Angiographic Complete versus Clinical Selective Incomplete Percutaneous Revascularization in Heart Failure Patients with Multivessel Coronary Disease by Chieh-Yu Chang, Chun-Chi Chen, I-Chang Hsieh, Ming-Jer Hsieh, Cheng-Hung Lee, Dong-Yi Chen, Ming-Lung Tsai, Ming-Yun Ho, Jih-Kai Yeh, Yu-Chang Huang, Yu-Ying Lu, Chao-Yung Wang, Shang-Hung Chang, Ming-Shien Wen

“…Six hundred patients with HF and MVD submitted to PCI were enrolled. Major adverse cardiac events (MACEs) were defined as a composite of recurrent myocardial infarction, any revascularization, and all-cause mortality at 5 years. …”
Get full text

Rationale, Design, and Baseline Characteristics of Beijing Prediabetes Reversion Program: A Randomized Controlled Clinical Trial to Evaluate the Efficacy of Lifestyle Intervention... by Yingying Luo, Sanjoy K. Paul, Xianghai Zhou, Cuiqing Chang, Wei Chen, Xiaohui Guo, Jinkui Yang, Linong Ji, Hongyuan Wang

“…BPRP was the first study to determine if lifestyle modification and/or pioglitazone could revert prediabetic state to normoglycemia in Chinese population. Major baseline parameters were balanced between two lifestyle intervention groups. …”
Get full text

Expressions of MMPs and TIMP-1 in Gastric Ulcers May Differentiate H. pylori-Infected from NSAID-Related Ulcers by Hsiu-Chi Cheng, Hsiao-Bai Yang, Wei-Lun Chang, Wei-Ying Chen, Yi-Chun Yeh, Bor-Shyang Sheu

“…Background. Two major causes of gastric ulcers are Helicobacter pylori (H. pylori) infection and nonsteroidal anti-inflammatory drug (NSAID) use. …”
Get full text

Bibliometric and visual analysis in the field of electroacupuncture’s analgesia and regulation on negative emotion from 2014 to 2024 by Xubo Huang, Jiajie Gao, Yuxin Ding, Jiali Wang, Junfan Fang, Junfan Fang, Jianqiao Fang, Jianqiao Fang, Junying Du, Junying Du

“…Key institutions, such as Zhejiang Chinese Medical University and Shanghai University of Traditional Chinese Medicine, have made substantial contributions, emphasizing the importance of traditional Chinese medicine in this research area. Major research themes include the modulation of neurotransmitter systems, the role of endogenous opioids, and the impact of EA on chronic pain and mood disorders. …”
Get full text

Trends in genome diversity of small populations under a conservation program: a case study of two French chicken breeds by Bortoluzzi, Chiara, Restoux, Gwendal, Rouger, Romuald, Desnoues, Benoit, Petitjean, Florence, Bosse, Mirte, Tixier-Boichard, Michèle

“…We showed that when the conservation program is consistent over time and does not undergo any major organisational changes (i.e., Barbezieux), the loss of genetic diversity is limited. …”
Get full text

Tumour heterogeneity and personalized treatment screening based on single-cell transcriptomics by Xinying Zhang, Jiajie Xie, Zixin Yang, Carisa Kwok Wai Yu, Yaohua Hu, Jing Qin

“…Tumour cell subpopulations from the five cancers listed above were classified into three major groups corresponding to different treatment strategies. …”
Get full text

Regeneration of Rabbit Auricular Cartilage After the Intravenous Stem Cell Injection by Pavlo Virych, Nadiia Shuvalova, Anton Karas, Galina Karas, Svitlana Chaika, Tetiana Kucherenko, Ganna Minina, Marina Timchenko, Oleg Melnykov, Yurii Minin

“…The restoration of auricular cartilage is a major problem of otolaryngology. The low regenerative capacity of cartilage requires alternative approaches such as cell and tissue engineering. …”
Get full text

