The mutational landscape of Staphylococcus aureus during colonisation by Francesc Coll, Beth Blane, Katherine L. Bellis, Marta Matuszewska, Toska Wonfor, Dorota Jamrozy, Michelle S. Toleman, Joan A. Geoghegan, Julian Parkhill, Ruth C. Massey, Sharon J. Peacock, Ewan M. Harrison

“…Survival and persistence during colonisation are likely major drivers of S. aureus evolution. Here we applied a genome-wide mutation enrichment approach to a genomic dataset of 3060 S. aureus colonization isolates from 791 individuals. …”
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Fish Gut Metabarcoding Detects Diets and Parasites Simultaneously by Dilli Prasad Rijal, Per Arneberg, Tanja Hanebrekke, Torild Johansen, Daniela Sint, Michael Traugott, Mette Skern‐Mauritzen, Jon‐Ivar Westgaard

“…While invertebrates were the major food source of redfish, our analysis indicated only two taxa of vertebrates that significantly contributed to the diet composition. …”
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Research progress on climate change adaptation strategies to control invasive crop pest in sub-Saharan Africa: a bibliometric and systematic review by Eméline Sêssi Pélagie Assèdé, Eméline Sêssi Pélagie Assèdé, Calvince Ouko Othoo, Calvince Ouko Othoo, Ahmadou Ly, Gobena Bayisa, Temesgen Gashaw Tarkegn, Temesgen Gashaw Tarkegn, Mègnissè Zohoun, Anje-Jokebed N’goran

“…In conclusion, while invasive pests represent a major plant health crisis in sub-Saharan Africa, this review highlights innovative adaptation strategies. …”
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CD154 Induces Interleukin-6 Secretion by Kidney Tubular Epithelial Cells under Hypoxic Conditions: Inhibition by Chloroquine by Antoine Dewitte, Julien Villeneuve, Sébastien Lepreux, Marion Bouchecareilh, Xavier Gauthereau, Claire Rigothier, Christian Combe, Alexandre Ouattara, Jean Ripoche

“…Inflammation is a major contributor to tubular epithelium injury in kidney disorders, and the involvement of blood platelets in driving inflammation is increasingly stressed. …”
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Diagnosis and Treatment of Low Anterior Resection Syndrome by Masaaki Miyo, Emi Akizuki, Koichi Okuya, Ai Noda, Masayuki Ishii, Ryo Miura, Momoko Ichihara, Maho Toyota, Kohei Okamoto, Tatsuya Ito, Yuji Akiyama, Ichiro Takemasa

“…., which is a patient-reported outcome measure to evaluate the severity of bowel dysfunction following rectal surgery by scoring the major symptoms of LARS, facilitates the diagnosis and assessment of LARS and enables international comparison and validation through the use of validated scores generated according to the international standards. …”
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The Health Impacts of Air Pollution in the Context of Changing Climate in Africa: A Narrative Review with Recommendations for Action by Lynn M Atuyambe, Raphael E Arku, Natasha Naidoo, Thandi Kapwata, Kwaku Poku Asante, Guéladio Cissé, Belay Simane, Caradee Y Wright, Kiros Berhane

“…Introduction: Despite the broad improvement in air quality, air pollution remains a major leading global risk factor for ill health and deaths each year. …”
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Low carbon effects of super large diameter shield directly cutting piles project: A case study in China by Yifan Chen, Xiangsheng Chen, Jian Ouyang, Xiang Shen, Shuhua Huang, Jian Sheng, Liang Zhang

“…The model is used to calculate the carbon emissions of cutting pile projects for two different shield tunnel diameters, employing three major construction methods. According to the results, a systematic analysis is conducted on the carbon emission proportions and key influencing factors at each stage of the pile underpinning method. …”
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Study protocol of the PRINCESS trial—PReoperative INtermittent fasting versus CarbohydratE loading to reduce inSulin resiStance versus standard of care in orthopaedic patients: a r... by Markus W Hollmann, Abraham H Hulst, Benedikt Preckel, Jeroen Hermanides, Ayla Y Stobbe, Eline S de Klerk, Robert van Wilpe, Arthur J Kievit, Kee Fong Choi, Mireille F M van Stijn

