Current challenges and implications for dengue, chikungunya and Zika seroprevalence studies worldwide: A scoping review. by Camille Fritzell, Dominique Rousset, Antoine Adde, Mirdad Kazanji, Maria D Van Kerkhove, Claude Flamand

“…Estimating the burden of these diseases represents a major challenge that is complicated by the large number of unapparent infections, especially those of dengue fever. …”
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Lidocaine Infusion for the Management of Postoperative Pain and Delirium (LIMPP): protocol for a randomised control trial by Matthias Behrends, Marc Alan Buren, Alekos Theologis, Ariadne Zuraek, Aaron J Clark, Jacqueline M Leung

“…Literature supports the intraoperative use of lidocaine infusions to decrease postoperative opioid requirements, however, whether the use of postoperative lidocaine infusions is associated with lower opioid requirements and subsequently a reduction in postoperative delirium has not been investigated.Methods and analysis The Lidocaine Infusion for the Management of Postoperative Pain and Delirium trial is a randomised, double-blinded study of a postoperative 48-hour infusion of lidocaine at 1.33 mg/kg/hour versus placebo in older patients undergoing major reconstructive spinal surgery at the University of California, San Francisco. …”
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CSF shunts as conduits for metastasis: is there a discrepancy between retrograde and antegrade spread? by Andrea Cuschieri, Robert Pisani, Shawn Agius

“…Methodology A dual systematic review in six major databases was conducted for articles until June 15, 2023, without language restrictions following PRISMA 2020 guidelines and the Cochrane Handbook for Interventional Systematic Reviews. …”
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Meta-analysis of water stress impact on rice quality in China by Shuhui Han, Xianfeng Liu, David Makowski, Philippe Ciais

“…Many studies have been conducted to assess the impact of water stress on yields, but much less attention was paid to rice quality, leading to a poor understanding of the effect of water stress on rice grain quality traits, especially in China - a major rice producer. Although a number of individual experiments have been carried out on this topic, no quantitative synthesis has yet been produced. …”
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Endovascular versus Surgical Lower Extremity Revascularization among Patients with Chronic Kidney Disease by Qingzheng Chen, Jialin Han, Gomathy Parvathinathan, Elsie Ross, Margaret R. Stedman, Tara I. Chang

“…We employed proportional hazard regression to study the primary outcome of major adverse limb events (MALE), defined as a repeat revascularization or amputation. …”
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Trends in blood transfusion and causes of blood wastage: a retrospective analysis in a teaching hospital by Ju-huei Chien, Chao-yuan Yao, Hui-fen Chen, Tsing-Fen Ho

“…Fresh frozen plasma (36.3%), platelet concentrates (15.2%), and cryoprecipitate (14.3%) were the most frequently discarded. Major causes of wastage included excessive or inappropriate orders (22.3%), inability to reissue blood before expiration (16.7%), and incorrect orders (14.6%). …”
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Detection and decontamination of Mycoplasma in cultured cells and viral strains by Glaucia Prado de Andrade, Natália Hettwer Pedroso, Alice Becker, Vinicius Soares dos Santos, Juciane Bonella, José Valter Joaquim Silva Júnior, Rudi Weiblen, Eduardo Furtado Flores

“…ABSTRACT: Contamination of biological products with Mycoplasma spp. represents a major problem for laboratories and vaccine industry. …”
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Dangerous Liaison: Helicobacter pylori, Ganglionitis, and Myenteric Gastric Neurons: A Histopathological Study by Liana Sticlaru, Florica Stăniceanu, Mirela Cioplea, Luciana Nichita, Alexandra Bastian, Gianina Micu, Cristiana Popp

“…Chronic inflammation induced by Helicobacter pylori (H. pylori) infection plays a major role in development of gastric cancer. However, recent findings suggested that progression of inflammation and neoplastic transformation in H. pylori infection are more complex than previously believed and could involve different factors that modulate gastric microenvironment and influence host-pathogen interaction. …”
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Risk Factors Associated with Falls and Fractures Following Prescription of Opioids Among Privately Insured Patients with Osteoarthritis by Stuart Silverman, Patricia Schepman, J. Bradford Rice, Craig G. Beck, William Pajerowski, Alan G. White, Sheena Thakkar, Rebecca L. Robinson, Birol Emir

“…**Conclusion:** Falls and fractures impose a major clinical burden on patients prescribed opioids for OA-related pain management. …”
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Nontuberculous mycobacterium occurrence in biological material and environmental samples covered by epidemiological surveillance in the Republic of Dagestan by M. O. Baratov

“…An investigation for causes of tuberculosis occurrence and persistence on farms, as well as of continuous presence of tuberculin reactor animals on tuberculosis-free farms impeding allergy diagnosis revealed that the major cause is the persistence of pathogenic and nontuberculous acid-fast mycobacteria in the environment. …”
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Mesenchymal Stem Cell Therapy for Acute Myocardial Infarction: Protocol for a Systematic Review and Meta-Analysis by Michael Vincent DiCaro, Brianna Yee, KaChon Lei, Kavita Batra, Buddhadeb Dawn