CONCEPTUALIZING ENVIRONMENTAL POLICY: AN ANALYSIS OF RUSSIAN AND INTERNATIONAL LEGISLATION IN THE CONTEXT OF ENSURING ENVIRONMENTAL SECURITY IN THE ARCTIC by Elena M. Klyuchnikova, Vladimir A. Masloboev, Vladimir V. Dyadik, Andrey V. Masloboev, Natalia V. Dyadik, Anastasia N. Chapargina

“…To prevent environmental conflicts and find mutually acceptable solutions, it is essential to study the distinctive features of the environmental policies adopted by these major global players. This article presents the results of a study aimed at identifying differences in the environmental security policies embedded in the current legislation of Russia, China, the USA, and the European Union. …”

Biodegradable Mg alloy modified with bioactive exosomes for cardiovascular stent application by Ya-chen Hou, Jing-an Li, Chang Cao, Chang Su, Zhen Qin, Ge Zhang, Jia-cheng Guo, Jun-nan Tang, Jin-ying Zhang, Shao-kang Guan

“…Cardiovascular stent has been widely applied to treat cardiovascular disease (CVD), which is the major disease contribution to mortality in the world wide. …”
Get full text

Advances in Hemodynamic Analysis in Cardiovascular Diseases Investigation of Energetic Characteristics of Adult and Pediatric Sputnik Left Ventricular Assist Devices during Mock Ci... by Alexander A. Pugovkin, Aleksandr G. Markov, Sergey V. Selishchev, Leonie Korn, Marian Walter, Steffen Leonhardt, Leo A. Bockeria, Olga L. Bockeria, Dmitry V. Telyshev

“…We investigate energetic characteristics of adult Sputnik 1 and Sputnik 2 LVADs connected to a hybrid adult mock circulation (HAMC) and also for the Sputnik pediatric rotary blood pump (PRBP) connected to a pediatric mock circulation (PMC). A major improvement of the LV unloading is observed during all simulations for each particular heart failure state when connected to the LVAD, with sequential pump speed increased within 5000–10000 rpm for adult LVADs and 6000–13000 rpm for PRBP with 200 rpm step. …”
Get full text

Protective Effect of Conditioned Medium of Immortalized Human Stem Cells from Exfoliated Deciduous Teeth Against Hair Graying Caused by X-Ray Irradiation via Its Antioxidative Acti... by Yasuhiro Katahira, Eri Horio, Natsuki Yamaguchi, Jukito Sonoda, Miu Yamagishi, Satomi Miyakawa, Fumihiro Murakami, Hideaki Hasegawa, Izuru Mizoguchi, Takayuki Yoshimoto

“…Repetitive subcutaneous administrations of SHED-CM greatly suppressed the development of hair graying, when compared to control medium, resulting in reduced cutaneous expression of 8-hydroxy-2′-deoxyguanosine, the major product of DNA damage induced by reactive oxygen species. …”
Get full text

Sexual dimorphism in basal and post stress parameters of neuro-endocrine-immune complex, metabolome, electrocardiogram, and gastric mucosa at rats by Oksana Fihura, Mykhaylo Korda, Ivan Klishch, Sofiya Ruzhylo, Oksana Melnyk, Walery Zukow, Roman Yanchij, Alyona Vorobienko, Oleksandr Plyska, Dariya Popovych, Igor Popovych

“…The distance between the centroids of the major discriminant root of intact females and males as a measure of sexual dimorphism is 16.2 units. …”
Get full text

Mesenchymal Stem Cell-Derived Extracellular Vesicles for Regenerative Applications and Radiotherapy by Ning Wang, Feifei Ma, Huijuan Song, Ningning He, Huanteng Zhang, Jianguo Li, Qiang Liu, Chang Xu

“…In tissue damage, EVs can be used as an alternative to stem cell therapy, thereby avoiding related complications such as immunological rejection. EVs play a major role in regulating tissue damage, anti-inflammation, pro-proliferation, and immune response, thus providing a diversified and efficient solution for the repair of disease- and radiotherapy-induced tissue damage. …”
Get full text

