Network analyses of brain tumor multiomic data reveal pharmacological opportunities to alter cell state transitions by Brandon Bumbaca, Jonah R. Huggins, Marc R. Birtwistle, James M. Gallo

“…In addition to the lack of dedicated drug discovery programs for GBM, extensive intratumor heterogeneity and epigenetic plasticity related to cell-state transitions are major roadblocks to successful drug therapy in GBM. …”
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The Political Complexity of Regional Electricity Policy Formation by Kyungjin Yoo, Seth Blumsack

“…The integration of renewable power supplies into existing electrical grids, or other major technology transitions in electric power, is a complex sociotechnical process. …”
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Unique North American isolates of severe metastatic hypervirulent Klebsiella pneumoniae strain infections with hepatic abscesses seen in young patients within Texas. by Junaid M Alam, Eric N Riha, Haris Ahmed, Hong M Thai, Kevin Garnepudi, Ramesh B Kesavan, Gnananandh Jayaraman, Anna Sangster, Dylan Curry, Heidi A Butz, Lori Smith, Maureen Vowles, Kelly F Oakeson, Erin L Young, Siva T Sarva

“…Country-wide surveillance and whole genome sequencing of these strains is essential to prevent a major public health emergency in the USA.…”
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Comparison of Antioxidant and Alpha-Glucosidase Inhibitory Properties of Moringa peregrina and Ferulago carduchorum Leaf Extracts and Microencapsulation of Superior Plant by Shiva Nouri, Maryam Moslehishad, Seyede Marzieh Hosseini, Mina Etemadi

“…GC-MS was used to identify phytoconstituents of the extract, leading to the determination of 35 components whose major one was vitamin E (10.2%). To ensure its suitability for food fortification, in the third stage, encapsulation of the MP extract was followed. …”
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Assessing the impact of antimicrobial resistance policies on antibiotic use and antimicrobial resistance-associated mortality in children and adults in low and middle-income countr... by Günther Fink, Jay Patel, Kyaw Zay Ya

“…Introduction Antimicrobial resistance (AMR) poses a major threat to global health security today. In recent years, many low and middle-income countries (LMICs) have implemented policies to optimise antibiotic use in both formal and informal healthcare settings. …”
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Assessing Utilization of Information Access Tools in Academic Libraries: A Case Study of National Teachers College Kabale. by Arimpwera, Phiona

“…It was evident that difficulty in locating library materials for quicker information search was the major challenge faced by students in utilizing available information resources at National Teachers College Kabale followed by inadequate ICT Literacy Skills. …”
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Design and Prototyping of a Pineapple Juice Extraction Machine. by Kyazze, Sulaiman

“…The design for different major components was carried out while others were just selected. …”
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The Role of Faith-Based Organizations in HIV/AIDS Prevention in Rwamucucu Sub-County Rukiga District. by Owembabazi, Rabecca

“…The findings revealed that female respondents were highly represented in the study 56% and faith-based organizations were found to be providing welfare services which was represented by 42% of the respondents, the major challenge faced by faith-based organizations was inadequate funding was represented by 47% and the possible strategy was government support which was represented by 35% of the respondents. …”
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Gender Inequality and Elite Working Women in Kirima Sub-County Kanungu District. by Namanya, Precious

“…The findings revealed that pay inequity is one of the most major issues that women employees have to face at their workplace as most of the time despite being more proficient and qualified than fellow male employees, women workers are paid less than males for the same amount. …”
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The Role of Agriculture in The Economic Development of Rural Areas: A Case Study of Kamuganguzi Sub-County Kabale District. by Turyatunga, Apollo

“…The Study research objectives were to determine the major factors that affect the agricultural in economic development of rural areas of Iamuganguzi Sub-county Kabale district, to analyze the impact of agricultural productivity in the economic development of rural areas of Kamuganguzi Sub-county Kabale district, and to suggest possible strategies to improve on the role of agriculture in the economic development of rural areas Kamuganguzi Sub-county Kabale district. …”
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Factors Leading to Low Utilization of PMTCT Services at Rubaare Health Centre IV in Rubaare Town Council Ntungamo District. by Muhairwe, Robert

