Expression Analysis of Nitrogen Metabolism-Related Genes Reveals Differences in Adaptation to Low-Nitrogen Stress between Two Different Barley Cultivars at Seedling Stage by Zhiwei Chen, Chenghong Liu, Yifei Wang, Ting He, Runhong Gao, Hongwei Xu, Guimei Guo, Yingbo Li, Longhua Zhou, Ruiju Lu, Jianhua Huang

“…Crop breeding for low-nitrogen tolerance, especially molecular breeding, has become the major route to solving these issues. Therefore, in crops such as barley (Hordeum vulgare L.), it is crucial to understand the mechanisms of low-nitrogen tolerance at the molecule level. …”
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Bisphenol S impairs oocyte quality by inducing gut microbiota dysbiosis by Jiaming Zhang, Xiaoxia Yu, Weidong Li, Yunjing Jiang, Liangran Zhang, Shunxin Wang

“…These findings present a major advance in the understanding of bisphenol S toxicity to oocytes and also provide a preventive strategy.…”
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Detrimental effects of cadmium on male infertility: A review by Nebojša Zečević, Jovana Kocić, Milan Perović, Aleksandar Stojsavljević

“…The review’s data also indicate that exposure to tobacco smoke is a major source of elevated seminal and blood Cd levels in infertile men. …”
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Primary Biliary Cirrhosis-Specific Antimitochondrial Antibodies in Neonatal Haemochromatosis by Daniel S. Smyk, Maria G. Mytilinaiou, Tassos Grammatikopoulos, A. S. Knisely, Giorgina Mieli-Vergani, Dimitrios P. Bogdanos, Diego Vergani

“…AMA strongly reacted against the pyruvate dehydrogenase complex E2 subunit (PDC-E2), the major PBC-specific AMA autoantigen. Anti-PDC-E2 responses in both infant and mother declined over time, being present 2 months after LT (mother and child) and absent 10 months later (mother) and 17 months later (child). …”
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Synergistic Stimulation with Different TLR7 Ligands Modulates Gene Expression Patterns in the Human Plasmacytoid Dendritic Cell Line CAL-1 by Tobias Hilbert, Folkert Steinhagen, Christina Weisheit, Georg Baumgarten, Andreas Hoeft, Sven Klaschik

“…Network analysis revealed IL-1β, IL-6, TNF, and IFN-β as major regulatory nodes, while several minor regulatory nodes were also identified. …”
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The Impact of Bacterial Leaf Blight Disease (<i>Pantoea agglomerans</i>) on Grain Yield and Nutritional Quality of Oat by Ruochen Zhang, Jianjun Wang, Longhai Xue, Malik Kamran, Yue Wang, Xuekai Wei, Guiqin Zhao, Chunjie Li

“…Among these, the bacterial leaf blight disease (LBD) caused by <i>Pantoea agglomerans</i> has been an emerging and prevalent oat disease in Northwest China in recent years and has become a major challenge for oat cultivation in this region. …”
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Donor Identification, Genetic Diversity, Population Structure and Marker–Trait Association Analyses for Iron Toxicity Tolerance Using Rice Landraces by Debanjana Saha, Udit Nandan Mishra, Chittaranjan Sahoo, Seema Tripathy, Uttam Kumar Behera, Susmita Das, Chandrasekhar Sahu, Shiv Datt, Manoj Kumar Rout, Tanmaya Lalitendu Mohanty, Shakti Prakash Mohanty, Saumya Ranjan Barik, Ishwar Chandra Mohanty, Sharat Kumar Pradhan

“…Uptake of excess iron by lowland rice plants causes iron toxicity, which is a major problem in the affected areas. This study investigated molecular diversity, genetic structure, and marker–trait associations for tolerance to iron toxicity in a panel of germplasm lines using microsatellite markers. …”
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Deletion of IRS-1 leads to growth failure and insulin resistance with downregulation of liver and muscle insulin signaling in rats by Yuka Toyoshima, Katsuyuki Nakamura, Yusuke Taguchi, Reiko Tokita, Shiho Takeuchi, Hayato Osawa, Naomi Teramoto, Hidetoshi Sugihara, Fumiaki Yoshizawa, Keitaro Yamanouchi, Shiro Minami