Effect of Praziquantel on Preventing Delayed Infection of <i>Schistosoma japonicum</i> in Buffaloes and Goats by Xiang Gui, Bing Shao, Haoran Zhong, Rongxue Lv, Hao Li, Ke Lu, Yang Hong, Zhiqiang Fu, Zhenjie Lu, Mengge Xu, Yamei Jin, Jinming Liu

“…Schistosomiasis, caused by <i>Schistosoma japonicum</i>, continues to pose a major public health threat in East Asia, with an estimated 71 million people at risk of infection. …”
Get full text

Segment-based Volatile Organic Compound Emission Characteristics from Different Types of Coking Plants in China by Rumei Li, Yulong Yan, Lin Peng, Yinghui Li, Zhuocheng Liu, Zhanchun Fan, Huanfeng Li, Yang Xu, Cheng Wang, Dongmei Hu, Zhiyong Li

“…Abstract The source profiles, emission factors, and chemical reactivity of volatile organic compounds (VOCs) generated by two typical coking plants, one employing a non-recovery process and the other, a mechanical process, in Shanxi Province, a major coking hub in China, were determined for different segments of coke production during normal operations. …”
Get full text

Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation by A. Chervet, R. Nehme, C. Defois-Fraysse, C. Decombat, C. Blavignac, C. Auxenfans, B. Evrard, S. Michel, E. Filaire, J.-Y. Berthon, A. Dreux-Zigha, L. Delort, F. Caldefie-Chézet

“…Obesity, the fifth leading cause of death globally and linked to chronic low-grade inflammation and development of numerous severe pathologies, is a major public health problem. Fermented foods, probiotics, and postbiotics emerge as promising avenues for combating obesity and inflammation. …”
Get full text

Association between the neutrophil-to-high-density lipoprotein cholesterol ratio with kidney stone risk: a cross-sectional study by Yuan-Zhuo Du, Jia-Qing Yang, Ji-Ming Yao, Chi-Teng Zhang, Yi-Fu Liu

“…ObjectiveKidney stones are a major issue for public health worldwide. Discovering potential clues in identifying at-risk individuals is essential for early detection and timely treatment. …”
Get full text

Implementation of 2% Chlorhexidine Bathing to Reduce Healthcare-Associated Infections Among Patients in the Intensive Care Unit by Hsu-Liang Chang, Tzu-Ying Liu, Po-Shou Huang, Chin-Hwan Chen, Chia-Wen Yen, Hui-Zhu Chen, Shin-Huei Kuo, Tun-Chieh Chen, Shang-Yi Lin, Po-Liang Lu

“…Despite standard interventions, catheter-associated urinary tract infections (CAUTI) and central line-associated bloodstream infections (CLABSI) remain major HAI contributors. This study evaluated the efficacy of daily 2% chlorhexidine gluconate (CHG) bathing in reducing HAI incidence, specifically CAUTI, CLABSI, and multidrug-resistant organisms (MDROs), in a 20-bed ICU at a regional hospital. …”
Get full text

Investigating the Prevalence, Antibiotic Resistance Pattern, and Serotyping of Shigella Isolates from Traditional and Industrial Olivier Salads by Shiva Jahanbakhshi, Mohammad Mehdi Soltan Dallal, Abbas Rahimi Foroushani, Katayoun Samimi-Rad, Seyedeh Zohre Mirbagheri, Ahmad Nasser, Mohammad Reza Mohammadi

“…Background: Food-borne diseases are one of the major problems in developing countries. This study aims to investigate the prevalence, antibiotic resistance pattern, and serotyping of Shigella isolates from Olivier salad. …”
Get full text

Differential gene expression profile in Porphyromonas gingivalis treated human gingival keratinocytes and their role in the development of HNSCC by Dakshinya M, Anitha P, A.S. Smiline Girija, Paramasivam A, Vijayashree Priyadharsini J

“…Background: Periodontitis is considered to be one of the major risk factors associated with cancers of the oral cavity. …”
Get full text