“…The study concluded that low levels of awareness, inadequate drug supply, and understaffing at health facilities were found to as the major factors affecting mothers accessing and utilizing PMTCT services. …”
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Remedial Education and Academic Performance in Primary Schools: A Case Study of Kashambya Sub-County in Rukiga District. by Twesigye, Glorious

“…The first study objective revealed that schools in Kashambya Sub County were conducting remedial education with 52% of respondents indicating that it develops better learning results as a contribution toward pupils' academic performance The second study objective revealed that private tutoring was the major form of remedial education practiced as represented by a 60% response The third study objective revealed that there was a relationship between the variables. …”
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Assessing The Impact of Records Managers Training on Performance of Municipalities: A case Study Of Kabale Munuciplity Kabale District. by Ninshaba, Clare

“…The collected data was checked and analyzed. tabulated and calculated in percentages and degrees and the results obtained indicated that Records Managers play a very big role in the performance of Kabale Municipality. The major findings of the study about the role of Records Managers were. …”
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A 5-year Retrospective Review of the Presentation Pattern and Management outcomes of Uterine Fibroids in a Nigerian Tertiary Hospital. by Madunatu, Chimezie Michael, Okoro, Chukwuemeka Chukwubuikem, Onyejiaka, Chukwudubem Chinagorom, Enechukwu, Chukwunonso Isaiah, Ofojebe, Chukwuemeka Jude, Ani, Vincent Chinedu, Eleje, George Uchenna, Mbachu, Ikechukwu Innocent, Okafor, Chigozie Geoffrey, Okoro, Amarachukwu Doris, Okafor, Christiana Nkiru, Oguejiofor, Charlotte Blanche, Eze, Stephen Chijioke

“…Although fibroids are considered benign, they are a cause of major quality-of-life issues for women in their reproductive age. …”
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Assessing the Impact of Covid19-Pandemic on the Household Income in Kamuganguzi Sub-County Kabale District. by Arinda, Redeemer Present

“…Additionally, 33.3% of respondents reported that reduced food rations, leading to famine, were a major effect of COVID-19 on families. The study's recommendations included the following: The government should increase spending on immediate health-related expenditures, such as supplies of masks, gloves, other personal protective equipment, ICU beds (Uganda currently has only 55 functional ICU beds, resulting in approximately 1.3 ICU beds per million Ugandans), and ventilators. …”
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Records Management Practices and Business Sustainability of Small-Scale Business: A Case Study of Kindly Services. by Ainebyoona, Ritah

“…The findings of the study indicate that there were challenges faced by small-scale businesses including; limited access, rapid, rapid changes and advancement in technology, absence, of policies, lack of diversity and verification, competition from existing firms, and lack of accountability. 80% of the respondents indicate that lack of diversity and verification was a major challenge faced by records management practices on the sustainability of small-scale businesses. …”
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Role of Social Workers in Enhancing Chronic Care: A Case Study of Kabale Regional Referral Hospital Kabale District. by Musiimenta, Moureen

“…Chronic diseases present a major global healthcare challenge, necessitating integrated and holistic care approaches that go beyond medical treatment. …”
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Women Entrepreneurs and Economic Development Nyagatare Sector, Nyagatare District. by Donatile, Nyirandikubwimana

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Effect of Washing Bays on Water Quality of Rivers: A Case Study of River Rurigita Muko Sub-County Rubanda District Uganda. by Monday, Innocent

“…Findings established the major factors affecting water quality parameters of river Rurigita were; trucks, motorcycles, small car, and cloth washing, solid waste disposal, and town run-offs. …”
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Prevalence of Bovine Fasciolosis,Financial Losses and Risk Factors Associated with the Disease in Lira and Gulu Districts, Northern Uganda by Ogwal, Anthony, Okello, Daniel Micheal, Aliro, Tony, Owiny, David Okello, Ndyomugyenyi, Elly Kurobuza

“…The annual financial loss due to BF infection was USD 89,099. The major risk factors associated with the disease at the farm level were communal grazing in swampy areas (82%) and watering cattle in swamps (71%). …”
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