“…Abstract Insulin receptor substrate (IRS)-1 and IRS-2 are major molecules that transduce signals from insulin and insulin-like growth factor-I receptors. …”
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Studying Air Pollutants Origin and Associated Meteorological Parameters over Seoul from 2000 to 2009 by Sunmin Park, Hesham El-Askary, Ismail Sabbah, Hanbin Kwak, Anup K. Prasad, Woo-Kyun Lee, Menas Kafatos

“…We investigate the temporal characteristics of major air pollutants collected from 44 air quality stations over the city of Seoul, Korea, namely, nitrogen dioxide, carbon monoxide, particular matter at 10 microns, and sulfur dioxide (SO2) between 2000 and 2009. …”
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Enrichment Mechanism of the Upper Carboniferous-Lower Permian Transitional Shale in the East Margin of the Ordos Basin, China: Evidence from Geochemical Proxies by Zhifu Wei, Yongli Wang, Gen Wang, Ting Zhang, Wei He, Xueyun Ma, Xiaoli Yu

“…In this paper, shale samples were collected from XX# well of the Taiyuan and Shanxi Formations across the Upper Carboniferous-Lower Permian, which is typical marine-continental transitional shale. The TOC, major elements, and trace elements were measured, and the formation and preservation conditions were investigated using multiple geochemical proxies, including paleoclimate, redox parameters, paleoproductivity, and controls on the accumulation of organic matter. …”
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Evaluation of the Influence of Sensor Geometry and Physical Parameters on Impedance-Based Structural Health Monitoring by L.V. Palomino, K.M. Tsuruta, J.R.V. Mour Jr, D.A. Radea, V. Steffen Jr., D.J. Inman

“…In this paper, the influence of electromagnetic radiation, temperature and pressure variations, and ionic environment have been examined in laboratory. In this context, the major concern is to determine if the impedance responses are affected by these influences. …”
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Analysis of Several PLA2 mRNA in Human Meningiomas by Yves Denizot, Rafael De Armas, Karine Durand, Sandrine Robert, Jean-Jacques Moreau, François Caire, Nicolas Weinbreck, François Labrousse

“…Results indicated that three Ca2+-dependent high molecular weight PLA2 (PLA2-IVA, PLA2-IVB, PLA2-IVC), one Ca2+-independent high molecular weight PLA2 (PLA2-VI) and five low molecular weight secreted forms of PLA2 (PLA2-IB, PLA2-IIA, PLA2-III, PLA2-V, and PLA2-XII) are expressed with PLA2-IVA, PLA2-IVB, PLA2-VI, and PLA2-XIIA as the major expressed forms. PLA2-IIE, PLA2-IIF, PLA2-IVD, and PLA2-XIIB are not detected. …”
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Applicability of the decomposed theory of planned behavior for the evaluation of community-dwelling older adults’ acceptance in continuous usage of robot-assisted board games for c... by Chiu-Mieh Huang, Su-Fei Huang, Yu-Ting Chen, Ching-Hao Chang, Hsiu-Chun Chien, Ying-Jie Chang, Kuei-Yu Huang, Jong-Long Guo

“…The interpersonal influence was a major antecedent of subjective norms. Self-efficacy affects perceived behavioral control. …”
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Characterization and miRNA Profiling of Extracellular Vesicles from Human Osteoarthritic Subchondral Bone Multipotential Stromal Cells (MSCs) by Clara Sanjurjo-Rodríguez, Rachel E. Crossland, Monica Reis, Hemant Pandit, Xiao-nong Wang, Elena Jones

“…Subchondral bone (SB) resident cells and its microenvironment are increasingly recognised to have a major role in OA pathogenesis. The aim of this study was to investigate the EV production from OA SB mesenchymal stromal cells (MSCs) and their possible influence on OA chondrocytes. …”
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Studies on the Dual Cytotoxicity and Antioxidant Properties of Berberis vulgaris Extracts and Its Main Constituent Berberine by Lamyae El khalki, Mounir Tilaoui, Abdeslam Jaafari, Hassan Ait Mouse, Abdelmajid Zyad

