Local Government Unit’s Support to Educational Programs as Viewed by the Citizens: The Case of Lezo, Aklan by Cecilia T Reyes, Cecile O. Legaspi, Clyde G. Abayon, Tomas O. Ortega, Anna Mae. C. Relingo, Mary Eden M. Teruel, Jyanee Loi D. Yecla

“…Female respondents were targeted for even numbered questionnaires while male respondents were targeted for odd numbers. The four major core concepts namely awareness, availment, satisfaction and need for action were used in measuring the rating of the respondents and presented in frequency and percentage distributions. …”
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Hormone replacement therapy, menopausal age and lifestyle variables are associated with better cognitive performance at follow-up but not cognition over time in older-adult women i... by Tamlyn J. Watermeyer, Tamlyn J. Watermeyer, Sarah Gregory, Sarah Gregory, Emmi Leetham, Chinedu T. Udeh-Momoh, Chinedu T. Udeh-Momoh, Chinedu T. Udeh-Momoh, Chinedu T. Udeh-Momoh, Chinedu T. Udeh-Momoh, Graciela Muniz-Terrera, Graciela Muniz-Terrera

“…Two regression models were employed: one analyzing cognitive performance at follow-up and another examining changes in cognitive scores over time.ResultsResults indicate that while age, education, HRT use, age at menopause, alcohol consumption, and diet were associated with cognitive function at a single later time point, only age remained a significant predictor when modeling cognition over time.DiscussionThese findings suggest that while HRT, menopausal age and lifestyle factors may support cognitive stability, they do not necessarily predict cognitive decline in post-menopausal older women. A major limitation of the current work is the lack of detail regarding HRT use, such as formulation, timing and duration; caveats that future studies should address. …”
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Characterization of aroma compounds of Pu-erh ripen tea using solvent assisted flavor evaporation coupled with gas chromatography-mass spectrometry and gas chromatography-olfactome... by Bei Wang, Qing Meng, Lin Xiao, Ruili Li, Chunhai Peng, Xueli Liao, Jingna Yan, Honglin Liu, Guanhua Xie, Chi-Tang Ho, Huarong Tong

“…Results demonstrated that 58 major volatile compounds and 24 aroma active substances of Pu-erh ripen tea were identified by GC-MS and GC-O analysis. …”
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Increased Frequency of CD4+ CD25+ FoxP3+ T Regulatory Cells in Pulmonary Tuberculosis Patients Undergoing Specific Treatment and Its Relationship with Their Immune-Endocrine Profil... by Ariana Díaz, Natalia Santucci, Bettina Bongiovanni, Luciano D’Attilio, Claudia Massoni, Susana Lioi, Stella Radcliffe, Griselda Dídoli, Oscar Bottasso, María Luisa Bay

“…Tuberculosis (TB) is a major health problem requiring an appropriate cell immune response (IR) to be controlled. …”
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TSMGA: Temporal-Spatial Multiscale Graph Attention Network for Remote Sensing Change Detection by Xiaoyang Zhang, Genji Yuan, Zhen Hua, Jinjiang Li

“…In the field of remote sensing change detection, accurately capturing temporal change information and efficiently integrating multilevel information is a major challenge. In order to extend the sensory domain and optimize the information fusion, the model is able to capture temporal-spatial change features more accurately and improve the accuracy of change detection. …”
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Artificially intelligent detection of retinal pigment sign using P3S-Net for retinitis pigmentosa analysis by Syed Muhammad Ali Imran, Abida Hussain, Nema Salem, Muhammad Arsalan

“…Image segmentation is a major and crucial problem in medical imaging. It is the foundation for clinical diagnostic methods, treatments, and computer-assisted disease diagnosis (CAD). …”
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Evaluation of Arterial Stiffness for Predicting Future Cardiovascular Events in Patients with ST Segment Elevation and Non-ST Segment Elevation Myocardial Infarction by Oguz Akkus, Durmus Yildiray Sahin, Abdi Bozkurt, Kamil Nas, Kazım Serhan Ozcan, Miklós Illyés, Ferenc Molnár, Serafettin Demir, Mücahit Tüfenk, Esmeray Acarturk

“…Aortic pulse wave velocity (PWV), aortic augmentation index (AI), systolic area index (SAI), heart rate, and pulse pressure were higher; ejection fraction, the return time (RT), diastolic reflex area (DRA), and diastolic area index (DAI) were significantly lower in patients with major cardiovascular events. However, PWV, heart rate, and ejection fraction were independent indicators at development of MACE. …”
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Contributions of Limb Joints to Energy Absorption during Landing in Cats by Xueqing Wu, Baoqing Pei, Yuyang Pei, Nan Wu, Kaiyuan Zhou, Yan Hao, Wei Wang

“…Additionally, the elbow and hip are recognized as major contributors to energy absorption during landing. …”
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Prevalence of Undernutrition and Its Associated Factors among Children below Five Years of Age in Bure Town, West Gojjam Zone, Amhara National Regional State, Northwest Ethiopia by Desalegne Amare, Ayenew Negesse, Baye Tsegaye, Birtukan Assefa, Birehanu Ayenie

“…Background. Malnutrition is the major public health problem over the world. Developing countries are highly affected. …”
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Fetal and neonatal cardiac tumor diagnosed as Tuberous Sclerosis associated rhabdomyomas resulting from novel pathogenic missense variant detected in TSC2 gene: A case report by Aya Kawasaki, MD, Hidefumi Tonoki, MD, PhD, Osamu Sasaki, MD, PhD, Yoko Matsushita, MD, PhD, Michiko Watari, MD, PhD, Nobuhiro Takahashi, MD, Satoko Fujieda, MD

