Deformed wing virus coopts the host arginine kinase to enhance its fitness in honey bees (Apis mellifera) by Andrea Becchimanzi, Giovanna De Leva, Rosanna Mattossovich, Serena Camerini, Marialuisa Casella, Giovanni Jesu, Ilaria Di Lelio, Sabrina Di Giorgi, Joachim R. de Miranda, Anna Valenti, Silvia Gigliotti, Francesco Pennacchio

“…Abstract Background Deformed wing virus (DWV) is a major honey bee pathogen that is actively transmitted by the parasitic mite Varroa destructor and plays a primary role in Apis mellifera winter colony losses. …”
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Effects of water nutrient concentrations on stream macroinvertebrate community stoichiometry: a large-scale study by Beck, Miriam, Billoir, Elise, Usseglio-Polatera, Philippe, Meyer, Albin, Gautreau, Edwige, Danger, Michael

“…General differences in the elemental composition among major taxonomic groups and a shift among these groups over the nutrient gradient probably explain the response of community stoichiometry. …”
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3D-CT-derived lung volumes and mortality risk in patients with fibrotic hypersensitivity pneumonitis by Shusuke Yazawa, Yuzo Suzuki, Yuko Tanaka, Koshi Yokomura, Masato Kono, Dai Hashimoto, Atsuki Fukada, Yusuke Inoue, Hideki Yasui, Hironao Hozumi, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Takafumi Suda

“…Background: Hypersensitivity pneumonitis (HP) is a complex and heterogenous interstitial lung disease (ILD) that occurs in susceptible individuals due to certain inhaled antigens. Fibrotic-HP is a major underlying disease of progressive pulmonary fibrosis. …”
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Clinical Characteristics and Outcomes of Deep Vein Thrombosis in Relation to Location: A Retrospective Analysis Study by Majed S. Al Yami PharmD, Abdulmajeed M. Alshehri PharmD, Ghadah M. Alotaibi PharmD, Mariam S. Alsulimani PharmD, Fay M. Alotaibi PharmD, Rawan A. Alotaibi PharmD, Nouf A. Alqahtani PharmD, Lama A. Alhumaidan PharmD, Lubna S. Bin Hadhir PharmD, Norah M. Alebrah PharmD, Sumaya N. Almohareb PharmD, Omar A. Alshaya PharmD, Omar S. Alkhezi PharmD, Osamah M. Alfayez PharmD, Omar A. Almohammed PhD, Amal M. Badawoud PhD

“…The outcomes of this study include evaluating patients’ characteristics for patients with DVT and assessing the incidence of recurrent DVT, major bleeding (MB), VTE-related rehospitalization, and DVT-related inpatient mortality across different types of DVT. …”
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GROWTH, LEAF WATER POTENTIAL, PHOTOSYNTHETIC PIGMENTS, COMPATIBLE SOLUTES AND YIELD COMPONENTS IN COWPEA LANDRACES UNDER SALINITY by Nabi Fahima, Şadji-Ait Kaci Hamida, Chebaani Meriem, Chaker Haddadj Assia, Ounane Sidi Mohamed

“…Soil salinity is a major constraint to food production because it limits crop yield. …”
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Development of <i>Aspergillus oryzae</i> BCC7051 as a Robust Cell Factory Towards the Transcriptional Regulation of Protease-Encoding Genes for Industrial Applications by Sarocha Panchanawaporn, Chanikul Chutrakul, Sukanya Jeennor, Jutamas Anantayanon, Kobkul Laoteng

“…Enzyme-mediated protein degradation is a major concern in industrial fungal strain improvement, making low-proteolytic strains preferable for enhanced protein production. …”
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Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells by Alexandra E. Hill, Eric T. Son, Moumita Paul-Heng, Chuanmin Wang, Shivanjali Ratnaseelan, Martina Denkova, Pouya Faridi, Asolina Braun, Anthony W. Purcell, Nicole A. Mifsud, Alexandra F. Sharland

“…Mass Spectrometry allied with in-vivo generation of activated alloreactive T cell populations and tetramer screening facilitates the identification of endogenous peptides that are directly recognised in complex with allogeneic Major Histocompatibility class I (MHC I) molecules by alloreactive CD8+ T cells. …”
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Factors Associated with Gestational Diabetes Mellitus: A Meta-Analysis by Yu Zhang, Cheng-Ming Xiao, Yan Zhang, Qiong Chen, Xiao-Qin Zhang, Xue-Feng Li, Ru-Yue Shao, Yi-Meng Gao

“…Gestational diabetes mellitus (GDM) is a major public health issue, and the aim of the present study was to identify the factors associated with GDM. …”
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Pharmacokinetics of pradofloxacin, florfenicol, and tulathromycin and response to treatment of steers experimentally infected with Mannheimia hemolytica by Derek M. Foster, Jennifer L. Halleran, Megan E. Jacob, Stephanie Hempstead, Luke B. Borst, Tatiane T. Negrao Watanabe, Hiroko Enomoto, Mark G. Papich

“…Abstract Background Bovine respiratory disease (BRD) is an economically important disease in the beef industry, and a major driver of therapeutic antibiotic use. Pharmacokinetic data of these drugs is relatively limited in diseased animals. …”
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Combining habitat selection, behavioural states, and individual variation to predict fish spatial usage near a barrier by Rachel Mawer, Jelger Elings, Stijn P. Bruneel, Ine S. Pauwels, Eliezer Pickholtz, Renanel Pickholtz, Johan Coeck, Peter L.M. Goethals

