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16961
Musical Pitch Perception and Categorization in Listeners with No Musical Training Experience: Insights from Mandarin-Speaking Non-Musicians
Published 2024-12-01“…Among adjacent note pairs at major 2nd pitch distance, the A4–B4 pair was perceived as the easiest to differentiate, while the C4–D4 pair was found to be the most difficult. …”
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16962
Exogenous Melatonin Boosts Heat Tolerance in <i>Rosa hybrida</i> via <i>RhCOMT1</i> Modulation
Published 2024-12-01“…<i>Rosa hybrida</i> is one the most commonly cultivated ornamental plant of economic importance and faces major challenges under heat stress. Melatonin has been widely shown to regulate plant stress response; however, the exact mechanism involved in heat stress in <i>R. hybrida</i> has yet to be determined. …”
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16963
Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits
Published 2020-01-01“…Goat plays a crucial role in human livelihoods, being a major source of meat, milk, fiber, and hides, particularly under adverse climatic conditions. …”
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16964
Feature selection enhances peptide binding predictions for TCR-specific interactions
Published 2025-01-01“…IntroductionT-cell receptors (TCRs) play a critical role in the immune response by recognizing specific ligand peptides presented by major histocompatibility complex (MHC) molecules. …”
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16965
Clonality and the Phenotype–Genotype Correlation of Antimicrobial Resistance in <i>Acinetobacter baumannii</i> Isolates: A Multicenter Study of Clinical Isolates from Romania
Published 2025-01-01“…Our findings note a 91.52% frequency of extensively drug-resistant carbapenem-resistant <i>A. baumannii</i> (XDR CRAB) phenotype amongst clinical isolates from multiple hospitals in two major cities from northwestern and central Romania, harboring multiple antibiotic resistance genes such as bla<i><sub>OXA-23-like</sub></i> in 108 (91.5%) isolates, bla<i><sub>OXA-24/40-like</sub></i> in 88 (74.6%) isolates, bla<i><sub>NDM</sub></i> in 29 (25%) isolates, <i>ArmA</i> in 75 (63.6%) isolates, and <i>ant(3″)-I</i> in 69 (58.5%) isolates and <i>sul1</i> in 113 (95.76%) isolates. …”
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16966
Comparative Analysis of Antioxidant Potency and Phenolic Compounds in Fruit Peel of Opuntia robusta, Opuntia dillenii, and Opuntia ficus-indica Using HPLC-DAD Profiling
Published 2024-01-01“…Ten phenolic compounds were identified, with isorhamnetin being the most abundant flavonoid measuring 7184.09 μg/g, while sinapic acid was identified as the major phenolic acid measuring 1806.36 μg/g. Opuntia robusta exhibited the highest total phenolic content, total flavonoids, and total phenolic acids measuring 5583.19 mg GAE 100 g−1, 21041.03 μg/g, and 3265.17 μg/g, respectively. …”
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16967
P53 and Expression of Immunological Markers May Identify Early Stage Thyroid Tumors
Published 2013-01-01“…Background. Besides its major role in cell proliferation, DNA repair, and apoptosis, functional p53 protein is involved in the induction of antitumor cytotoxic-T-cell activity against carcinoma cells. …”
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16968
Functional Metaplasticity of Hippocampal Schaffer Collateral-CA1 Synapses Is Reversed in Chronically Epileptic Rats
Published 2017-01-01“…Hence, studying the cellular and molecular cascades involved in the key mechanism of information storage in the brain, synaptic plasticity, has led to enormous knowledge in this field. A major open question applies to the interdependence between synaptic plasticity and its behavioral correlates. …”
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16969
Checklist of amphipod crustaceans (Crustacea: Amphipoda) in Slovenia
Published 2021-12-01“…Our work revealed two major knowledge gaps. Marine species records come from occasional sampling campaigns, and we suggest that this group calls for a more systematic research. …”
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16970
Ecological drivers of evolution of swine influenza in the United States: a review
Published 2025-12-01“…Influenza A viruses (IAVs) pose a major public health threat due to their wide host range and pandemic potential. …”
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16971