“…Data on functional cardiac outcomes and major adverse cardiac events were extracted and analyzed as primary outcomes. …”
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Reversible cerebral vasoconstriction syndrome in a methylphenidate-treated patient: a case report by Marie-Noëlle Osmont, Cécile Malrain, Anne-Lise Ruellan, Amine Benchikh, Emmanuelle Herlem, Elisabeth Polard, Lucie-Marie Scailteux

“…After clinical, biological and imaging examinations, clinicians concluded to a highly probable RCVS diagnosis, probably linked to methylphenidate use. Major causes of RCVS were ruled out and the methylphenidate treatment was discontinued. …”
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Development of a Mobile Application Platform for Self-Management of Obesity Using Artificial Intelligence Techniques by Sylvester M. Sefa-Yeboah, Kwabena Osei Annor, Valencia J. Koomson, Firibu K. Saalia, Matilda Steiner-Asiedu, Godfrey A. Mills

“…Obesity is a major global health challenge and a risk factor for the leading causes of death, including heart disease, stroke, diabetes, and several types of cancer. …”
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Resistance-breaking strains of tomato spotted wilt virus hamper photosynthesis and protein synthesis pathways in a virus accumulation-dependent manner in Sw5-carrying tomatoes by Maria Isabella Prigigallo, Ugo Picciotti, Giovanni Bubici

“…Abstract Tomato spotted wilt virus (TSWV; Orthotospovirus tomatomaculae) is one of the major horticultural threats due to its worldwide distribution and broad host range. …”
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The role of climate change and niche shifts in divergent range dynamics of a sister-species pair by Summers, Jeremy, Lukas, Dieter, Logan, Corina J, Chen, Nancy

“…The great-tailed grackle (Quiscalus mexicanus) has expanded its range northward from Texas to Nebraska in the past 40 years, while its closest relative, the boat-tailed grackle (Quiscalus major), has remained tied to the coasts of the Atlantic Ocean and the Gulf of Mexico as well as the interior of Florida. …”
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Lysine Reacts with Cholesterol Hydroperoxide to Form Secosterol Aldehydes and Lysine-Secosterol Aldehyde Adducts by George Wafula Wanjala, Arnold Nola Onyango, David Rasugu Abuga, John Kamathi Muchuna, Calvin Onyango, Moses Makayoto

“…We propose that the amide type adducts, which are major biomarkers of lipid oxidation, are mainly formed by singlet oxygen-mediated oxidation of the carbinolamine adducts.…”
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Microtransesophageal Echocardiographic Guidance during Percutaneous Interatrial Septal Closure without General Anaesthesia by Roel J. R. Snijder, Laura E. Renes, Martin J. Swaans, Maarten Jan Suttorp, Jurrien M. Ten Berg, Martijn C. Post

“…PFO closure was performed in 120 patients, 55 patients (48.6 ± 9.2 years, median device diameter 25 mm, range 23–35 mm) with TEE and 65 patients (mean age 51.0 ± 11.8 years, median device diameter 27 mm, range 23–35 mm) using micro-TEE. There were no major periprocedural complications, especially no device embolizations within all groups. …”
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Next-generation sequencing and immuno-informatics for designing a multi-epitope vaccine against HSV-1-induced uveitis by He Cao, Zhi Cao, Yue Han, Jing Shan

“…Herpes Simplex Virus type 1 (HSV-1) is a major cause of virus-induced uveitis. This study aims to design a novel multi-epitope vaccine targeting HSV-1 glycoproteins B, C, D, H, and L using an immuno-informatics approach, which are essential for viral entry and pathogenesis.MethodsThe study identified epitopes for CD8+ T cells, CD4+ T cells, and B cells within the target glycoproteins. …”
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Lideratge digital en l’educació: una revisió dels últims 50 anys by Aurelio Villa Sánchez, Evelyn Pizarro Fuentes

“…La relació entre el lideratge digital i els resultats acadèmics és evident, per la qual cosa una major inversió en programes de desenvolupament professional i la promoció d'una cultura d'innovació tecnològica poden ampliar significativament les probabilitats d'èxit en la implementació de noves eines digitals. …”
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The burden of medical contraindications to corneal donation: Time for review. by Oliver Dorado-Cortez, Sylvain Poinard, Magali Epinat, Fanny Collange, Sandrine Ninotta, Paul Goin, Jean Luc Perrot, Philippe Gain, Graeme Pollock, Gilles Thuret

“…This approach will result in a highly significant worldwide increase in the availability of corneas for transplant and have an immediate and major impact in reducing corneal blindness across the globe. …”
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