Response of Soil Bacteria to Short-Term Nitrogen Addition in Nutrient-Poor Areas by Hongbin Yin, Mingyi Xu, Qingyang Huang, Lihong Xie, Fan Yang, Chao Zhang, Gang Sha, Hongjie Cao

“…Increasing nitrogen (N) addition induces soil nutrient imbalances and is recognized as a major regulator of soil microbial communities. However, how soil bacterial abundance, diversity, and community composition respond to exogenous N addition in nutrient-poor and generally N-limited regions remains understudied. …”
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A Disentangled Representation-Based Multimodal Fusion Framework Integrating Pathomics and Radiomics for KRAS Mutation Detection in Colorectal Cancer by Zhilong Lv, Rui Yan, Yuexiao Lin, Lin Gao, Fa Zhang, Ying Wang

“…However, there are still two major problems in existing studies: inadequate single-modal feature learning and lack of multimodal phenotypic feature fusion. …”
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Mass cytometry: exploring the immune landscape of systemic autoimmune and inflammatory diseases in the past fourteen years by Aïcha Kante, Aïcha Kante, Mathieu F. Chevalier, Damien Sène, Damien Sène, Jeanne Chauffier, Jeanne Chauffier, Stéphane Mouly, Stéphane Mouly, Benjamin Glenn Chousterman, Benjamin Glenn Chousterman, Fériel Azibani, Benjamin Terrier, Benjamin Terrier, Théo Pezel, Théo Pezel, Cloé Comarmond, Cloé Comarmond

“…Our analysis highlights the fact that mass cytometry captures major information on cell populations providing insights on the complex pathogenesis of autoimmune diseases. …”
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Screening of native wild Salvia nemorosa populations for chemical compositions, antioxidant activity and UHPLC-HRMS profiling by Raheleh Moshari-Nasirkandi, Abolfazl Alirezalu, Hamid Reza Mohammaddoust Chamanabad, Jussara Amato, Hadi Alipour, Ali Asghari, Atefeh Moshari-Nasirkandi

“…Rosmarinic acid, sagerinic acid, and caffeoylquinic acids (notable polyphenolic compounds with significant pharmacological properties, particularly in the context of their antioxidant, anti-inflammatory, and enzyme inhibitory activities) were identified as the major compounds in S. nemorosa populations. According to hierarchical cluster analysis (HCA) three groups of species were identified based on phytochemical compounds and antioxidant activity. …”
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Long-Term Outcomes of Coronary and Carotid Artery Disease Revascularization in the FRIENDS Study by Fabrizio Tomai, Anna Piccoli, Fausto Castriota, Luca Weltert, Bernhard Reimers, Gabriele Pesarini, Raoul Borioni, Giovanni De Persio, Roberto Nerla, Andrea Pacchioni, Alberto Cremonesi, Flavio Ribichini

“…The cumulative incidence of 5-year major cardiovascular events (MACCE) including cardiovascular death, myocardial infarction (MI), or stroke in the overall population was 12%. …”
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Expression, Purification, and Evaluation of Diagnostic Potential and Immunogenicity of a Recombinant NS3 Protein from All Serotypes of Dengue Virus by Laura Mónica Álvarez-Rodríguez, Angel Ramos-Ligonio, José Luis Rosales-Encina, María Teresa Martínez-Cázares, Aurora Parissi-Crivelli, Aracely López-Monteon

“…Dengue is one of the major public health concerns in the world. Since all the four serotypes are actively circulating in Mexico, there is a need to develop an efficient diagnosis system to improve case management of the patients. …”
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Validated probabilistic approach to estimate flood direct impacts on the population and assets on European coastlines by E. Duo, E. Duo, J. Montes, J. Montes, M. Le Gal, M. Le Gal, T. Fernández-Montblanc, P. Ciavola, P. Ciavola, C. Armaroli

“…It was applied to 16 test cases across Europe and validated against reported impact data in three major reference cases: Xynthia in La Faute-sur-Mer (France) in 2010, Xaver in Norfolk (UK) in 2013, and Emma in Cádiz (Spain) in 2018. …”
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Modeling and Planning a Transmission Network Expansion System in a Regulated Electricity Market by Considering Demand-Side Management via a Developed Fuzzy-Salp Optimization Algori... by Yuying Zhang, Lei Xu, Ji Li, Long Zhang, Zhi Yuan

“…Transmission network expansion planning (TEP) is a major part of power system expansion planning that determines the type, location, and time of installing new lines for the adequacy of power supply. …”
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Testosterone and Adipokines are Determinants of Physical Performance, Strength, and Aerobic Fitness in Frail, Obese, Older Adults by Lina E. Aguirre, Irum Zeb Jan, Kenneth Fowler, Debra L. Waters, Dennis T. Villareal, Reina Armamento-Villareal

“…In conclusion, in frail obese older adults, circulating levels of testosterone, adiponectin, and leptin appear to be important predictors of physical strength and fitness, while inflammation appears to be a major determinant of physical frailty.…”
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Teaching Persian for Academic Purposes: Evaluating the Textbook of Nabz-e Zendegi (Pulse of Life) for International Students Based on Miekley’s Checklist by Amirreza Vakilifard, Nadia Ahmadi Khalkhali