Achieving Complete Remission of Hepatocellular Carcinoma: A Significant Predictor for Recurrence-Free Survival after Liver Transplantation
Published 2019-01-01“…Liver transplantation (LT) is a curative treatment for hepatocellular carcinoma (HCC) and the underlying primary liver disease; however, tumor recurrence is still a major issue. Therefore, the aim of this study was to assess predictors and risk factors for HCC recurrence after LT in patients within and outside the Milan criteria with a special focus on the impact of different bridging strategies. …”
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16972
Global and regional burden of bloodstream infections caused by carbapenem-resistant Gram-negative bacteria in 2019: A systematic analysis from the MICROBE database
Published 2025-04-01“…Methods: We extracted data from the Measuring Infectious Causes and Resistance Outcomes for Burden Estimation database, which includes the estimated burden of 23 pathogens and 88 pathogen-drug combinations across 12 major infectious syndromes globally in 2019. The number and rate of deaths, as well as disability-adjusted life-years linked to bloodstream infections, were systematically analyzed. …”
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16973
DNA vaccines as promising immuno-therapeutics against cancer: a new insight
Published 2025-01-01“…Following the internalization of plasmids into cells, their genes are expressed and the tumor antigens are loaded on major histocompatibility molecules to be presented to T-cells. …”
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16974
Detection of Francisellaceae and the differentiation of main European F. tularensis ssp. holarctica strains (Clades) by new designed qPCR assays
Published 2025-01-01“…In addition, we developed a qPCR assay to differentiate the major clades (B.4, B.6 and B.12 [B.71 and B.72]) of F. tularensis ssp. holarctica strains. …”
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16975
Neutralization by Insulin of the Hypertensive Effect of Dermcidin Isoform 2: An Environmentally Induced Diabetogenic and Hypertensive Protein
Published 2014-01-01“…The effect of dermcidin isoform 2 (dermcidin), an environmentally induced stress protein, was investigated on the genesis of diabetes mellitus and hypertension, the two major atherosclerotic risk factors. The role of dermcidin as an atherosclerotic risk factor related to the impaired systemic insulin level was investigated. …”
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16976
Cuspal Displacement Induced by Bulk Fill Resin Composite Polymerization: Biomechanical Evaluation Using Fiber Bragg Grating Sensors
Published 2016-01-01“…Polymerization shrinkage is a major concern to the clinical success of direct composite resin restorations. …”
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16977
Aortic Valve Surgery in Patients Over 75 Years Old: Early Results and Predictors of Hospital Mortality
Published 2025-01-01“…Hospital mortality was 4.1%. The incidence of major perioperative complications such as low cardiac output, stroke, respiratory problems, bleeding, atrial fibrillation, wound infection, and conduction disturbances was 6.8%, 2.7 %, 4.1%, 2.7 %, 21.9 %, 2.6%, and 4.2 %. …”
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16978
Radiotherapy Suppresses Bone Cancer Pain through Inhibiting Activation of cAMP Signaling in Rat Dorsal Root Ganglion and Spinal Cord
Published 2016-01-01“…Radiotherapy is one of the major clinical approaches for treatment of bone cancer pain. …”
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16979
Changes in Quality and Flavor of Chopped Chili Peppers in Ceramic Jars during Fermentation
Published 2025-02-01“…In order to investigate changes in the quality, flavor and major aroma components of pickled chilies in ceramic jars during fermentation, this study used headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry (HS-SPME-GC-MS) to analyze the volatile substances of pickled chilies in ceramic jars from a certain producer after storage for 1–5 years and determined their physicochemical indexes and total bacterial counts. …”
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16980
OMIC Technologies and Vaccine Development: From the Identification of Vulnerable Individuals to the Formulation of Invulnerable Vaccines
Published 2019-01-01“…The presence of these nonresponders/undervaccinated individuals represents a major health and economic burden to society, which will become particularly difficult to address in settings with limited public resources. …”
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