“…A total of 75 orthopaedic patients presenting for elective intermediate to major surgery at a Dutch academic hospital will be randomly assigned to a control group (standard preoperative fasting), a TRF group or a CHL group. …”
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Detection of Gastroesophageal Reflux Esophagitis Using 2-fluoro-2-deoxy-d-glucose Positron Emission Tomography by Min-Kuei Tsai, Hueisch-Jy Ding, Hsueh-Chou Lai, Kuo-Yang Yen, Chia-Ing Li, Yu-Yi Lin, Kai-Yuan Cheng, Keh-Bin Wang, Chia-Hung Kao

“…Gastroesophageal reflux disease (GERD) is a common disease and a major upper gastrointestinal problem. The purpose of the present study is to evaluate the use of noninvasive 2-fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET) to detect gastroesophageal reflux esophagitis. …”
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Chemical composition and antimicrobial activity of Artemisia annua (L.) essential oil against different fish pathogens by F. Sakhaie, M. Adel, R. Safari, F. Firouzbakhsh, A. Nosrati Movafagh, T. Stadtlander

“…In the present study, the composition of the essential oil and antimicrobial activity from aerial parts of Artemisia annua growing wild in north of Iran was investigated. The major ingredients of the essen-tial oil of A. annua were camphor (29.2%), 1.8-cineole (13.3%), tetradecanol (6.16%), β-selinene (5.82%) and pinocarvone (3.86%). …”

Antiallergic Effect of the Alpha-Cyclodextrin Moringin Complex in Rat Basophilic Leukaemia (RBL-2H3) Cell Line by Ebtisam Yousef A. Alnakeeb, Ahmad Faizal Abdull Razis, Kim Wei Chan, Chau Ling Tham, Yee Han Chan, Anwar Salm Kalifa Kafo, Nuzul Noorahya Jambari, Patrick Rollin, Florence Djedaini-Pilard

“…Allergic diseases (ADs) are a major concern when it comes to public well-being. …”
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Operation time as a prognostic indicator on postoperative complications following percutaneous nephrolithotomy by Alireza Pakdel, Abdolreza Mohammadi, Amirreza Shamshirgaran, Ehsan Zemanati Yar, Leila Zareian Baghdadabad, Farshid Alaeddini, Roghayeh Koohi Ortakand, Leonardo Oliveira Reis, Seyed Reza Hosseini, Seyed Mohammad Kazem Aghamir

“…Logistic regression models were fitted and the ability of the surgery time to predict complications, major complications, and systemic inflammatory response syndrome was evaluated using receiver-operating characteristic curves. …”
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Preliminary species diversity and community phylogenetics of wood-inhabiting basidiomycetous fungi in the Dabie Mountains, Central China reveal unexpected richness by Xiang-Yang Liu, Shi-Liang Liu, Hao-Wen Wei, Xue-Wei Wang, Jia Yu, Shan Shen, Li-Wei Zhou

“…Abstract Wood-inhabiting fungi have important economic values as well as playing a major ecological role in forest ecosystem cycles. …”
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Genome sequences of four Ixodes species expands understanding of tick evolution by Alexandra Cerqueira de Araujo, Benjamin Noel, Anthony Bretaudeau, Karine Labadie, Matéo Boudet, Nachida Tadrent, Benjamin Istace, Salima Kritli, Corinne Cruaud, Robert Olaso, Jean-François Deleuze, Maarten J. Voordouw, Caroline Hervet, Olivier Plantard, Aya Zamoto-Niikura, Thomas Chertemps, Martine Maïbèche, Frédérique Hilliou, Gaëlle Le Goff, Jindřich Chmelař, Vilém Mazák, Mohamed Amine Jmel, Michalis Kotsyfakis, José María Medina, Michael Hackenberg, Ladislav Šimo, Fotini A. Koutroumpa, Patrick Wincker, Petr Kopáček, Jan Perner, Jean-Marc Aury, Claude Rispe