“…The participants were (a) 25 Persian language teachers teaching Persian to non-Persian language learners and (b) 32 non-Persian language learners, majoring in different medicine sciences in Iranian medical universities. …”
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Inhalable nanovesicles loaded with a STING agonist enhance CAR-T cell activity against solid tumors in the lung by Tianchuan Zhu, Yuchen Xiao, Zhenxing Chen, Hanxi Ding, Shoudeng Chen, Guanmin Jiang, Xi Huang

“…Abstract Suppression of chimeric antigen receptor-modified T (CAR-T) cells by the immunosuppressive tumor microenvironment remains a major barrier to their efficacy against solid tumors. …”
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SPAGRM: effectively controlling for sample relatedness in large-scale genome-wide association studies of longitudinal traits by He Xu, Yuzhuo Ma, Lin-lin Xu, Yin Li, Yufei Liu, Ying Li, Xu-jie Zhou, Wei Zhou, Seunggeun Lee, Peipei Zhang, Weihua Yue, Wenjian Bi

“…Abstract Sample relatedness is a major confounder in genome-wide association studies (GWAS), potentially leading to inflated type I error rates if not appropriately controlled. …”
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Effect of Eel Biscuit Supplementation on Height of Children with Stunting Aged 36–60 Months: A Pilot Study by Dewi M. D. Herawati, Siti N. Asiyah, Siska Wiramihardja, Shifa Fauzia, Deni K. Sunjaya

“…Background. Stunting is a major health problem in developing countries. Animal-based supplements can increase the height of children with stunting. …”
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Dielectric spectroscopy and TD-NMR investigation for assessing water solid dynamics in normal and wooden breast chicken by Francesca Soglia, Eleonora Iaccheri, Luca Laghi, Luigi Ragni, Pedro José Fito Suñer, Massimiliano Petracci

“…Dielectric Spectroscopy (DS) and TimeDomain-Nuclear Magnetic Resonance (TD-NMR) were exploited to investigate water and solid dynamics in chicken's Pectoralis major muscles having macroscopically normal appearance (N) and affected by Wooden Breasts (WB) abnormality. 147 PMM were collected and classified as macroscopically normal (N) (N=74) or Wooden Breast (WB) (N=73) based on their visual appearance and manual palpation. …”
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Antiglycating effects of citrus flavonoids and associated mechanisms by Yunli Xiao, Junfeng Shen, Jianfeng Zhan, Limin Guo, Chi-Tang Ho, Shiming Li

“…Herein, we reviewed the up to date progress of the antiglycation effects of citrus flavonoids and associated mechanisms. Major citrus flavonoids, hesperedin and its aglycone, hesperetin, inhibited glycation by scavenging MG forming mono- or di-flavonoid adducts with MG, enhanced the activity of glyoxase-1, activated Akt/Nrf2 signal pathway while inhibiting AGE/RAGE/NF-κB pathway, reduced the formation of Nε-(carboxylmethyl)lysine (CML) and pentosidine, inhibited aldol reductase activity and decreased the levels of fructosamine. …”
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Chemical Identification and Antioxidant Screening of Bufei Yishen Formula using an Offline DPPH Ultrahigh-Performance Liquid Chromatography Q-Extractive Orbitrap MS/MS by Jinyan Wu, Bangrong Cai, Ang Zhang, Peng Zhao, Yan Du, Xuefang Liu, Di Zhao, Liu Yang, Xinguang Liu, Jiansheng Li

“…Furthermore, calycosin had a high content in serum after the oral administration of BYF, indicating that calycosin might be the major antioxidant compound in BYF.…”
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Oral Phosphatidylcholine Improves Intestinal Barrier Function in Drug-Induced Liver Injury in Rats by Meijuan Chen, Haijun Huang, Pengcheng Zhou, Jiajie Zhang, Yining Dai, Danhong Yang, Xuegong Fan, Hongying Pan

“…Phosphatidylcholine (PC) is the major surface-active phospholipid and creates a hydrophobic nature to the surface. …”
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Impact of lifestyle factors on oral cancer risk and prevention: Oral cancer epidemiology by Iadalin Ryntathiang, N. Aravindha Babu, Silambarasan Tamil Selvan, Mukesh Kumar Dharmalingam Jothinathan

“…The world is facing a major health problem represented by oral cancer, which poses a lot of problems mainly in India where it is the third highest prevalent cancer and predominately affects men. …”
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In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration by Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, Sabrina Carrella, Sandro Banfi

“…MicroRNAs (miRNAs), a class of endogenous non-coding RNAs with post-transcriptional regulatory properties, are known to play a major role in retinal function, both in physiological and pathological conditions. …”
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Spi-VSTL: Image data collection platform using off-the shelf hardware for vertically supported crops in state-of-the-art glasshouses by Namal Jayasuriya, Malith Weerasekara, Oula Ghannoum, Yi Guo, Wen Hu

“…Skilled labour for monitoring and maintaining crops in these compact environments has been identified as a major cost and can be reduced using automated image-based crop monitoring. …”
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