“…The present study attempts to investigate the cytotoxic activity of ethanol and ethyl acetate extracts of the Moroccan Berberis vulgaris and its major component berberine, together with exploring their antioxidant properties. …”
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Description of global innovative methods in developing the WHO Community Engagement Package by Jackeline Alger, Don Mathanga, Semeeh Akinwale Omoleke, Noel Juban, Meredith Labarda, Obinna Ikechukwu Ekwunife, Obioma Nwaorgu, Allan Ulitin, Jana Deborah Mier-Alpaño, María Isabel Echavarría, Yolanda Vargas Bayugo, Jose Rene Bagani Cruz, Pauline Marie Padilla Tiangco, Ukam Ebe Oyene, Alberto Ong Jr, Marvinson See Fajardo, Barwani Khaura Msiska, Lorena Abella Lizcano, Natalia Gomez Quenguan, Claudia Ivette Nieto Anderson, Briana Yasmin Beltran, Elsy Denia Carcamo Rodriguez, Eduardo Salomón Núñez, Vera Nkosi-Kholimeliwa, Glory Mwafulirwa-Kabaghe

“…The package comprises four modules organised by major themes such as mobilising communities, strengthening health systems, CE in health emergencies and CE as a driver for health equity.Conclusion After pilot implementation, tools and resources were made available for training and continuous collection of novel CE lessons and experiences from diverse socio-geographical contexts.…”
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Cardiovascular toxicity of tisagenlecleucel in children and adolescents: analysis of spontaneous reports submitted to FAERS by Ganggang Wang, Lin Su, Yanjun Liu, Xiaohan Yang, Yi Li, Qi Mei, Qi Mei, Wen Gao

“…BackgroundThe advent of tisagenlecleucel has been a major advance in the pharmacological treatment of relapsed/refractory B-cell acute lymphoblastic leukemia in children and adolescents. …”
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Exposure to Volatile Organic Compounds in Relation to Visceral Adiposity Index and Lipid Accumulation Product Among U.S. Adults: NHANES 2011–2018 by Ziyi Qian, Chenxu Dai, Siyan Chen, Linjie Yang, Xia Huo

“…In the WQS model, co-exposure to mVOCs was positively correlated with the VAI [β (95%CI): 0.084 (0.022, 0.147)]; CEMA (25.24%) was the major contributor. The result of the BKMR revealed a positive trend of the association between mixed mVOCs and the VAI. …”
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Clinical and Onychoscopy Patterns in Fingernail Onychomycosis—A Study by the International Dermoscopy Society Trichoscopy And Onychoscopy Task Force by Matilde Iorizzo, Bianca Maria Piraccini, Aurora Alessandrini, Francesca Bruni, Laura Vollono, Francesca Pampaloni, Nilton Gioia Di Chiacchio, Nilton Di Chiacchio, Juan Jimenez-Cahue, Chander Grover, Zoe Apalla, Asmahne Souissi, Awatef Kelati, Eirini Kyrmanidou, Elizabeth Lazaridou, Michela Starace

“…mentagrophytes var. interdigitalis in 20 cases, Aspergillus spp. in 8 cases, Candida spp. in 31 cases, and various other fungi in the remaining cases. Major clinical and onychoscopic features observed included onycholysis, subungual hyperkeratosis, leukonychia, chromonychia and absence of the cuticles. …”
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Clinical Outcomes from Unselected “Real-World” Patients with Long Coronary Lesion Receiving 40 mm Biodegradable Polymer Coated Sirolimus-Eluting Stent by Anurag Polavarapu, Raghava Sarma Polavarapu, Jayesh Prajapati, Kamlesh Thakkar, Asif Raheem, Tamanpreet Mayall, Ashok Thakkar

“…The primary endpoints in the study were incidence of major adverse cardiac events (MACE), a miscellany of cardiac death, myocardial infarction (MI), target lesion revascularization (TLR) or target vessel revascularization (TVR), and stent thrombosis (ST) up to 6-month follow-up. …”
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