“…The cardiac tumors were diagnosed as rhabdomyomas, a major clinical feature of TS, since the penetrance of this gene variants are thought to be 100%. …”
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CYP2C19 polymorphism and coronary in-stent restenosis: A systematic review and meta-analysis [version 3; peer review: 2 approved, 1 approved with reservations] by Ivana Purnama Dewi, Irawan Yusuf, Agussalim Bukhari, Muzakkir Amir, Vitriyaturrida ., Yusra Pintaningrum, Idar Mappangara, Hendy Bhaskara Perdana Putra

“…Background In-stent restenosis (ISR) remains a major drawback in coronary stenting. The association between the CYP2C19 loss of function (LOF) gene and the prevalence of ISR after coronary stenting remains controversial. …”
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Protective Effects of Chitosan Oligosaccharide Against Lipopolysaccharide-Induced Inflammatory Response and Oxidative Stress in Bovine Mammary Epithelial Cells by Ziwei Lin, Yanlong Zhou, Ruiwen Chen, Qiuyan Tao, Qiwen Lu, Qianchao Xu, Haibin Yu, Ping Jiang, Zhihui Zhao

“…COS has a variety of biological functions, including anti-inflammatory and antioxidant activities. Mastitis is a major disease in dairy cows that has a significant impact on animal welfare and production. …”
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Achieving Hepatitis C Micro-Elimination in Chinese Injecting Drug Users: A Dynamic Network Modeling Study by Ying Chen, Yun Bao, Mengxia Yan, Huajie Jin, Kaijie Yao, Chi Zhang, Wen Li, Bin Wu

“…People who inject drugs (PWID), a major driver of HCV transmission, are an essential part of China’s hepatitis C elimination program. …”
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A model-based factorization method for scRNA data unveils bifurcating transcriptional modules underlying cell fate determination by Jun Ren, Ying Zhou, Yudi Hu, Jing Yang, Hongkun Fang, Xuejing Lyu, Jintao Guo, Xiaodong Shi, Qiyuan Li

“…When bench-tested across 239 datasets, MGPfactXMBD showed advantages in major quantity-control metrics, such as branch division accuracy and trajectory topology, outperforming most established methods. …”
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Assessment of the nitrogen fertilizer split-application on maize grain yield and profitability on Nitisols of South-Kivu, Eastern D.R. Congo by Patient M. Zamukulu, Espoir M. Bagula, Jean M. Mondo, Géant B. Chuma, Gisèle M. Bulonza, Sarah Mwaluke, Yannick Mugumaarhahama, Céphas B. Mwimangire, Eloïs L. Cinyabuguma, Antoine K. Lubobo, Gustave N. Mushagalusa

“…Abstract Soil depletion constitutes a major challenge for agriculture and food security in highlands of eastern Democratic Republic of Congo (DRC). …”
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Transitioning from Oxime to the Next Potential Organophosphorus Poisoning Therapy Using Enzymes by Rauda A. Mohamed, Keat K. Ong, Noor Azilah M. Kasim, Norhana A. Halim, Siti Aminah M. Noor, Victor F. Knight, Nurul Najwa Ab. Rahman, Wan Md Zin W. Yunus

“…For years, organophosphorus poisoning has been a major concern of health problems throughout the world. …”
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Zoonotic transmission of novel Influenza A variant viruses detected in Brazil during 2020 to 2023 by Paola Cristina Resende, Dennis M. Junqueira, Caroline Tochetto, Maria Ogrzewalska, Fernando C. Motta, Jonathan Lopes, Luciana Appolinario, Larissa Macedo, Braulia Caetano, Aline Matos, Thauane Silva, Elisa Cavalcante Pereira, Leticia Ferreira Lima, Irina Riediger, Maria do Carmo Debur, Guilherme Nardi Becker, Aline Andrade, Acácia Maria Lourenço Francisco Nasr, Rosana Aparecida Piler, Ana Carolina Dalla Vecchia, Walquíria Almeida, David Brown, Rejane Schaefer, Marilda M. Siqueira

“…Genomes recovered were closely related to Brazilian swIAVs of three major lineages (1 A.3.3.2/pdm09, 1B/human-like, and H3.1990.5), including three H1N1v, two H1N2v, two H3N2v and one H1v. …”
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Elevated Concentration of Defensins in Hepatitis C Virus-Infected Patients by Ehab H. Mattar, Hussein A. Almehdar, Abdullah A. AlJaddawi, Isam ElDin M. Abu Zeid, Elrashdy M. Redwan

“…Hepatitis C virus (HCV) is the major etiological agent of human non-A and non-B hepatitis, affecting around 180 million people worldwide. …”
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Total Antioxidant Status in Type 2 Diabetic Patients in Palestine by Akram T. Kharroubi, Hisham M. Darwish, Mutaz A. Akkawi, Abdelkareem A. Ashareef, Zaher A. Almasri, Khaldoun A. Bader, Umaiyeh M. Khammash

“…The objective of this study was to compare the level of total antioxidant status (TAS) in type 2 diabetic and normal Palestinian subjects as well as the major factors influencing TAS levels. A sample of convenience composed of 212 type 2 diabetic and 208 normal subjects above the age of 40 were recruited. …”
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Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer by Jinbao Chen, Chenqi Wu, Kun Yu, Jinpei Liu, Jiahua Yang, Wei Li, Xiaoxia Tang, Yihai Shi, Ke Xu, Yi Chen, Xiaoyu Qin

“…Abstract Background Metastasis and chemoresistance are often major challenges in advanced-stage colorectal cancer. …”
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