“…We have determined gene families that have undergone major amplifications during the evolution of ticks, while an expression atlas obtained for I. ricinus reveals striking patterns of specialization both between and within gene families. …”
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AIPerf: Automated Machine Learning as an AI-HPC Benchmark by Zhixiang Ren, Yongheng Liu, Tianhui Shi, Lei Xie, Yue Zhou, Jidong Zhai, Youhui Zhang, Yunquan Zhang, Wenguang Chen

“…We utilize Operations Per Second (OPS), which is measured in an analytical and systematic approach, as a major metric to quantify the AI performance. We perform evaluations on various systems to ensure the benchmark’s stability and scalability, from 4 nodes with 32 NVIDIA Tesla T4 (56.1 Tera-OPS measured) up to 512 nodes with 4096 Huawei Ascend 910 (194.53 Peta-OPS measured), and the results show near-linear weak scalability. …”
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Treatment of Aortic and Iliac Artery Aneurysms with Multilayer Flow Modulator: Single Centre Experiences by Cengiz Ovalı, Aykut Şahin, Murat Eroğlu, Sinan Balçın, Sadettin Dernek, Mustafa Behçet Sevin

“…MFM can be preferred as an alternative approach in the treatment of aorta and iliac artery aneurysms including major lateral branches. The present results should be confirmed with additional future studies conducted with larger patient groups for longer periods.…”
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Targeting SLITRK4 Restrains Proliferation and Liver Metastasis in Colorectal Cancer via Regulating PI3K/AKT/NFκB Pathway and Tumor‐Associated Macrophage by Xiaojiao Sun, Junling Zhang, Bingqi Dong, Qingqing Xiong, Xin Wang, Yanlun Gu, Zhiqi Wang, Huiyu Liu, Jixin Zhang, Xu He, Hongjin Liu, Yi Zhong, Chuxiao Yi, Xiaowei Chi, Zhenming Liu, Xiaocong Pang, Yimin Cui

“…Abstract Liver metastasis is the major cause of death in colorectal cancer (CRC) due to the lack of effective treatment. …”
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Atractylenolide-I prevents abdominal aortic aneurysm formation through inhibiting inflammation by Shuxiao Chen, Xiaotian Liu, Xincheng Zhou, Weixiao Lin, Minting Liu, Haoran Ma, Keli Zhong, Qiming Ma, Chengjian Qin, Chengjian Qin

“…Atractylenolide-I (ATL-I) is a major bioactive component of Rhizoma Atractylodis Macrocephalae that exerts anti-inflammatory effects in various diseases. …”
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Chemical Constituents and Antimicrobial and Antioxidant Activities of Essential Oil from Dried Seeds of Xylopia aethiopica by Samba Fama Ndoye, Yoro Tine, Insa Seck, Lalla Aicha Ba, Seydou Ka, Ismaila Ciss, Abda Ba, Seynabou Sokhna, Moussa Ndao, Rokhaya Sylla Gueye, Nango Gaye, Abdoulaye Diop, Jean Costa, Julien Paolini, Matar Seck

“…Forty-nine compounds were identified in the essential oil with 1,8-cineole (16.3%), β-pinene (14.8%), trans-pinocarveol (9.1%), myrtenol (8.3%), α-pinene (5.9%), and terpinen-4-ol (5.6%) as major components. The antimicrobial activity of this essential oil was studied using disk diffusion and broth microdilution methods on four bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa) and one fungus (Candida albicans). …”
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Autonomous detection of nail disorders using a hybrid capsule CNN: a novel deep learning approach for early diagnosis by Gunjan Shandilya, Sheifali Gupta, Salil Bharany, Ateeq Ur Rehman, Upinder Kaur, Hafizan Mat Som, Seada Hussen

“…Abstract Major underlying health issues can be indicated by even minor nail infections. …”
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