“…Riverine barriers are threatening freshwater fish migration, with major impacts on fish populations. Effective management requires understanding of fish movement and behaviour as they approach a barrier and fish pass, which can inform optimal mitigation options and barrier management. …”
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Determinant of Neonatal Visit Coverage Rate in Serdang Bedagai Regency North Sumatra Indonesia by Novita Br Ginting Munthe, Rizanda Machmud, Rima Semiarty, Joserizal Serudji, Adang Bachtiar, Finny Fitry Yani, Denas Symond, Nelwati Nelwati

“…Factors that significantly contributed to increasing coverage of neonatal visits were maternal education (p-value = 0.004, OR = 14.285), maternal knowledge (p-value = 0.000, OR= 75.920), local culture (p-value = 0.000, OR = 57.105), husband/family support (p-value = 0.000, OR = 77.763), and service quality (p-value = 0.000, OR = 47.474). These factors have a major influence in supporting the success of the neonatal visit program, with maternal knowledge and family support being the most dominant factors.. …”
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Isolation and Characterization of the Physiochemical Properties of Brewer’s Spent Grain by Kalidas Mainali, Madhav P. Yadav, Brajendra K. Sharma, Majher I. Sarker, Helen Ngo, Arland Hotchkiss, Stefanie Simon

“…In this investigation, four major fractions were isolated and characterized: Hemicellulose A, Hemicellulose B, cellulosic-rich fraction (CRF), and oligosaccharides. …”
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Photocatalytic improvement mechanism of SnO2/Sn-doped g-C3N4 Z-type heterojunctions for visible-irradiation-based destruction of organic pollutants: Experimental and RSM approaches by Yossor R. Abdulmajeed, Saad H. Ammar, Zaid H. Jabbar, Hind J. Hadi, Mohammed D. Salman, Alaa Jasim Awadh

“…The photocatalyst dose was specified as the major factor in the process. The boosted photoactivity was due to the created Z-type heterojunction among SnO2 and Sn-doped g-C3N4, which provides an excellent separation of photogenerated charge-carriers. …”
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Oral Plaque from Type 2 Diabetic Patients Reduces the Clonogenic Capacity of Dental Pulp-Derived Mesenchymal Stem Cells by Antonella Bordin, Francesca Pagano, Eleonora Scaccia, Matteo Saccucci, Iole Vozza, Noemi Incerti, Antonella Polimeni, Elena Cavarretta, Isotta Chimenti, Elena De Falco

“…Type 2 diabetes (T2D) is a major metabolic disease and a key epigenetic risk factor for the development of additional clinical complications. …”
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Naturally Acquired Antibody Responses to a Synthetic Malaria Antigen AS202.11 by Rebeka Nazareth, Pius Horumpende, Tolbert Sonda, Arnold Ndaro, Edson Mollel, Eliakim Paul, Emmanuel Athanase, Jaffu Chilongola

“…Background. A major challenge to malaria vaccine development is identification of protective epitopes and respective protective immune responses. …”
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Association of Myasthenia Gravis With Autoimmune Thyroid Disease: A Bidirectional Mendelian Randomization Study by Yao Wang, Ke Wang, Jing Lu, Peng Xu, Dongmei Zhang, Xinzhi Chen, Jian Wang

“…Methods Genetic instrumental variables associated with MG and AITD were selected from three major publicly available GWAS databases for MR analysis. …”
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Repetitive Transcranial Magnetic Stimulation: Is it an Effective Treatment for Cancer Pain? by Yanyuan Du, Yaoyuan Li, Jieqing Hu, Ruiying Fang, Yuming Liu, Liu Cai, Ying Song, Susu Ma, Jin Gao, Hanyue Zhang, Baihui Li, Hongtai Xiong, Huibo Yu, Shenglei Yang, Shuduo Zhu, Honggang Zheng

“…Abstract Cancer is a major public health issue, with an estimated 20 million new cases and 9.7 million cancer-related deaths worldwide in 2022. …”
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Allelic and epigenetic DNA variation in relation to F1 heterosis manifestation in F1 hybrids of Capsicum annuum L. by M. N. Shapturenko, S. V. Vakula, L. A. Tarutina, T. V. Nikitinskaya, T. V. Pechkovskaya, L. A. Mishin, L. V. Khotyleva

“…Managing F1 heterosis is one of the major objectives in hybrid crop breeding programs. …”
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Oncolytic Viruses and Immunotherapy for the Treatment of Uveal Melanoma and Retinoblastoma: The Current Landscape and Novel Advances by Merve Kulbay, Nicolas Tuli, Massimo Mazza, Armaan Jaffer, Sarinee Juntipwong, Emily Marcotte, Stuti Misty Tanya, Anne Xuan-Lan Nguyen, Miguel N. Burnier, Hakan Demirci

“…Extraocular extension, recurrence, and metastasis constitute the major challenges of conventional treatments. To overcome these obstacles, immunotherapy, which encompasses different treatment options such as oncolytic viruses, antibody-mediated immune modulations, and targeted immunotherapy, has shown great potential as a novel therapeutic tool for cancer therapy. …”
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A novel approach for unveiling co-occurrence patterns of UV filter mixtures in sunscreens: Prioritization for hazard and risk assessment by Ah-Reum Jo, Ba Reum Kwon, Inae Lee, Jieun Min, Sohyeon Choi, Na-Youn Park, Younglim Kho, Jeongim Park, Ho Kim, Kyungho Choi

“…In conclusion, our study demonstrated that ARM approach can be useful to identify major combinations of UV filters present in sunscreen products, and prioritize the UV filter combinations requiring safety assessment and regulatory attention.…”
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