination therapies, together with improved diagnostic tools and predictive markers, are ultimately desired in order to improve the bleak outlook for patients diagnosed with PC.…”
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Non-linear oral bioavailability and clinical pharmacokinetics of high-dose Andrographis paniculata ethanolic extract: relevant dosage implications for COVID-19 treatment by Phanit Songvut, Jaratluck Akanimanee, Tawit Suriyo, Nanthanit Pholphana, Nuchanart Rangkadilok, Duangchit Panomvana, Porranee Puranajoti, Jutamaad Satayavivad

“…Safety was assessed through blood chemical analysis and adverse event monitoring after 7 days of ethanolic extract administration.Results Pharmacokinetics of ethanolic extract indicated low plasma levels of the major diterpenoids. The maximum plasma concentration (Cmax) of andrographolide did not exhibit a dose-proportional increase, reaching 6.44 and 11.62 µg/L for single and repeated doses of 60 mg/day, respectively. …”
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Water resources carrying capacity before and after volcanic eruption by M. Dede, S.B. Wibowo, Y. Prasetyo, I.W. Nurani, P.B. Setyowati, S. Sunardi

“…This study aims to analyze water resources carrying capacity before and after the major 2010 eruption of Mount Merapi.METHODS: The value of water resources carrying capacity is derived from that of water availability and the domestic water needs per capita per year. …”
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The Obesity Paradox Revisited: Is Obesity Still a Protective Factor for Patients With High Comorbidity Burden or High-Complexity Procedures? by Hyo Jin Son, BSc, Denise W. Gee, MD, David Gomez, MD, PhD, James J. Jung, MD, PhD

“…We performed an observational study of adult patients undergoing major surgery using the 2016 to 2019 National Surgical Quality Improvement Program database. …”
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Using Linear Mixed-Effects Models to Analyze Historical Trends in Performance Strategies . Commentary on Majid Motavasseli’s Article “Interpretation of Cyclic Form in Bach’s ‘Goldb... by Bruno Gingras

“…Using a tempo measurement database comprising seventy-six selected recordings of the “Goldberg” cycle, I built a linear mixed-effects model predicting the main tempo for each recording from the following parameters: performer, variation number, instrument (piano or harpsichord), year of recording, variation type, and finally mode (major/minor) of the variation. Two statistically significant interactions emerged: a two-way interaction between instrument and mode, and a three-way interaction between instrument, year of recording, and variation type. …”
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Debates on the Role of the US Theatre Missile Defense in Regional Deterrence of Russia and China by O. O. Krivolapov

“…The first section identifies the key points of the MDR concerning the capabilities of regional missile defense for regional deterrence of the major nuclear powers. The author also examines the views of different represen- tatives of the US Department of Defense on this issue, and concludes that the US military-political leadership has a generally positive assessment of the capabilities of the TMD systems to contain Russia and China in case of a regional crisis. …”
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Molecular mechanisms and comparative transcriptomics of diapause in two corn rootworm species (Diabrotica spp.) by Melise C. Lecheta, Chad Nielson, B. Wade French, Emily A.W. Nadeau, Nicholas M. Teets

“…This species complex includes economically significant agricultural pests, notably the western corn rootworm (WCR) and northern corn rootworm (NCR), which cause major losses in maize production. Rootworms undergo an obligate embryonic diapause to synchronize their life cycles with host plants, and we sequenced transcriptomes from both species at five time points (pre-diapause, diapause initiation, diapause maintenance, diapause termination, and post-diapause). …”
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The Mechanism of Acupuncture Therapy for Migraine: A Systematic Review of Animal Studies on Rats by An Y, Zhang J, Ren Q, Liu J, Liu Z, Cao K

“…Our goal is to systematically analyze and evaluate this efficacy mechanism in migraine treatment-related basic research.Methods: To retrieve animal experiments investigating the action mechanism of acupuncture in migraine treatment, We conducted a literature search in major databases, the search period was the inception of each database to April 1, 2024. …”
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Effectiveness of Ascophyllum nodosum and Fucus vesiculosus on Metabolic Syndrome Components: A Real-World, Observational Study by Antonio Nicolucci, Maria Chiara Rossi, Massimiliano Petrelli

“…The likelihood of experiencing a first major cardiovascular event over ten years was estimated using Italian risk charts. …”
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